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40081por Pedersen, Stine S, Keller, Anna K, Nielsen, Marie K, Jespersen, Bente, Falborg, Lise, Rasmussen, Jan T, Heegaard, Christian W, Rehling, Michael“…The glomerular filtration rate (GFR) was calculated by renal clearance of (51)Cr-ethylenediaminetetraacetic acid, and apoptosis was quantified by immunohistochemical detection of caspase-3. …”
Publicado 2013
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40082por Scianni, Maria, Antonilli, Letizia, Chece, Giuseppina, Cristalli, Gloria, Di Castro, Maria Amalia, Limatola, Cristina, Maggi, Laura“…We investigated whether the activation of microglial CX(3)CR1 induces the release of factors that modulate NMDAR functions. …”
Publicado 2013
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40083por Liu, Bao-Tao, Yang, Qiu-E, Li, Liang, Sun, Jian, Liao, Xiao-Ping, Fang, Liang-Xing, Yang, Shou-Shen, Deng, Hui, Liu, Ya-Hong“…METHODS: The ESBL-encoding genes (bla (CTX-M), bla (TEM) and bla (SHV)), and PMQR (qnrA, qnrB, qnrS, qnrC, qnrD, aac(6’)-Ib-cr, qepA, and oqxAB) of these 696 isolates were determined by PCR and sequenced directionally. …”
Publicado 2013
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40084por Stoesser, N., Batty, E. M., Eyre, D. W., Morgan, M., Wyllie, D. H., Del Ojo Elias, C., Johnson, J. R., Walker, A. S., Peto, T. E. A., Crook, D. W.“…RESULTS: A wide variety of antimicrobial resistance genes were identified, including bla(CTX-M), bla(LEN), bla(OKP), bla(OXA), bla(SHV), bla(TEM), aac(3′)-Ia, aac-(3′)-IId, aac-(3′)-IIe, aac(6′)-Ib-cr, aadA1a, aadA4, aadA5, aadA16, aph(6′)-Id, aph(3′)-Ia, qnrB and qnrS, as well as resistance-associated mutations in chromosomal gyrA and parC genes. …”
Publicado 2013
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40085por He, Xiao-Hui, Li, Bo, Zou, Shuang-Mei, Dong, Mei, Zhou, Sheng-Yu, Yang, Jian-Liang, Xue, Li-Yan, Yang, Sheng, Liu, Peng, Qin, Yan, Zhang, Chang-Gong, Han, Xiao-Hong, Shi, Yuan-Kai“…Altogether, 16 patients underwent PBSCT, including 11 at first remission (CR1/PR1), 3 at second remission, and 2 with disease progression during first-line chemotherapy. …”
Publicado 2012
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40086por Ye, Fei, Zhang, Yibei, Liu, Yue, Yamada, Kazunari, Tso, Jonathan L., Menjivar, Jimmy C., Tian, Jane Y., Yong, William H., Schaue, Dörthe, Mischel, Paul S., Cloughesy, Timothy F., Nelson, Stanley F., Liau, Linda M., McBride, William, Tso, Cho-Lea“…Moreover, many upregulated genes highlighted maintenance and repair activities, including detoxifying lipid peroxidation products, activating lysosomal autophagy/ubiquitin-proteasome pathways, and enhancing telomere maintenance and DNA repair, closely resembling the anti-aging effects of caloric/glucose restriction (CR/GR), a nutritional intervention that is known to increase lifespan and stress resistance in model organisms. …”
Publicado 2013
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40087por Wang, Yujuan, Subramanian, Preeti, Shen, Defen, Tuo, Jingsheng, Becerra, S. Patricia, Chan, Chi-Chao“…We studied the effects of PEDF on focal retinal lesions in DKO rd8 (Ccl2(−/−)/Cx3cr1(−/−) on C57BL/6N [Crb1(rd8)]) mice, a model for progressive, focal rd (retinal degeneration). …”
Publicado 2013
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40088por Hohloch, Karin, Zwick, Carsten, Ziepert, Marita, Hasenclever, Dirk, Kaiser, Ulrich, Engert, Andreas, Höffkes, Heinz-Gert, Kroschinsky, Frank, Mesters, Rolf, Feller, Andreas C, Löffler, Markus, Trümper, Lorenz, Pfreundschuh, Michael“…RESULTS: 55 pts (median age 56 yrs) were evaluable for a final analysis with a median observation time of 9.3 years. The CR-rate was 77.4% ; the 5 and 8-year-EFS rates were 46.4% (95%CI 32.5-60.3%) and 43.5% (29.4-57.6%), respectively, and the 5- and 8 yr OS rates were 64.6% (51.7-77.5%) and 59.9% (46.4-73.4%). 14/55 patients have died due to lymphoma progression, and 2/55 patients (3.6%) due to treatment related toxicity, 4/55 due to other causes (3 infections, 1 acute heart failure). …”
Publicado 2014
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40089“…Color measurement of all specimens was recorded before and after exposure to staining agent with a colorimeter (Minolta CR-300). Color differences (∆E*) between the 2 color measurements (baseline and after 24 h storage) were calculated. …”
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40090por Wagner, Cordula, Thompson, Caroline A., Arah, Onyebuchi A., Groene, Oliver, Klazinga, Niek S., Dersarkissian, Maral, Suñol, Rosa, Klazinga, N, Kringos, DS, Lombarts, MJMH, Plochg, T, Lopez, MA, Secanell, M, Sunol, R, Vallejo, P, Bartels, P, Kristensen, S, Michel, P, Saillour-Glenisson, F, Vlcek, F, Car, M, Jones, S, Klaus, E, Bottaro, S, Garel, P, Saluvan, M, Bruneau, C, Depaigne-Loth, A, Shaw, C, Hammer, A, Ommen, O, Pfaff, H, Groene, O, Botje, D, Wagner, C, Kutaj-Wasikowska, H, Kutryba, B, Escoval, A, Lívio, A, Eiras, M, Franca, M, Leite, I, Almeman, F, Kus, H, Ozturk, K, Mannion, R, Arah, OA, DerSarkissian, M, Thompson, CA, Wang, A, Thompson, A“…MAIN OUTCOME MEASURES: Four measures of QM activities were evaluated at care pathway level focusing on specialized expertise and responsibility (SER), evidence-based organization of pathways (EBOP), patient safety strategies and clinical review (CR). RESULTS: Participating departments attained mean values on the various scales between 1.2 and 3.7. …”
Publicado 2014
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40091por Wagner, Cordula, Groene, Oliver, Thompson, Caroline A., Dersarkissian, Maral, Klazinga, Niek S., Arah, Onyebuchi A., Suñol, Rosa, Klazinga, N, Kringos, DS, Lombarts, K, Plochg, T, Lopez, MA, Secanell, M, Sunol, R, Vallejo, P, Bartels, P, Kristensen, S, Michel, P, Saillour-Glenisson, F, Vlcek, F, Car, M, Jones, S, Klaus, E, Garel, P, Hanslik, K, Saluvan, M, Bruneau, C, Depaigne-Loth, A, Shaw, C, Hammer, A, Ommen, O, Pfaff, H, Groene, O, Botje, D, Wagner, C, Kutaj-Wasikowska, H, Kutryba, B, Escoval, A, Franca, M, Almeman, F, Kus, H, Ozturk, K, Mannion, R, Arah, OA, Chow, A, DerSarkissian, M, Thompson, C, Wang, A, Thompson, A“…Four measures of QM activities at care pathway level focusing on Specialized expertise and responsibility (SER), Evidence-based organization of pathways (EBOP), Patient safety strategies (PSS) and Clinical review (CR). RESULTS: Positive significant associations were found between the three hospitals level QM measures. …”
Publicado 2014
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40092“…The results from pretreatment of microcrystalline cellulose (MCC) showed that (1) pretreatment with acidified alkylene glycol (AG) alone increased enzymatic digestibility compared to pretreatments with acidified alkylene carbonate (AC) alone and acidified mixtures of AC and AG, (2) pretreatment with acidified GC alone slightly increased, but with acidified EC alone significantly decreased, enzymatic digestibility compared to untreated MCC, and (3) there was a good positive linear correlation of enzymatic digestibility of treated and untreated MCC samples with congo red (CR) adsorption capacity. CONCLUSIONS: Acidified GC alone was a more effective solvent for pretreatment of sugarcane bagasse than acidified EC alone. …”
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40093por Peng, Bo, Wang, Lingqiang, Fan, Chuchuan, Jiang, Gonghao, Luo, Lijun, Li, Yibo, He, Yuqing“…The QTL could be detected again and showed dominance (qWBR1, qWBR8, qWBR12, and qCR5) or overdominance effects (qWCR7) for the rate of the white belly or white core, respectively, and all four QTL clusters derived from Zhenshan 97 controlling white belly rate were stably and reliably identified in an F(2) population. …”
Publicado 2014
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40094“…Best response was partial response (PR) in 2/16 patients (12.5%) and clinical benefit (CB), defined as complete response (CR) + PR + stable disease ≥6 months, was observed in 10/16 patients (CB rate (CBR) 62.5%). …”
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40095por Jensen, Janni M, Mose, Frank H, Kulik, Anna-Ewa O, Bech, Jesper N, Fenton, Robert A, Pedersen, Erling B“…The following measurements were performed: urinary concentrations of AQP2 (u-AQP2), NKCC2 (u-NKCC2), ENaC (u-ENaCγ), glomerular filtration rate (GFR) estimated by (51)Cr-EDTA clearance, free water clearance (C(H2O)), urinary output (UO), fractional excretion of sodium (FE(Na)), plasma concentrations of AVP, renin (PRC), Angiotensin II (ANG II), Aldosterone (Aldo) and body fluid volumes. …”
Publicado 2014
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40096“…RESULTS: In patients with a listed medical history of hypertension (n = 1,464), least-squares mean (LSM [standard error (SE)]) changes from baseline to endpoint with placebo, tapentadol ER, and oxycodone HCl controlled release (CR), respectively, were −0.7 (0.44), 0.2 (0.43), and −0.9 (0.45) beats per minute (bpm) for heart rate; −2.4 (0.64), −2.7 (0.64), and −3.7 (0.67) mmHg for SBP; and −1.0 (0.39), −1.3 (0.39), and −2.3 (0.41) mmHg for DBP; in patients with at least one listed concomitant antihypertensive medication (n = 1,376), the LSM (SE) changes from baseline to endpoint were −0.6 (0.45), 0.1 (0.44), and −0.7 (0.47) bpm for heart rate; −1.8 (0.66), −3.3 (0.65), and −3.7 (0.69) mmHg for SBP; and −0.7 (0.40), −1.4 (0.40), and −2.3 (0.42) mmHg for DBP. …”
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40097por Pastore, Friederike, Kling, Daniela, Hoster, Eva, Dufour, Annika, Konstandin, Nikola P, Schneider, Stephanie, Sauerland, Maria C, Berdel, Wolfgang E, Buechner, Thomas, Woermann, Bernhard, Braess, Jan, Hiddemann, Wolfgang, Spiekermann, Karsten“…Both, bi- and moCEBPA-mutated groups had a low early death (d60) rate of 7% and 9%, respectively. Complete remission (CR) rates for biCEBPA- and moCEBPA-mutated patients were 82% vs. 70% (p = 0.17). biCEBPA-mutated patients showed a longer relapse free survival (RFS) (median RFS 9.4 years vs. 1.5 years, p = 0.021) and a lower cumulative incidence of relapse (CIR) compared to moCEBPA-mutated patients. …”
Publicado 2014
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40098“…Sonoclot-analyses showed that activated clotting time (ACT) was unchanged but both clot rate (CR) and platelet function (PF) were higher at T2 compared to T1. …”
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40099por Rutti, Sabine, Arous, Caroline, Schvartz, Domitille, Timper, Katharina, Sanchez, Jean-Charles, Dermitzakis, Emmanouil, Donath, Marc Y., Halban, Philippe A., Bouzakri, Karim“…RESULTS: Both CX3CL1 and its receptor CX3CR1 are expressed in human islets. However, CX3CL1 is more expressed in non-β-cells than in β-cells while its receptor is more expressed in β-cells. …”
Publicado 2014
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40100por King, Will D, Ashbury, Janet E, Taylor, Sherryl A, Tse, M Yat, Pang, Stephen C, Louw, Jacob A, Vanner, Stephen J“…Regardless, this study contributes to a better understanding of the role of global DNA methylation as an early event in CR carcinogenesis with implications for future etiologic research.…”
Publicado 2014
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