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174021por Katureebe, Agaba, Zinszer, Kate, Arinaitwe, Emmanuel, Rek, John, Kakande, Elijah, Charland, Katia, Kigozi, Ruth, Kilama, Maxwell, Nankabirwa, Joaniter, Yeka, Adoke, Mawejje, Henry, Mpimbaza, Arthur, Katamba, Henry, Donnelly, Martin J., Rosenthal, Philip J., Drakeley, Chris, Lindsay, Steve W., Staedke, Sarah G., Smith, David L., Greenhouse, Bryan, Kamya, Moses R., Dorsey, Grant“…In Walukuba, over the 28-mo post-intervention period, universal LLIN distribution was associated with no change in the incidence of malaria (0.39 episodes PPY pre-intervention versus 0.20 post-intervention; adjusted rate ratio [aRR] = 1.02, 95% CI 0.36–2.91, p = 0.97) and non-significant reductions in the TPR (26.5% pre-intervention versus 26.2% post-intervention; aRR = 0.70, 95% CI 0.46–1.06, p = 0.09) and HBR (1.07 mosquitoes per house-night pre-intervention versus 0.71 post-intervention; aRR = 0.41, 95% CI 0.14–1.18, p = 0.10). …”
Publicado 2016
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174022por Mason‐Jones, Amanda J, Sinclair, David, Mathews, Catherine, Kagee, Ashraf, Hillman, Alex, Lombard, Carl“…In these trials, the educational programmes evaluated had no demonstrable effect on the prevalence of HIV (RR 1.03, 95% CI 0.80 to 1.32, three trials; 14,163 participants; low certainty evidence), or other STIs (herpes simplex virus prevalence: RR 1.04, 95% CI 0.94 to 1.15; three trials, 17,445 participants; moderate certainty evidence; syphilis prevalence: RR 0.81, 95% CI 0.47 to 1.39; one trial, 6977 participants; low certainty evidence). …”
Publicado 2016
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174023por Platt, Lucy, Minozzi, Silvia, Reed, Jennifer, Vickerman, Peter, Hagan, Holly, French, Clare, Jordan, Ashly, Degenhardt, Louisa, Hope, Vivian, Hutchinson, Sharon, Maher, Lisa, Palmateer, Norah, Taylor, Avril, Bruneau, Julie, Hickman, Matthew“…Overall, we found very low‐quality evidence that high NSP coverage did not reduce risk of HCV acquisition (RR 0.79, 95% CI 0.39 to 1.61) with high heterogeneity (I(2) = 77%) based on five studies from North America and Europe involving 3530 participants. …”
Publicado 2017
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174024por Gamble, Sonya, Mawokomatanda, Tebitha, Xu, Fang, Chowdhury, Pranesh P., Pierannunzi, Carol, Flegel, David, Garvin, William, Town, Machell“…Adults with high blood cholesterol: 28.8%–38.4% in states and territories and 26.3%–39.6% in MMSA. The following are estimates for 2014. …”
Publicado 2017
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174025por Leclercq, Christophe, Sadoul, Nicolas, Mont, Lluis, Defaye, Pascal, Osca, Joaquim, Mouton, Elisabeth, Isnard, Richard, Habib, Gilbert, Zamorano, Jose, Derumeaux, Genevieve, Fernandez-Lozano, Ignacio, Dupuis, Jean-Marc, Rouleau, Frédéric, Tassin, Aude, Bordachar, Pierre, Clémenty, Jacques, Lafitte, Stephane, Ploux, Sylvan, Reant, Patricia, Ritter, Philippe, Defaye, Pascal, Jacon, Peggy, Mondesert, Blandine, Saunier, Carole, Vautrin, Estelle, Kacet, Salem, Guedon-Moreau, Laurence, Klug, Didier, Kouakam, Claude, Marechaux, Sylvestre, Marquie, Christelle, Polge, Anne Sophie, Richardson, Marjorie, Chevallier, Philippe, De Breyne, Brigitte, Lotek, Marcin M., Nonin, Emilie, Pineau, Julien, Deharo, Jean-Claude, Bastard, Emilie, Franceschi, Frédéric, Habib, Gilbert, Jego, Christophe, Peyrouse, Eric, Prevot, Sebastien, Saint-Joseph, Hôpital, Bremondy, Michel, Faure, Jacques, Ferracci, Ange, Lefevre, Jean, Pisapia, Andre, Davy, Jean-Marc, Cransac, Frederic, Cung, Tien Tri, Georger, Frederic, Pasquie, Jean-Luc, Raczka, Franck, Sportouch-Dukhan, Catherine, Sadoul, Nicolas, Blangy, Hugues, Bruntz, Jean-François, Freysz, Luc, Groben, Laurent, Huttin, Olivier, Bammert, Antoine, Burban, Marc, Cebron, Jean-Pierre, Gras, Daniel, Frank, Robert, Duthoit, Guillaume, Hidden-Lucet, Françoise, Himbert, Caroline, Isnard, Richard, Lacotte, Jérôme, Pousset, Françoise, Zerah, Thierry, Leclercq, Christophe, Bellouin, Annaïk, Crocq, Christophe, Deplace, Christian, Donal, Erwan, Hamon, Cécile, Mabo, Philippe, Romain, Olivier, Solnon, Aude, Frederic, Anselme, Bauer, Fabrice, Bernard, Mathieu, Godin, Benedicte, Kurtz, Baptiste, Savoure, Arnaud, Copie, Xavier, Lascault, Gilles, Paziaud, Olivier, Piot, Olivier, Touche, Thierry, Delay, Toulouse Marc, Chilon, Talia, Detis, Nicolas, Duparc, Alexandre, Hebrard, Aurélien, Massabuau, Pierre, Maury, Philippe, Mondoly, Pierre, Rumeau, Philippe, Pasteur, Clinique, Boveda, Serge, Adrover, Laurence, Combes, Nicolas, Deplagne, Antoine, Marco-Baertich, Isabelle, Fondard, Olivier, Martínez, Juan Gabriel, Ibañez Criado, José Luis, Ortuño, Diego, Mont, Lluis, Berruezo, Antonio, Eduard, Belu, Martín, Ana, Merschon, Franco M., Sitges, Marta, Tolosana, José María, Vidal, Bárbara, Hebron, H. Valle, i Mitjans, Angel Moya, Rodriguez, Oscar Alcalde, Rodriguez Palomares, José Fernando, Rivas, Nuria, Teixidó, Gisela, de Hierro, H. Puerta, Lozano, Ignacio Fernández, Ruiz Bautista, Maria Lorena, Castro, Victor, Cavero, Miguel Angel, Gutierrez, Carlos, Ros, Natalia, de la Victoria, H. Virgen, Alzueta Rodriguez, Francisco Javier, Cabrera, Fernando, Cordero, Alberto Barrera, Peña, José Luis, de Valme Sevilla, H., Gonzáles, Juan Lealdel Ojo, Garcia Medina, Mª Dolores, Jiménez, Ricardo Pavón, Villagomez, David, de la Salud Toledo, H. Virgen, Castellanos Martinez, Eduardo, Alcalá, Juan, Maicas, Carolina, Arias Palomares, Miguel Angel, Puchol, Alberto, Valencia, H. La Fé, OscaAsensi, Joaquim, Carmona, Anastasio Quesada, De Carranza, Mª José Sancho-Tello, De Ros, José Olagüe, Pareja, Enrique Castro, Pérez, Oscar Cano, Saez, Ana Osa, Hortega, H. Rio, Guilarte, Benito Herreros, Muñoz San Jose, Juan Francisco, Pérez Sanz, Teresa Myriam, Logeart, Damien, Gil, Maria Lopez, Leclercq, Christophe, Lozano, Ignacio Fernandez, de Hierro, H. Puerta, Derumeaux, Genevieve“…Left ventricular end-systolic volume (LVESV) reduction between baseline and 6 months was not different between the two groups (−25.3 ± 39.4 mL in RVS group vs. −29.3 ± 44.5 mL in RVA group, P = 0.79). …”
Publicado 2016
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174026Publicado 2018“…The 2-year malaria incidence rate in the ITT population was non-inferior for pyronaridine–artesunate versus artemether–lumefantrine (1·77, 95% CI 1·63–1·93 vs 1·87, 1·72–2·03; rate ratio [RR] 1·05, 95% CI 0·94–1·17); and versus artesunate–amodiaquine (1·39, 95% CI 1·22–1·59 vs 1·35, 1·18–1·54; RR 0·97, 0·87–1·07). …”
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174027por Liu, Di, Xu, Xinyan, Wen, Junmiao, Xie, Liyi, Zhang, Junhua, Shen, Yuxin, Jiang, Guoliang, Chen, Jiayan, Fan, Min“…These 306 DEGs also included network genes of the above pathways such as NUF2, CCNE2, NFIB, ETV5, KLF5, ATAD2, NDC80, and ZWINT. In addition, 39 individual DEGs demonstrated a minimum 2-fold copy number-associated expression change (median: 5.35, 95% CI: 4.53–16.98) and Pearson's correlation coefficient ≥ 0.6 (p < 0.05), of which PTP4A3 showed the highest correlation (CNV-FC = 21362.13; Pearson's correlation coefficient = 0.9983; p = 0.037). …”
Publicado 2018
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174028por Christensen, Deborah L., Braun, Kim Van Naarden, Baio, Jon, Bilder, Deborah, Charles, Jane, Constantino, John N., Daniels, Julie, Durkin, Maureen S., Fitzgerald, Robert T., Kurzius-Spencer, Margaret, Lee, Li-Ching, Pettygrove, Sydney, Robinson, Cordelia, Schulz, Eldon, Wells, Chris, Wingate, Martha S., Zahorodny, Walter, Yeargin-Allsopp, Marshalyn“…The percentage of children with an earliest known comprehensive evaluation by age 36 months was similar for boys and girls, but was higher for non-Hispanic white children (45%) compared with non-Hispanic black children (40%) and Hispanic children (39%). INTERPRETATION: Overall estimated ASD prevalence was 14.5 per 1,000 children aged 8 years in the ADDM Network sites in 2012. …”
Publicado 2018
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174029por Jackson, Graham H, Davies, Faith E, Pawlyn, Charlotte, Cairns, David A, Striha, Alina, Collett, Corinne, Hockaday, Anna, Jones, John R, Kishore, Bhuvan, Garg, Mamta, Williams, Cathy D, Karunanithi, Kamaraj, Lindsay, Jindriska, Jenner, Matthew W, Cook, Gordon, Russell, Nigel H, Kaiser, Martin F, Drayson, Mark T, Owen, Roger G, Gregory, Walter M, Morgan, Gareth J“…After a median follow-up of 31 months (IQR 18–50), median progression-free survival was 39 months (95% CI 36–42) with lenalidomide and 20 months (18–22) with observation (hazard ratio [HR] 0·46 [95% CI 0·41–0·53]; p<0·0001), and 3-year overall survival was 78·6% (95% Cl 75·6–81·6) in the lenalidomide group and 75·8% (72·4–79·2) in the observation group (HR 0·87 [95% CI 0·73–1·05]; p=0·15). …”
Publicado 2019
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174030por Chauhan, Ganesh, Adams, Hieab H.H., Satizabal, Claudia L., Bis, Joshua C., Teumer, Alexander, Sargurupremraj, Muralidharan, Hofer, Edith, Trompet, Stella, Hilal, Saima, Smith, Albert Vernon, Jian, Xueqiu, Malik, Rainer, Traylor, Matthew, Pulit, Sara L., Amouyel, Philippe, Mazoyer, Bernard, Zhu, Yi-Cheng, Kaffashian, Sara, Schilling, Sabrina, Beecham, Gary W., Montine, Thomas J., Schellenberg, Gerard D., Kjartansson, Olafur, Guðnason, Vilmundur, Knopman, David S., Griswold, Michael E., Windham, B. Gwen, Gottesman, Rebecca F., Mosley, Thomas H., Schmidt, Reinhold, Saba, Yasaman, Schmidt, Helena, Takeuchi, Fumihiko, Yamaguchi, Shuhei, Nabika, Toru, Kato, Norihiro, Rajan, Kumar B., Aggarwal, Neelum T., De Jager, Philip L., Evans, Denis A., Psaty, Bruce M., Rotter, Jerome I., Rice, Kenneth, Lopez, Oscar L., Liao, Jiemin, Chen, Christopher, Cheng, Ching-Yu, Wong, Tien Y., Ikram, Mohammad K., van der Lee, Sven J., Amin, Najaf, Chouraki, Vincent, DeStefano, Anita L., Aparicio, Hugo J., Romero, Jose R., Maillard, Pauline, DeCarli, Charles, Wardlaw, Joanna M., Hernández, Maria del C. Valdés, Luciano, Michelle, Liewald, David, Deary, Ian J., Starr, John M., Bastin, Mark E., Muñoz Maniega, Susana, Slagboom, P. Eline, Beekman, Marian, Deelen, Joris, Uh, Hae-Won, Lemmens, Robin, Brodaty, Henry, Wright, Margaret J., Ames, David, Boncoraglio, Giorgio B., Hopewell, Jemma C., Beecham, Ashley H., Blanton, Susan H., Wright, Clinton B., Sacco, Ralph L., Wen, Wei, Thalamuthu, Anbupalam, Armstrong, Nicola J., Chong, Elizabeth, Schofield, Peter R., Kwok, John B., van der Grond, Jeroen, Stott, David J., Ford, Ian, Jukema, J. Wouter, Vernooij, Meike W., Hofman, Albert, Uitterlinden, André G., van der Lugt, Aad, Wittfeld, Katharina, Grabe, Hans J., Hosten, Norbert, von Sarnowski, Bettina, Völker, Uwe, Levi, Christopher, Jimenez-Conde, Jordi, Sharma, Pankaj, Sudlow, Cathie L.M., Rosand, Jonathan, Woo, Daniel, Cole, John W., Meschia, James F., Slowik, Agnieszka, Thijs, Vincent, Lindgren, Arne, Melander, Olle, Grewal, Raji P., Rundek, Tatjana, Rexrode, Kathy, Rothwell, Peter M., Arnett, Donna K., Jern, Christina, Johnson, Julie A., Benavente, Oscar R., Wasssertheil-Smoller, Sylvia, Lee, Jin-Moo, Wong, Quenna, Mitchell, Braxton D., Rich, Stephen S., McArdle, Patrick F., Geerlings, Mirjam I., van der Graaf, Yolanda, de Bakker, Paul I.W., Asselbergs, Folkert W., Srikanth, Velandai, Thomson, Russell, McWhirter, Rebekah, Moran, Chris, Callisaya, Michele, Phan, Thanh, Rutten-Jacobs, Loes C.A., Bevan, Steve, Tzourio, Christophe, Mather, Karen A., Sachdev, Perminder S., van Duijn, Cornelia M., Worrall, Bradford B., Dichgans, Martin, Kittner, Steven J., Markus, Hugh S., Ikram, Mohammad A., Fornage, Myriam, Launer, Lenore J., Seshadri, Sudha, Longstreth, W.T., Debette, Stéphanie“…Age- and sex-adjusted associations with BI and SSBI were observed for BP traits (p value for BI, p([BI]) = 9.38 × 10(−25); p([SSBI]) = 5.23 × 10(−14) for hypertension), smoking (p([BI]) = 4.4 × 10(−10); p([SSBI]) = 1.2 × 10(−4)), diabetes (p([BI]) = 1.7 × 10(−8); p([SSBI]) = 2.8 × 10(−3)), previous cardiovascular disease (p([BI]) = 1.0 × 10(−18); p([SSBI]) = 2.3 × 10(−7)), stroke (p([BI]) = 3.9 × 10(−69); p([SSBI]) = 3.2 × 10(−24)), and MRI-defined white matter hyperintensity burden (p([BI]) = 1.43 × 10(−157); p([SSBI]) = 3.16 × 10(−106)), but not with body mass index or cholesterol. …”
Publicado 2019
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174031por Lledo, B, Ortiz, J A, Morales, R, García-Hernández, E, Ten, J, Bernabeu, A, Llácer, J, Bernabeu, R“…However, this did not reach statistical significance when we compared embryos with a number of variants lower or higher than two (39.15 versus 20.0, P = 0.188). Finally, a clear positive association between the mtDNA variants and copy number was reported when we compare embryos with or without heteroplasmy (0.0013 ± 0.0009 versus 0.0025 ± 0.0014, P < 0.001) and among different numbers of variants (0:0.0013 ± 0.0009, 1–2:0.0023 ± 0.0012, >2:0.0043 ± 0.0014, P < 0.05). …”
Publicado 2018
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174032por Davies, Andrew, Cummin, Thomas E, Barrans, Sharon, Maishman, Tom, Mamot, Christoph, Novak, Urban, Caddy, Josh, Stanton, Louise, Kazmi-Stokes, Shamim, McMillan, Andrew, Fields, Paul, Pocock, Christopher, Collins, Graham P, Stephens, Richard, Cucco, Francesco, Clipson, Alexandra, Sha, Chulin, Tooze, Reuben, Care, Matthew A, Griffiths, Gareth, Du, Ming-Qing, Westhead, David R, Burton, Catherine, Johnson, Peter W M“…The most common grade 3 or worse adverse event was haematological toxicity, reported in 178 (39·8%) of 447 patients given R-CHOP and 187 (42·1%) of 444 given RB-CHOP. …”
Publicado 2019
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174033por Leijdekkers, Jori A, Eijkemans, Marinus J C, van Tilborg, Theodora C, Oudshoorn, Simone C, van Golde, Ron J T, Hoek, Annemieke, Lambalk, Cornelis B, de Bruin, Jan Peter, Fleischer, Kathrin, Mochtar, Monique H, Kuchenbecker, Walter K H, Laven, Joop S E, Mol, Ben Willem J, Torrance, Helen L, Broekmans, Frank J M“…The CLBR of older unexpected poor (n = 41) and suboptimal responders (n = 102) was ~42% and ~54%, respectively, and of older expected poor responders (n = 126) ~39%. For comparison, the CLBR of younger (n = 164) and older (n = 78) normal responders with an adequate ovarian reserve was ~72% and ~58% over 18 months of treatment, respectively. …”
Publicado 2019
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174034por Wilson, Duncan, Ambler, Gareth, Lee, Keon-Joo, Lim, Jae-Sung, Shiozawa, Masayuki, Koga, Masatoshi, Li, Linxin, Lovelock, Caroline, Chabriat, Hugues, Hennerici, Michael, Wong, Yuen Kwun, Mak, Henry Ka Fung, Prats-Sánchez, Luis, Martínez-Domeño, Alejandro, Inamura, Shigeru, Yoshifuji, Kazuhisa, Arsava, Ethem Murat, Horstmann, Solveig, Purrucker, Jan, Lam, Bonnie Yin Ka, Wong, Adrian, Kim, Young Dae, Song, Tae-Jin, Schrooten, Maarten, Lemmens, Robin, Eppinger, Sebastian, Gattringer, Thomas, Uysal, Ender, Tanriverdi, Zeynep, Bornstein, Natan M, Assayag, Einor Ben, Hallevi, Hen, Tanaka, Jun, Hara, Hideo, Coutts, Shelagh B, Hert, Lisa, Polymeris, Alexandros, Seiffge, David J, Lyrer, Philippe, Algra, Ale, Kappelle, Jaap, Al-Shahi Salman, Rustam, Jäger, Hans R, Lip, Gregory Y H, Mattle, Heinrich P, Panos, Leonidas D, Mas, Jean-Louis, Legrand, Laurence, Karayiannis, Christopher, Phan, Thanh, Gunkel, Sarah, Christ, Nicolas, Abrigo, Jill, Leung, Thomas, Chu, Winnie, Chappell, Francesca, Makin, Stephen, Hayden, Derek, Williams, David J, Kooi, M Eline, van Dam-Nolen, Dianne H K, Barbato, Carmen, Browning, Simone, Wiegertjes, Kim, Tuladhar, Anil M, Maaijwee, Noortje, Guevarra, Christine, Yatawara, Chathuri, Mendyk, Anne-Marie, Delmaire, Christine, Köhler, Sebastian, van Oostenbrugge, Robert, Zhou, Ying, Xu, Chao, Hilal, Saima, Gyanwali, Bibek, Chen, Christopher, Lou, Min, Staals, Julie, Bordet, Régis, Kandiah, Nagaendran, de Leeuw, Frank-Erik, Simister, Robert, van der Lugt, Aad, Kelly, Peter J, Wardlaw, Joanna M, Soo, Yannie, Fluri, Felix, Srikanth, Velandai, Calvet, David, Jung, Simon, Kwa, Vincent I H, Engelter, Stefan T, Peters, Nils, Smith, Eric E, Yakushiji, Yusuke, Orken, Dilek Necioglu, Fazekas, Franz, Thijs, Vincent, Heo, Ji Hoe, Mok, Vincent, Veltkamp, Roland, Ay, Hakan, Imaizumi, Toshio, Gomez-Anson, Beatriz, Lau, Kui Kai, Jouvent, Eric, Rothwell, Peter M, Toyoda, Kazunori, Bae, Hee-Joon, Marti-Fabregas, Joan, Werring, David J“…However, irrespective of cerebral microbleed anatomical distribution or burden, the rate of ischaemic stroke exceeded that of intracranial haemorrhage (for ten or more cerebral microbleeds, 64 ischaemic strokes [95% CI 48–84] per 1000 patient-years vs 27 intracranial haemorrhages [17–41] per 1000 patient-years; and for ≥20 cerebral microbleeds, 73 ischaemic strokes [46–108] per 1000 patient-years vs 39 intracranial haemorrhages [21–67] per 1000 patient-years). …”
Publicado 2019
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174035“…She had extensive investigations that showed raised CRP (61mg/L), eGFR 39ml/min/1.73m2 , weak positive rheumatoid factor and cold agglutinins, equivocal Lupus anticoagulant, negative ANCA, clear urinalysis, bilateral chronic inflammatory change on chest xray and thrombi of digital arteries on Doppler ultrasound of hands. …”
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174036por Bhusal, Binita, Oleru, Kiona, Arikian, Veronica, Jaster, Ryan, Stranz, Marc, Lindhorst, Justin“…Results: The total number of unique patients was 39,567, and the average number of dispenses per unique patient was two. …”
Publicado 2019
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174037por Toda, Mitsuru, Williams, Sabrina R., Berkow, Elizabeth L., Farley, Monica M., Harrison, Lee H., Bonner, Lindsay, Marceaux, Kaytlynn M., Hollick, Rosemary, Zhang, Alexia Y., Schaffner, William, Lockhart, Shawn R., Jackson, Brendan R., Vallabhaneni, Snigdha“…Candida albicans accounted for 39% of cases, followed by Candida glabrata (28%) and Candida parapsilosis (15%). …”
Publicado 2019
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174038por Murdock, Mark H., Chang, Jordan T., Hussey, George S., Amankulor, Nduka M., Engh, Johnathan A., Badylak, Stephen F.“…In a separate survival study comparing PBS to UBM-SSF injections in the flank-resection model, all animals given PBS had to be sacrificed at 9, 11, and 11 days (n=3) whereas animals given UBM-SSF were sacrificed at 15, 24, and 39 days (n=3), indicating a moderate increase in survival due to the UBM-SSF. …”
Publicado 2018
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174039“…Seven edible plant species were also used as herbal medicines. We also recorded 39 species used for other purposes in Monpa daily life. …”
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174040por van Welie, N, Dreyer, K, van Rijswijk, J, Verhoeve, H R, Goddijn, M, Nap, A W, Smeenk, J M J, Traas, M A F, Rijnsaardt-Lukassen, H G M, van Dongen, A J C M, Bourdrez, P, de Bruin, J P, Sluijmer, A V, Gijsen, A P, van de Ven, P M, Lambalk, C B, Mijatovic, V, Mol, B W J“…The RCT was restricted to infertile ovulatory women, younger than 39 years of age and with a low risk for tubal pathology. …”
Publicado 2019
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