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  1. 57541
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    Reduction of unwanted submental fat with ATX-101 (deoxycholic acid), an adipocytolytic injectable treatment: results from a phase III, randomized, placebo-controlled study
  2. 57542
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    Report from the third international consensus meeting to harmonise core outcome measures for atopic eczema/dermatitis clinical trials (HOME)
  3. 57543
    “…Our results indicated that there might be cross-talk between the Xa39-mediated signal transduction cascades and the GA/BR signaling pathway, and that the defense mechanism was related to diverse kinases, transcription factors, post-translational regulation, and R genes. …”
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    Comparative transcriptome profiling of a rice line carrying Xa39 and its parents triggered by Xanthomonas oryzae pv. oryzae provides novel insights into the broad-spectrum hypersensitive response
  4. 57544
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    Nationwide bowel cancer screening programme in England: cohort study of lifestyle factors affecting participation and outcomes in women
  5. 57545
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    Microsatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis
  6. 57546
    “…Disability level, HRQL and impact of fatigue were assessed using the Expanded Disability Status Scale (EDSS) and the Brazilian versions of EQ-5D-3L and Modified Fatigue Impact Scale (MFIS-BR), respectively. Patients were classified in subgroups according to EDSS (mild: 0–3; moderate: 4–6.5; severe: >7) and the self-perceived impact of fatigue (absent: ≤38 points; low: 39–58; high: ≥59). …”
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    Differences in utility scores obtained through Brazilian and UK value sets: a cross-sectional study
  7. 57547
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    Obesity and survival among women with ovarian cancer: results from the Ovarian Cancer Association Consortium
  8. 57548
    “…Proliferation of the cells was assessed by WST-1 assays and cell cycle status was measured by flow-cytometry after BrDU/7-AAD staining. The effect of IGFBP7 over-expression on sensitivity to cytostatic drugs was determined in AnnexinV/7-AAD assays. …”
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    Inhibition of IGF1-R overcomes IGFBP7-induced chemotherapy resistance in T-ALL
  9. 57549
    “…Because a number of medium strong electrophiles from a series of α-X-substituted 2’,3,4,4’-tetramethoxychalcones (α-X-TMCs, X = H, F, Cl, Br, I, CN, Me, p-NO(2)-C(6)H(4), Ph, p-OMe-C(6)H(4), NO(2), CF(3), COOEt, COOH) had proven to activate Nrf2 resulting in HO-1 induction and inhibit NF-κB downstream target genes, their protective effect against staurosporine induced apoptosis and reactive oxygen species (ROS) production was investigated. …”
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    The Cytoprotective Effects of E-α-(4-Methoxyphenyl)-2’,3,4,4'-Tetramethoxychalcone (E-α-p-OMe-C(6)H(4)-TMC)—A Novel and Non-Cytotoxic HO-1 Inducer
  10. 57550
    “…Individuals were classified as Higher Risk (population adjusted odds >2), Average Risk (between 0.5 and 2), and Lower Risk (<0.5) for each time point and we compared classifications between time points for breast cancer (BrCa), prostate cancer (PrCa), diabetes mellitus type 2 (T2D), and cardiovascular heart disease (CHD). …”
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    Reclassification of genetic-based risk predictions as GWAS data accumulate
  11. 57551
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    Chemotherapy vs supportive care alone for relapsed gastric, gastroesophageal junction, and oesophageal adenocarcinoma: a meta-analysis of patient-level data
  12. 57552
    por Garcia-Albeniz, Xabier, Rudolph, Anja, Hutter, Carolyn, White, Emily, Lin, Yi, Rosse, Stephanie A, Figueiredo, Jane C, Harrison, Tabitha A, Jiao, Shuo, Brenner, Hermann, Casey, Graham, Hudson, Thomas J, Thornquist, Mark, Le Marchand, Loic, Potter, John, Slattery, Martha L, Zanke, Brent, Baron, John A, Caan, Bette J, Chanock, Stephen J, Berndt, Sonja I, Stelling, Deanna, Fuchs, Charles S, Hoffmeister, Michael, Butterbach, Katja, Du, Mengmeng, James Gauderman, W, Gunter, Marc J, Lemire, Mathieu, Ogino, Shuji, Lin, Jennifer, Hayes, Richard B, Haile, Robert W, Schoen, Robert E, Warnick, Greg S, Jenkins, Mark A, Thibodeau, Stephen N, Schumacher, Fredrick R, Lindor, Noralane M, Kolonel, Laurence N, Hopper, John L, Gong, Jian, Seminara, Daniela, Pflugeisen, Bethann M, Ulrich, Cornelia M, Qu, Conghui, Duggan, David, Cotterchio, Michelle, Campbell, Peter T, Carlson, Christopher S, Newcomb, Polly A, Giovannucci, Edward, Hsu, Li, Chan, Andrew T, Peters, Ulrike, Chang-Claude, Jenny
    Publicado 2016
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    CYP24A1 variant modifies the association between use of oestrogen plus progestogen therapy and colorectal cancer risk
  13. 57553
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    Association between the HLA-DQB1 polymorphisms and the susceptibility of chronic hepatitis B: A comprehensive meta-analysis
  14. 57554
    “…The cells were treated with different doses of 1,25-(OH)(2)D(3) (0, 0.1, 1.0, 10.0 and 100.0 nmol/L) for calcium transport research, followed by a 3-bromopyruvate (3-BrPA, an inhibitor of glucose metabolism) treatment to determine its dependence on glucose availability. …”
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    1,25-Dihydroxyvitamin D(3) modulates calcium transport in goat mammary epithelial cells in a dose- and energy-dependent manner
  15. 57555
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    Prognostic role of ERBB2, MET and VEGFA expression in metastatic colorectal cancer patients treated with anti-EGFR antibodies
  16. 57556
    “…CSC-induced molecular changes were evaluated through cell viability using MTT assay, reactive oxygen species (ROS) measurement using 2,7 dichlorodihydrofluorescin diacetate (DCFH-DA), cell membrane integrity using fluorescein diacetate (FDA) and ethidium bromide (EtBr) staining, super oxide dismutase (SOD) levels, cPLA(2) activity and molecular involvement of specific cPLA(2)s at selected 24 h time period. …”
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    Cytosolic phospholipase A(2) (cPLA(2)) IVA as a potential signature molecule in cigarette smoke condensate induced pathologies in alveolar epithelial lineages
  17. 57557
    “…RESULTS: We cloned the E. coli bidirectional fepB/entC promoter region into low-copy-number plasmid backbones (pACYC184 and pBR322) along with downstream sequences encoding epitope tags and a multiple cloning site (MCS) compatible with the bacterial adenylate cyclase two-hybrid (BACTH) system. …”
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    A novel set of vectors for Fur-controlled protein expression under iron deprivation in Escherichia coli
  18. 57558
    por Andronis, L., Calvert, M., Magill, L., Mathers, J., Pinkney, T. D., Torrance, A., Talbot, H., Blazeby, J. M., Blencowe, N. S., Coast, J., Draycott, T., Donovan, J., Gooberman‐Hill, R., Reeves, B. C., Rogers, C. A., Longman, R., Woodward, M., Young, T., Bird, J., Clayton, G., Ellis, L., Macefield, R., Milne, T., van der Nelson, H., Nicholson, A., Rooshenas, L., Siassakos, D., Strong, S., Townsend, D., McMullan, C., Winter, C., Atherton, G., Tafazal, H., Eriksson, A., Chapman, T., Zafar, Z., Chang, J., Sharma, E., Green, N., Shariff, U., Neito, T., Youssef, H., Marriott, P., Popplewell, M., Ring, N., Sharples, A., Summerour, V., Bhangu, A., Upchurch, E., Hardy, T., Monteiro de Barros, J., Reza, L., Ekere, C., Greenwood, A., Strong, S., Florance, C., Orchard, P., Court, E., Ives, C., Papworth, E., Lee, C., Buchan, S., Bennett, J., Rowlands, C., Frank, L., Ide, K.‐A., Noble, E., Sellars, H., Anderson, E., Fallaize, R., Kynaston, J., Hotton, E., Banks, J., Thompson, N., Hodkinson, T., Blencowe, N., Bamford, R., Newman, P., Cutting, J., Barber, Z., Grant, C., Mason, J., Bailey, J.
    Publicado 2016
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    Feasibility work to inform the design of a randomized clinical trial of wound dressings in elective and unplanned abdominal surgery
  19. 57559
    “…Compared to the absence of phenylalanine-arginine-β-naphthylamide (PAβN), the fluorescence intensity of EtBr was increased in K. pneumoniae cells treated at the CON, CON-CIP, and CON-MER in the presence of PAβN. …”
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    Assessment of antibiotic resistance in Klebsiella pneumoniae exposed to sequential in vitro antibiotic treatments
  20. 57560
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    Trastuzumab-associated cardiac events in the Persephone trial
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