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39001por Sancini, Giulio, Farina, Francesca, Battaglia, Cristina, Cifola, Ingrid, Mangano, Eleonora, Mantecca, Paride, Camatini, Marina, Palestini, Paola“…Milano winter fine particles (PM2.5win) are characterized by the presence of nitrate, organic carbon fraction, with high amount of polycyclic aromatic hydrocarbons and elements such as Pb, Al, Zn, V, Fe, Cr and others, with a negligible endotoxin presence. …”
Publicado 2014
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39002“…METHODS: Fifty patients received renal allografts from deceased donors were analyzed, including 35 patients with normal renal function (control group), 10 AR patients and 5 ATN patients. Cortical R2* (CR2*) and medullary R2* (MR2*) were measured by BOLD MRI. …”
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39003por Allison, David B., Antoine, Lisa H., Ballinger, Scott W., Bamman, Marcas M., Biga, Peggy, Darley-Usmar, Victor M., Fisher, Gordon, Gohlke, Julia M., Halade, Ganesh V., Hartman, John L., Hunter, Gary R., Messina, Joseph L., Nagy, Tim R., Plaisance, Eric P., Powell, Mickie L., Roth, Kevin A., Sandel, Michael W., Schwartz, Tonia S., Smith, Daniel L., Sweatt, J. David, Tollefsbol, Trygve O., Watts, Stephen A., Yang, Yongbin, Zhang, Jianhua, Austad, Steven N.“…These included: (1) Calorie restriction (CR) longevity response, (2) role of mTOR (mechanistic target of Rapamycin) and related factors in lifespan extension, (3) nutrient effects beyond energy (especially resveratrol, omega-3 fatty acids, and selected amino acids), 4) autophagy and increased longevity and health, (5) aging-associated predictors of chronic disease, (6) use and effects of mesenchymal stem cells (MSCs), (7) telomeres relative to aging and energetics, (8) accretion and effects of body fat, (9) the aging heart, and (10) mitochondria, reactive oxygen species, and cellular energetics. …”
Publicado 2014
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39004por Enang, O E, Otu, A A, Essien, O E, Okpara, H, Fasanmade, O A, Ohwovoriole, A E, Searle, J“…TRIAL REGISTRATION NUMBER: CRS/MH/CR-HREC/020/Vol.8/43…”
Publicado 2014
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39005por Wu, Jie, Qiu, Ling, Guo, Xiu-zhi, Xu, Tao, Cheng, Xin-qi, Zhang, Lin, Li, Peng-chang, Di, Qian, Wang, Qing, Ni, Lan, Zhu, Guang-jin“…Furthermore, multivariate logistic regression showed that carriers of the APOE-ε2ε3 genotype (P = 0.001, OR = 2.194) and the ε2 allele (P = 0.001, OR = 2.099) were significantly more likely to experience hyperuricemia than carriers of the ε3/ε3 genotype and the ε3 allele after adjustment for sex, body mass index (BMI), diastolic blood pressure (DBP), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), creatinine (Cr) and fasting blood glucose(FBG). CONCLUSIONS: The APOE-ε2ε3 genotype and the APOE-ε2 allele are associated with serum uric acid levels in Chinese subjects, indicating that individuals carrying the APOE-ε2 allele have a higher risk of hyperuricemia than non-carriers.…”
Publicado 2014
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39006por Castellano, Daniel, Puente, Javier, de Velasco, Guillermo, Chirivella, Isabel, López-Criado, Pilar, Mohedano, Nicolás, Fernández, Ovidio, García-Carbonero, Icíar, González, María Belén, Grande, Enrique“…Two patients (2%) achieved CR, 23 (22.5%) patients had PR, and 42 (41.2%) presented SD as best response. …”
Publicado 2014
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39007“…We used the simulator to assess the signal detection properties and localization accuracy of standard lesion–deficit correlation methods, under a simple truth model — that a critical region of interest (CR), when damaged, gives rise to a deficit. We considered voxel-based lesion-symptom mapping (VLSM) and proportional MAP-3 (PM3). …”
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39008
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39009por Huang, August Y, Xu, Xiaojing, Ye, Adam Y, Wu, Qixi, Yan, Linlin, Zhao, Boxun, Yang, Xiaoxu, He, Yao, Wang, Sheng, Zhang, Zheng, Gu, Bowen, Zhao, Han-Qing, Wang, Meng, Gao, Hua, Gao, Ge, Zhang, Zhichao, Yang, Xiaoling, Wu, Xiru, Zhang, Yuehua, Wei, LipingEnlace del recurso
Publicado 2014
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39010por Nouhaud, Elodie, Créhange, Gilles, Cueff, Adèle, Quivrin, Magali, Rouffiac-Thouant, Magali, Mineur, Laurent, Garcia, Robin, Chamois, Jérôme, Maingon, Philippe“…Responses were categorised as: Stable Disease (SD), Partial Response (PR), Complete Response (CR), Local Progression or Distant Progression in cases of new intra-hepatic lesions out-of-field or extra-hepatic metastases. …”
Publicado 2013
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39011por Tsang, Chi Man, Deng, Wen, Yip, Yim Ling, Zeng, Mu-Sheng, Lo, Kwok Wai, Tsao, Sai Wah“…EBV infection in human epithelial cells is a highly inefficient process compared to that in B cells, which express the complement receptor type 2 (CR2) to mediate EBV infection. Although receptor(s) on the epithelial cell surface for EBV infection remain(s) to be identified, EBV infection in epithelial cells could be achieved via the interaction of glycoproteins on the viral envelope with surface integrins on epithelial cells, which might trigger membrane fusion to internalize EBV in cells. …”
Publicado 2014
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39012por Donadello, Katia, Roberts, Jason A, Cristallini, Stefano, Beumier, Marjorie, Shekar, Kiran, Jacobs, Frédérique, Belhaj, Asmae, Vincent, Jean-Louis, de Backer, Daniel, Taccone, Fabio Silvio“…METHODS: We retrospectively reviewed data from critically ill patients treated with ECMO and matched controls who received a continuous infusion of vancomycin (35 mg/kg loading dose over 4 hours followed by a daily infusion adapted to creatinine clearance, CrCl)). The pharmacokinetics of vancomycin were described using non-linear mixed effects modeling. …”
Publicado 2014
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39013por Rahma, Osama E, Herrin, Vincent E, Ibrahim, Rami A, Toubaji, Anton, Bernstein, Sarah, Dakheel, Omar, Steinberg, Seth M, Eid, Rasha Abu, Mkrtichyan, Mikayel, Berzofsky, Jay A, Khleif, Samir N“…These PBMCs were cultured for a short time (48 hours only) and in the presence of GM- CSF, accordingly, they were identified as “Pre-Immature Dentritic Cells”. RESULTS: 51Cr release assay and ELISPOT demonstrated evidence of specific immune response against the relevant peptide in 10/16 (63%) evaluable patients in arm A and 7/12 (58%) in arm B. …”
Publicado 2014
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39014por Srkalovic, Gordan, Hussein, Mohamad A, Hoering, Antje, Zonder, Jeffrey A, Popplewell, Leslie L, Trivedi, Harsha, Mazzoni, Sandy, Sexton, Rachel, Orlowski, Robert Z, Barlogie, Bart“…The authors assessed the overall response rate, including confirmed complete response (CR) and partial response, in patients with relapsed/refractory multiple myeloma treated with sorafenib. …”
Publicado 2014
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39015por Wan, Zhihong, Wu, Yichen, Yi, Jing, You, Shaoli, Liu, Hongling, Sun, Zhiqiang, Zhu, Bing, Zang, Hong, Li, Chen, Liu, Fangfang, Li, Dongze, Mao, Yuanli, Xin, Shaojie“…Specifically, the PI had a higher accuracy than the CTP, MELD, or MELD-Na scoring for early prediction short-term survival of HBV-ACLF patients with normal levels of serum creatinine (Cr). The survival rate in low risk group (PI < 3.91) was 94.3%, which was markedly higher than those in the high-risk group (PI ≥ 3.91) (17.4%, P < 0.001). …”
Publicado 2015
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39016por Mello, Pâmela Carbone, Coppedê, Abílio Ricciardi, Macedo, Ana Paula, de Mattos, Maria da Gloria Chiarello, Rodrigues, Renata Cristina Silveira, Ribeiro, Ricardo Faria“…Greater result variance was obtained with OR, which presented the worse results opposed to Ni-Cr (10.45 ± 1.42 μm), and results similar to the best ones against composite (2.77 ± 0.69 μm). …”
Publicado 2009
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39017por Hallab, Nadim James“…Metal-on-metal total disc replacement components have significant increases in circulating metal (less than 10-fold that of controls at 4 ppb-Co and 3 ppb-Cr or ng/mL). Debris reactivity is local and systemic. …”
Publicado 2009
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39018por Tokajian, Sima, Eisen, Jonathan A., Jospin, Guillaume, Farra, Anna, Coil, David A.“…The isolate was also characterized by the concomitant presence of other resistance determinants most notably acc(6′)-lb-cr and qnrb1. The entire plasmid content was also investigated and revealed homology with four major plasmids pKPN-IT, pBS512_2, pRSF1010_SL1344, and pKPN3. …”
Publicado 2015
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39019por Sadeghi, Mahmoud, Lahdou, Imad, Ettinger, Jakob, Navid, Mojdeh Heidary, Daniel, Volker, Zeier, Martin, Hofmann, Jörg, Opelz, Gerhard, Schnitzler, Paul“…However, C-reactive protein (CRP) was significantly higher in patients with severe disease (62 vs 40 mg/l). TGF-β1/Cr was the most sensitive and specific marker associated with renal dysfunction. …”
Publicado 2015
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39020por Stacey, Simon N., Helgason, Hannes, Gudjonsson, Sigurjon A., Thorleifsson, Gudmar, Zink, Florian, Sigurdsson, Asgeir, Kehr, Birte, Gudmundsson, Julius, Sulem, Patrick, Sigurgeirsson, Bardur, Benediktsdottir, Kristrun R., Thorisdottir, Kristin, Ragnarsson, Rafn, Fuentelsaz, Victoria, Corredera, Cristina, Gilaberte, Yolanda, Grasa, Matilde, Planelles, Dolores, Sanmartin, Onofre, Rudnai, Peter, Gurzau, Eugene, Koppova, Kvetoslava, Nexø, Bjørn A., Tjønneland, Anne, Overvad, Kim, Jonasson, Jon G., Tryggvadottir, Laufey, Johannsdottir, Hrefna, Kristinsdottir, Anna M., Stefansson, Hreinn, Masson, Gisli, Magnusson, Olafur T., Halldorsson, Bjarni V., Kong, Augustine, Rafnar, Thorunn, Thorsteinsdottir, Unnur, Vogel, Ulla, Kumar, Rajiv, Nagore, Eduardo, Mayordomo, José I., Gudbjartsson, Daniel F., Olafsson, Jon H., Stefansson, Kari“…Here we show the discovery of four new BCC susceptibility loci: 2p24 MYCN (rs57244888[C], OR=0.76, P=4.7 × 10(−12)), 2q33 CASP8-ALS2CR12 (rs13014235[C], OR=1.15, P=1.5 × 10(−9)), 8q21 ZFHX4 (rs28727938[G], OR=0.70, P=3.5 × 10(−12)) and 10p14 GATA3 (rs73635312[A], OR=0.74, P=2.4 × 10(−16)). …”
Publicado 2015
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