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38201por Wu, Jiazhu, Miao, Yi, Qian, Chuan, Tao, Pengfei, Wang, Xicheng, Dong, Xingqi, Li, Xia, Lou, Jincheng, Liang, Jinhua, Xu, Wei, Li, Jianyong, Min, Haiyan“…Of the 45 patients evaluated at the end of treatment, 26 (58%) achieved CR, 6 (13%) achieved PR and 6 (13%) experienced progressive disease. …”
Publicado 2021
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38202por Cowell, Whitney, Colicino, Elena, Levin-Schwartz, Yuri, Enlow, Michelle Bosquet, Amarasiriwardena, Chitra, Andra, Syam S., Gennings, Chris, Wright, Robert O., Wright, Rosalind J.“…We measured As, Ba, Cd, Cs, Cr, Pb, and Sb in urine, collected on average during late pregnancy, by ICP-MS. …”
Publicado 2021
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38203por Li, MinMing, Li, Chao, Geng, SuXia, Chen, XiaoMei, Wu, Ping, Deng, ChengXin, Chen, XiaoFang, Lu, ZeSheng, Weng, JianYu, Du, Xin“…The overall response rate (ORR), marrow complete remission (mCR), plus hematological improvement (HI) rates of the MST-DAC group were higher than that of the DAC group (81.8 vs. 54.5%, p = 0.36; 63.6 vs. 27.3%, p = 0.09, respectively); however, there were no statistical differences between the two groups, which may be attributed to the limited number of cases evaluated in this study. …”
Publicado 2021
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38204por Chen, Kai, Wang, Qi, Li, Mingzhe, Guo, Huahu, Liu, Weikang, Wang, Feng, Tian, Xiaodong, Yang, Yinmo“…FUNDING: This study was supported by The Natural Science Foundation of China (NO.81572339, 81672353, 81871954) and the Youth Clinical Research Project of Peking University First Hospital (2018CR28).…”
Publicado 2021
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38205por Nittler, Larry R., Alexander, Conel M. O’D., Patzer, Andrea, Verdier‐Paoletti, Maximilien J.“…The similar abundances, isotopic distributions, silicate/oxide ratios, and grain sizes of the presolar O‐rich grains found here to those of presolar grains in highly primitive CO, CR, and ungrouped carbonaceous chondrites (CCs) indicate that the CM parent body(ies) accreted a similar population of presolar oxides and silicates in their matrices to those accreted by the parent bodies of the other CC groups. …”
Publicado 2021
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38206“…Ea 680 was the single isolate revealing a new CRISPR genotype due to a novel CR2 spacer located closer to the leader sequence and therefore thought to be recently acquired. …”
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38207“…KEY POINTS: • Cas12a is a powerful tool for genome engineering and transcriptional perturbation • Cas12a causes less toxic side effects in bacteria than Cas9 • Self-processing of crRNA arrays facilitates multiplexing approaches…”
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38208“…Here, we report a 64-year-old patient diagnosed with mCRC who experienced a complete pathological response (pCR) after successfully conversion treatment with pembrolizumab and RT, and remains to be tumor-free during a follow-up of 11 months while off therapy. …”
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38209por Wiśniewski, Adam, Filipska, Karolina, Piec, Katarzyna, Jaskólski, Filip, Ślusarz, Robert“…The Bland–Altman analysis showed a good coefficient of repeatability (CR) of 0.46, a 95% confidence interval (CI) of 0.41–0.53, and excellent intraclass correlation coefficients or weighted kappa values (>0.90), reflecting high reliability and reproducibility. …”
Publicado 2021
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38210“…Aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), blood urea nitrogen (BUN), creatinine (Cr), and liver-type fatty acid binding protein (L-FABP) were examined in the rat cardiopulmonary bypass model to ascertain organ damage. …”
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38211por Hong, Goohyeon, Kim, Yu-Il, Park, Seoung Ju, Lee, Sung Yong, Kim, Jin Woo, Yoon, Seong Hoon, Lee, Keu Sung, Byun, Min Kwang, Kim, Hak-Ryul, Chung, Jaeho“…Background: Hederacoside C from ivy leaf dry extracts (HH) and berberine from Coptidis rhizome dry extracts (CR) can be combined (HHCR) as a herbal product. …”
Publicado 2021
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38212por Macedo, Ana, Gómez, Carlos, Rebelo, Miguel Ângelo, Poza, Jesús, Gomes, Iva, Martins, Sandra, Maturana-Candelas, Aarón, Pablo, Víctor Gutiérrez-de, Durães, Luis, Sousa, Patrícia, Figueruelo, Manuel, Rodríguez, María, Pita, Carmen, Arenas, Miguel, Álvarez, Luis, Hornero, Roberto, Lopes, Alexandra M., Pinto, Nádia“…OBJECTIVE: The aim of this work is to analyze the association between sixteen genes previously related with AD: APOE, PICALM, CLU, BCHE, CETP, CR1, SLC6A3, GRIN2 β, SORL1, TOMM40, GSK3 β, UNC5C, OPRD1, NAV2, HOMER2, and IL1RAP, and the slowing of the brain activity, assessed by means of RP at the aforementioned frequency bands. …”
Publicado 2021
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38213“…Moreover, the complete remission (CR) rate for the TWG + ARB and ARB groups in the 9th month were 45.7% and 15%, respectively (p = 0.044). …”
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38214por Clemmensen, Helena Strand, Dube, Jean-Yves, McIntosh, Fiona, Rosenkrands, Ida, Jungersen, Gregers, Aagaard, Claus, Andersen, Peter, Behr, Marcel A., Mortensen, Rasmus“…In contrast, infection with an MPT70-overexpressing Mtb strain promoted highly differentiated KLRG1(+)CX3CR1(+) CD4 T cells with limited lung-homing capacity. …”
Publicado 2021
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38215por Wang, Zijing, Cai, Ruopeng, Wang, Gang, Guo, Zhimin, Liu, Xiao, Guan, Yuan, Ji, Yalu, Zhang, Hao, Xi, Hengyu, Zhao, Rihong, Bi, Lanting, Liu, Shanshan, Yang, Li, Feng, Xin, Sun, Changjiang, Lei, Liancheng, Han, Wenyu, Gu, Jingmin“…The emergence of multi-drug resistant (MDR) K. pneumoniae and carbapenem-resistant hypervirulent K. pneumoniae (CR-hvKP) has brought more severe challenge to the treatment of K. pneumoniae infection. …”
Publicado 2021
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38216por Sprenger, Philipp P, Hartke, Juliane, Schmitt, Thomas, Menzel, Florian, Feldmeyer, Barbara“…Expression of these candidate genes was often mirrored in the CHC profiles. For example, Cr. levior A, which has longer CHCs than its cryptic sister species, had a higher expression of elongases and a lower expression of fatty acyl- CoA reductases. …”
Publicado 2021
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38217“…Accordingly, this study aimed to investigate the color stability, surface microhardness, and surface roughness of resin-modified glass ionomer (RMGIC), amalgomer CR, nanohybrid, and bulk-fill resin composites restorative materials after frequent exposure to a desensitizing agent. …”
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38218por Dicu, T., Burghele, B. D., Botoş, M., Cucoș, A., Dobrei, G., Florică, Ș., Grecu, Ș., Lupulescu, A., Pap, I., Szacsvai, K., Țenter, A., Sainz, C.“…In this sense, radon measurements were continuously carried out, using a newly developed smart device accompanied by CR-39 detectors, for one full year, in 71 residential buildings located in 5 Romanian cities. …”
Publicado 2021
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38219“…The analysis results show that the genome structures of the subfamilies and the newly sequenced two species are very similar, and the size of the CR region is significantly related to the repeat unit. …”
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38220por Stickeler, Elmar, Aktas, Bahriye, Behrens, Annika, Belleville, Erik, Ditsch, Nina, Fasching, Peter A., Fehm, Tanja N., Hartkopf, Andreas D., Jackisch, Christian, Janni, Wolfgang, Kolberg-Liedtke, Cornelia, Kolberg, Hans-Christian, Lüftner, Diana, Lux, Michael P., Müller, Volkmar, Schneeweiss, Andreas, Schütz, Florian, Schulmeyer, Carla E., Tesch, Hans, Thomssen, Christoph, Uleer, Christoph, Untch, Michael, Welslau, Manfred, Wöckel, Achim, Wurmthaler, Lena A., Würstlein, Rachel, Thill, Marc“…For other therapies such as immune checkpoint inhibitors, which have successfully improved the rate of pathologic complete response (pCR) in neoadjuvant treatment settings for patients with triple-negative breast cancer (TNBC), there is a growing understanding of the quality of life and side effects. …”
Publicado 2021
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