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40321por Liu, PeiYao, Niu, XiaoShuang, Ou, Dan, Qiu, JianJian, Lou, PengRong, Xue, LiangJun, Zhou, Xin, Xu, Tingting, Wang, XiaoShen“…Magnetic resonance imaging studies demonstrated that 10 patients had a complete response (CR), 13 had a partial response, and 3 had stable disease. …”
Publicado 2020
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40322por Blumenau, Sonja, Foddis, Marco, Müller, Susanne, Holtgrewe, Manuel, Bentele, Kajetan, Berchtold, Daniel, Beule, Dieter, Dirnagl, Ulrich, Sassi, Celeste“…Therefore we used Taqman genotyping, exome and RNA sequencing to investigate Alzheimer’s disease known pathogenic variants and pathways: APOE ε4 allele, APP-Aβ metabolism and late-onset Alzheimer’s disease main genome-wide association loci (APOE, BIN1, CD33, MS4A6A, CD2AP, PICALM, CLU, CR1, EPHA1, ABCA7) in 96 early-onset small vessel ischemic disease Caucasian patients and 368 elderly neuropathologically proven controls (HEX database) and in a mouse model of cerebral hypoperfusion. …”
Publicado 2020
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40323por Yoshida, Yui, Kashiwabara, Kosuke, Hirakawa, Yosuke, Tanaka, Tetsuhiro, Noso, Shinsuke, Ikegami, Hiroshi, Ohsugi, Mitsuru, Ueki, Kohjiro, Mita, Tomoya, Watada, Hirotaka, Koya, Daisuke, Mise, Koki, Wada, Jun, Shimizu, Miho, Wada, Takashi, Ito, Yumi, Narita, Ichiei, Kashihara, Naoki, Nangaku, Masaomi, Matsuyama, Yutaka“…We defined DKD as a urinary albumin to creatinine ratio (ACR) ≥30 mg/gCr and/or estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m². …”
Publicado 2020
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40324“…He was found to be acidemic with bicarbonate=16, AG=18, Cr=1.6 (baseline 1.1), lactic acid=2.9, glucose=245, glucosuria/ketonuria, serum osmolality=295, and CPK=3613. …”
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40325por Romeu, Jose, Dodge, Hannah, Mears, Chad, Kozlow, Erin, Patel, Ravi, Vunnam, Rama, Bhatt, Dhirisha, Sahu, Nitasa, Golamari, Reshma, Jain, Rohit“…Her labs were significant for a hyponatremia of 125 mmol/L with an acute kidney injury [AKI] (Cr 1.94 mg/dL from 1.5 mg/dL). Patient was placed initially on a dextrose 5% normal saline infusion, but glucose levels continued to decline after brief response. …”
Publicado 2020
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40326por Takano, Koji, Nishimoto, Keisuke, Yamazaki, Hiroki, Murakami, Koki, Tachi, Tetsuro, Kidani, Tomoki, Kanemura, Yonehiro, Nakajima, Shin, Masuda, Tomohito, Kurusu, Tomomi, Hirota, Kazuyuki, Uechi, Takashi, Watanabe, Dai, Nishida, Yasuharu, Uehira, Tomoko, Fujinaka, Toshiyuki“…Five of the six patients with PCNSL were treated at our hospital, four of which were treated with highly active antiretroviral treatment (HAART) and whole-brain irradiation and one with HAARA alone, resulting four with CR and one with SD. Four patients, except one who had sudden death of unknown cause, were still alive without recurrence (median observation period 44.5 months). …”
Publicado 2019
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40327por Omura, Takaki, Miyakita, Yasuji, Ohno, Makoto, Takahashi, Masamichi, Satomi, Natsuko, Fujimoto, Kenji, Omura, Tomoko, Narita, Yoshitaka“…Use of TTF for 6 months or longer with residual tumor was CR 1 case,PR 1 case,SD 2 cases. Our department policy is to continue for 12 months. …”
Publicado 2019
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40328por Chen, Liting, Xu, Bin, Long, Xiaolu, Gu, Jia, Lou, Yaoyao, Wang, Di, Cao, Yang, Wang, Na, Li, Chunrui, Wang, Gaoxiang, Wang, Ying, Zhu, Li, Wang, Jin, An, Haiyun, Xiao, Min, Xiao, Yi, Zhou, Jianfeng“…Fortunately, a round of fully human monoclonal anti-CD22 CAR T-cell therapy was still effective in this patient, and he achieved CR again and continued to be followed. Each time after infusion, the CAR T-cells underwent extremely rapid exponential expansion, which may be due to the disruption of TP53, a gene that can functionally control cell cycle arrest. …”
Publicado 2020
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40329por Zhao, Xianzhi, Zhu, Xiaofei, Zhuang, Hongqing, Guo, Xueling, Song, Yongchun, Ju, Xiaoping, Wang, Ping, Yuan, Zhiyong, Zhang, Huojun“…The complete response (CR), partial response (PR), stable disease (SD) and progressive disease (PD) rates were 23.8%, 23.8%, 31.0% and 21.4%, respectively. …”
Publicado 2020
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40330por Gridelli, Cesare, Ciuleanu, Tudor, Domine, Manuel, Szczesna, Aleksandra, Bover, Isabel, Cobo, Manuel, Kentepozidis, Nikolaos, Zarogoulidis, Konstantinos, Kalofonos, Charalabos, Kazarnowisz, Andrzej, Korozan, Magdalena, de las Penas, Ramon, Majem, Margarita, Chella, Antonio, Griesinger, Frank, Bournakis, Evangelos, Sadjadian, Parvis, Kotsakis, Athanasios, Chinet, Thierry, Syrigos, Kostantinos N., Correale, Pierpaolo, Gallou, Catherine, Jamet, Jeanne- Menez, Vetsika, Eleni- Kyriaki, Kosmatopoulos, Kostas, Georgoulias, Vassilis“…There was no documented objective CR or PR. Long lasting TERT-specific immune response was observed in 29.2% of vaccinated patients who experienced a significantly longer OS compared to non-responders (21.3 and 13.4 months, respectively; p = 0.004). …”
Publicado 2020
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40331por Takeuchi, Satoshi, Kuroboshi, Haruo, Mori, Taisuke, Ito, Kimihiko, Kondo, Eiji, Tabata, Tsutomu, Itani, Yoshio, Kawaguchi, Ryuji, Takeuchi, Kyosuke, Soejima, Toshinori, Sasaki, Ryohei“…The response rate was 88.2% [9 complete response (CR), 3 partial response (PR), 3 stable disease (SD), 2 not evaluable (NE)]. …”
Publicado 2020
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40332por Luo, Jun, Zheng, Jiaping, Shi, Changsheng, Fang, Jian, Peng, Zhiyi, Huang, Jing, Sun, Junhui, Zhou, Guanhui, Li, Tiefeng, Zhu, Dedong, Xu, Huanhai, Hou, Qinming, Ying, Shihong, Sun, Zhichao, Du, Haijun, Xie, Xiaoxi, Cao, Guohong, Ji, Wenbin, Han, Jun, Gu, Wenjiang, Guo, Xiaohua, Shao, Guoliang, Yu, Zhihai, Zhou, Jian, Yu, Wenqiang, Zhang, Xin, Li, Ling, Hu, Hongjie, Hu, Tingyang, Wu, Xia, Chen, Yutang, Ji, Jiansong, Hu, Wenhao“…Liver function change and adverse events (AEs) were recorded during and after DEB-TACE operation. 3 (8.1%) patients achieved complete response (CR) and 22 (59.5%) patients achieved partial response (PR), with objective response rate (ORR) of 67.6%. …”
Publicado 2020
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40333por Birkedal Glenthoej, Louise, Lise, Mariegaard, Fagerlund, Birgitte, Richardt Jepsen, Jens, Dam Kristensen, Tina, Wenneberg, Christina, Krakauer, Kristine, Medalia, Alice, Roberts, David, Hjorthøj, Carsten, Nordentoft, Merete“…Applying cognitive remediation (CR) before the onset of manifest psychosis may improve cognition and the clinical and functional prognosis of UHR individuals. …”
Publicado 2020
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40334por Zhang, Niubing, Jing, Xinyun, Liu, Yuanhua, Chen, Minjie, Zhu, Xianfeng, Jiang, Jing, Wang, Hongbing, Li, Xuan, Hao, Pei“…The residual activities, however, were completely eliminated with new constructs for persistent crRNA targeting. On the other hand, targeting Cas13a to Tf1 RNA intermediates significantly inhibited Tf1 retrotransposition. …”
Publicado 2020
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40335por Kempthorne, Liam, Yoon, Hyejin, Madore, Charlotte, Smith, Scott, Wszolek, Zbigniew K., Rademakers, Rosa, Kim, Jungsu, Butovsky, Oleg, Dickson, Dennis W.“…In addition, expression of selective and specific microglial markers, including P2RY12, CX3CR1 and CSF-1R, were reduced in affected white matter. …”
Publicado 2020
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40336por Sharma, Esseim, McCauley, Brian, Ghosalkar, Dhairyasheel S., Atalay, Michael, Collins, Scott, Parulkar, Anshul, Sheikh, Wasiq, Ahmed, Malik B., Chu, AntonyEnlace del recurso
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40337por Shaw, Joseph W., Springham, Matthew, Brown, Derrick D., Mattiussi, Adam M., Pedlar, Charles R., Tallent, Jamie“…To calculate s-RPE, the session duration was multiplied by the RPE, measured using the modified Borg CR-10 scale. The Edwards summated heart rate zones (Edwards TRIMP) and Banister training impulse (Banister TRIMP) methods were used as criterion measures of internal TL. …”
Publicado 2020
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40338por Sun, Chi, Hu, Annan, Wang, Shengxing, Tian, Bo, Jiang, Libo, Liang, Yun, Wang, Houlei, Dong, Jian“…The overexpression of CX3CR1 facilitated the spinal metastasis of HCC in a mouse model in vivo. …”
Publicado 2020
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40339“…Resistome analysis identified that A. caviae SCAc2001 carried 13 antimicrobial resistance genes, including β-lactams (bla(KPC), bla(CTX-M-14), bla(TEM-1), bla(OXA-10), bla(OXA-427), bla(VEB-3) and bla(MOX-6)), aminoglycosides (aadA1), fluoroquinolones (aac(6ʹ)-Ib-cr), phenicol resistance (catB3), sulfonamide (sul1), trimethoprim (dfrA5) and colistin resistance (mcr-3.3).And also, A. caviae ScAc2001 carried 54 putative virulence genes including the type IV pilus, fimbria, flagellarthe, and hemolysin A encoding genes, and 12 pathogen–host interactions (PHI) genes. …”
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40340por Chen, Guoliang, Li, Jiachun, Wei, Fuxin, Ji, Qiao, Sui, Wenyuan, Chen, Bailing, Zou, Xuenong, Xu, Zuofeng, Liu, Xizhe, Liu, Shaoyu“…Maximum spinal cord compression (MSCC), compression rate (CR), and IOUSI gray value ratio (R(gray)) were calculated. …”
Publicado 2020
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