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40481por Fantini, Lorenzo, Belli, Maria Luisa, Azzali, Irene, Loi, Emiliano, Bettinelli, Andrea, Feliciani, Giacomo, Mezzenga, Emilio, Fedeli, Anna, Asioli, Silvia, Paganelli, Giovanni, Sarnelli, Anna, Matteucci, Federica“…Lesions from 15 patients were evaluable and analyzed: 9 with pathological complete response (pCR) and 6 with pathological partial response (pPR). …”
Publicado 2021
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40482“…All samples were analyzed for Cr, Cu, As, Pb, Cd, Co, Ni, Zn, and Hg using the Energy Dispersive X-Ray Florescence (ED-XRF) method. …”
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40483por McKinley, Jennifer M., Mueller, Ute, Atkinson, Peter M., Ofterdinger, Ulrich, Cox, Siobhan F., Doherty, Rory, Fogarty, Damian, Egozcue, J. J., Pawlowsky-Glahn, V.“…Using three alternative regression methods (linear, generalised linear and Tweedie models), the elemental balances of Cr/Ni and As/Mo were found to produce the largest correlation with CKDu. …”
Publicado 2020
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40484“…The complete remission rate (CR) was 22% in the experimental group and 8% in the control group (P=0.04), which was statistically significant. …”
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40485por Vazquez-Vilar, Marta, Garcia-Carpintero, Víctor, Selma, Sara, Bernabé-Orts, Joan M., Sanchez-Vicente, Javier, Salazar-Sarasua, Blanca, Ressa, Arianna, de Paola, Carmine, Ajenjo, María, Quintela, Jose Carlos, Fernández-del-Carmen, Asun, Granell, Antonio, Orzáez, Diego“…Here we present a comprehensive extension of the software-assisted cloning platform GoldenBraid (GB), in which, on top of its multigene cloning software, we integrate new tools for the Type IIS-based easy and rapid assembly of up to six tandemly-arrayed gRNAs with both Cas9 and Cas12a, using the gRNA-tRNA-spaced and the crRNA unspaced approaches, respectively. As stress tests for the new tools, we assembled and used for Agrobacterium-mediated stable transformation a 17 Cas9-gRNAs construct targeting a subset of the Squamosa-Promoter Binding Protein-Like (SPL) gene family in Nicotiana tabacum. …”
Publicado 2021
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40486por Murphy, Brenna M., Hoskin, Tanya L., Degnim, Amy C., Boughey, Judy C., Hieken, Tina J.“…CONCLUSIONS: Among biopsy-proven cN+ NET patients, we observed deescalation of axillary surgery in selected patients, despite a low nodal pathologic complete response (pCR) rate, without nodal recurrences. These data suggest that patients with low-volume axillary disease treated with NET may be managed similarly to patients treated with a surgery-first approach. …”
Publicado 2021
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40487por Kleemann, Johannes, Jäger, Manuel, Valesky, Eva, Kippenberger, Stefan, Kaufmann, Roland, Meissner, Markus“…By the end of the study, three (25%) patients experienced complete remission (CR), four (33%) experienced partial response (PR), two patients (17%) remained at stable disease (SD) and three (25%) patients suffered from progressive disease (PD). …”
Publicado 2021
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40488“…RESULTS: Twenty cases of rGBM were evaluated according to the RANO criteria after treatment with anlotinib and dose-dense TMZ, including five cases of stable disease (SD), thirteen cases of partial response (PR), one case of complete response (CR), and one case of PD. The median follow-up time was 13.4 (95% CI, 10.5–16.3) months. …”
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40489por Di Franco, Simone, Bianca, Paola, Sardina, Davide Stefano, Turdo, Alice, Gaggianesi, Miriam, Veschi, Veronica, Nicotra, Annalisa, Mangiapane, Laura Rosa, Lo Iacono, Melania, Pillitteri, Irene, van Hooff, Sander, Martorana, Federica, Motta, Gianmarco, Gulotta, Eliana, Lentini, Vincenzo Luca, Martorana, Emanuele, Fiori, Micol Eleonora, Vieni, Salvatore, Bongiorno, Maria Rita, Giannone, Giorgio, Giuffrida, Dario, Memeo, Lorenzo, Colarossi, Lorenzo, Mare, Marzia, Vigneri, Paolo, Todaro, Matilde, De Maria, Ruggero, Medema, Jan Paul, Stassi, Giorgio“…Here, we show that IL-6 and HGF, secreted by tumor neighboring visceral adipose stromal cells (V-ASCs), expand the metastatic colorectal (CR) cancer cell compartment (CD44v6 + ), which in turn secretes neurotrophins such as NGF and NT-3, and recruits adipose stem cells within tumor mass. …”
Publicado 2021
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40490por Desai, Amrita, Saul, Eduardo E., Chapman, Jennifer R., Lekakis, Lazaros, Pimentel, Agustin“…Of the seven cases that were evaluable for lymphoma response, four cases (57%) achieved complete response (CR), and three of them (43%) were alive with no evidence of recurrence at 10, 16 and 52 months as of the last contact. …”
Publicado 2020
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40491por Uckun, Fatih M., Lin, Tara L., Mims, Alice S., Patel, Prapti, Lee, Cynthia, Shahidzadeh, Anoush, Shami, Paul J., Cull, Elizabeth, Cogle, Christopher R., Watts, Justin“…Preliminary efficacy signals were observed in both AML and MDS patients: Prolonged stable disease (SD), partial remissions (PR), and complete remissions (CR) were observed in R/R AML patients as best overall responses to APVO436 at the RP2D level. …”
Publicado 2021
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40492Publicado 2021“…Twenty patients obtained CR(46.5%), 18 patients obtained PR, 4 patients were SD, 1 patient was PD. …”
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40493por Eyre, Toby A., Caillard, Sophie, Finel, Herve, Boumendil, Ariane, Kothari, Jaimal, Zimmermann, Heiner, Trappe, Ralf Ulrich, De Wilde, Virginie, Tholouli, Eleni, Kanfer, Edward, Broom, Angus, Damaj, Gandhi, Bargetzi, Mario, Kozák, Tomáš, Hilgendorf, Inken, Crawley, Charles, Kerre, Tessa, Trněný, Marek, Bachy, Emmanuel, Robinson, Stephen, Montoto, Silvia“…Remission status pre-autoSCT was CR 47% and PR 38%. BEAM conditioning was used in 57% and high-dose melphalan in 10%. …”
Publicado 2021
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40494por Pankavec, Sviatlana, Falandysz, Jerzy, Komorowicz, Izabela, Hanć, Anetta, Barałkiewicz, Danuta, Fernandes, Alwyn R.“…The fortification showed some effects on the uptake of other trace minerals, but concentrations of co-accumulated Ag, Al, As, Ba, Cd, Co, Cr, Cs, Cu, Hg, Mn, Ni, Pb, Rb, Sr, Tl, U, V and Zn were similar or lower than values reported in the literature for commercial A. bisporus. …”
Publicado 2021
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40495“…Among the 18.8% of patients who achieved complete response (CR) and partial response (PR), six-month survival rate was 100% and one-year survival rate was 69.2%. …”
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40496por Inoue, Yuko, Tsujino, Kayoko, Sulaiman, Nor Shazrina, Marudai, Mitsuru, Kajihara, Akifumi, Miyazaki, Shuichiro, Sekii, Shuhei, Uezono, Haruka, Ota, Yousuke, Soejima, Toshinori“…One hundred twenty-eight patients who achieved complete response (CR), good partial response (PR), and PR without progression for at least for one year after initial therapy were enrolled in this study. …”
Publicado 2021
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40497por Ragala, Mohammed El Amine, El Hilaly, Jaouad, Amaadour, Lamiae, Omari, Majid, AsriI, Achraf E. L., Atassi, Mariam, Benbrahim, Zineb, Mellas, Nawfel, Rhazi, Karima E. L., Halim, Karima, Zarrouq, Btissame“…The instrument showed sufficient reliability and convergent validity demonstrated by acceptable values of composite reliability (CR =0.93–0.97), and average variance extracted (AVE = 0.66–0.93), respectively. …”
Publicado 2021
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40498por Lim, Hester Gail Y., Fischer, Alexander H., Sung, Sarah, Kang, Sewon, Chien, Anna L.“…Clinical severity (grades 0~4) and subtype (constitutional, post-inflammatory, vascular, shadow effects, or others) were determined. A Konica Minolta CR-400 chromameter was used to obtain colorimetry measurements (L(*)a(*)b(*) values). …”
Publicado 2021
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40499por Venturini, Giulia, Kokona, Despina, Steiner, Beatrice L., Bulla, Emanuele G., Jovanovic, Joel, Zinkernagel, Martin S., Escher, Pascal“…In vivo analysis of Nr2e3(rd7/rd7) Cx3cr1(gfp/+) retinas identified microglial cells within ‘rosettes’ from P21 on. …”
Publicado 2021
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40500por Mahdy, Ahmed, Stradner, Martin, Roessler, Andreas, Brix, Bianca, Lackner, Angelika, Salon, Adam, Goswami, Nandu“…Retinal photos were taken via a CR-2 retinal camera, and retinal microvasculature analysis was carried out. …”
Publicado 2021
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