“…The adaptation capacity of TALEs inversely correlates with the number of mismatches with the EBE. LbCas12a/crRNA is known to generate longer deletion than Cas9. …”
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“…The contamination profile of heavy metal depicted that Pb showed highest conc. 0.065 mg/g followed by Co (0.053 mg/g) and Ni with 0.52 mg/g in the soil. Pb and Cr had high conc. in soil samples around brickkilns due to burning of coal and rubber tyres as fuel. …”
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“…In the present work, bismuth borate glass samples with the composition of (99-x) B(2)O(3) + 1Cr(2)O(3) + (x) Bi(2)O(3) (x = 0, 5, 10, 15, 20, and 25 wt %) were prepared using the melt quenching technique. …”
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“…The PS prosthesis design had a higher OR (4.1) than the CR design. Younger age (50–59 years, OR 1.5) and PS prosthesis (OR 2.7) were significant predictors of secondary patellar resurfacing. …”
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“…Binding to the cellular ACE2 receptor and the conformation-dependent CR3022 antibody showed that the RBD glycosylation variants carrying blood group antigens were functional. …”
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“…METHODS: To design allele-specific CRISPR RNAs (crRNAs) targeting the signature mutations in the spike protein of Omicron variant, and to develop a CRISPR-Cas12a-based assay to specifically detect Omicron variant. …”
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“…The confirmatory factor analysis (CFA) ensured the great construct validity (χ(2)/SD = 1.725, goodness of fit index (GFI) = 0.916, and root mean square error of approximation (RMSEA) = 0.048), convergent validity (the factor loads of each item corresponding to each latent variable >0.6, average variance extracted (AVE) > 0.5, and composite reliability (CR) > 0.7), and discrimination validity (all of the absolute value of correlation coefficient are <0.5,and less than the square root of AVE) of the SSE. …”
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“…To evaluate the differences between TOF children (n = 9) and healthy children (n = 9), resting-state functional magnetic resonance imaging (rs-fMRI) and the Wechsler Intelligence Scale for Children–Chinese revised edition (WISC-CR) were conducted in this study. The results showed that TOF children had a lower full-scale intelligence quotient (FSIQ, 95.444 ± 5.354, p = 0.022) and verbal intelligence quotient (VIQ, 92.444 ± 4.708, p = 0.003) than healthy children (FSIQ = 118.500 ± 4.330;VIQ = 124.250 ± 4.404), and that significant differences in regional homogeneity (ReHo) and amplitude of low-frequency fluctuation (ALFF) existed between the two groups. …”
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“…The study deals with floodplain soil contamination caused by 8 heavy metals (HMs) (Cd, Co, Cr, Cu, Mo, Ni, Pb, Zn) originating and transported from old mine works along the Štiavnica River in Slovakia. …”
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“…Only 2 chemokine genes, CXCL10 and CX3CR1, had significantly different expression levels in the presence or absence of MCPyV infection in TLS-negative samples. …”
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“…Transcriptomic analyses by RNA-Seq of total sorted blood monocytes demonstrate that in comparison to the control groups, HESNs present increased expression levels of FCGR2C, FCAR, ITGAX, ITGAM, CR2, CD68, and CD163 genes, associated with effector functions. …”
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“…Optical readout of electric and magnetic field tuning of mechanical resonance in a CrOCl/graphene vdW NOEMS is further demonstrated. …”
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“…Several studies demonstrated that the real prognostic value of complete remission (CR) relies on sustained undetectable minimal residual disease (MRD). …”
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“…ORR for all arms was 82.3% (28/34; 95% CI: 65.5% to 93.2%) with a complete response (CR) rate of 42.4% (14/33; 95% CI: 25.5% to 60.8%). …”
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“…To obtain the optimal processing parameters of ultrasonic roll extrusion, 42CrMo bearing steel was taken as the research object, and the orthogonal test method was used to design an ultrasonic roll extrusion experiment with spindle speed, feed speed, static pressure and amplitude as parameters. …”
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“…The most common covariates were creatinine clearance (CrCL) and body weight. DISCUSSION: Although these studies included several covariates and total clearance (CL) was close, but the external validation of some models was poorly correlated between the actual and predicted value. …”
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“…An adjusted version of the Hooper questionnaire was used to monitor the perceptive sleep quality, readiness, fatigue, and delayed onset muscle soreness (DOMS) early in the morning. The CR-10 Borg’s scale was also used for monitoring the rate of perceived exertion (RPE) of players after training sessions. …”
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“…Complete pathological response (pCR) was 28.57%. They were 66.67%, 50.00% and 33.33% in RABSR group, respectively. …”
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“…Secondary attack rate among close contacts of cases with Delta was 1.4%, and 73.1% (95% credible interval (CrI): 32.9–91.4) of the transmissions occurred before onset. …”
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