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40421por Muhammad, Yahaya, Kani, Yamuna Aminu, Iliya, Sani, Muhammad, Jafaru Bunza, Binji, Abubakar, El-Fulaty Ahmad, Abdurrahman, Kabir, Muhd Bashir, Umar Bindawa, Kabir, Ahmed, Armaya’u“…Levels of antioxidant trace elements (Se, Zn, Mg, Cu and Cr), 8-isoprostaglandin F2 alpha and malondialdehyde in the plasma and erythrocytes activity of glutathione, glutathione peroxidase, superoxide dismutase and catalase were determined. …”
Publicado 2021
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40422por Popa, Laura Ioana, Gheorghe, Irina, Barbu, Ilda Czobor, Surleac, Marius, Paraschiv, Simona, Măruţescu, Luminiţa, Popa, Marcela, Pîrcălăbioru, Graţiela Grădişteanu, Talapan, Daniela, Niţă, Mihai, Streinu-Cercel, Anca, Streinu-Cercel, Adrian, Oţelea, Dan, Chifiriuc, Mariana Carmen“…The strains belonging to this clone harbored multiple acquired AR genes [bla(CTX–M–)(15), bla(OXA–)(48), bla(OXA–)(1), bla(SHV–)(106), bla(TEM–)(150), aac(3)-IIa, aac(6′)-Ib-cr, oqxA10, oqxB17, fosA, catB3, dfrA14, tet(D)] and chromosomal mutations involved in AR (ΔmgrB, ΔompK35, amino acid substitutions in GyrA Ser83Tyr, Asp87Asn, ParC Ser80Tyr). …”
Publicado 2021
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40423por Abdulrachman, Dede, Eurwilaichitr, Lily, Champreda, Verawat, Chantasingh, Duriya, Pootanakit, Kusol“…Specifically, we set up three different guide crRNAs targeting pyrG gene and demonstrated that FnCpf1 was able to induce site-specific double-strand breaks (DSBs) followed by an endogenous non-homologous end-joining (NHEJ) DNA repair pathway which caused insertions or deletions (indels) at these site-specific loci. …”
Publicado 2021
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40424por Cheng, Ke, Fang, Liang-Xing, Ge, Qian-Wen, Wang, Dong, He, Bing, Lu, Jia-Qi, Zhong, Zi-Xing, Wang, Xi-Ran, Yu, Yang, Lian, Xin-Lei, Liao, Xiao-Ping, Sun, Jian, Liu, Ya-Hong“…Consistently, all 11 isolates also possessed bla(CTX–M–)(14), bla(CMY–)(65)(/)(122), aac(6’)-Ib-cr, qnrS1, qnrB13/6/38 and rmtB. These fosA3-positive isolates were assigned to two distinct PFGE patterns and one (n = 9) predominated indicating clonal expansion of fosA3-positive isolates across flower markets and shops. …”
Publicado 2021
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40425por Yuan, Yan, Xiao, Wei-Wei, Xie, Wei-Hao, Cai, Pei-Qiang, Wang, Qiao-Xuan, Chang, Hui, Chen, Bao-Qing, Zhou, Wen-Hao, Zeng, Zhi-Fan, Wu, Xiao-Jun, Liu, Qing, Li, Li-Ren, Zhang, Rong, Gao, Yuan-Hong“…The R0 resection rate, adjusted nonmultivisceral resection rate and bladder preservation rate were 83.0, 43.0 and 83.3%, respectively. The pCR and clinical-downstaging rates were 18, and 81.0%%, respectively. …”
Publicado 2021
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40426por Johnston, Patrick B., Cashen, Amanda F., Nikolinakos, Petros G., Beaven, Anne W., Barta, Stefan Klaus, Bhat, Gajanan, Hasal, Steven J., De Vos, Sven, Oki, Yasuhiro, Deng, Changchun, Foss, Francine M.“…Overall ORR was 86% with 71% reported CR at MTD. Belinostat PK parameters were similar to single-agent. …”
Publicado 2021
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40427“…Having a history of stillbirth 3.646 (AOR: 95% CI: 1.72, 5.65), being informed the term BP/CR from their friends 3.05 (AOR: 95% CI: 1.04, 8.89), being aware of pregnancy danger signs 2.82(AOR: 95% CI: 1.21,6.57) and being aware of two out of four postpartum danger signs 3.571(AOR: 95% CI: 1.511,8.443) were found to be important predictors of birth preparedness and its complication practice. …”
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40428por Valentín-Mazarracin, Irene, Nogaledo-Martín, Miriam, López-de-Uralde-Villanueva, Ibai, Fernández-de-las-Peñas, César, Stokes, María, Arias-Buría, José L., Díaz-Arribas, María J., Plaza-Manzano, Gustavo“…TrA-Contraction Ratio (TrA-CR), TrA-Preferential Activation Ratio (TrA-PAR), and Modified-TrA-PR (M-TrA-PAR) were calculated. …”
Publicado 2021
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40429por Jørgensen, Nicolai Grønne, Kaae, Jeanette, Grauslund, Jacob Handlos, Met, Özcan, Nielsen, Signe Ledou, Pedersen, Ayako Wakatsuki, Svane, Inge Marie, Ehrnrooth, Eva, Andersen, Mads Hald, Zachariae, Claus, Skov, Lone“…Two complete responses (CR) and one PR were observed in eight non-target tumors in four patients. …”
Publicado 2021
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40430por Bitos, Konstantinos, Furian, Michael, Mayer, Laura, Schneider, Simon R., Buenzli, Simone, Mademilov, Maamed Z., Sheraliev, Ulan U., Marazhapov, Nuridin H., Abdraeva, Ainura K., Aidaralieva, Shoira D., Muratbekova, Aybermet M., Sooronbaev, Talant M., Ulrich, Silvia, Bloch, Konrad E.“…At end-exercise, SpO(2) was higher by 2% (95% CI: 2 to 2), and Borg CR10 dyspnea scores were lower by 0.8 points (95% CI: 0.3 to 1.2) compared to LFOT. …”
Publicado 2021
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40431por Guo, Rui, Wan, Feng, Morimatsu, Masatoshi, Xu, Qing, Feng, Tian, Yang, Hang, Gong, Yichen, Ma, Shuhong, Chang, Yun, Zhang, Siyao, Jiang, Youxu, Wang, Heqing, Chang, Dehua, Zhang, Hongjia, Ling, Yunpeng, Lan, Feng“…At the early stage of MI, hUCMSC sheet modulated inflammation by decreasing Mcp1-positive monocytes and CD68-positive macrophages and increasing Cx3cr1-positive non-classical macrophages, preserving the cardiomyocytes from acute injury. …”
Publicado 2021
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40432“…RESULTS: All constructs exhibited an acceptable level of reliability and validity with Cα and CR > 0.7 and AVE > 0.5. An extension of the Unified Theory of Acceptance and Use of Technology Model had good explanatory power for nurses’ behavioral intention of a mobile nursing application. …”
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40433por Schwab, Sebastian, Kleine, Carola Ellen, Bös, Dominik, Bohmann, Sylvie, Strassburg, Christian P., Lutz, Philipp, Woitas, Rainer Peter“…BTP correlated inversely with residual diuresis (r(s) = − 0.58, p < 0.001), residual creatinine clearance (Cl(Cr)) (r(s) = − 0.69, p < 0.001) and total urea clearance (Cl(urea)) (r(s) = − 0.56, p < 0.001). …”
Publicado 2021
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40434por Xu, Jingyan, Xu, Xihui, Chen, Jieyu, Wang, Jing, Jiang, Chong, Lv, Chenglan, Chen, Bing“…INTERVENTIONS: The patient was treated with radiotherapy and six cycles of etoposide, prednisone, vincristine (Oncovin), cyclophosphamide and doxorubicin hydrochloride and achieved complete remission (CR) by PET-CT in August 2010. In November 2014, the patient was diagnosed with relapsed stage IV ENKTL and was treated with six cycles of alternative chemotherapy with the regimen of steroid (dexamethasone), methotrexate, ifosfamide, L-asparaginase, and etoposide and pegaspargase plus Gemcitabine, Oxaliplatin along with radiotherapy. …”
Publicado 2021
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40435por Lambert, Arnaud, Nees, Lotte, Nuyts, Sandra, Clement, Paul, Meulemans, Jeroen, Delaere, Pierre, Vander Poorten, Vincent“…During follow-up, a proportion of CR patients did recur, to reach recurrence-free rates at six months, one year and two years of 60.6%, 48.5% and 32.3%. …”
Publicado 2021
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40436por Kesavan, Murali, Meyrick, Danielle, Gallyamov, Marat, Turner, J. Harvey, Yeo, Sharon, Cardaci, Giuseppe, Lenzo, Nat P.“…Disease control rate (DCR) by PET/CT was 64% (29% SD, 34% PR, and 1% CR). Disease control by PET/CT was associated with an improved one-year overall survival (OS) compared to non-responders, median OS not-reached vs 10-months (p < 0.0001; 95% CI: 0.08–0.44). …”
Publicado 2021
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40437“…Additional resistance genes against quinolones (aac(6′)-Ib-cr, oqxA, oqB), aminoglycoside (aph(3′)-Ia), sulfonamide (sul1), and tetracycline (tet(A)) were also identified. …”
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40438Screening of osteoarthritis diagnostic markers based on immune-related genes and immune infiltrationpor Yuan, Wen-Hua, Xie, Qi-Qi, Wang, Ke-Ping, Shen, Wei, Feng, Xiao-Fei, Liu, Zheng, Shi, Jin-Tao, Zhang, Xiao-Bo, Zhang, Kai, Deng, Ya-Jun, Zhou, Hai-Yu“…The machine learning algorithm cross-identified 15 biomarkers (BTC, PSMD8, TLR3, IL7, APOD, CIITA, IFIH1, CDC42, FGF9, TNFAIP3, CX3CR1, ERAP2, SEMA3D, MPO, and plasma cells). According to pass validation, all 15 biomarkers had high diagnostic efficacy (AUC > 0.7), and the diagnostic efficiency was higher when the 15 biomarkers were fitted into one variable (AUC = 0.758). …”
Publicado 2021
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40439“…A total of 112 PM samples and 21 road dust samples were collected from six stations and one background site in Dhanbad, India from December 2015 to February 2016, and were analyzed for heavy metals (iron (Fe), lead (Pb), cadmium (Cd), nickel (Ni), copper (Cu), chromium (Cr), and zinc (Zn)) using atomic absorption spectrophotometry. …”
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40440por Zhou, Xiaorong, Li, Chenchen, Zhang, Zhao, Li, Daniel Y., Du, Jinwei, Ding, Ping, Meng, Haiyan, Xu, Hui, Li, Ronglei, Ho, Effie, Zhang, Aiguo, Okunieff, Paul, Lu, Jianwei, Sha, Michael Y.“…Notably, cfDNA kinetics (cfDNA Ratio, the ratio of post-chemotherapeutic cfDNA to baseline cfDNA) well distinguished responsive individuals (CR/PR) from the non-responsive (PD/SD). Additionally, cfDNA Ratio was found negatively correlated with PFS in lung adenocarcinoma (LUAD), but not lung squamous-cell carcinoma (LUSC) which may be due to a limited number of LUSC patients in this cohort. …”
Publicado 2021
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