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“…In the current study, we demonstrate a CRISPR/Cas12a-based collateral cleavage method for COVID-19 diagnosis using the Cas12a/crRNA complex for target recognition, reverse transcription loop-mediated isothermal amplification (RT-LAMP) for sensitivity enhancement, and a novel DNA capture probe-based lateral flow strip (LFS) or real-time fluorescence detector as the parallel system readout facility, termed CRICOLAP. …”
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“…The median value and interquartile range of urinary L‐FABP levels were 6.66 and 3.37–21.1 μg/gCr, respectively. Urinary L‐FABP levels were significantly correlated with both beta‐2 microglobulin and cystatin C levels; the correlation with the former was higher than that with the latter. …”
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“…Cronbach’s alpha, composite reliability, and convergent-related validity were considered very good for the FSOC Scale (α = 0.956; CR = 0.974; AVE = 0.689). No evidence of discriminant-related validity was found for the dimensions of FSOC. …”
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“…Thirty-one patients received IMRT for pleural dissemination and the response rate (CR + PR) was 97%. The mean local control time was 40 months (95% CI, 32.6–47.3 months). …”
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“…Geo-environmental and geotechnical tests were performed on shredded samples and a digestion method was applied to detect the metals As, Cd, Cr, Cu, Fe, Mn, Ni, Pb, and Zn concentrations using an ICP OES. …”
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“…The m/z values of 13,895.80 were downregulated after R-CHOP treatment in DLBCL patients who obtained complete remission (CR) (P=0.018). CONCLUSIONS: The potential independent serum biomarkers for diagnosis as well as prognosis of DLBCL could be provided for rapid identification.…”
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“…METHODS: This observational analytical study was carried out based on data collected by the Cancer Registration Center affiliated to the Vice Chancellery for Health of Babol University of Medical Sciences, North of Iran, during 2008-2017. Crude incidence rate (CR), and age-standardized incidence rate (ASR) have been calculated for different GI cancers, based on the primary involved site; and have been compared in different years, patients' age, gender and place of residence. …”
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“…Furthermore, the median NLR was dramatically increased in low NLR group when patients achieved complete remission (CR). CONCLUSIONS: Pretreatment NLR as a marker can predict the prognosis and NLR can assess the response to chemotherapy in patients with non-M3 AML, especially in those cases with myeloblasts over 50% in BM.…”
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“…All 18 integron-positive E. coli carried the integron class I (int1) gene, and three different gene cassette arrangements, dfrA12+aadA2 (2 isolates), aac(6′)-Ib3+aac(6′)-Ib-cr+aadA4 (2 isolates), and dfrA17+aadA5 (1 isolate) were detected. …”
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“…No difference was noted in blood urea nitrogen (BUN), blood creatinine (Cr), TNF-α, and C-reactive protein (CRP) levels in group 1, group 2, and the healthy control group (P > 0.05). …”
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“…RESULTS: The NAA and Cho concentration increased after treatments and Cr concentration remained constant in both groups. …”
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“…Based on the concept of high-entropy alloys, the present work designed and prepared a novel Co(0.4)FeCr(0.9)Cu(0.3) antibacterial high-entropy alloy with superior antibacterial properties without intricate or rigorous annealing processes, which outperform the antibacterial stainless steels. …”
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“…In a separate experiment, brains of Cx3cr2(+/GFP)xCcr2(+/RFP) mice from ELA or control conditions were collected every 7 days after birth for assessment of neuroinflammation and central immune cell morphology and density. …”
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“…Complex compounds of transition metal ions such as Fe(II), Cr(III) and Zr(II) containing pyridine or quinoline as ligands show at least moderate catalytic activity in ethylene and propylene polymerizations. …”
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“…Microglia-specific ASK1 deletion was achieved using a CX3CR1(CreER) system, and we found that ASK1 signaling in microglia played a major role in generating and maintaining disease. …”
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“…Moreover, incubation of A549 cells expressing ACE2 with purified VIM increased pseudotyped SARS-CoV-2-S entry. CR3022 antibody, which recognizes a distinct epitope on SARS-CoV-2-S-RBD without interfering with the binding of the spike with ACE2, inhibited the binding of VIM with CoV-2 S-RBD, and neutralized viral entry in human endothelial cells, suggesting a key role for VIM in SARS-CoV-2 infection of endothelial cells. …”
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