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1721
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1722“…PATIENTS AND METHODS: 61 female patients with hip osteoarthritis were treated with cementless THA with anatomically designed hydroxyapatite-coated femoral stems and ceramic-ceramic bearing surfaces (ABG-II). Of the 39 eligible patients between the ages of 41 and 78 years, 12 had normal systemic BMD and 27 had osteopenia or osteoporosis. …”
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1723por Vu, Thanh-Huyen T., Stamler, Jeremiah, Liu, Kiang, McDermott, Mary M., Lloyd-Jones, Donald M., Pirzada, Amber, Garside, Daniel B., Daviglus, Martha L.“…CONCLUSIONS: LR profile in younger adulthood (ages 25 to 45) is associated with the lowest prevalence of PAD and borderline PAD 39 years later.…”
Publicado 2012
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1724
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1725por Horenstein, Alberto L, Chillemi, Antonella, Zaccarello, Gianluca, Bruzzone, Santina, Quarona, Valeria, Zito, Andrea, Serra, Sara, Malavasi, Fabio“…Our data show that this new axis is driven by the nucleotide-metabolizing ectoenzymes CD38 (an NAD(+) nucleosidase), the ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1, also known as CD203a or PC-1) and the 5′ ectonucleotidase (5′-NT) CD73, while bypassing the canonical catabolic pathway mediated by the nucleoside tri- and diphosphohydrolase (NTPDase) CD39. To determine the relative contributions of these cell surface enzymes to the production of adenosine, we exploited a human T-cell model allowing for the modular expression of the individual components of this alternative pathway upon activation and transfection. …”
Publicado 2013
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1726por Watson, G W, Wickramasekara, S, Palomera-Sanchez, Z, Black, C, Maier, C S, Williams, D E, Dashwood, R H, Ho, E“…SUV39H1 is thus identified as a novel mediator of sulforaphane cytotoxicity in PC3 cells. …”
Publicado 2014
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1727“…Here, novel N-terminal Lys39 has been identified as a key residue during LPA-type agonist binding and LPA(1) activation. …”
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1728
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1729
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1730por Waldén, Markus, Krosshaug, Tron, Bjørneboe, John, Andersen, Thor Einar, Faul, Oliver, Hägglund, Martin“…METHODS: We assessed videos from 39 complete ACL tears recorded via prospective professional football injury surveillance between 2001 and 2011. …”
Publicado 2015
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1731“…Ni(39+x)Mn(50)Sn(11−x) (x = 0.5, 1.0, 1.5 and 2) alloys comprise multiple martensite nanostrips of nanocrystallites when cast in small discs, for example, ∼15 mm diameter and 8 mm width. …”
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1732por Henson, Katherine E., Reulen, Raoul C., Winter, David L., Bright, Chloe J., Fidler, Miranda M., Frobisher, Clare, Guha, Joyeeta, Wong, Kwok F., Kelly, Julie, Edgar, Angela B., McCabe, Martin G., Whelan, Jeremy, Cutter, David J., Darby, Sarah C., Hawkins, Mike M.“…METHODS: The Teenage and Young Adult Cancer Survivor Study cohort comprises 200 945 5-year survivors of cancer diagnosed at 15 to 39 years of age in England and Wales from 1971 to 2006, and followed to 2014. …”
Publicado 2016
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1733por Gerő, Domokos, Torregrossa, Roberta, Perry, Alexis, Waters, Alicia, Le-Trionnaire, Sophie, Whatmore, Jacqueline L., Wood, Mark, Whiteman, Matthew“…We have therefore evaluated two novel mitochondria-targeted anethole dithiolethione and hydroxythiobenzamide H(2)S donors (AP39 and AP123 respectively) at preventing hyperglycemia-induced oxidative stress and metabolic changes in microvascular endothelial cells in vitro. …”
Publicado 2016
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1734por Huang, Feng, Chen, Maogen, Chen, Weiqian, Gu, Jian, Yuan, Jia, Xue, Yaoqiu, Dang, Junlong, Su, Wenru, Wang, Julie, Zadeh, Homayoun H., He, Xiaoshun, Rong, Limin, Olsen, Nancy, Zheng, Song Guo“…Moreover, we demonstrated that GMSCs inhibited human PBMC-initiated xenogenic responses via CD39/CD73/adenosine and IDO signals. These findings suggest the potential for GMSCs to suppress human immune responses in immune system-mediated diseases, offering a potential clinical option to be used for modulating GVHD and autoimmune diseases.…”
Publicado 2017
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1735
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1736por An, Rui, Xi, Cong, Xu, Jian, Liu, Ying, Zhang, Shumiao, Wang, Yuemin, Hao, Yuewen, Sun, Lijun“…Cotransfer of angiogenic and antiapoptotic genes could be the basis of new gene therapy strategies for myocardial infarction. In this study, rAAV-PR39-ADM, coexpressing antimicrobial peptide (PR39) and adrenomedullin (ADM), was designed with the mediation of recombinant adeno-associated virus. …”
Publicado 2017
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1737“…RESULTS: Heterologous expression of the Thermoanaerobacter pseudethanolicus 39E bdhA gene, that encodes an alcohol dehydrogenase, in Clostridium thermocellum significantly increased resistance to furan derivatives at concentrations found in acid-pretreated biomass. …”
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1738por Bartunek, Jozef, Terzic, Andre, Davison, Beth A., Filippatos, Gerasimos S., Radovanovic, Slavica, Beleslin, Branko, Merkely, Bela, Musialek, Piotr, Wojakowski, Wojciech, Andreka, Peter, Horvath, Ivan G., Katz, Amos, Dolatabadi, Dariouch, El Nakadi, Badih, Arandjelovic, Aleksandra, Edes, Istvan, Seferovic, Petar M., Obradovic, Slobodan, Vanderheyden, Marc, Jagic, Nikola, Petrov, Ivo, Atar, Shaul, Halabi, Majdi, Gelev, Valeri L., Shochat, Michael K., Kasprzak, Jaroslaw D., Sanz-Ruiz, Ricardo, Heyndrickx, Guy R., Nyolczas, Noémi, Legrand, Victor, Guédès, Antoine, Heyse, Alex, Moccetti, Tiziano, Fernandez-Aviles, Francisco, Jimenez-Quevedo, Pilar, Bayes-Genis, Antoni, Hernandez-Garcia, Jose Maria, Ribichini, Flavio, Gruchala, Marcin, Waldman, Scott A., Teerlink, John R., Gersh, Bernard J., Povsic, Thomas J., Henry, Timothy D., Metra, Marco, Hajjar, Roger J., Tendera, Michal, Behfar, Atta, Alexandre, Bertrand, Seron, Aymeric, Stough, Wendy Gattis, Sherman, Warren, Cotter, Gad, Wijns, William“…METHODS AND RESULTS: This multinational, randomized, double-blind, sham-controlled study was conducted in 39 hospitals. Patients with symptomatic ischaemic heart failure on guideline-directed therapy (n = 484) were screened; n = 348 underwent bone marrow harvest and mesenchymal stem cell expansion. …”
Publicado 2017
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1739por Liu, Jian-Hua, Jing, Dong-Yang, Wang, Liang-Liang, Li, Yang, Quan, Wei, Fang, Jian-Cheng, Liu, Wu-Ming“…We have studied the (85)Rb polarization of two types of hybrid optical pumping SERF magnetometers based on (39)K-(85)Rb-(4)He and (133)Cs-(85)Rb-(4)He respectively. …”
Publicado 2017
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1740por Chiu, David Kung-Chun, Tse, Aki Pui-Wah, Xu, Iris Ming-Jing, Di Cui, Jane, Lai, Robin Kit-Ho, Li, Lynna Lan, Koh, Hui-Yu, Tsang, Felice Ho-Ching, Wei, Larry Lai, Wong, Chun-Ming, Ng, Irene Oi-Lin, Wong, Carmen Chak-Lui“…Using hepatocellular carcinoma (HCC) as a cancer model, we show that hypoxia, through stabilization of hypoxia-inducible factor-1 (HIF-1), induces ectoenzyme, ectonucleoside triphosphate diphosphohydrolase 2 (ENTPD2/CD39L1), in cancer cells, causing its overexpression in HCC clinical specimens. …”
Publicado 2017
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