“…The bis‐NSAID/CUR‐BF(2) and bis‐NSAID‐CUR hybrids exhibited low cytotoxicity in NCI‐60 assay, and in independent cell viability assay on colorectal cancer (CRC) cells (HCT116, HT29, DLD‐1, RKO, SW837, CaCo2) and in normal CR cells (CCD841CoN). By contrast, the mono‐naproxin and mono‐flurbiprofen CUR‐BF(2) adducts exhibited remarkable anti‐proliferative and apoptopic activity in NCI‐60 assay most notably against HCT‐116 (colon), OVCAR‐3 (ovarian), and ACHN (renal) cells. …”
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“…By definition, we considered a poor response as progressive disease (PD) and stable disease (SD), while complete response (CR) and partial response (PR) were considered as a good response. …”
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“…This study assesses the consequences and results of patients undergoing transabdominal preperitoneal (TAPP) inguinal hernia repair using P4HB mesh (Phasix(TM), C.R. Bard Inc., Murray Hill, NJ, USA). METHODS: We performed a pilot study of laparoscopic TAPP repair for inguinal hernias using P4HB mesh in 15 patients (14 male and one female) with an average age of 55.8 y, and an average body mass index of 27.4 kg/m(2). …”
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“…HAdV-Cs are well known for lysing cells owing to the E3 CR1-β-encoded adenovirus death protein (ADP). We previously reported a high-throughput image-based screening framework and identified an inhibitor of HAdV-C2 multiround infection, nelfinavir mesylate. …”
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“…The specimen surfaces were treated using CoJet sandblasting, 50 µm Al(2)O(3) sandblasting, % 9 HF (hydrofluoric) acid, ER,Cr:YSGG laser treatment, and Z-Prime. Dual-cure resin cements (TheraCem and 3M RelyX U 200) were applied on each specimen's treated surface. …”
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“…The study was performed using the industrial xylose-fermenting S. cerevisiae strain CR01. Adding a mixture of pyridoxine, thiamine, and biotin to unadapted propagation cultures improved cell growth and ethanol yields during fermentation in wheat straw hydrolysate from 0.04 g g(−1) to 0.19 g g(−1) and in corn stover hydrolysate from 0.02 g g(−1) to 0.08 g g(−1). …”
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“…Analysis of individual data indicated that MCarn is relatively stable in the absence of intervention, and effectually all participants respond to BA supplementation (99.3% response [95%CrI: 96.2–100]).…”
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“…The spectrum of side effects and pCR rates under therapy with the biosimilar were comparable to the experiences made with the reference drug. …”
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“…Then, she underwent left-side modified radical mastectomy (MRM) and achieved pathologic complete response (pCR), as confirmed by postoperative pathology. The patient held on receiving 2 cycles of the targeted therapy plus chemotherapy with trastuzumab, paclitaxel plus cisplatin (TPC) and adjuvant radiation therapy but continued to receive targeted therapy with trastuzumab and pertuzumab during the 1-year follow-up period. …”
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“…A high PTA (≥ 90%) for a target of 80% with a MIC of 4 μg/mL in patients with CL(CR) 60–120 mL/min and flow rate of ECMO circuit 3–5.5 L/min was observed when imipenem was administered by a 4-h infusion of 1 g every 6 h. …”
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“…The leachability of Zn, Ni, Cu, Cr, and Mn from SS biochars was similar to raw SS. …”
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“…These results suggest that, most metal ions are predominantly bonded to sulphate, sulphide, and carbonate coal minerals. Alternatively, Ce, Cr and Y showed total extraction recoveries of ≤ 90%, confirming their strong affinity towards quartz coal minerals. …”
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“…Hierarchical cluster analysis of dorsal hippocampal microglia across the three groups based on morphology and expression of MHCII, CX3CR1, CD68 and IBA1 revealed five distinct phenotypes. …”
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“…No statistical difference was noticed in complete response (CR), partial response (PR), and no response (NR) between these two groups. …”
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“…It was found that the content of most elements (B, Cd, Co, Cr, Fe, Mn, Mo, Ni, Pb, Zn) did not exceed the permissible values according to the Regulation of the Minister of the Environment on soil quality standards; however, in the case of Cu, the limit values established for forest and agricultural soils were exceeded, with the highest Cu contents found in the ‘C’ category. …”
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“…Therefore, the aim of our study was to analyze whether the articular surface of cobalt-chrome (CoCr) femoral heads is significantly altered in the setting of a metal-on-cement articulation during the interim period of two-stage revision for PJI. …”
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“…After TIPS, the following results were obtained: a complete response (CR), partial response (PR), or absent RA response (AR) of 38 [55.9%], 21 [30.9%], and 9 [13.2%], respectively. …”
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“…Arc and laser welding of AlCoCrFeNi HEAs results in lower hardness in the FZ and HAZ and reduced overall strength. …”
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