“…Similarly, carcinogenic health risks from exposure to As and Cr exceeded 1E-05 and 1E-06, respectively, needing a risk reduction plan. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, with the CRISPR/Cas based therapeutics, multiplexing is possible, where different sgRNAs or crRNAs can be guided to more than one target within the same gene thus decreasing the possibility of viral escape mutants. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Pb(2+), Zn(2+), Ni(2+) and Cr(3+) had no effect on RCY (even under conditions in which each metal ion was present in 100-fold molar excess over THP). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The concentration ratio (CR), defined as the ratio of Sr concentration in milk to that in feed under equilibrium conditions, exhibited less variability (1.8 × 10(–2)—5.4 × 10(–2)) among the three categories of cows.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: Cruciate-retaining total knee arthroplasty (CR-TKA) was performed in 8 cadaveric knees. The PCL was partially released and completely resected sequentially while the tibial insert thickness was increased from 10- to 12-mm at 1-mm intervals. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We evaluated dice similarity coefficients (DSC), volume, center of intensity distance (CoI), median and threshold values for VOIs of PET and ratios of total choline (tCho), Gln, Gly, myo-inositol (Ins) to total N-acetylaspartate (tNAA) or total creatine (tCr). (3) Results: We found that Gln and Gly ratios generally resulted in a higher correspondence to PET than tCho. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In terms of renal function indexes, the levels of blood urine nitrogen (BUN), Cr, and β 2-MG in the study group were lower, while the level of eGFR in the study group was higher (P < 0.05). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Zoledronate users were the least likely to discontinue their treatment HR = 0.73 (95%CrI: 0.61, 0.88). Higher rates of compliance were observed in those receiving intravenous treatments. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This also provided a route for amino acids and polyamines biosynthesis, where a clear increase in proline biosynthetic enzymes [e.g., pyrroline-5-carboxylate synthetase (P5CS), ornithine aminotransferase (OAT), Pyrroline-5-carboxylate reductase (P5CR), pyrroline-5-carboxylate dehydrogenase (P5CDH), and proline dehydrogenase (PRODH)] and polyamine metabolic enzymes (e.g., spermine and spermidine synthases, ornithine decarboxylase, and adenosyl methionine decarboxylase) were mainly recorded in C4 young leaves. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…By PCR, 30 of 68 antimicrobial resistance (AMR) genes were identified; the prevalence rate of blaTEM, blaSHV, strA, strB, aadA1, and aac(6′)-Ib-cr was more than 50%. Eleven CTX-M-producing K. pneumoniae were found. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Commercially available coatings for implants include titanium nitride (TiN), titanium niobium nitride (TiNbN), oxidized zirconium (OxZr) and zirconium nitride (ZrN) based coatings, whereas current research is focused not only on these, but also on diamond-like-carbon (DLC), silicon nitride (SiN), chromium nitride (CrN) and tantalum-based coatings (TaN and TaO). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…No significant differences were detected in CR, PR, SD, or AEs between the two groups. Subgroup analysis regarding study type, control group, and treatment order indicated that compared with monotherapy, the combination of SBRT with TACE was associated with an increase in 1- and 2-year OSRs but not in ORR. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The mean neighbourhood P:N ratio was 4.49 (95% credible interval [CrI]: 0.98–11.91), consistent with underdiagnosis of TB, and was most pronounced in informal peri-urban neighbourhoods. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…All APL women achieved complete remission (CR). Collectively, ATO and its metabolites can easily cross the placenta. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The IPCR amplicons were cloned into a pCR-XL-2-TOP vector, screened, and sequenced. Out of 40 IPCR amplicons, we confirmed and verified the genetic contexts of 11 samples amplified with primers targeting integron gene cassettes (GCs), IS431 composite transposons, and Tn916 conjugative transposons (tet(M) and xis-int). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Enrichment factor (EF), correlation analyses, and principal component analysis showed that aluminum (Al), cobalt (Co), chromium (Cr), iron (Fe), manganese (Mn), nickel (Ni), titanium (Ti), and zinc (Zn) had mainly the lithogenic occurrence (EF < 2). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Finally, genetic cell ablation of Pax7(Cr)(e)-marked cells is sufficient to cause outflow tract defects in hypomorphs expressing only 10% Pax3, confirming that ectopic and induced Pax7 can play an overlapping functional genetic compensational role in both cardiac neural crest lineage and during craniofacial development, which is normally masked by the dominant role of Pax3.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Immunohistochemically, the tumor cells were positive for syn, CR, CgA, and vasopressin and were focally positive for NeuN, TTF-1, NF, CK8, vimentin, and S100 proteins. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Effective concentration 50 (EC(50)), minimum inhibitory concentration (MIC), and cross-heavy metal resistance pattern were observed at 5.56 mm, 20 mm, and Ni > Zn > Cr > Pb > Ag > Hg, respectively. Biosorption of Cu by live and dead bacterial cells in its presence and inhibitors 1 and 2 (DNP and DCCD) was suggestive of an ATP-independent efflux system. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: In a cohort of 44 patients we performed 3D-segmentation of solid, cystic and whole tumor within our PACS-framework and compared results to previously carried-out central imaging review by RANO criteria which had yielded 15 PD, 27 SD, 2 PR and 0 CR. RESULTS: 8 tumors were solid only and 36 had a mixed solid-cystic appearance. …”
Enlace del recurso
Enlace del recurso