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  1. 40621
    “…The investigation was to reduce the NOx and PM emissions using combustion simulation comparing with each piston of a single-cylinder engine at a CR of 24, 4-stroke, and water-cooled Engine. The four piston bowl shapes of DSEVL2 BMW M47T, Shallow Hesselman, Lombardini 15LD350, and DOOSANP158FE were analyzed by the Diesel-RK combustion simulation. …”
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    Numerical study of different shape design of piston bowl for diesel engine combustion in a light duty single-cylinder engine
  2. 40622
    “…METHODS: This multicenter RW study aims at investigating median time to treatment discontinuation (mTTD), overall survival (mOS) of nivolumab in pretreated patients with NSCLC both from AHF and CR; clinical-pathological features predictive of early treatment discontinuation (etd), budget impact (BI), and cost-effectiveness analysis were investigated; mOS in patients receiving nivolumab and docetaxel was assessed. …”
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    Multicenter Real-World Study on Effectiveness and Early Discontinuation Predictors in Patients With Non-small Cell Lung Cancer Receiving Nivolumab
  3. 40623
    “…Here we focused on the capture of wastewater-associated viruses including Influenza A and B (Flu-A & B), SARS-CoV-2, human adenovirus (AdV), norovirus GII (NoVGII), measles virus (MeV), pepper mild mottle virus (PMMoV), the faecal marker crAssphage and the process control virus Pseudomonas virus phi6. …”
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    Assessment of two types of passive sampler for the efficient recovery of SARS-CoV-2 and other viruses from wastewater
  4. 40624
    por Jensen, Haley, Room-alafox, Maria
    Publicado 2022
    “…Dietitians were randomized to one of three case studies with identical lab values (NA 130, BUN 31, CR 1.9, Blood glucose 475, A1c 9.1) except for the patient's BMI (23.8, 28.9, 31.6) and answered questions about intuitive eating outcome expectations. …”
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    Registered Dietitians’ Perspectives on Intuitive Eating, Care and Treatment
  5. 40625
    “…Of note, patients with lower CXCL13 expression showed a worse prognosis and the CR/PR group had a higher expression of CXCL13 in two immunotherapy treated cohorts. …”
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    Identification of CD8(+) T Cell Related Biomarkers in Ovarian Cancer
  6. 40626
    “…None of the patients achieved complete response (CR); however, 9 patients showed partial response (PR), and 3 patients underwent conversion surgery. …”
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    Long-term Survival, Tolerability, and Safety of First-Line Bevacizumab and FOLFIRI in Combination With Ginsenoside-Modified Nanostructured Lipid Carrier Containing Curcumin in Patients With Unresectable Metastatic Colorectal Cancer
  7. 40627
    “…Postoperative pathology revealed a major pathological response (MPR) in 9 cases (9/13, 69.2%) and a pathological complete response (pCR) in 6 cases (6/13, 46.2%). Five patients (5/18, 27.8%) experienced serious treatment-related adverse events (AEs) of grades 3–4. …”
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    Neoadjuvant Pembrolizumab and Chemotherapy in Resectable Esophageal Cancer: An Open-Label, Single-Arm Study (PEN-ICE)
  8. 40628
    por Dada, Oyeyemi A., Kutu, Funso R.
    Publicado 2021
    “…The results showed that uptake concentration was in the order K(+) > HPO(4)(2−) > Mg(+2) > Ca(2+) > Fe(2+) > Cr(6+) > Zn(2+) > Mn(2+)  > Cu(2+)(mg/kg). Uptake concentration of metalloids: Al and Pd was significantly higher in the unamended. …”
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    Bioavailability and health risk assessment of potentially toxic elements in popcorn kernel from sandy loam Ferric Luvisol amended with municipal solid waste compost
  9. 40629
    “…ETHICS AND DISSEMINATION: The study protocol was reviewed and approved by the Institutional Review Board (IRB) of Daegu Catholic University Medical Center (IRB no. CR-21-082-L, 14 July 2021). The study findings will be published in peer-reviewed journals. …”
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    Impact of a pharmaceutical care service for patients with rheumatoid arthritis using a customised mobile device (the PROUD trial): study protocol for a randomised controlled trial
  10. 40630
    “…In total, 63 participants took aspirin 81 mg daily plus zileuton (Zyflo CR) 600 mg BID or the placebo for 12 weeks. Nasal brushes from the baseline, end-of-intervention, and one-week post intervention were profiled via microarray. …”
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    Clinical Study of Aspirin and Zileuton on Biomarkers of Tobacco-Related Carcinogenesis in Current Smokers
  11. 40631
    por Rostami, Kamran, Ensari, Arzu, Marsh, Michael N., Srivastava, Amitabh, Villanacci, Vincenzo, Carroccio, Antonio, Asadzadeh Aghdaei, Hamid, Bai, Julio C., Bassotti, Gabrio, Becheanu, Gabriel, Bell, Phoenix, Di Bella, Camillo, Bozzola, Anna Maria, Cadei, Moris, Casella, Giovanni, Catassi, Carlo, Ciacci, Carolina, Apostol Ciobanu, Delia Gabriela, Cross, Simon S., Danciu, Mihai, Das, Prasenjit, Del Sordo, Rachele, Drage, Michael, Elli, Luca, Fasano, Alessio, Florena, Ada Maria, Fusco, Nicola, Going, James J., Guandalini, Stefano, Hagen, Catherine E., Hayman, David T. S., Ishaq, Sauid, Jericho, Hilary, Johncilla, Melanie, Johnson, Matt, Kaukinen, Katri, Levene, Adam, Liptrot, Sarah, Lu, Laura, Makharia, Govind K., Mathews, Sherly, Mazzarella, Giuseppe, Maxim, Roxana, La Win Myint, Khun, Mohaghegh-Shalmani, Hamid, Moradi, Afshin, Mulder, Chris J. J., Ray, Ronnie, Ricci, Chiara, Rostami-Nejad, Mohammad, Sapone, Anna, Sanders, David S., Taavela, Juha, Volta, Umberto, Walker, Marjorie, Derakhshan, Mohammad
    Publicado 2022
    “…Villus height (VH, in μm), crypt depth (CrD, in μm), villus-to-crypt ratios (VCR), IELs (intraepithelial lymphocytes/100 enterocytes), and other relevant histological, serologic, and demographic parameters were quantified. …”
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    Gluten Induces Subtle Histological Changes in Duodenal Mucosa of Patients with Non-Coeliac Gluten Sensitivity: A Multicentre Study
  12. 40632
    “…GABA + signal was analyzed relative to water and total creatine (Cr) levels as a function of binge drinking history and sex. …”
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    Cortical GABA levels are reduced in young adult binge drinkers: Association with recent alcohol consumption and sex
  13. 40633
    “…By applying the PSP method, the Pb-free HOIPs with optimal bandgaps were successfully designed from a generated chemical space comprising over 8.20 × 10(18) combinations, which included 733848 candidates (e.g., Cs(0.334)FA(0.266)MA(0.400)Sn(0.769)Ge(0.003)Pd(0.228)Br(0.164)I(2.836)) with an optimal bandgap of 1.34 eV for single junction solar cells, 1511073 large-bandgap candidates (e.g., Cs(0.392)FA(0.016)MA(0.592)Cr(0.383)Sr(0.347)Sn(0.270)Br(1.171)I(1.829)) for top parts in tandem solar cells (TSCs), and 20242 low-bandgap ones (e.g., MA(0.815)FA(0.185)Sn(0.927)Ge(0.073)I(3)) for bottom cells in TSCs. …”
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    Inverse Design of Hybrid Organic–Inorganic Perovskites with Suitable Bandgaps via Proactive Searching Progress
  14. 40634
    “…Both overall survival and progression-free survival were better in subjects who presented complete responses (CR) to HCC treatment. In patients undergoing a single intervention, the best overall survival was associated with surgical resection and RFA. …”
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    Multimodal Treatment of Hepatocellular Carcinoma in Patients With Hepatitis C Virus Infection Treated With Direct-Acting Antivirals
  15. 40635
    por NAKAMURA, Eizo, KOBAYASHI, Katsura, TANAKA, Ryoji, KUNIHIRO, Tak, KITAGAWA, Hiroshi, POTISZIL, Christian, OTA, Tsutomu, SAKAGUCHI, Chie, YAMANAKA, Masahiro, RATNAYAKE, Dilan M., TRIPATHI, Havishk, KUMAR, Rahul, AVRAMESCU, Maya-Liliana, TSUCHIDA, Hidehisa, YACHI, Yusuke, MIURA, Hitoshi, ABE, Masanao, FUKAI, Ryota, FURUYA, Shizuho, HATAKEDA, Kentaro, HAYASHI, Tasuku, HITOMI, Yuya, KUMAGAI, Kazuya, MIYAZAKI, Akiko, NAKATO, Aiko, NISHIMURA, Masahiro, OKADA, Tatsuaki, SOEJIMA, Hiromichi, SUGITA, Seiji, SUZUKI, Ayako, USUI, Tomohiro, YADA, Toru, YAMAMOTO, Daiki, YOGATA, Kasumi, YOSHITAKE, Miwa, ARAKAWA, Masahiko, FUJII, Atsushi, HAYAKAWA, Masahiko, HIRATA, Naoyuki, HIRATA, Naru, HONDA, Rie, HONDA, Chikatoshi, HOSODA, Satoshi, IIJIMA, Yu-ichi, IKEDA, Hitoshi, ISHIGURO, Masateru, ISHIHARA, Yoshiaki, IWATA, Takahiro, KAWAHARA, Kosuke, KIKUCHI, Shota, KITAZATO, Kohei, MATSUMOTO, Koji, MATSUOKA, Moe, MICHIKAMI, Tatsuhiro, MIMASU, Yuya, MIURA, Akira, MOROTA, Tomokatsu, NAKAZAWA, Satoru, NAMIKI, Noriyuki, NODA, Hirotomo, NOGUCHI, Rina, OGAWA, Naoko, OGAWA, Kazunori, OKAMOTO, Chisato, ONO, Go, OZAKI, Masanobu, SAIKI, Takanao, SAKATANI, Naoya, SAWADA, Hirotaka, SENSHU, Hiroki, SHIMAKI, Yuri, SHIRAI, Kei, TAKEI, Yuto, TAKEUCHI, Hiroshi, TANAKA, Satoshi, TATSUMI, Eri, TERUI, Fuyuto, TSUKIZAKI, Ryudo, WADA, Koji, YAMADA, Manabu, YAMADA, Tetsuya, YAMAMOTO, Yukio, YANO, Hajime, YOKOTA, Yasuhiro, YOSHIHARA, Keisuke, YOSHIKAWA, Makoto, YOSHIKAWA, Kent, FUJIMOTO, Masaki, WATANABE, Sei-ichiro, TSUDA, Yuichi
    Publicado 2022
    “…Bulk Ryugu particles show higher δ(18)O, Δ(17)O, and ε(54)Cr values than CI chondrites. As such, Ryugu sampled the most primitive and least-thermally processed protosolar nebula reservoirs. …”
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    On the origin and evolution of the asteroid Ryugu: A comprehensive geochemical perspective
  16. 40636
    “…Over 90% of the hiMGLs expressed microglia-specific markers, such as CX3CR1 and IBA-1. Whole-transcriptome analysis revealed that these hiMGLs are similar to human primary microglia but differ from monocytes/macrophages. …”
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    Single transcription factor efficiently leads human induced pluripotent stem cells to functional microglia
  17. 40637
    “…Selected targets were the β-lactamases SHV, TEM, OXA-1-like, CTX-M-1-like, CMY-2-like, chromosomal E. coli AmpC (cAmpC), OXA-48-like, NDM, VIM, and KPC; the aminoglycoside-modifying enzymes AAC(3)-Ia, AAC(3)-II, AAC(3)-IV, AAC(3)-VI, AAC(6′)-Ib, ANT(2 [Formula: see text])-I, and APH(3′)-VI; the 16S-RMTases ArmA, RmtB, RmtC, and RmtF; the quinolone resistance mechanisms QnrA, QnrB, AAC(6′)-Ib-cr; the wildtype quinolone resistance determining region of GyrA; and the E. coli porins OmpC and OmpF. …”
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    Using Targeted Liquid Chromatography-Tandem Mass Spectrometry to Rapidly Detect β-Lactam, Aminoglycoside, and Fluoroquinolone Resistance Mechanisms in Blood Cultures Growing E. coli or K. pneumoniae
  18. 40638
    “…In vivo, GAS6-AS2 down-regulation decreased urinary NGAL and Kim-1 levels and serum sCr and BUN levels, and H&E proved that the kidney injury was alleviated. …”
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    Suppression of lncRNA GAS6-AS2 alleviates sepsis-related acute kidney injury through regulating the miR-136-5p/OXSR1 axis in vitro and in vivo
  19. 40639
    “…Susceptibility to fluoroquinolones, cefepime, piperacillin-tazobactam, and carbapenems was 49%, 84%, 88%, and 96%, respectively, among GN isolates. Critical illness (CrI), defined as a new requirement for mechanical ventilation, vasopressor, or death within 30 days, occurred in 15% and did not correlate with fluoroquinolone prophylaxis, organism type, initial antibiotics, or adequacy of coverage. …”
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    Bloodstream Infections in Hematologic Malignancy Patients With Fever and Neutropenia: Are Empirical Antibiotic Therapies in the United States Still Effective?
  20. 40640
    “…Classical and non-classical monocytes constitute the major inflammatory cell types, and pro-inflammatory genes such as CCL5, TLR7, and CX3CR1 were significantly upregulated in patients with plaque rupture, while the neutrophil activation and degranulation genes FPR2, MMP9, and CLEC4D were significantly expressed in the intermediate monocytes derived from patients without plaque rupture. …”
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    Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Acute Myocardial Infarction
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