“…The primary outcomes will be HRQoL (EORTC QLQ-C30; CR29; and ELD14) and functional capacity (Barthel Index and Short Physical Performance Battery), which will be assessed at diagnosis, at discharge, and one, three, and six months after surgery. …”
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“…Moreover, NPM3 expression was negatively associated with immune B cell and CD4 T cell infiltration, as well as with several immune-related genes (including CCL22, CXCR2, CX3CR1, CCR6, HLA-DOA, HLA-DQA2). KEGG enrichment analysis indicated that NPM3 expression was associated with cell cycle, CAMs, and NSCLC pathway genes. …”
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“….%), and higher concentrations of transition elements such as Co (av. 53.92 ppm), Cr (781 ppm), Ni (av. 1303.6 ppm), V (av. 16.67 ppm), and Zn (av. 55.7 ppm). …”
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“…The ORR was 63.6% (95%CI 44.6–77.8), including 2 cases of CR and 19 cases of PR. The DCR was 19.9%, the median DOR was 19.5 months, and the median TTR was 2.4 months. …”
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“…The aim of this study was to investigate the genomic features of a carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKp) isolate (K-2157) collected in Chile. Antibiotic susceptibility was determined using the disk diffusion and broth microdilution methods. …”
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“…The gene cassette sequence of integron In1337 is IntI1-bla(IMP-4)-qacG2-aacA4′-catB3Δ, while the gene cassette sequence of In2054 is IntI1-aacA4cr-bla(OXA-1)-catB3-arr3-qacEΔ1-sul1. The bla(NDM-1) is located on the transposon TnAS3, and its sequence is IS91-sul-ISAba14-aph (3′)-VI-IS30-bla(NDM-1)-ble-trpF-dsbD-IS91. …”
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“…The combined use of E. fetida and ryegrass showed the best effect of removing chromium from contaminated soils, wih the highest removal rate (63.23%) in acidic soil at low Cr concentrations. After soil ingestion by earthworms, the content of stable chromium (residual and oxidizable forms) in the soil decreased significantly, while the content of active chromium (acid-extractable and reducible forms) increased significantly, thus promoting the enrichment of chromium in plants. …”
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“…RESULTS: Differential gene expression and network analysis of four contrasting oil palm genotypes (IRHO 7001, CTR 3-0-12, CR 10-0-2, and CD 19 − 12) exposed to Al-stress helped to identify a set of genes and modules involved in oil palm early response to the metal. …”
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“…RESULTS: Four patients obtained CR/CRi, even in patients without high expression of CD19 in B-ALL cells, while the other patient received NR after Blinatumomab therapy. …”
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“…The risk of myopia [odds ratio (OR) = 2.12, 95% confidence interval (CI) = 1.52–3.14], high myopia (OR = 1.43, 95% CI = 1.14–1.78) and axial length/corneal radius (AL/CR) ratio of more than 3.0 (OR = 1.82, 95% CI = 1.22–2.72) were significantly higher in the high-risk compared with low-risk class. …”
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“…The main mechanisms of resistance to heavy metals for microorganisms in sediments included oxidation (Mn), reduction (Cr and Hg), efflux (Pb), synergy of reduction and efflux (As), and synergy of oxidation and efflux (Cu). …”
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“…RESULTS: A comprehensive phylogenetic analysis of NR-PKSs established a twelfth clade from which three representatives, enzymes CrPKS1-3 of the webcap mushroom Cortinarius rufoolivaceus, were biochemically characterized. …”
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“…In addition, 10 patients of Group A received anti-HER2 neoadjuvant therapy; only one patient with HR- achieved Grade 5 based on the Miller-Payne system, whereas none of the patients achieved pathological complete response (pCR) based on the Residual Cancer Burden system. …”
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“…Interestingly, the accumulation of guanosine tetraphosphate (ppGpp) was reduced in the presence of mupirocin, which induces a stringent response, in the CRISPR1-Cas-deleted (ΔCR1cas) and both CRISPR-Cas-deleted (ΔCRDcas) mutant strains. …”
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“…Regression analysis revealed that higher concentrations of metals such as Ca, Zn, and Cr significantly decreased labile organic and inorganic P fractions (NaHCO(3)-Pi, R (2 = )0.13, 0.36, 0.09) and their availability (NaHCO(3)-Po, R (2 = )0.01, 0.03, 0.25). …”
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“…NRCC6 fungus is a new efficient and eco-friendly method that revealed a maximum removal of 100% for Pb(2+) and Zn(2+) as well as 97.39, 88.70, 78.95, 74.0, 70.22, 68.57, and 60.0% for Ni(2+), Mn(2+), Cd(2+), Cu(2+), Fe(3+), As(2+), and Cr(6+) from the industrial wastewater, respectively.…”
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“…Based on whole-genome analysis, these 21 CRKP isolates shared a common genetic structure (ISAba125-IS630-bla(NDM−1)-ble(MBL)) and harbored additional resistance determinants (bla(OXA−1), bla(CTX−M−15), bla(SHV−11), bla(SHV−67), aac(6’)-Ib-cr, qnrS1, OqxA, OqxB, catB3, mph(A), sul1, and dfrA12) and mutations in the quinolone resistance-determining regions of gyrA (S83I) and parC (S80I). …”
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“…Resveratrol and EX527, highly specific activator and inhibitor of SIRT1, respectively, were used to explore the function of SIRT1 in vivo and vitro. Cx3Cr1-Cre(ERT2)/Raptor(F/F) mice were used to delete Raptor for inhibiting mammalian target of rapamycin complex 1 (mTORC1) activity in microglia. …”
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“…Of the 36 patients identified, the best overall response (BOR) to ICI was a partial response (PR) in 41.7%, a complete response (CR) in 27.8%, and stable disease in (SD) 13.9%. …”
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