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41121por Hao, Shengyu, Jiang, Pan, Xie, Liang, Xiang, Guiling, Liu, Zilong, Hu, Weiping, Wu, Qinhan, Jiang, Liyan, Xiao, Yi, Li, Shanqun“…Construction and analysis of the PPI network showed that CXCL10, CXCL9, CCR1, CX3CR1, CX3CL1, CXCR2, CXCR1, PF4, CCL4L1, and ADORA3 were recognized as top 10 hub genes with high connectivity degrees. …”
Publicado 2021
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41122por Soleimani, Neda, Azadi, Amir, Esmaeili, Mohammad Javad, Ghodsi, Fatemeh, Ghahramani, Reza, Hafezi, Azadeh, Hosseyni, Tayebeh, Arabzadeh, Arezoo, khajeh, Samira, Farhadi, Mahsa, Mohammadzadeh, Sahand“…MATERIALS AND METHODS: In this cross-sectional study, all repeated tests for 26 biochemical analytes (i.e., albumin, alkaline phosphatase (ALP), alanine aminotransferase (ALT), amylase, aspartate aminotransferase (AST), bilirubin total (BT), bilirubin direct (BD), blood urea nitrogen (BUN), calcium, chloride (Cl), cholesterol total (CholT), creatine kinase (CK), creatinine (Cr), glucose, gamma-glutamyl transferase (GGT), high-density lipoprotein-cholesterol (HDL-c), iron, lactate dehydrogenase (LDH), LDL-c, lipase, magnesium (Mg), phosphorus (Ph), protein total (ProtT), total iron binding capacity (TIBC), triglyceride (TG), and uric acid) were assessed in both critical and noncritical ranges over two consecutive months (routine subjective test repeats in the first month and rule-based repeats in the second month). …”
Publicado 2021
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41123por Abi-Jaoudeh, Nadine, Dayyani, Farshid, Chen, Pei Jer, Fernando, Dayantha, Fidelman, Nicholas, Javan, Hanna, Liang, Po-Chin, Hwang, Jen-I, Imagawa, David K“…Sixty percent (95% CI=38.7–78.9) achieved complete response (CR), and 84% (95% CI=63.9–95.5) had complete and partial response per mRECIST for target lesions. …”
Publicado 2021
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41124por Thong, Melissa S. Y., Jansen, Lina, Chang-Claude, Jenny, Hoffmeister, Michael, Brenner, Hermann, Arndt, Volker“…At 5-year follow-up, patients completed assessments on HRQOL (EORTC QLQ-C30 and EORTC QLQ-CR29) and psychological well-being (distress and disease/treatment burden). …”
Publicado 2020
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41125por Rasche, Mareike, Zimmermann, Martin, Steidel, Emma, Alonzo, Todd, Aplenc, Richard, Bourquin, Jean-Pierre, Boztug, Heidrun, Cooper, Todd, Gamis, Alan S., Gerbing, Robert B., Janotova, Iveta, Klusmann, Jan-Henning, Lehrnbecher, Thomas, Mühlegger, Nora, Neuhoff, Nils v., Niktoreh, Naghmeh, Sramkova, Lucie, Stary, Jan, Waack, Katharina, Walter, Christiane, Creutzig, Ursula, Dworzak, Michael, Kaspers, Gertjan, Kolb, Edward Anders, Reinhardt, Dirk“…In the BFM dataset, there was no difference in OS for patients who had a complete remission with full hematopoietic recovery (CR) following post-relapse re-induction compared to those with partial neutrophil and platelet recovery (CRp and CRi) only (52 ± 7% vs. 63 ± 10%, p = 0.39). …”
Publicado 2021
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41126por van Veenendaal, Nicole R., Auxier, Jennifer N., van der Schoor, Sophie R. D., Franck, Linda S., Stelwagen, Mireille A., de Groof, Femke, van Goudoever, Johannes B., Eekhout, Iris E., de Vet, Henrica C. W., Axelin, Anna, van Kempen, Anne A. M. W.“…For internal consistency we calculated composite reliability (CR). We performed multiple imputations by chained equations for missing data. …”
Publicado 2021
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41127por Ye, Zaisheng, Zeng, Yi, Wei, Shenghong, Wang, Yi, Lin, Zhitao, Chen, Shu, Wang, Zhiwei, Chen, Shanshan, Chen, Luchuan“…One patient achieved complete response (CR, 2.7%), 26 patients achieved partial response (PR, 70.3%), three patients had stable disease (SD, 8.1%) and seven patients had progressive disease (PD, 18.9%). …”
Publicado 2021
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41128por Sewunet, Tsegaye, Asrat, Daniel, Woldeamanuel, Yimtubezinash, Ny, Sofia, Westerlund, Fredrik, Aseffa, Abraham, Giske, Christian G“…Resistance genes for aminoglycosides and/or fluoroquinolones [aac(6′)-Ib-cr (65.1%)], phenicols [catB3 (28.4%)], sulphonamides [sul1 (61.2%) and sul2 (60.5%)], trimethoprim [dfrA27 (32.1%)], macrolides [mph(A) (12.8%)] and rifampicin [arr2/arr3 (39.4%)] were prevalent. …”
Publicado 2021
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41129por Zheng, Li-wei, Ma, Sheng-jie, Zhou, Ting, Yue, Cai-peng, Hua, Ying-peng, Huang, Jin-yong“…RESULTS: In this study, a total of 536 BBXs were identified from nine brassicaceae species, including 32 AtBBXs, 66 BnaBBXs, 41 BoBBXs, 43 BrBBXs, 26 CrBBXs, 81 CsBBXs, 52 BnBBXs, 93 BjBBXs, and 102 BcBBXs. …”
Publicado 2021
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41130“…The complete pathological response (pCR) rates in the SC group and LC group were, 25% versus 18.1% (the difference was not statistically significant, P = 0.375), respectively. …”
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41131por Lin, Ruoyi, Zheng, Jiexuan, Pu, Lin, Wang, Zhengfeng, Mei, Qiming, Zhang, Mei, Jian, Shuguang“…Furthermore, one of PIP1 gene, CrPIP1;5, was identified as functional using a yeast expression system and transgenic overexpression in Arabidopsis. …”
Publicado 2021
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41132por Fredua-Agyeman, Rudolph, Hwang, Sheau-Fang, Zhang, Hui, Falak, Igor, Huang, Xiuqiang, Strelkov, Stephen E.“…However, the susceptibility of ‘Tosca’ to most of the common virulent pathotypes makes it unattractive as a sole CR donor in the breeding of commercial canola varieties in western Canada.…”
Publicado 2021
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41133por Dierks, Christine, Seufert, Jochen, Aumann, Konrad, Ruf, Juri, Klein, Claudius, Kiefer, Selina, Rassner, Michael, Boerries, Melanie, Zielke, Andreas, la Rosee, Paul, Meyer, Philipp Tobias, Kroiss, Matthias, Weißenberger, Christian, Schumacher, Tilmann, Metzger, Patrick, Weiss, Harald, Smaxwil, Constantin, Laubner, Katharina, Duyster, Justus, von Bubnoff, Nikolas, Miething, Cornelius, Thomusch, Oliver“…Results: Best overall response (BOR) within ATCs was 66% complete remissions (4/6 CR), 16% stable disease (1/6 SD), and 16% progressive disease (1/6 PD). …”
Publicado 2021
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41134por Jabborova, Dilfuza, Choudhary, Ravish, Karunakaran, Rohini, Ercisli, Sezai, Ahlawat, Jyoti, Sulaymanov, Khurshid, Azimov, Abdulahat, Jabbarov, Zafarjon“…Likewise, the maximum quantity of micronutrient content viz., Fe, Mn, Zn, Cu, Cr and Si was also recorded in turmeric rhizome treated with NPK + BZnFe (125:100:100:3:6:6 kg/ha). …”
Publicado 2021
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41135por Zemmour, Assia, Dali-Yahia, Radia, Maatallah, Makaoui, Saidi-Ouahrani, Nadjia, Rahmani, Bouabdallah, Benhamouche, Nora, Al-Farsi, Hissa M., Giske, Christian G.“…About ARGs, from 193 ESBL-KP, the majority of strains were multidrug-resistant, the CTX-M-1 enzyme was predominant (99%) and the prevalence of plasmid-mediated quinolone resistance (PMQR) genes was high with aac(6′)-lb-cr (72.5%) and qnr’s (65.8%). From 19 sequenced isolates we identified ESBL, AmpC, and carbapenemase genes: bla(CTX-M-15) (n = 19), bla(OXA-48) (n = 1), bla(CMY-2) (n = 2), and bla(CMY-16) (n = 2), as well as non-ESBL genes: qnrB1 (n = 12), qnrS1 (n = 1) and armA (n = 2). …”
Publicado 2021
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41136por Tao, Yiying, Wei, Xing, Yue, Yue, Wang, Jiaxin, Li, Jianzhong, Shen, Lei, Lu, Guoyuan, He, Yang, Zhao, Shidi, Zhao, Fan, Weng, Zhen, Shen, Xiahong, Zhou, Ling“…Correlation analysis revealed that AEBP1 levels were positively correlated with Cr, 24-h urine protein and serum CYC and negatively correlated with eGFR and LDL, and good diagnostic efficacy for DKD was also found using AEBP1 levels to differentiate DKD patients from T2DM patients or controls. …”
Publicado 2021
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41137por Siegel, Patrick M., Orlean, Lukas, Bojti, István, Kaier, Klaus, Witsch, Thilo, Esser, Jennifer S., Trummer, Georg, Moser, Martin, Peter, Karlheinz, Bode, Christoph, Diehl, Philipp“…Monocyte subset distribution, baseline activation and stimulability were analyzed by flow cytometry using the unique small binding proteins F7 and MAN-1 and the conventional activation markers CD163, CD86, CD69, and CX3CR1. Furthermore, expression of monocyte activation markers in survivors and non-survivors on day 0 was compared. …”
Publicado 2021
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41138“…The titers and sensitivity of the ZEN pAb were determined by indirect noncompetitive ELISA (inELISA) and indirect competitive ELISA (icELISA), respectively, and its specificity was assessed by the cross-reaction test (CR). RESULTS: ZEN-BSA was successfully synthesized, and the molecular binding ratios of ZEN to BSA were 17.2 : 1 (OAE), 14.6 : 1 (CMA), 9.7 : 1 (FA), and 8.3 : 1 (BDE), respectively. …”
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41139por Ma, Minh Tuyet, Badeti, Saiaditya, Chen, Chih-Hsiung, Kim, James, Choudhary, Alok, Honnen, Bill, Reichman, Charles, Calianese, David, Pinter, Abraham, Jiang, Qingkui, Shi, Lanbo, Zhou, Renping, Xu, Huanbin, Li, Qingsheng, Gause, William, Liu, Dongfang“…Furthermore, S309-CAR-NK cells can specifically kill target cells expressing SARS-CoV-2 S protein in vitro and show superior killing activity and cytokine production, compared to that of the recently reported CR3022-CAR-NK cells. Thus, these results pave the way for generating ‘off-the-shelf’ S309-CAR-NK cells for treatment in high-risk individuals as well as provide an alternative strategy for patients unresponsive to current vaccines.…”
Publicado 2021
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41140“…Within subgroups stratified by negative (LN−) or positive (LN+) regional lymph node findings, inverse probability weighting (IPW) adjusted multivariate Fine-Gray compete risk (CR) model and accelerated failure time (AFT) model was used to investigate the factors associated with and cancer-specific survival (CSS) and overall survival (OS). …”
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