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  1. 39641
    “…Twenty-one patients (16%) had a complete or partial response (CR/PR), and 30% of responses were durable for over 2 years. …”
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    Long-term Follow-up and Patterns of Response, Progression, and Hyperprogression in Patients after PD-1 Blockade in Advanced Sarcoma
  2. 39642
    “…The Wexner incontinence score, low anterior resection syndrome (LARS) score, fecal incontinence-related QoL, and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire-core questionnaire and 29-item module (EORTC QLQ-C30/CR29) were collected. Kaplan-Meier analysis was used to calculate local recurrence-free survival. …”
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    Oncological and functional outcomes of transanal total mesorectal excision in a teaching hospital in the Netherlands
  3. 39643
    “…Four color space models (RGB, hue-saturation-value (HSV), L*a*b*, and YCbCr models) were employed to calculate twelve color space parameters for each skin image. …”
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    Quantitative evaluation of radiodermatitis following whole-breast radiotherapy with various color space models: A feasibility study
  4. 39644
    “…Univariate and multivariate Logistic regression analyses showed that elevated TSH levels were significantly correlated with gender, FT3/FT4, total cholesterol (TC), TPO-Ab, Tg-Ab, creatinine (Cr), and triglycerides (TG). Among the four machine learning models, XGBoost performed best in the one-year task of predicting elevated TSH levels (AUC (0.87(+/- 0.03))). …”
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    Predicting Elevated TSH Levels in the Physical Examination Population With a Machine Learning Model
  5. 39645
    “…Two sampling sessions were scheduled in February and May 2019 and the occurrence of 24 metals (Hg, Ag, Al, As, Be, Bi, Cd, Co, Cr, Cu, Fe, Ga, In, Mg, Mn, Mo, Ni, Pb, Rb, Se, Sn, Ti, V, Zn) in bivalves was considered. …”
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    Occurrence of trace elements in Mediterranean mussels (Mytilus galloprovincialis Lamarck, 1819) from an experimental pilot farm in the Calich Lagoon (Sardinia, Italy)
  6. 39646
    “…Area under the curve for EGF to predict response was 0.80 (0.66–0.95). EGF ≥ 65.6 ng/ mgCr demonstrated 85% sensitivity and 71% specificity for response. …”
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    Predicting treatment response and clinicopathological findings in lupus nephritis with urine epidermal growth factor, monocyte chemoattractant protein-1 or their ratios
  7. 39647
    “…The main contribution of intrinsic SFD is the c-axis misalignment for the BN/FePt/MgTiON sample; however, the dispersed magnetic anisotropy has a higher input to intrinsic SFD for FePtCAg/MgTiOBN/CrRu film.…”
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    Switching Field Distribution in BN/FePtCAg/MgTiON and FePtCAg/MgTiOBN Films
  8. 39648
    “…Renal function was evaluated by measuring serum creatinine (sCr) and the glomerular filtration rate (GFR). We randomly grouped our cohort into three intervention groups to compare three different strategies for marathon recovery: total rest (REST), continuous running at their ventilatory threshold 1 (VT1) intensity (RUN), and elliptical workout at their VT1 intensity (ELLIPTICAL). …”
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    Renal Function Recovery Strategies Following Marathon in Amateur Runners
  9. 39649
    “…RS showed significantly higher values (p = 0.047) in patients with stable disease (SD)/progressive disease (PD) compared to patients with complete response (CR)/partial response (PR). CONCLUSIONS: We successfully clustered and constructed predictive models for TME-associated genes and helped guide immunotherapy strategies.…”
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    Identification of a Novel Tumor Microenvironment Prognostic Signature for Bladder Urothelial Carcinoma
  10. 39650
    “…BACKGROUND: The previous studies have identified several genes in relation to Alzheimer’s disease (AD), such as ABCA7, CR1, etc. A few studies have explored the association between the common variants, mainly in the non-coding regions of these genes, and cerebrospinal fluid (CSF) biomarkers. …”
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    Association Between Common Variants of APOE, ABCA7, A2M, BACE1, and Cerebrospinal Fluid Biomarkers in Alzheimer’s Disease: Data from the PUMCH Dementia Cohort
  11. 39651
    “…The heavy metal (Cd, Pb, Zn, Cu, Ni, and Cr) contents of previously studied soil samples from eleven floodplain sites along the Innerste River were re-analyzed statistically, and the levels of these metals in blackberry leaves were determined at five sites. …”
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    Heavy metal concentrations in floodplain soils of the Innerste River and in leaves of wild blackberries (Rubus fruticosus L. agg.) growing within and outside the floodplain: the legacy of historical mining activities in the Harz Mountains (Germany)
  12. 39652
    “…An exhaustive search coupled with first-principles calculations was implemented to investigate 10 Zintl compounds with a chemical formula of CaM(2)X(2) (M = Zn or Cd, X = N, P, As, Sb, or Bi) under three crystal structures: CaAl(2)Si(2)-, ThCr(2)Si(2)-, and BaCu(2)S(2)-type crystal phases. …”
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    Prediction of topological Dirac semimetal in Ca-based Zintl layered compounds CaM(2)X(2) (M = Zn or Cd; X = N, P, As, Sb, or Bi)
  13. 39653
    “…However, we show here that membranous HER3 protein is commonly highly expressed in lethal prostate cancer, associating with reduced time to castration resistance (CR) and survival. Multiplex immunofluorescence indicated that the HER3 ligand NRG1 is detectable primarily in tumor-infiltrating myelomonocytic cells in human prostate cancer; this observation was confirmed using single-cell RNA sequencing of human prostate cancer biopsies and murine transgenic prostate cancer models. …”
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    HER3 Is an Actionable Target in Advanced Prostate Cancer
  14. 39654
    “…We identified significant enrichment of transcriptomic signatures previously associated with PD, including for oxidative stress, phosphorylation, autophagy of mitochondria, cholesterol metabolism and inflammation, and the chemokine signaling proteins CX3CR1, CCR5, and CCR1. In addition, we identified genes in these peripheral cells that have previously been shown to be involved in PD pathogenesis and expressed in neurons, such as LRRK2, LAMP3, and aquaporin. …”
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    Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signatures
  15. 39655
    “…Macaques with lethal disease had rapid and profound loss of alveolar macrophages (AMs) and infiltration of activated CCR2(+) CX3CR1(+) interstitial macrophages (IMs) and neutrophils into lungs. …”
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    Infiltration of inflammatory macrophages and neutrophils and widespread pyroptosis in lung drive influenza lethality in nonhuman primates
  16. 39656
    “…Among these 593 (45.7%) had stage III disease, 1279 (98.6%) were grade III, 165 (13.0%) had peri-nodal extension (PNE), 212 (16.0%) lympho-vascular invasion (LVI), and 21 (1.6%) were metaplastic; 1256 (96.8%) received chemotherapy including 820 (63.2%) neoadjuvant with 306 (40.0%) pCR. Grade ≥3 toxicities occurred in 155 (12.4%) including two deaths and 3 s-primaries. 1234 (95.2%) underwent surgery [722 (55.7%) breast conservations] and 1034 (79.7%) received radiotherapy. …”
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    Outcomes of non-metastatic triple negative breast cancers: Real-world data from a large Indian cohort
  17. 39657
    “…Expression levels of 3 miRNA (miR-21, miR-210, and miR-376c-3p) were inconclusive in predicting therapeutic response, while ‘aberrant’ expression of circulating miR-199a predicted pathological complete response (pCR) to NAC. CONCLUSIONS: This systematic review outlines expression patterns of a number of miRNA which correlate with response to NAC and/or anti-HER2 therapies. …”
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    Overview of MicroRNA Expression in Predicting Response to Neoadjuvant Therapies in Human Epidermal Growth Receptor-2 Enriched Breast Cancer – A Systematic Review
  18. 39658
    por Moghnia, Ola H., Al-Sweih, Nourah A.
    Publicado 2022
    “…Furthermore quinolone resistance including oqxA/oqxB, aac(6′)-Ib-cr5, gyrA_D87N, gyrA_S83F, gyrA_S83L, parC_S80I, parE_S458A, parE_I355T, parC_S80I, and qnrB1. …”
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    Whole Genome Sequence Analysis of Multidrug Resistant Escherichia coli and Klebsiella pneumoniae Strains in Kuwait
  19. 39659
    “…Overall response rates including CR, CRi, and MLFS were comparable (44.0% for IC vs. 59.3% for VEN combination, p = 0.081), but VEN combination group compared to IC group tended to show lower treatment related mortality. …”
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    A retrospective comparison of salvage intensive chemotherapy versus venetoclax-combined regimen in patients with relapsed/refractory acute myeloid leukemia (AML)
  20. 39660
    “…Background andObjectives: Current guidelines on cardiac rehabilitation (CR) suggest moderate-intensity physical activity after acute coronary syndrome (ACS). …”
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    Effects of High Intensity Interval Training Rehabilitation Protocol after an Acute Coronary Syndrome on Myocardial Work and Atrial Strain
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