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  1. 173941
    “…L’examen objectivait une fièvre à 39 °C, un état hémodynamique stable, une pression artérielle à 11/06 mmHg et une tachycardie à 110 bpm. …”
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    Vascularite à anticorps anti-membrane basale glomérulaire secondaire au Covid-19 : observation inédite !
  2. 173942
    por Rojas, Manuel, Rodríguez, Yhojan, Hernández, Juan Carlos, Díaz-Coronado, Juan C., Vergara, José Alejandro Daza, Vélez, Verónica Posada, Mancilla, Jessica Porras, Araujo, Iván, Yepes, Jairo Torres, Ricaurte, Oscar Briceño, Pardo-Oviedo, Juan Mauricio, Monsalve, Diana M., Acosta-Ampudia, Yeny, Ramírez-Santana, Carolina, García, Paula Gaviria, Landinez, Lina Acevedo, Correales, Luisa Duarte, Grass, Jeser Santiago, Pérez, Cristian Ricaurte, López, Gustavo Salguero, Mateus, Nataly, Mancera, Laura, Devia, Ronald Rengifo, Orjuela, Juan Esteban, Parra-Moreno, Christian R., Buitrago, Andrés Alfonso, Ordoñez, Inés Elvira, Osorio, Claudia Fabra, Ballesteros, Nathalia, Patiño, Luz H., Castañeda, Sergio, Muñoz, Marina, Ramírez, Juan David, Bastard, Paul, Gervais, Adrian, Bizien, Lucy, Casanova, Jean-Laurent, Camacho, Bernardo, Gallo, Juan Esteban, Gómez, Oscar, Rojas-Villarraga, Adriana, Pérez, Carlos E., Manrique, Rubén, Mantilla, Rubén D., Anaya, Juan-Manuel
    Publicado 2022
    “…RESULTS: An early but transient increase in IgG anti-S1-SARS-CoV-2 antibody levels at day 4 post-transfusion was observed (Estimated difference [ED], − 1.36; 95% CI, − 2.33 to − 0.39; P = 0.04). However, CP was not associated with viral load reduction in any of the points evaluated. …”
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    Safety and efficacy of convalescent plasma for severe COVID-19: a randomized, single blinded, parallel, controlled clinical study
  3. 173943
    “…FINDINGS: Between Dec 11, 2020, and June 27, 2021, blood samples were taken from 220 people younger than 65 years (median age 51 years [IQR 39–61]; 103 [47%] had previously had a SARS-CoV-2 infection) and 268 people aged 65 years or older of LTCFs (median age 87 years [80–92]; 144 [43%] had a previous SARS-CoV-2 infection). …”
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    Antibody and cellular immune responses following dual COVID-19 vaccination within infection-naive residents of long-term care facilities: an observational cohort study
  4. 173944
    por Zhao, Zhiguo, Huang, Fei
    Publicado 2022
    “…In order to better explore the role of the training program, The five factor emotion scale of this study adopts the five factor scale (ffmq) jointly prepared by Baer et al in 2006 [, translated and revised by Deng Yuqin et al., the scale has 39 questions, including observation, conscious action, description, non reaction and non judgment. …”
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    CONSTRUCTION AND PRACTICE OF INNOVATION AND ENTREPRENEURSHIP EDUCATION ECOSYSTEM IN LOCAL COLLEGES AND UNIVERSITIES FROM THE PERSPECTIVE OF EMOTION REGULATION -- A CASE STUDY OF HUAIYIN INSTITUTE OF TECHNOLOGY
  5. 173945
    “…The mean difference was 9.06% (−11.42–29.64) for BSF and −5.44% (−50.3–39.45) for M72. Both membrane-50, rabbit-50 and rabbit-100 predicted the superiority of Interceptor(®) G2 over Interceptor(®) ITN for the resistant strain on M72. …”
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    Modified World Health Organization (WHO) Tunnel Test for Higher Throughput Evaluation of Insecticide-Treated Nets (ITNs) Considering the Effect of Alternative Hosts, Exposure Time, and Mosquito Density
  6. 173946
    “…A significant difference was also observed between mildly affected and severely/critically ill patients [31/78 (39.7%) vs. 44/294 (15%), respectively) (p<0.001)], but not between severely and critically ill patients [28/200 (14,%) vs. 16/94 (17,1%), (p=n.s.)]. …”
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    Prevalence of Allelic Variants and Clonality of IGHV1-69 Expressing B-Cells in Patients with Different Severity of COVID 19 Disease
  7. 173947
    “…[ACR20: (RR 1.24, 95% CI 1.14–1.35, p < 0.00001); ACR50: (RR 1.96, 95% CI 1.62–2.39, p <0.00001); ACR70: (RR 1.91, 95% CI 1.41–2.57, p < 0.0001)]; [DAS28-ESR: (MD) −1.43, 95% CI −1.73 to −1.12, p < 0.00001]. 3) Compared with MTX + leflunomide (LEF), ACR20, ACR50, ACR70, and DAS28-ESR of IGU + MTX had no significant difference [ACR20: (RR 1.06, 95% CI 0.94–1.19, p = 0.38); ACR50: (RR 1.10, 95% CI 0.66–1.84, p = 0.72); ACR70: (RR 1.20, 95% CI 0.45–3.20, p = 0.71); DAS28-ESR: (MD −0.02, 95% CI −0.13 to −0.10, p = 0.77)]. 4) Compared with MTX + hydroxychloroquine (HCQ), IGU + MTX was superior in improving DAS28-ESR (MD −2.16, 95% CI −2.53 to −1.79, p < 0.00001). 5) Compared with MTX + tripterygium glycosides (TGs), IGU + MTX was more effective in improving DAS28-ESR (MD −0.94, 95% CI −2.36 to 0.48, p = 0.19). 6) There were no significant differences in adverse events (AEs) between the groups of IGU vs. …”
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    Effectiveness and Safety of Iguratimod Monotherapy or Combined With Methotrexate in Treating Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
  8. 173948
    “…At 6 months postpartum, fewer women in the screening group were identified as possibly depressed compared to the control group (RR 0.59, 95% confidence interval (CI) 0.39 to 0.89) and mean EPDS scores were also statistically significantly lower in the screened group (standardized mean difference 0.34 lower (95% CI 0.15 to 0.52 lower)). …”
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    Screening for depression among the general adult population and in women during pregnancy or the first-year postpartum: two systematic reviews to inform a guideline of the Canadian Task Force on Preventive Health Care
  9. 173949
    “…The highest detected viral load was greater among those with Delta variant infections (median [IQR], 4.4 [3.9-5.1] log(10) copies/mL) than those with infections from variants not of interest or concern (median [IQR], 1.9 [1.1-3.6] log(10) copies/mL; P = .009) or those with Alpha variant infections (median [IQR], 2.6 [2.3-3.4] log(10) copies/mL; P = .006). …”
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    Assessment of Clinical and Virological Characteristics of SARS-CoV-2 Infection Among Children Aged 0 to 4 Years and Their Household Members
  10. 173950
    “…In multivariable modelling, lower anti-SARS-CoV-2 S1 RBD antibody concentrations were independently associated with infliximab (geometric mean ratio 0·15 [95% CI 0·11–0·21]; p<0·0001), tofacitinib (0·52 [CI 0·31–0·87]; p=0·012), and thiopurine (0·69 [0·51–0·95]; p=0·021), but not with ustekinumab (0·64 [0·39–1·06]; p=0·083), or vedolizumab (0·84 [0·54–1·30]; p=0·43). …”
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    COVID-19 vaccine-induced antibody and T-cell responses in immunosuppressed patients with inflammatory bowel disease after the third vaccine dose (VIP): a multicentre, prospective, case-control study
  11. 173951
    “…Following YCHD treatment, the serum levels of TBIL (176.39 ± 17.03 μmol/L vs 132.23 ± 13.88 μmol/L, P < 0.01), DBIL (141.41 ± 14.66 μmol/L vs 106.43 ± 10.88 μmol/L, P < 0.01), ALT (332.07 ± 34.34 U/L vs 269.97 ± 24.78 U/L, P < 0.05), and AST (411.44 ± 47.64 U/L vs 305.47 ± 29.36 U/L, P < 0.01) decreased. …”
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    The mechanism of Yinchenhao decoction in treating obstructive-jaundice-induced liver injury based on Nrf2 signaling pathway
  12. 173952
    “…However, within this group, analysis according to BRCA status showed that BRCA mutant patients (n = 35) presented higher rates of progression and worse survival outcomes under subsequent platinum than BRCA wild type patients (n = 39), with statistically significant differences. …”
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    Multicenter Real-World Data of Subsequent Chemotherapy after Progression to PARP Inhibitors in a Maintenance Relapse Setting
  13. 173953
    “…While 99 (77%) patients in COMPERA and 133 (72%) patients in ASPIRE with classical IPAH were female, there was a lower proportion of female patients in the IPAH and a lung phenotype cohort (95 [35%] COMPERA; 75 [54%] ASPIRE), which was similar to group 3 pulmonary hypertension (336 [37%] COMPERA; 148 [39%] ASPIRE]). Response to pulmonary arterial hypertension therapies at first follow-up was available from COMPERA. …”
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    Phenotyping of idiopathic pulmonary arterial hypertension: a registry analysis
  14. 173954
    por Tarín-Vicente, Eloy José, Alemany, Andrea, Agud-Dios, Manuel, Ubals, Maria, Suñer, Clara, Antón, Andrés, Arando, Maider, Arroyo-Andrés, Jorge, Calderón-Lozano, Lorena, Casañ, Cristina, Cabrera, José Miguel, Coll, Pep, Descalzo, Vicente, Folgueira, María Dolores, García-Pérez, Jorge N, Gil-Cruz, Elena, González-Rodríguez, Borja, Gutiérrez-Collar, Christian, Hernández-Rodríguez, Águeda, López-Roa, Paula, de los Ángeles Meléndez, María, Montero-Menárguez, Julia, Muñoz-Gallego, Irene, Palencia-Pérez, Sara Isabel, Paredes, Roger, Pérez-Rivilla, Alfredo, Piñana, María, Prat, Nuria, Ramirez, Aída, Rivero, Ángel, Rubio-Muñiz, Carmen Alejandra, Vall, Martí, Acosta-Velásquez, Kevin Stephen, Wang, An, Galván-Casas, Cristina, Marks, Michael, Ortiz-Romero, Pablo L, Mitjà, Oriol
    Publicado 2022
    “…All participants presented with skin lesions; 141 (78%) participants had lesions in the anogenital region, and 78 (43%) in the oral and perioral region. 70 (39%) participants had complications requiring treatment: 45 (25%) had a proctitis, 19 (10%) had tonsillitis, 15 (8%) had penile oedema, six (3%) an abscess, and eight (4%) had an exanthem. …”
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    Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study
  15. 173955
    “…Lipodystrophy and INSR had similar fasting insulin levels and compared to controls, had elevated A4 (Lipodystrophy vs INSR vs control: 8.8 [5.0-10.9] vs 9.4 [4.7-19.3] vs 2.4 [1.6-3.2]) and T (4.1 [2.8-6.1] vs 11.7 [3.9-37.5] vs 0.9 [0.6-1.2]). Compared to controls (data above), only Lipodystrophy (but not INSR) had elevated 11-oxyandrogens, including 11OHA4 (8.2 [4.3-12.7]), 11KA4 (1.4 [1.0-1.7]), and 11KT (2.7 [1.7-2.9]). 11OHA4: A4 ratios were lower in INSR vs control (0.2 [0.1-1.2] vs 1.3 [1.0-1.9]), but not Lipodystrophy vs controls. …”
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    RF10 | PMON221 11-Oxygenated-Androgens in Females with Severe Insulin Resistance
  16. 173956
    “…A análise do perfil epidemiológico corresponde ao: tipo de doação (espontanea, reposição, autologa), tipo de doador (primeira vez, repetição, esporádico), gênero (masculino e feminino), faixa etária (> 18 anos, 18-29 anos, 30-39 anos, 40-49 anos, 50-59 anos e maiores de 60 anos). …”
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    PERFIL DOS CANDIDATOS À DOAÇÃO DE SANGUE APÓS PICO A PANDEMIA DA COVID-19
  17. 173957
    “…However, abortion ratios were highest among adolescents (aged ≤19 years) and lowest among women aged 25–39 years. Abortion rates decreased from 2011 to 2020 among all age groups. …”
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    Abortion Surveillance — United States, 2020
  18. 173958
    “…RÉSULTATS: Soixante patients ont été colligés, l’âge moyen était de 50,82 ± 12,39 ans. Les maladies immuno-inflammatoires étaient : la maladie Crohn (n = 28), polyarthrite rhumatoïde (n = 9), rectocolite hémorragique (n = 5), maladie de Behçet (n = 5), lupus érythémateux systémique (n = 3), syndrome de Sjögren (n = 3), sarcoïdose (n = 2), maladie de Takayasu (n = 1). …”
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    La réponse humorale aux vaccins anti-SARS-CoV-2 chez les patients suivis pour maladies immuno-inflammatoires
  19. 173959
    “…La moyenne des CRP avant R était de 115,4 ± 82,5 mg/L (66 patients) versus 31,9 ± 45,0 mg/L après (39 patients). Les D-dimères avant R étaient de 1728,5 ± 2101 ng/mL pour 79 patients. …”
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    Utilisation du Remdésivir et impact potentiel sur divers paramètres biologiques
  20. 173960
    “…For SOC, the AUC for CLR, EMB, and RFB was 60 mg*h/L (t(1/2)=6h), 39 mg*h/L (t(1/2)=8h), and 1.5 mg*h/L (t(1/2)=45h), respectively, similar to human lung concentrations. …”
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    1697. Dose-response Studies of the Novel Bacterial Leucyl-tRNA Synthetase Inhibitor, Epetraborole, in the Intracellular Hollow Fiber System Model of Mycobacterium avium complex Lung Disease
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