“…The recipients were observed until 10 hours after reperfusion, which included GFR measured as clearance of chrom-51-ethylendiamintetraacetat ((51)Cr-EDTA), animal weight, and renal tissue oxygenation by fiber optic probes. …”
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“…In addition, a higher proportion of PD-1 + Tim-3 + CD3+ T cells in the BM and PD-1 + Tim-3 + CD4+ T cells in PB was detected in non-complete remission (NCR) compared with complete remission (CR) patients after first-cycle chemotherapy. CONCLUSIONS: Upregulation of PD-1 and Tim-3 and the exhausted phenotype of CD4+ and CD8+ T cells in the BM of AML patients may contribute to mediating the leukemic immunosuppressive microenvironment, and increased PD-1 + Tim-3+ CD8+ T cells may be related to T cell dysfunction in AML, which may influence clinical outcome.…”
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“…Stepwise Cox regression analyses revealed that creatinine clearance (CrCl) (<50 mL/min), hepatic impairment, and hypertension were specific predictors for major bleeding and no specific predictors were found for stroke/non-CNS SE/MI in patients aged ≥ 75 years. …”
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“…The BLAST search was performed using sequence databases at NCBI, CR-EST, and TREP and Ensembl Plants databases. Comparison to MAR/SAR sequences was performed using http://smartdb.bioinf.med.uni-goettingen.de/cgi-bin/SMARtDB/smar.cgi database. …”
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“…RESULTS: Sarcopenia subjects had higher baPWV, nutrition risk and lower appendicular skeletal muscle index (ASMI), Handgrip strength (HS), GS, body mass index (BMI), triacylglycerol (TG), serum albumin (ALB) and creatinine (Cr) than did non-sarcopenia subjects; Sarcopenia subjects also had higher visceral fat area (VFA) than did non-sarcopenia subjects (p < 0.05). …”
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“…The cytotoxicity against chicken red blood cells was reduced in the PRV-infected AM as compared to noninfected cells, particularly in AM infected with virulent PRV strains. Specific (51)Cr release values for AM infected with S-62 and 4892 strains were 14 and 19, while the noninfected AM had values of 36. …”
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“…PURPOSE: The association between pathological complete response (pCR) in patients receiving neoadjuvant chemotherapy (NAC) for breast cancer and Circulating Tumour Cells (CTCs) is not clear. …”
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“…Strain number 1 was found 100% identical to Klebsiella pneumoniae subsp. pneumoniae HS11286 according to the outcomes of complete genome sequence analysis, and the strain carried the genes bla(OXA-181), bla(CTXM-15), blaNDM, arr-3, aac (6′)-Ib-cr, rmtF, and catB1. CONCLUSION: Using double carbapenem antibiotics with colistin could be a potential alternative to treat colistin and carbapenem-resistant K. pneumoniae. …”
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“…CD11b is highly expressed on myeloid cells, including TAMs, where it forms a heterodimeric integrin receptor with CD18 (known as CD11b/CD18, Mac-1, CR3, and αMβ2), and plays an important role in recruitment and biological functions of these cells, and is a validated therapeutic target. …”
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“…Different materials (PEEK, Ti-6Al-4V, CoCrMo) for the liner were also evaluated. RESULTS: The traditional ACLR resulted in concentrated stress on the graft where it contacted the tunnel entrance. …”
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“…The genes SdeB/HasF and SdeY/HasF that are associated with efflux pump mediated drug extrusion to fluoroquinolones and tigecycline, respectively, were found in 88.9%. The aac(6′)-Ib-cr variant gene that can simultaneously induce resistance to aminoglycoside and fluoroquinolone was present in 24.1% of the isolates. …”
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“…On the basis of the canopy raw spectral reflectance data and their subsequent transformation by two different techniques, first-derivative reflectance (FDR) and continuum removal (CR), four multivariate regression methods were comparatively analyzed and used to develop predictive models for estimating leaf N concentration: multiple linear regression (MLR), principal component regression (PCR), partial least square (PLS), and support vector machine (SVM). …”
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“…Four independent risk factors were confirmed by the multivariate analysis: patient age ≥45 years old, CR2 or NR before transplantation, a history of extramedullary infiltration and the occurrence of grade Ⅲ–Ⅳ aGVHD. …”
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“…Monosomy1q21 amplification/gain was only seen in 3(8.6%) patients, the other 32 patients were with additional cytogenetic abnormalities including 13q14 deletion, t(11,14), t(4,14), t(14,16), 17p deletion and complex karyotype aberrations. ②The complete remission (CR) rate was 57.0% (20/35), the very good partial remission(VGPR) rate was 37.1%(13/35) and the partial remission (PR) rate was 5.7%(2/35) after ASCT. …”
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“…RESULTS: The overall response rate (ORR) after ASCT was 100.0%, in which the complete remission (CR) was 64.1% and the best treatment response rate of superior to PR was 89.4%. …”
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“…The overall response rate (ORR) was 58.9% (33/56), among which 8.9% was complete response (CR), 19.8% was very good partial response (VGPR), and 30.4% was partial response (PR). …”
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“…With the median follow-up of 9 months, the one PCL patient achieved partial response (PR), progress free survival (PFS) for 6 months and the overall survival (OS) for 21 months; in the cohort of 6 SCL patients cardiac involved at diagnosis, complete response (CR) was achieved in 1 case (16.7%), PR in 3 cases, progressing disease (PD) in 2 cases, with the median PFS for 5 months and the median OS for 19 months; and for the other 3 SCL patients cardiac involved at progression, PR was achieved in 2 case and death in 1 case, with the median PFS for 4 months and the median OS unavailable because of censored data. …”
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“…Subgroup prognostic analysis showed a lower CR rate (P=0.001) and a higher RR (P=0.023) in CD7(+) group comparing to those of CD7(−) group in AML patients with wild type CEBPA. …”
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“…The treatment response was evaluated based on complete response (CR), partial response (PR), and no change (NC), and the cumulative relapse rate and adverse events in each treatment group were compared using Kaplan–Meier curves and log-rank test, respectively. …”
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“…All the frequencies of CD34(+)CD38(−), CD34(+)CD38(−)CD123(+), CD34(+)CD38(−)CD96(+) and CD34(+) CD38(−)TIM-3(+)cells had no impact on the achievement of CR after the first course of induction. All higher frequencies of CD34(+)CD38(−), CD34(+)CD38(−)CD123(+), CD34(+)CD38(−)CD96(+) cells were related to higher 2-year CIR rate. …”
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