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  1. 56561
    por Bravo, Lulu, Smolenov, Igor, Han, Htay Htay, Li, Ping, Hosain, Romana, Rockhold, Frank, Clemens, Sue Ann Costa, Roa, Camilo, Borja-Tabora, Charissa, Quinsaat, Antoinette, Lopez, Pio, López-Medina, Eduardo, Brochado, Leonardo, Hernández, Eder A, Reynales, Humberto, Medina, Tatiana, Velasquez, Hector, Toloza, Leonardo Bautista, Rodriguez, Edith Johana, de Salazar, Dora Ines Molina, Rodríguez, Camilo A, Sprinz, Eduardo, Cerbino-Neto, José, Luz, Kleber Giovanni, Schwarzbold, Alexandre Vargas, Paiva, Maria Sanali, Carlos, Josefina, Montellano, May Emmeline B, de Los Reyes, Mari Rose A, Yu, Charles Y, Alberto, Edison R, Panaligan, Mario M, Salvani-Bautista, Milagros, Buntinx, Erik, Hites, Maya, Martinot, Jean-Benoit, Bhorat, Qasim E, Badat, Aysha, Baccarini, Carmen, Hu, Branda, Jurgens, Jaco, Engelbrecht, Jan, Ambrosino, Donna, Richmond, Peter, Siber, George, Liang, Joshua, Clemens, Ralf
    Publicado 2022
    “…METHODS: This ongoing phase 2 and 3 double-blind, placebo-controlled trial was done in adults aged 18 years and older who were in good health or with a stable chronic health condition, at 31 sites in five countries (Belgium, Brazil, Colombia, Philippines, and South Africa). The participants were randomly assigned 1:1 using a centralised internet randomisation system to receive two 0·5 mL intramuscular doses of SCB-2019 (30 μg, adjuvanted with 1·50 mg CpG-1018 and 0·75 mg alum) or placebo (0·9% sodium chloride for injection supplied in 10 mL ampoules) 21 days apart. …”
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    Efficacy of the adjuvanted subunit protein COVID-19 vaccine, SCB-2019: a phase 2 and 3 multicentre, double-blind, randomised, placebo-controlled trial
  2. 56562
    “…Of these, sub‐Saharan Africa, Europe, and Asia contributed 16, three, and one evaluation respectively. …”
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    Point‐of‐care viral load tests to detect high HIV viral load in people living with HIV/AIDS attending health facilities
  3. 56563
    “…Specifically, 23 were on-line, 12 used telephone, 1 in-person, 1 through mail, and 1 used both on-line and telephone. 6 studies were based in North America while the remaining studies originated from across the globe (1 from Africa, 1 from Australia, 22 from Europe, 3 from Asia, 3 from South America, and 2 from a global sample). …”
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    The Impact of the COVID-19 Pandemic on the Mental Health of Older Adults
  4. 56564
    por Rimmer, Michael P, Howie, Ruth A, Anderson, Richard A, Barratt, Christopher L R, Barnhart, Kurt T, Beebeejaun, Yusuf, Bertolla, Ricardo Pimenta, Bhattacharya, Siladitya, Björndahl, Lars, Bortoletto, Pietro, Brannigan, Robert E, Cantineau, Astrid E P, Caroppo, Ettore, Collura, Barbara L, Coward, Kevin, Eisenberg, Michael L, De Geyter, Christian, Goulis, Dimitrios G, Henkel, Ralf R, Ho, Vu N A, Hussein, Alayman F, Huyser, Carin, Kadijk, Jozef H, Kamath, Mohan S, Khashaba, Shadi, Kobori, Yoshitomo, Kopeika, Julia, Kucuk, Tansu, Luján, Saturnino, Matsaseng, Thabo Christopher, Mathur, Raj S, McEleny, Kevin, Mitchell, Rod T, Mol, Ben W, Murage, Alfred M, Ng, Ernest H Y, Pacey, Allan, Perheentupa, Antti H, Du Plessis, Stefan, Rives, Nathalie, Sarris, Ippokratis, Schlegel, Peter N, Shabbir, Majid, Śmiechowski, Maciej, Subramanian, Venkatesh, Sunkara, Sesh K, Tarlarzis, Basil C, Tüttelmann, Frank, Vail, Andy, van Wely, Madelon, Vazquez-Levin, Mónica H, Vuong, Lan N, Wang, Alex Y, Wang, Rui, Zini, Armand, Farquhar, Cindy M, Niederberger, Craig, Duffy, James M N
    Publicado 2022
    “…Attendance at Fertility 2020 and Roadshow South Africa by Ralf Henkel was funded by LogixX Pharma Ltd. …”
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    Protocol for developing a core outcome set for male infertility research: an international consensus development study
  5. 56565
    Publicado 2022
    “…Between the start of the pandemic and Nov 14, 2021, there were an estimated 3·80 billion (95% uncertainty interval 3·44–4·08) total SARS-CoV-2 infections and reinfections combined, and an estimated 3·39 billion (3·08–3·63) individuals, or 43·9% (39·9–46·9) of the global population, had been infected one or more times. 1·34 billion (1·20–1·49) of these infections occurred in south Asia, the highest among the seven super-regions, although the sub-Saharan Africa super-region had the highest infection rate (79·3 per 100 population [69·0–86·4]). …”
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    Estimating global, regional, and national daily and cumulative infections with SARS-CoV-2 through Nov 14, 2021: a statistical analysis
  6. 56566
    “…Neonatal administration of the RV3-BB vaccine has the potential to improve protection against rotavirus disease in children in a high-child mortality country in Africa. FUNDING: Bill & Melinda Gates Foundation, Australian Tropical Medicine Commercialisation Grant.…”
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    Neonatal rotavirus vaccine (RV3-BB) immunogenicity and safety in a neonatal and infant administration schedule in Malawi: a randomised, double-blind, four-arm parallel group dose-ranging study
  7. 56567
    por Chan, Koon-Wing, Wong, Chung-Yin, Leung, Daniel, Yang, Xingtian, Fok, Susanna F. S., Mak, Priscilla H. S., Yao, Lei, Ma, Wen, Mao, Huawei, Zhao, Xiaodong, Liang, Weiling, Singh, Surjit, Barbouche, Mohamed-Ridha, He, Jian-Xin, Jiang, Li-Ping, Liew, Woei-Kang, Le, Minh Huong Thi, Muktiarti, Dina, Santos-Ocampo, Fatima Johanna, Djidjik, Reda, Belaid, Brahim, Ismail, Intan Hakimah, Abdul Latiff, Amir Hamzah, Lee, Way Seah, Chen, Tong-Xin, Liu, Jinrong, Jin, Runming, Wang, Xiaochuan, Chien, Yin Hsiu, Yu, Hsin-Hui, Raj, Dinesh, Raj, Revathi, Vaughan, Jenifer, Urban, Michael, van den Berg, Sylvia, Eley, Brian, Lee, Anselm Chi-Wai, Isa, Mas Suhaila, Ang, Elizabeth Y., Lee, Bee Wah, Yeoh, Allen Eng Juh, Shek, Lynette P., Quynh Le, Nguyen Ngoc, Nguyen, Van Anh Thi, Phan Nguyen Lien, Anh, Capulong, Regina D., Mallillin, Joanne Michelle, Villanueva, Jose Carlo Miguel M., Camonayan, Karol Anne B., Vera, Michelle De, Casis-Hao, Roxanne J., Lobo, Rommel Crisenio M., Foronda, Ruby, Binas, Vicky Wee Eng, Boushaki, Soraya, Kechout, Nadia, Phongsamart, Gun, Wongwaree, Siriporn, Jiratchaya, Chamnanrua, Lao-Araya, Mongkol, Trakultivakorn, Muthita, Suratannon, Narissara, Jirapongsananuruk, Orathai, Chantveerawong, Teerapol, Kamchaisatian, Wasu, Chan, Lee Lee, Koh, Mia Tuang, Wong, Ke Juin, Fong, Siew Moy, Thong, Meow-Keong, Latiff, Zarina Abdul, Noh, Lokman Mohd, de Silva, Rajiva, Jouhadi, Zineb, Al-Saad, Khulood, Vignesh, Pandiarajan, Jindal, Ankur Kumar, Rawat, Amit, Gupta, Anju, Suri, Deepti, Yang, Jing, Au, Elaine Yuen-Ling, Kwok, Janette Siu-Yin, Chan, Siu-Yuen, Hui, Wayland Yuk-Fun, Chua, Gilbert T., Duque, Jaime Rosa, Cheong, Kai-Ning, Chong, Patrick Chun Yin, Ho, Marco Hok Kung, Lee, Tsz-Leung, Wong, Wilfred Hing-Sang, Yang, Wanling, Lee, Pamela P., Tu, Wenwei, Yang, Xi-Qiang, Lau, Yu Lung
    Publicado 2022
    “…We also started to use whole exome sequencing (WES) for undiagnosed cases and further extended our collaboration with centres from South Asia and Africa. With the increased use of Next Generation Sequencing (NGS), we have shifted our diagnostic practice from SS to WES. …”
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    Targeted Gene Sanger Sequencing Should Remain the First-Tier Genetic Test for Children Suspected to Have the Five Common X-Linked Inborn Errors of Immunity
  8. 56568
    “…During April 4–18, we detected an increasing trend of pool positivity among travelers on South African flights, detecting one of the first US-reported BA.4 sub-lineages consistent with early surge of cases in South Africa. Weekly pooled positivity for travelers on South African flights aligned with World Health Organization (WHO)-reported 7-day COVID-19 incidence rates over the same period (Figure 3). …”
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    1525. The Impact of Traveler-Based Genomic Surveillance on SARS-CoV-2 Variant Detection in Arriving International Air Travelers– United States, November 29, 2021-April 24, 2022
  9. 56569
    “…AIMS/HYPOTHESIS: In sub-Saharan Africa (SSA), 5% of adults are living with type 2 diabetes and this is rising sharply, with a greater increase among people with HIV. …”
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    Metformin for the prevention of diabetes among people with HIV and either impaired fasting glucose or impaired glucose tolerance (prediabetes) in Tanzania: a Phase II randomised placebo-controlled trial
  10. 56570
    “…BACKGROUND: The double burden of malnutrition (DBM) is rising globally, particularly in sub-Saharan Africa. In Sierra Leone, the incidence of overweight, obesity (OWOB), and overnutrition among women has sharply increased. …”
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    Double burden of malnutrition among women in reproductive Age (15–49 years) in Sierra Leone: a secondary data analysis of the demographic health survey 2019 (SLDHS-2019)
  11. 56571
    “…Between 1990 and 2007, 15 southern white (Ceratotherium simum simum) and black (Diceros bicornis) rhinoceroses on average were killed illegally every year in South Africa. Since 2007 illegal killing of southern white rhinoceros for their horn has escalated to >950 individuals/year in 2013. …”
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    Identification of policies for a sustainable legal trade in rhinoceros horn based on population projection and socioeconomic models
  12. 56572
    “…However, six of these eight trials were from Asian settings, with only single trials from South America and sub‐Saharan Africa. In six trials, soap was provided free alongside hand washing education, and the overall average effect size was larger than in the two trials which did not provide soap (soap provided: rate ratio 0.66, 95% CI 0.56 to 0.78; six trials, 11,422 participants; education only: rate ratio: 0.84, 95% CI 0.67 to 1.05; two trials, 3304 participants). …”
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    Hand washing promotion for preventing diarrhoea
  13. 56573
    “…Seven trials were conducted in sub‐Saharan Africa and one in Thailand. Antihelminthics for people with unknown helminth infection status Providing antihelminthics (albendazole and praziquantel together or separately) to HIV‐positive adults with unknown helminth infection status may have a small suppressive effect on mean viral load at six weeks but the 95% CI includes the possibility of no effect (difference in mean change −0.14 log(10) viral RNA/mL, 95% CI −0.35 to 0.07, P = 0.19; one trial, 166 participants, low quality evidence). …”
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    Antihelminthics in helminth‐endemic areas: effects on HIV disease progression
  14. 56574
    “…All six included studies targeted private for‐profit pharmacy workers in Africa and Asia. Three studies found that training probably increases sale of oral rehydration solution (one trial in Kenya, 106 pharmacies: RR 3.04, 95% CI 1.37 to 6.75; and one trial in Indonesia, 87 pharmacies: RR 1.41, 95% CI 1.03 to 1.93) and dispensing of anti‐malarial drugs (one trial in Kenya, 293 pharmacies: RR 8.76, 95% CI 0.94 to 81.81); moderate‐certainty evidence. …”
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    Public stewardship of private for‐profit healthcare providers in low‐ and middle‐income countries
  15. 56575
    “…We tested the effect of rVSV-ZEBOV in preventing Ebola virus disease in contacts and contacts of contacts of recently confirmed cases in Guinea, west Africa. METHODS: We did an open-label, cluster-randomised ring vaccination trial (Ebola ça Suffit!) …”
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    Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)
  16. 56576
    “…Most included studies were from Asia, with five studies from sub‐Saharan Africa. All of the RDTs were designed to detect S.Typhi infection only. …”
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    Rapid diagnostic tests for typhoid and paratyphoid (enteric) fever
  17. 56577
    “…The included studies took place in Africa, Asia, and Latin America. Our synthesis pointed to a number of factors affecting SBAs’ provision of quality care. …”
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    Factors that influence the provision of intrapartum and postnatal care by skilled birth attendants in low‐ and middle‐income countries: a qualitative evidence synthesis
  18. 56578
    Publicado 2018
    “…The pace of progress achieved between 1990 and 2016 varied, with markedly faster improvements occurring between 2000 and 2016 for many countries in sub-Saharan Africa and southeast Asia, whereas several countries in Latin America and elsewhere saw progress stagnate after experiencing considerable advances in the HAQ Index between 1990 and 2000. …”
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    Measuring performance on the Healthcare Access and Quality Index for 195 countries and territories and selected subnational locations: a systematic analysis from the Global Burden of Disease Study 2016
  19. 56579
    “…The Global Enteric Multicenter Study (GEMS) has described the incidence, aetiology, and sequelae of medically attended moderate-to-severe diarrhoea (MSD) among children aged 0–59 months residing in censused populations in sub-Saharan Africa and south Asia, where most child deaths occur. …”
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    The incidence, aetiology, and adverse clinical consequences of less severe diarrhoeal episodes among infants and children residing in low-income and middle-income countries: a 12-month case-control study as a follow-on to the Global Enteric Multicenter Study (GEMS)
  20. 56580
    “…To date the course has reported the following analytics: (1) 2308 learners have visited the course page, (a)476 learners have enrolled in the course; (b) 244 learners are currently active in the course; (c) 11 learners have completed all of the requirements of the course. (2)Learners by Continent, (a) North America 31%; (b) Asia 30%; (c) Europe 23%; (d) Africa 9%;(e) South America 5%; (f) Oceania 2%. (2) Learners by Country: Learners have come from 84 different countries from around the world. …”
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    2358 Expanding our educational reach: Development of a massive open online course (MOOC)
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