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  1. 57641
    “…We used the information available in two public databases (http://www.bipmed.org and http://abraom.ib.usp.br/) and additional exomes from individuals born in southeast Brazil, the region of the country with the highest number of COVID-19 patients. …”
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    Genetic variability in COVID-19-related genes in the Brazilian population
  2. 57642
    “…In the structure of ethyl (Z)-2-{2-[3′-methyl-1′-phenyl-5-(thio­phen-2-yl)-5′-(2-methyl­phen­oxy)-3,4-di­hydro-1′H,2H-3,4′-bi­pyrazole-2-yl]-4-oxo-4,5-di­hydro­thia­zol-5-yl­idene}acetate, C(31)H(27)N(5)O(4)S(2) (II), inversion-related pairs of mol­ecules are linked by paired C—H⋯π(arene) hydrogen bonds to form cyclic centrosymmetric dimers, but there are no direction-specific inter­molecular inter­actions in 4-(4-bromo­phen­yl)-2-[5′-(2,4-di­chloro­phen­oxy)-3′-methyl-1′-phenyl-5-(thio­phen-2-yl)-3,4-di­hydro-1′H,2H-3,4′-bi­pyrazole-2-yl]-4-thia­zole, C(32)H(22)BrCl(2)N(5)OS(2) (III). Comparisons are made with the structures of some related compounds.…”
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    Reduced 3,4′-bi­pyrazoles carrying thio­phene and thia­zole substituents: structures of two intermediates and two products
  3. 57643
    “…An open-source and free risk calculator was generated for clinical use and is available online at https://ufrgs.br/prodah/adhd-calculator/. CONCLUSIONS: The risk tool based on childhood characteristics specifically predicts adult ADHD in European and North-American population-based and clinical samples with comparable discrimination to commonly used clinical tools in internal medicine and higher than most previous attempts for mental and neurological disorders. …”
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    A risk calculator to predict adult attention-deficit/hyperactivity disorder: generation and external validation in three birth cohorts and one clinical sample
  4. 57644
    por McGrath, Mary, Smink, Gayle
    Publicado 2021
    “…Pediatric AML commonly has genetic rearrangements which involve chromosome 11q23 in 15–20% of cases, and these genetic abnormalities have been associated with a poorer prognosis (Grimwade et al. in Blood 92:2322–2333, 1998; Raimondi et al. in Blood 94:3707–3716, 1999; Lie et al. in Br J Haematol 122: 217–225). MLL rearrangements in AML have been shown to have multiple different fusion partners (Meyer et al. in Leukemia 23:1490–1499). …”
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    Double and single mixed-lineage leukemia-rearranged subclones in pediatric acute myeloid leukemia: a case report
  5. 57645
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    Effect of oxymatrine on liver gluconeogenesis is associated with the regulation of PEPCK and G6Pase expression and AKT phosphorylation
  6. 57646
    “…The expression of miR-768-3p in tumor tissues and adjacent tissues of 116 patients with breast cancer obtained by surgery and normal breast cell lines MCF-10A and breast cancer cell lines (MCF-7, MDA-MB-231, T-47D and SK-BR-3) were detected by reverse transcription-quantitative PCR. …”
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    Decreased microRNA-768-3p expression indicates a poor prognosis in patients with breast cancer and promotes breast cancer cell viability, migration and invasion
  7. 57647
    “…Pearl millet [Pennisetum glaucum (L.) R. Br.] is grown under both arid and semi-arid conditions in India, where other cereals are hard to grow. …”
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    Performance and Stability of Pearl Millet Varieties for Grain Yield and Micronutrients in Arid and Semi-Arid Regions of India
  8. 57648
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    A head‐to‐head comparison of ixekizumab vs. guselkumab in patients with moderate‐to‐severe plaque psoriasis: 24‐week efficacy and safety results from a randomized, double‐blinded trial
  9. 57649
    “…HRQoL was assessed using seven prespecified scores from the European Organisation for Research and Treatment of Cancer Quality Of Life Questionnaire core module (QLQ-C30) and breast cancer-specific questionnaire (QLQ-BR23) at baseline and every 6 weeks. Descriptive statistics summarized scores over time, mixed models evaluated differences between treatment arms, and Kaplan–Meier methods were used to assess time to deterioration in HRQoL scores of ≥ 10 points. …”
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    Neratinib + capecitabine sustains health-related quality of life in patients with HER2-positive metastatic breast cancer and ≥ 2 prior HER2-directed regimens
  10. 57650
    “…Parameters include cross-sectional area (CSA), cross-sectional moment of inertia (CSMI), subperiosteal width (SPW), endocortical width (ECW), cortical thickness (CT), section modulus (Z), and buckling ratio (BR)—each measured in the narrow neck (NN), intertrochanteric (IT), and femoral shaft (FS) regions. …”
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    Hip Geometry Variation in Homozygous Ectonucleotide Pyrophosphatase/ Phosphodiesterase 1 (ENPP1) Deficient Patients
  11. 57651
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    Bridging The Age Gap: observational cohort study of effects of chemotherapy and trastuzumab on recurrence, survival and quality of life in older women with early breast cancer
  12. 57652
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    New clinical and biological insights from the international TARGIT-A randomised trial of targeted intraoperative radiotherapy during lumpectomy for breast cancer
  13. 57653
    “…Validated EORTC QLQ-C30/BR23 questionnaires were used to asses HRQL. Multivariable linear regression models adjusted for confounding (age, comorbidity, pT, locoregional treatment, systemic therapy) were used to compare the impact of the RT regimens on HRQL at 12 and 24 months. …”
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    Health-related quality of life of early-stage breast cancer patients after different radiotherapy regimens
  14. 57654
    “…Registered in 23/07/2019 (retrospectively), http://www.ensaiosclinicos.gov.br/rg/RBR-5qkn8h/.…”
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    Effect of adding hydrochlorothiazide to usual treatment of patients with acute decompensated heart failure: a randomized clinical trial
  15. 57655
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    Risk of COVID-19 death in cancer patients: an analysis from Guy’s Cancer Centre and King’s College Hospital in London
  16. 57656
    “…RT-qPCR results of 12 breast cancer surgical specimens and SK-BR-3, MCF-7, and LD cell lines further confirmed the presence of the regulatory axis. …”
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    Knockdown of ALDH1A3 reduces breast cancer stem cell marker CD44 via the miR-7-TGFBR2-Smad3-CD44 regulatory axis
  17. 57657
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    Management of plantar heel pain: a best practice guide informed by a systematic review, expert clinical reasoning and patient values
  18. 57658
    “…Registered 07 February 2019—https://ensaiosclinicos.gov.br/trial/5970/1.…”
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    Effects of Non-periodized and Linear Periodized Combined Exercise Training on Insulin Resistance Indicators in Adults with Obesity: A Randomized Controlled Trial
  19. 57659
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    Insights into homeobox B9: a propeller for metastasis in dormant prostate cancer progenitor cells
  20. 57660
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    Prone positioning for non-intubated spontaneously breathing patients with acute hypoxaemic respiratory failure: a systematic review and meta-analysis
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