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40161por Reboursiere, Emilie, Bras, Fabien Le, Herbaux, Charles, Gyan, Emmanuel, Clavert, Aline, Morschhauser, Franck, Malak, Sandra, Sibon, David, Broussais, Florence, Braun, Thorsten, Fornecker, Luc-Matthieu, Garidi, Reda, Tricot, Sabine, Houot, Roch, Joly, Bertrand, Abarah, Wajed, Choufi, Bachra, Pham, Anne-Dominique, Gac, Anne-Claire, Fruchart, Christophe, Marin, Emilie, Safar, Violaine, Parcelier, Anne, Maisonneuve, Hervé, Bachy, Emmanuel, Cartron, Guillaume, Jaccard, Arnaud, Tournilhac, Olivier, Rossi, Cédric, Schirmer, Luciane, Martignoles, Jean-Alain, Gaulard, Philippe, Tilly, Hervé, Damaj, Gandhi“…Overall response rate (ORR) was 32.6% with complete response (CR) rate of 24.6% and median DoR was 3.3 months (1-39). …”
Publicado 2016
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40162por Howie-Esquivel, Jill, Bibbins-Domingo, Kirsten, Clark, Robyn, Evangelista, Lorraine, Dracup, KathleenEnlace del recurso
Publicado 2014
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40163por Ruisi, Phillip, Makaryus, John N., Catanzaro, John N., Ruisi, Michael, Cedrone, Anthony, Makaryus, Amgad N., Altman, Erik, Jadonath, Ram, Beldner, StuartEnlace del recurso
Publicado 2013
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40165por Wang, Jinyan, Li, Yongrui, Xu, Xuebin, Liang, Beibei, Wu, Fuli, Yang, Xiaoxia, Ma, Qiuxia, Yang, Chaojie, Hu, Xiaofeng, Liu, Hongbo, Li, Hao, Sheng, Chunyu, Xie, Jing, Du, Xinying, Hao, Rongzhang, Qiu, Shaofu, Song, Hongbin“…Of all the 71 isolates with decreased susceptibility to ciprofloxacin, 65 showed at least one mutation (D87Y, D87N, or D87G) in gyrA, among which seven isolates simultaneously had mutations of parC (S80R) (n = 6) or parC (T57S/S80R) (n = 1), while 49 isolates with either zero or one mutation in gyrA contained plasmid-mediated quinolone resistance (PMQR) genes including qnrB, qnrS, and aac(6′)-Ib-cr. Among the 115 cephalosporin-resistant isolates, the most common ESBL gene was bla(CTX-M), followed by bla(TEM-1), bla(OXA-1), and bla(SHV -12). …”
Publicado 2017
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40166por Liu, Xiaobing, Zhang, Yu, Piao, Jianhua, Mao, Deqian, Li, Yajie, Li, Weidong, Yang, Lichen, Yang, Xiaoguang“…The overall reference values of serum trace elements were 131.5 (55.8-265.0 μg/dL for iron (Fe), 195.5 (107.0–362.4) μg/dL for copper (Cu), 74.0 (51.8–111.3) μg/dL for zinc (Zn), 22.3 (14.0–62.0) μg/dL for rubidium (Rb), 72.2 (39.9–111.6) μg/L for selenium (Se), 45.9 (23.8-104.3) μg/L for strontium (Sr), 1.8 (1.2–3.6) μg/L for molybdenum (Mo), 2.4 (1.2–8.4) μg/L for manganese (Mn), 1.9 (0.6–9.0) ng/L for lead (Pb), 1.1 (0.3-5.6) ng/L for arsenic (As), 835.6 (219.8–4287.7) ng/L for chromium (Cr), 337.9 (57.0–1130.0) ng/L for cobalt (Co), 193.2 (23.6–2323.1) ng/L for vanadium (V), and 133.7 (72.1–595.1) ng/L for cadmium (Cd). …”
Publicado 2017
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40167“…Adding oxaliplatin to preoperative chemoradiotherapy can significantly improve the ypCR rate [risk ratio (RR) = 1.208, 95% confidence interval (95% CI): 1.070–1.364, P = 0.002, I(2) = 14.5%], and decrease the preoperative metastasis (RR = 0.494, 95% CI: 0.256–0.954, P = 0.036, I(2) = 53.9%) and local recurrence rate (RR = 0.761, 95% CI: 0.616–0.941, P = 0.012, I(2) = 26.1%). …”
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40168“…RBF and GFR were measured by the renal vein retrograde thermodilution technique and by renal extraction of Cr-EDTA (= filtration fraction), respectively. Renal oxygenation was estimated from the renal oxygen extraction. …”
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40169por Atassi, Nazem, Xu, Maosheng, Triantafyllou, Christina, Keil, Boris, Lawson, Robert, Cernasov, Paul, Ratti, Elena, Long, Christopher J., Paganoni, Sabrina, Murphy, Alyssa, Salibi, Nouha, Seethamraju, Ravi, Rosen, Bruce, Ratai, Eva-Maria“…N-acetylaspartate (NAA) and total NAA (tNA, NAA + NAAG) were decreased by 17% in people with ALS compared to HC (P = 0.004 and P = 0.005, respectively) indicating neuronal injury and/or loss in the precentral gyrus. tNA correlated with disease progression as measured by forced vital capacity (FVC) (P = 0.014; R(ρ) = 0.66) and tNA/tCr correlated with overall functional decline as measured by worsening of the ALS Functional Rating Scale-Revised (ALSFRS-R) (P = 0.004; R(ρ) = -0.74). …”
Publicado 2017
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40170por Kaye, Sanna, Lokki, A. Inkeri, Hanttu, Anna, Nissilä, Eija, Heinonen, Sini, Hakkarainen, Antti, Lundbom, Jesper, Lundbom, Nina, Saarinen, Lilli, Tynninen, Olli, Muniandy, Maheswary, Rissanen, Aila, Kaprio, Jaakko, Meri, Seppo, Pietiläinen, Kirsi H.“…The upregulated genes included C1q, C1s, C2, ficolin-1, factor H, receptors for C3a and C5a (C5aR1), and the iC3b receptor (CR3). While the terminal pathway components C5 and C6 were downregulated, its inhibitor clusterin was upregulated. …”
Publicado 2017
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40171por Quadros, Rolen M., Miura, Hiromi, Harms, Donald W., Akatsuka, Hisako, Sato, Takehito, Aida, Tomomi, Redder, Ronald, Richardson, Guy P., Inagaki, Yutaka, Sakai, Daisuke, Buckley, Shannon M., Seshacharyulu, Parthasarathy, Batra, Surinder K., Behlke, Mark A., Zeiner, Sarah A., Jacobi, Ashley M., Izu, Yayoi, Thoreson, Wallace B., Urness, Lisa D., Mansour, Suzanne L., Ohtsuka, Masato, Gurumurthy, Channabasavaiah B.“…RESULTS: Here we describe Easi-CRISPR (Efficient additions with ssDNA inserts-CRISPR), a targeting strategy in which long single-stranded DNA donors are injected with pre-assembled crRNA + tracrRNA + Cas9 ribonucleoprotein (ctRNP) complexes into mouse zygotes. …”
Publicado 2017
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40172por Wang, Haipeng, Qiu, Liyun, Wang, Guangbin, Gao, Fei, Jia, Haipeng, Zhao, Junyu, Chen, Weibo, Wang, Cuiyan, Zhao, Bin“…The B1 homogeneity, contrast ratio (CR) of cine images, and off-resonance artifacts in cine images between dual-source and single-source RF transmission were assessed in free-breathing and breath-hold groups, respectively. …”
Publicado 2017
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40173por Mazorra, Zaima, Lavastida, Anabel, Concha-Benavente, Fernando, Valdés, Anet, Srivastava, Raghvendra M., García-Bates, Tatiana M., Hechavarría, Esperanza, González, Zuyen, González, Amnely, Lugiollo, Martha, Cuevas, Iván, Frómeta, Carlos, Mestre, Braulio F., Barroso, Maria C., Crombet, Tania, Ferris, Robert L.“…ADCC-induced by nimotuzumab was determined using a (51)Cr release assay. The in vitro effect of nimotuzumab on natural killer (NK) cell activation and dendritic cell (DC) maturation and the in vivo frequency of circulating regulatory T cells (Tregs) and NK cells were assessed by flow cytometry. …”
Publicado 2017
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40174por Baron, Frédéric, Ruggeri, Annalisa, Beohou, Eric, Labopin, Myriam, Mohty, Mohamad, Blaise, Didier, Cornelissen, Jan J, Chevallier, Patrice, Sanz, Guillermo, Petersen, Eefke, Savani, Bipin N, Gluckman, Eliane, Nagler, Arnon“…Inclusion criteria included adult (≥18 years) patients, acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL), complete remission (CR) at the time of transplantation, first single (with a cryopreserved TNC ≥ 2.5 × 10(7)/kg) or double CBT between 2004 and 2014, and RIC conditioning. …”
Publicado 2017
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40175por Anderegg, M. C. J., van der Sluis, P. C., Ruurda, J. P., Gisbertz, S. S., Hulshof, M. C. C. M., van Vulpen, M., Mohammed, N. Haj, van Laarhoven, H. W. M., Wiezer, M. J., Los, M., van Berge Henegouwen, M. I., van Hillegersberg, R.“…The pathologic complete response (pCR) rate was 15.1% after nCRT and 6.9% after pCT. …”
Publicado 2017
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40176por Mohamed, Mostafa, Katz, Alan W., Tejani, Mohamedtaki A., Sharma, Ashwani K., Kashyap, Randeep, Noel, Marcus S., Qiu, Haoming, Hezel, Aram F., Ramaraju, Gopal A., Dokus, M. Katherine, Orloff, Mark S.“…Patients received a total of 79 bridge therapies: SBRT (n = 24), TACE (n = 37), RFA (n = 9), and Y90 (n = 9). Complete response (CR) was 25% for TACE, 8.6% for SBRT, 22% for RFA, and 33% for Y90. …”
Publicado 2015
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40177“…Three Nb(5)Si(3) polymorphs are known, namely αNb(5)Si(3) (tI32 Cr(5)B(3)-type, D8(l)), βNb(5)Si(3) (tI32 W(5)Si(3)-type, D8(m)) and γNb(5)Si(3) (hP16 Mn(5)Si(3)-type, D8(8)). …”
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40178por Bian, Ai-Lin, Hu, Hui-Ying, Rong, Yu-Dong, Wang, Jian, Wang, Jun-Xiong, Zhou, Xin-Zi“…Furthermore, differences in handgrip strength (HG), fat-free mass (FFM), bone mineral content (BMC), plasma albumin (ALB) and serum creatinine (Cr), and body fat content (FAT) in patients between the sarcopenia and non-sarcopenia groups were statistically significant (P < 0.05). …”
Publicado 2017
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40179por Zeng, Xian-Fei, Lu, Dong-Xue, Li, Jun-Min, Tan, Yun, Li, Zhuo, Zhou, Lei, Xi, Zeng-Qian, Zhang, Shu-Miao, Duan, Wei“…The levels of urinary NGAL and cystatin C in the normoalbuminuria group (UACR <30 mg /g•Cr) were elevated compared with the control group, unlike urinary clusterin. …”
Publicado 2017
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40180por Lozev, Ilia, Pidakev, Ivan, Lotti, Torello, Wollina, Uwe, Gianfaldoni, Serena, Lotti, Jacopo, França, Katlein, Batashki, Atanas, Tchernev, Georgi“…Adalimumab is the first biological approved for moderate to severe AI but does not result in stable CR (cure rate). Therefore its use in a neoadjuvant setting is under investigation. …”
Publicado 2017
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