“…Renal function was evaluated and confirmed using blood urea nitrogen and serum Cr levels. In parallel, the hypoxia-induced NRK-52E cell model was employed, and miR-195-5p was found to be markedly reduced under hypoxic conditions. …”
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“…All these patients were treated with acute lymphoblastic leukemia type (ALL-type) chemotherapy and complete remission (CR) were reached in 4 patients. The median follow-up was 9.5 (7–37) months, median progression free survival was 7 months; while median overall survival was 9 months. …”
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“…Technical success rate was 100%, while a complete response + partial response (CR + PR) was documented in 70.83%, 79.17%, 83.33%, and 79.17% of patients at 3, 6, 12, and 24 months post-ISI, respectively. …”
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“…RESULTS: All of the 118 patients with NSCLC were available for evaluation of efficacy. Complete response (CR, 0 case), partial response (PR, 10 cases), stable disease (SD, 79 cases) and progressive disease (PD, 29 cases) were evaluated according to RECIST version 1.1. …”
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“…Objective response was 4% and clinical benefit rate (CR + PR + SD > 6 m) was 19%. T-cell exhaustion (CD8(+ )PD-1(+)/CTLA-4(+)) and treatment-induced depletion of regulatory T-cells (CD4(+) Foxp3(+)/CTLA-4(+)) was seen in tumor or blood in 5/5 patients with clinical benefit, but only in one non-responder. …”
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“…In the current work, we first established normal airway epithelial cells (upper and lower airway track) in 2D and 3D culture systems using conditional reprogramming (CR) and air-liquid interface (ALI) techniques. These long-term cultures maintained differentiation potential. …”
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“…Global Position System (GPS) monitors were used to collect and compute external workloads and individual tactical actions, and Borg Scale CR10 was used to evaluate RPE. High-Superiority (4v2), Superiority (4v3), and Very Low-Cooperation (4v2+0) formats allow players in balanced teams to cover more distance while walking; on the other side, Inferiority (4v5), High-Inferiority (4v6), and Very High-Cooperation (4v2+4) allow players to sprint more and practice more tactical individual actions as a resultant emergent behavior; all players in SSG conditions with a lower number of conditions, perceived the exercise as more intense, especially in situations with less than two players. …”
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“…Molecular characteristics such as the distribution of substance P and the calcium-binding proteins parvalbumin (PV) and calretinin (CR) indicate, that the zebrafish extended centromedial (autonomic and reproductive) amygdala is predominantly located in the GABAergic and isl1-negative territory. …”
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“…From July 2012 to September 2015, a total of 68 patients with stage IIIA and IIIB SCLC who had completed 3-4 cycles of etoposide plus cisplatin/carboplatin and achieved clinical complete response (cCR) or clinical partial response (cPR) were randomized into the two groups equally. …”
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“…Of these four loci, A, H and L functioned on both central rows (CR) and lateral rows (LR) of the barley spikes, while B exhibited effect only on LR. …”
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“…We estimate that RDTs in primigravidae at first antenatal visit are substantially more sensitive than in non-pregnant adults (OR = 17.2, 95% Cr.I. 13.8-21.6), and that sensitivity declines in subsequent visits and with gravidity, likely driven by declining susceptibility to placental infection. …”
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“…The best model with statistically significant parameters has squared correlation coefficient R(2)= 0.802, adjusted squared correlation coefficient R(2)(adj) = 0.767, Leave one out (LOO) cross-validation coefficient (Q(2)) = 0.693, lack of fit score (LOF) = 0.406, R(2)(Test) = 0.77, Y-randomization test (cR(2)p) = 0.714, Chi-squared (χ(2)) =0.026, bootstrapping (Systematic errors = 0.272) and Variance Inflation Factor (VIF) <2 . …”
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“…As of data collection, two patients achieved complete remission (CR) after 4, 6 cycles of treatment, respectively, and another patient was evaluated as partial remission (PR) after 2 cycles. …”
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“…In addition, SeF significantly increased the concentrations of zinc (Zn), calcium (Ca), magnesium (Mg) in both cultivars, but decreased the concentration of chromium (Cr), cadmium (Cd) and lead (Pd), which phenomenon was more significant in 202w17. …”
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“…Machangara River was the only one that registered higher Cr concentrations than the national guidelines. …”
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“…Blood samples were digested in closed vessels using a microwave and ICP-MS was used to determine the concentrations of 12 metallic elements (Ba, Be, Ca, Co, Cr, Cu, Fe, Mg, Mo, Ni, Pb and Zn). In MS patients, we observed a reduction in the concentrations of beryllium, copper, chromium, cobalt, nickel, magnesium and iron. …”
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“…The basic soil properties were examined under selected plant communities (pH, C(org), N(t)), available forms of elements (P, K, Mg), and as plant nutrients and heavy metal occurrence (Fe, Zn, Mn, Co, Cd, Pb, Sr, Cr, Cu). The soil organic carbon (C(org)) content varied from 3.17 ± 0.007% to 17.7 ± 0.21% and significant differences were observed between sites. …”
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“…Coatings were deposited using the atmospheric plasma spraying (APS) process (ceramic layer and bond-coat) on the Ni-based superalloy substrate with Ni-22Cr-10Al-1Y bond-coat. The thickness of the ceramic top-coats in all cases were 300 µm. …”
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“…Internal consistency was determinedusing both Cronbach’s alpha and composite reliability (CR). Validity was assessed by constructvalidity, including ordinal regression, ordinal exploratory factor analysis (OEFA), and ordinalconfirmatory factor analysis (OCFA). …”
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“…Pearson's correlation analysis showed correlation of lncRNA MALAT1 levels with ACR, urine β2-microglobulin (β2-MG), urine α1-microglobulin (α1-MG), creatinine (Cr), and glycosylated hemoglobin (HbA1c), while negative with superoxide dismutase (SOD) (r = −0.388, P < 0.05). …”
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