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  1. 40241
    “…Composite response rate (utilizing different weights for PR/CR and SD) may be worth further investigation. TRIAL REGISTRATION: Clinical trials gov, NCT01295827, Registered February 15, 2011; NCT01704287, Registered October 11, 2012; NCT01866319, Registered May 31, 2013. …”
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    Are tumor size changes predictive of survival for checkpoint blockade based immunotherapy in metastatic melanoma?
  2. 40242
    “…Moreover, activation of AMPK suppressed CFA-induced NF-κB p65 translocation from the cytosol to the nucleus in activated macrophages (CD68(+) and CX3CR1(+)) of inflamed skin tissues. Subcutaneous injection of IL-1ra attenuated CFA-induced inflammatory pain. …”
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    AMPK activation attenuates inflammatory pain through inhibiting NF-κB activation and IL-1β expression
  3. 40243
    “…The results indicated that, compared with S-1 alone, the combination of apatinib with S-1 significantly improved patient partial response rate (odds ratio [OR] = 1.91, 95% confidence interval [CI] = 1.21–3.02, P = .005), overall response rate (ORR, OR = 2.40, 95% CI = 1.51–3.82, P = .0002), and disease control rate (DCR, OR = 2.78, 95% CI = 1.51–5.10, P = .0010), whereas the rates of complete response (CR, OR = 2.38, 95% CI = 0.93–6.12, P = .07) and stable disease (SD, OR = 0.99, 95% CI = 0.64–1.54, P = .97) and QoL (OR = 1.22, 95% CI = 0.51–2.92, P = .66) did not differ significantly. …”
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    The combination of apatinib and S-1 for the treatment of advanced gastric cancer in China: A meta-analysis of randomized controlled trials
  4. 40244
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    Preoperative Cardiac Stress Tests Ordered in the Preoperative Evaluation Clinic: A Retrospective Review of Ordering Patterns
  5. 40245
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    Anti-Hypertensive Effect of Sacubitril/Valsartan: A Meta-Analysis of Randomized Controlled Trials
  6. 40246
    “…The markers values at baseline and after 4 cycles were used to analyze the relationship between their variation over baseline and the tumor response, evaluated as disease control rate (DCR: CR + PR + SD), and survival (PFS and OS). RESULTS: A total of 70 patients were evaluable for the analysis. …”
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    The role of CEA, CYFRA21-1 and NSE in monitoring tumor response to Nivolumab in advanced non-small cell lung cancer (NSCLC) patients
  7. 40247
    “…Pathologically complete resection (P-CR) rate was 86.36% (19/22) and 91.67% (11/12) in the LC-EMR and ESD groups (P = 0.646), respectively. …”
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    Endoloop ligation after endoscopic mucosal resection using a transparent cap: A novel method to treat small rectal carcinoid tumors
  8. 40248
    “…The primary outcome is cure rate (CR) against Trichuris trichiura infection as assessed by Kato-Katz 14–21 days after treatment. …”
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    Efficacy and safety of ivermectin and albendazole co-administration in school-aged children and adults infected with Trichuris trichiura: study protocol for a multi-country randomized controlled double-blind trial
  9. 40249
    “…NJH was supported by a CR Roper Research Fellowship. The NHMRC provided salary support (#1136418 to ST #1062418 to TKL, #1064845 to SS). …”
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    Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunction
  10. 40250
    “…Comparative analysis revealed that birds feeding at the wastewater treatment plant carried the greatest resistance gene burden, including genes typically associated with multidrug resistance plasmids as the aac(6)-Ib-cr gene. Differences in resistance gene burden also reflected aspects of bird ecology, taxonomy, and microbial function. …”
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    Meta-transcriptomics reveals a diverse antibiotic resistance gene pool in avian microbiomes
  11. 40251
    “…In addition, surface CX3CR1 decreased upon antigen-loading while HLA-DR+ NK cells maintained a CCR7-, CXCR3(low) homing profile. …”
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    Human Cytomegalovirus Antigen Presentation by HLA-DR+ NKG2C+ Adaptive NK Cells Specifically Activates Polyfunctional Effector Memory CD4+ T Lymphocytes
  12. 40252
    “…Six IB live vaccines were used as control, the reference vaccines represent IBV strains including H120, H52, 4/91, CR88, 233A, and 1-96. Primers XCe2+ and XCe2- were used to amplify S1 gene partially. …”
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    Genetic characterization of S1 gene of infectious bronchitis virus isolated from commercial poultry flocks in West Java, Indonesia
  13. 40253
    “…Glomerular filtration rate (GFR) was estimated using creatinine‐based (eGFR(Cr)) and cystatin C‐based (eGFR(Cys)) regression equations. …”
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    Relative sarcopenia and mortality and the modifying effects of chronic kidney disease and adiposity
  14. 40254
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    Rate Control Yields Better Clinical Outcomes Over a Median Follow-Up of 20 Months Compared to Rhythm Control Strategy in Patients With a History of Atrial Fibrillation: A Retrospective Cohort Study
  15. 40255
    por Wang, Ruiqi, Gao, Xiaoning, Yu, Li
    Publicado 2019
    “…With respect to treatment outcome, TET2 mutation predicted a significantly lower rate of complete remission (CR) in cases with ELN favorable-risk cytogenetics (OR = 0.460, P = 0.011). …”
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    The prognostic impact of tet oncogene family member 2 mutations in patients with acute myeloid leukemia: a systematic-review and meta-analysis
  16. 40256
    “…Group I (control): samples were untreated, group II: grit-blasting with 50 µm alumina particles, group III: grit-blasting with 100 µm alumina particles, group IV: Er,Cr:YSGG laser, and group V: selective infiltration etching technique. …”
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    Effect of different combinations of surface treatment on adhesion of resin composite to zirconia
  17. 40257
    “…Most studies evaluating web-based technology programmes alone or in combination with m-Health also utilised traditional CR, and reported improved modifiable CAD risk factors. …”
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    Modes of e-Health delivery in secondary prevention programmes for patients with coronary artery disease: a systematic review
  18. 40258
    “…RESULTS: In all cases, the TT completely disappeared (CR) in 17 patients (22.7%), 55 patients (73.3%) had a partial response (PR), and 3 patients (4.0%) had a stable disease (SD). …”
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    Hypofractionated radiotherapy as a salvage treatment for recurrent hepatocellular carcinoma with inferior vena cava/right atrium tumor thrombus: a multi-center analysis
  19. 40259
    “…Compared to baseline, the frequency of Gal9(+) CD34(−) cells was significantly higher in patients with treatment failure (TF) than in those in complete remission (CR), and this finding correlated with increased TIM-3 expression on marrow-resident T cells in TF patients. …”
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    Gal9/Tim-3 expression level is higher in AML patients who fail chemotherapy
  20. 40260
    “…Of nine patients treated with curative intent, 44.4% achieved a clinical complete response (CR). Concurrent chemotherapy was administered in 12 patients, with all patients being treated having definitively received chemotherapy. …”
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    Clinical Outcomes of Spatially Fractionated GRID Radiotherapy in the Treatment of Bulky Tumors of the Head and Neck
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