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37681por Casanova, Ludovic, Cortaredona, Sébastien, Gaudart, Jean, Launay, Odile, Vanhems, Philippe, Villani, Patrick, Verger, Pierre“…ETHICS AND DISSEMINATION: The study has been approved by the French Commission on Individual Data Protection and Public Liberties (ref: AT/CPZ/SVT/JB/DP/CR05222O). The study's findings will be published in peer-reviewed journals and disseminated at international conferences and through social media.…”
Publicado 2017
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37682por Roberts, Brock, Haupt, Amanda, Tucker, Andrew, Grancharova, Tanya, Arakaki, Joy, Fuqua, Margaret A., Nelson, Angelique, Hookway, Caroline, Ludmann, Susan A., Mueller, Irina A., Yang, Ruian, Horwitz, Rick, Rafelski, Susanne M., Gunawardane, Ruwanthi N.“…Our genome-editing methodology using Cas9/crRNA ribonuclear protein and donor plasmid coelectroporation, followed by fluorescence-based enrichment of edited cells, typically resulted in <0.1–4% homology-directed repair (HDR). …”
Publicado 2017
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37683“…Patients with higher expression of miR-148b showed a higher complete remission (CR) rate (p=0.043). Importantly, higher expression of miR-148a/b was correlated with lower relapse rate (p=0.035, p=0.027, respectively) and showed a longer relapse-free survival (RFS) (p=0.0321, p=0.002, respectively). …”
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37684por Sander, Frida Ewald, Nilsson, Malin, Rydström, Anna, Aurelius, Johan, Riise, Rebecca E., Movitz, Charlotta, Bernson, Elin, Kiffin, Roberta, Ståhlberg, Anders, Brune, Mats, Foà, Robin, Hellstrand, Kristoffer, Thorén, Fredrik B., Martner, Anna“…In a phase IV trial (Re:Mission Trial, NCT01347996, http://www.clinicaltrials.gov) 84 patients (age 18–79) with acute myeloid leukemia (AML) in first complete remission (CR) received ten consecutive 3-week cycles of immunotherapy with histamine dihydrochloride (HDC) and low-dose interleukin-2 (IL-2) to prevent relapse of leukemia in the post-consolidation phase. …”
Publicado 2017
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37685por Katsumata, Mari, Hirawa, Nobuhito, Sumida, Koichiro, Kagimoto, Minako, Ehara, Yosuke, Okuyama, Yuki, Fujita, Megumi, Fujiwara, Akira, Kobayashi, Mayumi, Kobayashi, Yusuke, Yamamoto, Yuichiro, Saka, Sanae, Yatsu, Keisuke, Fujikawa, Tetsuya, Toya, Yoshiyuki, Yasuda, Gen, Tamura, Kouichi, Umemura, Satoshi“…The urine osmolality significantly decreased throughout the study period. Urinary Na/Cr ratio and FENa changed significantly after 4 h, and more remarkable after 8 h (p = 0.003, both). …”
Publicado 2017
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37686por Vetter, Marcus, Fokas, Spyridon, Biskup, Ewelina, Schmid, Thomas, Schwab, Fabienne, Schoetzau, Andreas, Güth, Uwe, Rochlitz, Christoph, Zanetti-Dällenbach, Rosanna“…Adding platinum derivatives in the neo-adjuvant setting has been shown to not only improve the pCR rates, but also the 3 year DFS for TNBC patients; however, data on platinum derivatives in the adjuvant setting are limited. …”
Publicado 2017
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37687por Choi, Hyun Su, Hwang, Jeong Kye, Kim, Jeong Goo, Hwang, Hyeon Seok, Lee, Sang Ju, Chang, Yoon kyung, Kim, Ji Il, Moon, In Sung“…RESULTS: Results indicated that BUN and creatinine (Cr) levels increased significantly in the I/R group, but the elevations were significantly lower in IP groups, especially in the IP-5 group. …”
Publicado 2017
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37688por Zhang, Wen-ying, Wang, Yao, Guo, Ye-lei, Dai, Han-ren, Yang, Qing-ming, Zhang, Ya-jing, Zhang, Yan, Chen, Mei-xia, Wang, Chun-meng, Feng, Kai-chao, Li, Su-xia, Liu, Yang, Shi, Feng-xia, Luo, Can, Han, Wei-dong“…The median progression-free survival lasted for >6 months, and 1 patient had a 27-month continuous CR. A significant inverse correlation between the levels of the CAR gene and disease recurrence or progression was observed. …”
Publicado 2016
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37689
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37690por Fathala, Ahmed, Salem, Salma, Alanazi, Fahad, Abunayyan, Deema, Eldali, Abdelmoneim M., Alsugair, AbdulazizEnlace del recurso
Publicado 2017
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37691por Taquiso, Jezreel L., Obillos, Stephanie Martha O., Mojica, Joerelle V., Abrahan, Lauro L., Cunanan, Elleen C., Aherrera, Jaime Alfonso M., Magno, Jose Donato A.Enlace del recurso
Publicado 2017
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37692por Farina, Eleonora, Monari, Fabio, Castellucci, Paolo, Romani, Fabrizio, Repaci, Andrea, Farina, Arianna, Zanirato Rambaldi, Giuseppe, Frezza, Giovanni, Mazzarotto, Renzo, Cammelli, Silvia, Tagliaferri, Luca, Autorino, Rosa, Deodato, Francesco, Macchia, Gabriella, Cilla, Savino, Valentini, Vincenzo, Fanti, Stefano, Morganti, Alessio G.“…Post-EBRT (18)F-FDG PET/CT showed CR in 43.7%, PR in 31.2%, SD in 25.0% patients, and PD due to lung metastases in 12.5%. …”
Publicado 2017
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37693por Zou, Changsong, Chen, Aojun, Xiao, Lihong, Muller, Heike M, Ache, Peter, Haberer, Georg, Zhang, Meiling, Jia, Wei, Deng, Ping, Huang, Ru, Lang, Daniel, Li, Feng, Zhan, Dongliang, Wu, Xiangyun, Zhang, Hui, Bohm, Jennifer, Liu, Renyi, Shabala, Sergey, Hedrich, Rainer, Zhu, Jian-Kang, Zhang, HengEnlace del recurso
Publicado 2017
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37694“…RESULTS: At final pathology, residual microcalcifications were malignant in 55.2% of cases and benign in 44.8% of cases. In 36% of non-pCR cases, the remaining microcalcifications were benign. …”
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37695por Kim, Ji-Yeon, Park, Donghyun, Son, Dae-Soon, Nam, Seok Jin, Kim, Seok Won, Jung, Hae Hyun, Kim, Yeon Jeong, Park, Gahee, Park, Woong-Yang, Lee, Jeong Eon, Park, Yeon Hee“…With respect to the therapeutic effects of NAC, we found two samples in which ctDNA disappeared after the 1(st) NAC cycle achieved a pathologic complete response (pCR). In addition, the amount of ctDNA correlated with residual cancer volume detected by breast MRI. …”
Publicado 2017
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37696por Bocşan, Ioan Stelian, Brumboiu, Irina, Călinici, Tudor, Vlad, Mariana, Roman, Cecilia, Brie, Ioana, Ponta, Mihaela Lucia“…METHODS: Using a multidisciplinary approach throughout a complex epidemiological study, we investigated the potential oncogenic role of non-occupational environmental exposure to some heavy metals [chrome (Cr), nickel (Ni), copper (Cu), zinc (Zn), cadmium (Cd), lead (Pb) and arsenic (As)—in soil, drinking water, and food, as significant components of the environment] in populations living in areas with different environmental levels (high vs. low) of the above-mentioned heavy metals. …”
Publicado 2016
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37697por Scott, Alexander W., Zhou, Yifang, Allahverdian, Janet, Nute, Jessica L., Lee, Christina“…Peaks were observed at the current calibrated EI, a previously calibrated EI, and an EI representing computed radiography (CR) techniques. Our findings in this ongoing project have allowed us to make useful interventions, from emphasizing the use of phototimers instead of institutional memory of manual techniques to improvements in our phototimer calibration. …”
Publicado 2016
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37698por Capizzi, Irene, Teta, Luigi, Vigotti, Federica Neve, Tognarelli, Giuliana, Consiglio, Valentina, Scognamiglio, Stefania, Piccoli, Giorgina Barbara“…The case here described regards a 71-year-old man, with obesity-related glomerulopathy; referral data were: weight 110 kg, Body Mass Index (BMI) 37 kg/m(2), serum creatinine (sCr) 5 mg/dL, estimated glomerular filtration rate (eGFR) 23 mL/min, blood urea nitrogen (BUN) 75 mg/dL, proteinuria 2.3 g/day. …”
Publicado 2017
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37699por Cukier, HN, Kunkle, BK, Hamilton, KL, Rolati, S, Kohli, MA, Whitehead, PL, Jaworski, J, Vance, JM, Cuccaro, ML, Carney, RM, Gilbert, JR, Farrer, LA, Martin, ER, Beecham, GW, Haines, JL, Pericak-Vance, MA“…RESULTS: Rare variants were found in known AD risk genes including AKAP9, CD33, CR1, EPHA1, INPP5D, NME8, PSEN1, SORL1, TREM2 and UNC5C. …”
Publicado 2017
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37700“…Remarkably, LILE significantly decreased the cellulose crystallinity index (CrI) of switchgrass by significantly increasing both the arabinose substitution degree in xylan and the content of ammonium oxalate-extractable uronic acids, both favoring cellulose digestibility. …”
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