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Optica
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1901“…DIAGNOSIS: We found no evidence for diagnoses of sarcoidosis, Behçet disease, multiple sclerosis, or neuromyelitis optica spectrum disorder. The CSF analysis revealed an elevation of the total protein concentration and that the patient was positive for VZV DNA, while anti-VZV IgG was not elevated. …”
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1902por Yeo, Tianrong, Probert, Fay, Jurynczyk, Maciej, Sealey, Megan, Cavey, Ana, Claridge, Timothy D.W., Woodhall, Mark, Waters, Patrick, Leite, Maria Isabel, Anthony, Daniel C., Palace, Jacqueline“…OBJECTIVE: To determine whether unsupervised principal component analysis (PCA) of comprehensive clinico-radiologic data can identify phenotypic subgroups within antibody-negative patients with overlapping features of multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSDs), and to validate the phenotypic classifications using high-resolution nuclear magnetic resonance (NMR) plasma metabolomics with inference to underlying pathologies. …”
Publicado 2019
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1903por Sharrack, Basil, Saccardi, Riccardo, Alexander, Tobias, Badoglio, Manuela, Burman, Joachim, Farge, Dominique, Greco, Raffaella, Jessop, Helen, Kazmi, Majid, Kirgizov, Kirill, Labopin, Myriam, Mancardi, Gianluigi, Martin, Roland, Moore, John, Muraro, Paolo A., Rovira, Montserrat, Sormani, Maria Pia, Snowden, John A.“…The major focus is on autologous HSCT (aHSCT), used in MS for over two decades and currently the fastest growing indication for this treatment in Europe, with increasing evidence to support its use in highly active relapsing remitting MS failing to respond to disease modifying therapies. aHSCT may have a potential role in the treatment of the progressive forms of MS with a significant inflammatory component and other immune-mediated neurological diseases, including chronic inflammatory demyelinating polyneuropathy, neuromyelitis optica, myasthenia gravis and stiff person syndrome. …”
Publicado 2019
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1904por Kim, Hyunjin, Lee, Eun-Jae, Kim, Seungmi, Choi, Lyn-Kyung, Kim, Keonwoo, Kim, Hye Weon, Kim, Kwang-Kuk, Lim, Young-Min“…OBJECTIVE: To test the hypothesis that the pattern of serum biomarkers of disease activity and disability in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) will be different from those in neuromyelitis optica spectrum disorder (NMOSD) with anti–aquaporin-4 antibodies (AQP4-Abs). …”
Publicado 2020
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1905por Bruijstens, Arlette L., Wong, Yu Yi M., van Pelt, Daniëlle E., van der Linden, Pieter J.E., Haasnoot, Geert W., Hintzen, Rogier Q., Claas, Frans H.J., Neuteboom, Rinze F., Wokke, Beatrijs H.A.“…OBJECTIVE: To investigate the possible human leukocyte antigen (HLA) association of both myelin oligodendrocyte glycoprotein (MOG-IgG)-associated diseases (MOGAD) and aquaporin-4 antibody (AQP4-IgG)-positive neuromyelitis optica spectrum disorders (NMOSDs) in the Dutch population with European ancestry to clarify similarities or differences in the immunogenetic background of both diseases. …”
Publicado 2020
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1906“…Previously an enigmatic partner to Multiple Sclerosis, Neuromyelitis Optica is now established to be autoimmune and two antibodies – to Aquaporin4 and to Myelin Oligodendrocyte Glycoprotein – have been implicated in the pathogenesis. …”
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1907por Yoo, Il Han, Kim, WooJoong, Shim, Youngkyu, Choi, Sun Ah, Kim, Soo Yeon, Kim, Hunmin, Lim, Byung Chan, Hwang, Hee, Choi, Jieun, Kim, Ki Joong, Kim, Yeseul, Hyun, Jae-Won, Kim, Su-Hyun, Choi, Kyungho, Kim, Ho Jin, Chae, Jong-Hee“…Acute disseminated encephalomyelitis (ADEM) (35.4%) was the most-common diagnosis, followed by the unclassified form (17.4%), isolated optic neuritis (ON) (15.2%), neuromyelitis optica spectrum disorder (13.0%), multiple sclerosis (MS) (10.8%), other clinically isolated syndromes [monophasic event except ADEM, isolated ON, or transverse myelitis (TM)] (8.7%), and unexplained encephalitis (4.3%). …”
Publicado 2020
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1908por Cui, Chunping, Tan, Sha, Tao, Li, Gong, Junli, Chang, Yanyu, Wang, Yuge, Fan, Ping, He, Dan, Ruan, Yiwen, Qiu, Wei“…BACKGROUND AND PURPOSE: The mechanism underlying the pathology of neuromyelitis optica spectrum disorders (NMOSD) remains unclear even though antibodies to the water channel protein aquaporin-4 (AQP4) on astrocytes play important roles. …”
Publicado 2020
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1909por Vanikieti, Kavin, Janyaprasert, Pavarut, Lueangram, Sirin, Nimworaphan, Jirat, Rattanathamsakul, Natthapon, Tiraset, Nanida, Chokthaweesak, Wimonwan, Samipak, Narong, Padungkiatsagul, Tanyatuth, Preechawat, Pisit, Poonyathalang, Anuchit, Pulkes, Teeratorn, Tunlayadechanont, Supoch, Siriyotha, Sukanya, Jindahra, Panitha“…The most common type of acute ON was idiopathic (51.5%), followed by neuromyelitis optica spectrum disorder (NMOSD, 30.9%), other autoimmune disorders (9.9%), myelin oligodendrocyte glycoprotein antibody-associated disorder (MOGAD, 5.3%), multiple sclerosis (MS, 1.8%), and postinfection (0.6%). …”
Publicado 2020
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1910por Chang, Sheng-Hui, Tian, Xiao-Bing, Wang, Jing, Liu, Ming-Qi, Huang, Chen-Na, Qi, Yuan, Zhang, Lin-Jie, Gao, Chun-Li, Zhang, Da-Qi, Sun, Li-Sha, Yang, Li“…Changes in serum and cerebrospinal fluid (CSF) levels of UA have been reported in patients with multiple sclerosis and neuromyelitis optica spectrum disorders. The levels of UA in CSF are relatively poorly understood in patients with Guillain–Barré syndrome (GBS). …”
Publicado 2020
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1911“…Others (4%) were not in ASFA indications. Neuromyelitis optica spectrum disorders accounted for half (51%) of the total patients. …”
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1912por Cubas-Núñez, Laura, Gil-Perotín, Sara, Castillo-Villalba, Jéssica, López, Verónica, Solís Tarazona, Luis, Gasqué-Rubio, Raquel, Carratalá-Boscá, Sara, Alcalá-Vicente, Carmen, Pérez-Miralles, Francisco, Lassmann, Hans, Casanova, Bonaventura“…METHODS: NfL and CHI3L1 in CSF and serum CHI3L1 were assessed retrospectively in a cross-sectional cohort of controls (n = 17) and patients diagnosed with MS (n = 224), relapsing (n = 163) or progressive (n = 61); neuromyelitis optica (NMO, n = 7); and acute disseminated encephalomyelitis (ADEM, n = 15). …”
Publicado 2021
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1913“…CASE REPORT: The recipient was a 28-year old female with past medical history of neuromyelitis optica treated with mycophenolate and rituximab who developed COVID pneumonia leading acute respiratory distress syndrome. …”
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1914por Ostendorf, Lennard, Dittert, Philipp, Biesen, Robert, Duchow, Ankelien, Stiglbauer, Victoria, Ruprecht, Klemens, Bellmann-Strobl, Judith, Seelow, Dominik, Stenzel, Werner, Niesner, Raluca A., Hauser, Anja E., Paul, Friedemann, Radbruch, Helena“…We aimed to evaluate SIGLEC1 (CD169) as a biomarker in multiple sclerosis (MS) and Neuromyelitis optica spectrum disorder (NMOSD) and to evaluate the presence of SIGLEC1(+) myeloid cells in demyelinating diseases. …”
Publicado 2021
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1915por Sriwastava, Shitiz, Tandon, Medha, Podury, Sanjiti, Prasad, Apoorv, Wen, Sijin, Guthrie, Garret, Kakara, Mihir, Jaiswal, Shruti, Subedi, Roshan, Elkhooly, Mahmoud, Lisak, Robert P.“…METHODS: We screened all articles resulting from a search of PubMed, Google Scholar and Scopus, using the keywords; “SARS-CoV-2 and neurological complication”, “SARS-CoV-2 and CNS Complication” looking for reports of transverse myelitis, longitudinally extensive transverse myelitis, neuromyelitis optica, myelitis, Myelin Oligodendrocyte Glycoprotein Antibody Disorder (MOGAD), Acute Disseminated Encephalomyelitis (ADEM), Acute Hemorrhagic Necrotizing Encephalitis/Acute Hemorrhagic Leukoencephalitis (AHNE/AHLE), Cytotoxic lesion of the Corpus Callosum/Mild Encephalopathy Reversible Splenium Lesion(CLOCC/MERS) and Optic neuritis published between December 01, 2019 and March 15, 2021. …”
Publicado 2021
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1916por Duan, Yunyun, Zhuo, Zhizheng, Li, Haiqing, Tian, De-Cai, Li, Yuxin, Yang, Liqin, Gao, Chenyang, Zhang, Tian, Zhang, Xinghu, Shi, Fu-Dong, Barkhof, Frederik, Liu, Yaou“…METHODS: We recruited 35 MOGAD, 38 aquaporin 4 antibody positive neuromyelitis optica spectrum diseases (AQP4+ NMOSD), 37 multiple sclerosis (MS) and 60 healthy controls (HC) who underwent multimodal brain MRI from two centres. …”
Publicado 2021
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1917“…BACKGROUND: The COVID-19 vaccines are currently recommended for people with rare neuroimmunological diseases such as neuromyelitis optica spectrum disorder (NMOSD), MOG-antibody disease (MOGAD), and transverse myelitis. …”
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1918por Contentti, Edgar Carnero, Lopez, Pablo A, Pettinicchi, Juan Pablo, Criniti, Juan, Pappolla, Agustín, Miguez, Jimena, Patrucco, Liliana, Carnero Contentti, Edgardo, Liwacki, Susana, Tkachuk, Verónica, Balbuena, María E, Vrech, Carlos, Deri, Norma, Correale, Jorge, Marrodan, Mariano, Ysrraelit, María C, Leguizamon, Felisa, Luetic, Geraldine, Menichini, María L, Tavolini, Darío, Mainella, Carolina, Zanga, Gisela, Burgos, Marcos, Hryb, Javier, Barboza, Andrés, Lazaro, Luciana, Alonso, Ricardo, Liguori, Nora Fernández, Nadur, Débora, Chercoff, Aníbal, Alonso Serena, Marina, Caride, Alejandro, Paul, Friedemann, Rojas, Juan I“…We aimed to examine treatment interventions implemented in patients experiencing neuromyelitis optica spectrum disorders (NMOSD) attacks (frequency, types, and response). …”
Publicado 2021
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1919por Ali, Ahya, Dwyer, Deanna, Wu, Qi, Wang, Qin, Dowling, Catherine A., Fox, David A., Khanna, Dinesh, Poland, Gregory A., Mao-Draayer, Yang“…Little is known about COVID-19 mRNA vaccine humoral immune responses in patients with central nervous system autoimmune demyelinating diseases, multiple sclerosis (MS) and neuromyelitis optica (NMO), who are on B-cell depleting therapies (BCDT) and other disease modifying therapies (DMTs). …”
Publicado 2021
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1920“…It has several varied causes out of which neuromyelitis optica (NMO) and its spectrum disorder have received a distinct entity. …”
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