“…From 2016 to 2021, a prospective clinical trial was conducted, and 510 samples with 6 uncommon subtypes of B-cell lymphoma were enrolled to examine the pharmacokinetic behaviour of rituximab and its impact on clinical outcomes, including complete response (CR), progression-free survival (PFS) and overall survival (OS). …”
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“…Experimental investigations were carried out in four stages, on flat specimens, sized S × H = 75 × 115 mm, cut from sheet metal made of various materials such as steel X5CrNi18-10, PA2 aluminium alloy and PMMA polymethyl methacrylate (plastic). …”
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“…She had an unfavorable prognosis because she responded poorly to chemotherapy and developed a relapse shortly after reaching CR. CONCLUSION: The importance of ZNF384 rearrangements in terms of prognosis remains unclear. …”
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“…CONCLUSION: Among women with early‐stage triple‐negative and HER2+ breast cancers, utilization of NACT increased over time, a trend that correlates with previously reported improved rates of pCR and options post‐neoadjuvant treatment with residual disease. …”
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“…FUNDING: This work is supported by the National Key Research and Development Program of China (2018YFC0910303), National Natural Science Foundation of China (81801592, 82101876), Clinical Research Plan of SHDC (SHDC2020CR4011), Ruijin Hospital Youth Incubation Project (KY2021607) and Shanghai Pujiang Young Rheumatologists Training Program (SPROG202006).…”
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“…METHODS: We established radioresistant (RR), chemoresistant (CR) and radiochemoresistant (RCR) human ESCC cell lines using weekly radiation and/or continuous treatment with increasing doses of chemotherapeutic agent 5-FU. …”
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“…ASA score, Charlson’s comorbidity index, P-POSSUM and CR-POSSUM were assessed. RESULTS: 259 patients were recruited, mean age was 80 years. …”
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“…Quality of life was assessed by the EORTC QLQ-C30 and EORTC QLQ-CR29 questionnaires. Outcomes in patients ≥70 years were compared to a reference group of patients <70 years. …”
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“…After a literature search for calmodulin binding, 11 different neuroinflammatory proteins (TREM2, CD33, PILRA, CR1, MS4A, CLU, ABCA7, EPHA1, ABCA1, CH3L1/YKL-40 and NLRP3) were scanned for calmodulin binding domains using the Calmodulin Target Database. …”
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“…There were more patients with a complete remission (CR) in the HD group than in the LD group (P=.016). …”
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“…These correlation persisted after adjustment for decline in filtration via change in serum creatinine (ΔCr) and biomarkers of cardiac and kidney injury, including N-terminal prohormone of brain natriuretic peptide, cardiac troponin I, creatine kinase-MB, serum creatinine and Cystatin C. …”
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“…Platinum-based therapies have been shown to improve the overall pathologic complete response (pCR), but there is conflicting evidence with regard to their contribution to disease-free survival (DFS) and overall survival (OS), even with the addition of a poly (ADP-ribose) polymerase (PARP) inhibitor. …”
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“…A multifaceted assessment was conducted using enrichment factor (EF), ecological risk (ER), bioconcentration factor (BCF), transmission factor (TF), hazard index (HI), and carcinogenic risk (CR). The results indicate a significant increase in the concentration of all metals in urban farmlands. …”
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“…The pathological complete response (pCR) was 18.8% (6/32) in the nICT group and 43.8% (14/32) in the nCRT group (p = 0.03). …”
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“…The aims of this study were to evaluate the contents on nine metallic trace elements (Fe, Zn, Mn, Co, Cd, Pb, Cu, Ni, Cr) in some major raw foodstuffs including rice, maize, peanut, tomato and dried fish in Burkina Faso and assess the health risk of these elements. …”
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“…The patients with chronic kidney disease (CKD) were defined as having an estimated glomerular filtration rate (eGFR) CKD-EPI Cr-Cystatin C < 60 ml/min/1.73 m(2). CCR was calculated by dividing the serum creatinine level by the cystatin C level measured on the same day. …”
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“…Genes conferring resistance to aminoglycosides, β-lactams, sulfonamides, and tetracyclines were the most frequent antimicrobial resistance genes (ARGs) detected and included those that confer resistance to clinically significant antibiotics (bla(CMY-2), bla(CTX-M), mph(A), erm(B), aac(6’)Ib-cr, and qnrS1). Co-occurrence analyses indicated that multiple ARGs significantly co-occurred with each other, and with metal and biocide resistance genes (MRGs and BRGs). …”
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“…Prediction of pathologic complete response (pCR) based on the mid-treatment/12-week percent change in each metric was estimated by area under the receiver operating characteristic curve (AUC). …”
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“…Bacillary cell-length varied significantly with ATT exposure (mean cell-length increase 0·13 log-µm/day; 95%CrI 0·10–0·16). INTERPRETATION: Pharmacodynamics of MTBBSI treatment can be captured using DMN-Tre microscopy, blood Xpert-ultra and culture. …”
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“…[Formula: see text] was measured using a Chroma Meter CR-400 (Konica Minolta Sensing, Inc., Tokyo). Linear correlation coefficients were calculated between [Formula: see text] and [Formula: see text] and between [Formula: see text] and [Formula: see text] at all wavelengths. …”
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