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  1. 39901
    “…Clinical activity was observed in 6/66 (9.1%) evaluable patients achieving response (CR/PR), with a median duration of response of 10.15 months (range: 2.99–41.95); 45/66 had stable disease (SD) per RECIST v1.1. …”
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    A phase I trial of LXS196, a protein kinase C (PKC) inhibitor, for metastatic uveal melanoma
  2. 39902
    “…Next, we constructed a GC cuproptosis-related (CR) signature (CRs) using Cox and least absolute shrinkage and selection operator (LASSO) regression analyses. …”
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    A cuproptosis-related signature for predicting the prognosis of gastric cancer
  3. 39903
    “…Within Braconidae, gene clusters tRNA(Trp)-tRNA(Cys)-tRNA(Tyr) and CR-tRNA(Ile)-tRNA(Gln)-tRNA(Met) were hotspots for gene rearrangement. …”
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    The mitochondrial genome of Binodoxys acalephae (Hymenoptera: Braconidae) with unique gene rearrangement and phylogenetic implications
  4. 39904
    “…CAD4TBv6 met the optimum TPP; with the threshold set to achieve a mean sensitivity of 95% (optimum TPP), specificity was 83.3%, (95% credible interval [CrI]: 83.0%—83.7%, CAD4TBv6 threshold: 55). There was considerable variation in accuracy by participant characteristics, with older individuals and those with previous TB having lowest specificity. …”
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    Accuracy of computer-aided chest X-ray in community-based tuberculosis screening: Lessons from the 2016 Kenya National Tuberculosis Prevalence Survey
  5. 39905
    “…The secondary outcome was embryo quality, including fertilization rate (FR), cleavage rate (CR), available embryo rate (AER), and good-quality embryo rate (GQER). …”
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    Relationship of the levels of reactive oxygen species in the fertilization medium with the outcome of in vitro fertilization following brief incubation
  6. 39906
    “…The neuron-microglia interaction in chronic nicotine-induced allodynia is mediated by increased expression of neuronal CX3CL1, which activates microglia by acting on CX3CR1 receptors on microglial cells. CONCLUSION: Together, these findings underlie a critical role of ACC microglia in the maintenance of ACC neuronal hyperactivity and resulting nociceptive hypersensitivity in chronic nicotine-treated mice. …”
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    Microglia sustain anterior cingulate cortex neuronal hyperactivity in nicotine-induced pain
  7. 39907
    “…Moreover, we identified that SEPT2-K74cr was correlated with poor prognosis and recurrence in HCC patients, thus indicating its clinical potential as an independent prognostic factor. …”
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    SEPT2 crotonylation promotes metastasis and recurrence in hepatocellular carcinoma and is associated with poor survival
  8. 39908
    “…BACKGROUND: Traditional cardiac rehabilitation (CR) is effective in improving physical performance and prognosis after myocardial infarction (MI). …”
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    Multi-domain lifestyle intervention in older adults after myocardial infarction: rationale and design of the PIpELINe randomized clinical trial
  9. 39909
    “…We analyzed the levels of cadmium (Cd), lead (Pb), and other metals and metalloids, including arsenic (As), barium (Ba), beryllium (Be), cobalt (Co), chromium (Cr), copper (Cu), iron (Fe), magnesium (Mg), manganese (Mn), molybdenum (Mo), selenium (Se), thorium (Th), thallium (Tl), uranium (U), vanadium (V), and zinc (Zn) in liver samples taken from three golden eagles and 36 white-tailed eagles that were found dead across Poland to verify their exposure. …”
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    Lead, cadmium, and other trace elements in the liver of golden eagles and white-tailed eagles: recent data from Poland and a systematic review of previous studies
  10. 39910
    por Feng, Yu, Shen, Jing
    Publicado 2023
    “…CONCLUSION: Our study systematically discovered 10 candidate hub genes (DPF2, ATG7, GSK3A, TFDP2, ACVR1, CX3CR1, AP4M1, DEPDC5, NR4A2, and IKBKB). A good diagnostic prediction model was obtained through comprehensive analysis in the training (AUC 0.91, CI 0.95–0.86) and validation group (AUC 0.94, CI 1.00–0.85). …”
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    Machine learning-based predictive models and drug prediction for schizophrenia in multiple programmed cell death patterns
  11. 39911
    “…Color change (∆E00) and translucency (TP, CR) were evaluated. Data were statistically analyzed (p < 0.05). …”
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    Effect of Different Artificial Staining Procedures on the Color Stability and Translucency of a Nano-Hybrid Resin-Based Composite
  12. 39912
    “…We show that therapy with revumenib was associated with a low frequency of grade 3 or higher treatment-related adverse events and a 30% rate of complete remission or complete remission with partial haematologic recovery (CR/CRh) in the efficacy analysis population. Asymptomatic prolongation of the QT interval on electrocardiography was identified as the only dose-limiting toxicity. …”
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    The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia
  13. 39913
    “…At this time, 55% of patients were in CR. (4) Conclusions: The use of bortezomib added to standard BeEAM HDCT is associated with relevant toxicities, particularly with regards to additional neuropathy. …”
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    Evaluation of Bortezomib-BeEAM (2BeEAM) as Chemotherapy Regimen Prior to ASCT in Patients with Mantle Cell Lymphoma
  14. 39914
    “…Therefore, the heavy metals’ mean concentration at the BA is above the WHO permissible limits of soil, i.e., 0.056 kg m(−3) (Ti), 0.085 kg m(−3) (Pb), 0.100 kg m(−3) (Cr) and 0.036 kg m(−3) (Cu). Furthermore, the heavy metal mean concentrations of TGH and VRAH present in the BA analysed samples were ranked in descending order: Ti > Zn > Fe and Ti > Fe > Zn, respectively. …”
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    Chemical characteristics of bottom ash from biomedical waste incinerators in Ghana
  15. 39915
    “…Glycoprotein expression changes in monocytes tolerized by the different TLR agonists were highly similar while S. aureus-stimulated monocytes shared some of the PAMP-induced changes but also exhibited a distinct expression profile. 11 glycoproteins (CD44, CD274, DSC2, ICAM1, LAMP3, LILRB1, PTGS2, SLC1A3, CR1, FGL2, and HP) were similarly up- or downregulated in all four comparisons in the tolerant cell state. …”
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    Staphylococcus aureus induces tolerance in human monocytes accompanied with expression changes of cell surface markers
  16. 39916
    “…Overall response rate (ORR) was 66% (48% CR; 17% PR); 52% patients underwent HDC-ASCT. An ORR of 85% was observed in patients with nongerminal center B-cell–like (non-GCB) DLBCL compared with only 13% in those with GCB DLBCL. …”
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    Carfilzomib combined with rituximab, ifosfamide, carboplatin, and etoposide for relapsed or refractory DLBCL
  17. 39917
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    Mechanism of Increased Spinal Cord Blood Flow due to Noradrenaline Administration Using Vascular Resistance: An Experimental Study Using a Canine Model
  18. 39918
    “…We found both cytotoxicity score of T cells and MHC score of B cells significantly increased after anti-PD-1 therapy in HBV+ ESCC patients. We also identified CX3CR1(high) T(EFF), a subset of CD8(+) T(EFF), associated with better clinical outcome in HBV+ ESCC patients. …”
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    Anti-PD-1 therapy achieves favorable outcomes in HBV-positive non-liver cancer
  19. 39919
    “…No such association was found in either concentric remodeling (CR) or eccentric hypertrophy (EH). Higher baseline E/A ratio was correlated with lower ΔRWT during the 5-year follow-up (β=−0.006 m/s, 95% CI: −0.012 to −0.002, P=0.025), which was independent of demographics and biological factors. …”
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    Echocardiography E/A Abnormality is Associated with the Development of Primary Left Ventricle Remodeling in Middle-Aged and Elderly Women: A Longitudinal Study
  20. 39920
    “…Claudin-1 expression also correlates with adverse survival outcomes, where only four of 20 claudin-1-positive patients who received neo-adjuvant chemotherapy (NAC) achieved pathological complete response (pCR). Conclusions The above presents a complex role of claudin-1 in TNBC patients. …”
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    Detection of Increased Expression of Claudin-1 in Triple-Negative Breast Cancer: Analysis and Clinical-Pathological Correlation
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