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41361por Jung, Kyu‐Jin, Mandija, Stefano, Cui, Chuanjiang, Kim, Jun‐Hyeong, Al‐masni, Mohammed A., Meerbothe, Thierry G., Park, Mina, van den Berg, Cornelis A. T., Kim, Dong‐Hyun“…For comparison purposes, various conventional phase‐based EPT reconstruction methods were used that ignore [Formula: see text] magnitude information, such as Savitzky–Golay kernel combined with Gaussian filter (S‐G Kernel), phase‐based convection‐reaction EPT (cr‐EPT), magnitude‐weighted polynomial‐fitting phase‐based EPT (Poly‐Fit), and integral‐based phase‐based EPT (Integral‐based). …”
Publicado 2023
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41362por Yin, Cunli, Hu, Bin, Yang, Xi, Kou, Lingna, Tian, Bo, Wang, Chenghao, Li, Siru, Liu, Bin, Ge, Jun“…The primary endpoint of the study was pathologic complete response (pCR). The secondary endpoints were objective response rate (ORR), and safety. …”
Publicado 2023
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41363por Hartman, Katharina, Steiner, Guido, Siegel, Michel, Looney, Cary M., Hickling, Timothy P., Bray-French, Katharine, Springer, Sebastian, Marban-Doran, Céline, Ducret, Axel“…Here, we address this issue by testing various commercially available clones of MHC-II pan (CR3/43, WR18, and Tü39), HLA-DP (B7/21), and HLA-DQ (SPV-L3 and 1a3) antibodies in the MAPPs assay, and characterizing identified peptides according to binding specificity. …”
Publicado 2023
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41364por Villa, Pedro A, Lainez, Nancy, Jonak, Carrie R, Berlin, Sarah, Ethell, Iryna, Coss, Djurdjica“…Villa: None. N. Lainez: None. C.R. Jonak: None. S. Berlin: None. I. Ethell: None. …”
Publicado 2023
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41365“…Disclosure: C.R. Medavarapu: None. M. McNutt: None. Introduction: Maturity-onset diabetes of the young (MODY) is a group of autosomal dominantly inherited disorders of non-autoimmune diabetes mellitus. …”
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41366“…Workup was relevant for TSH 94.7 (0.350-5.0 mcU/ml), WBC 5.2 (4.2-11.0 k/mcl), Hgb 9.2 (12.0-15.5 g/dl), Na 141 (135-145 mmol/L), Cr 1.71 (0.51-0.95 mg/dl), negative Troponins, NT pro BNP 2590 (less then125 pg/ml) D Dimer 1.06. …”
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41367“…Samuel SM, Varghese E, Triggle CR et al. COVID-19 Vaccines and Hyperglycemia-Is There a Need for Postvaccination Surveillance?. …”
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41368por Agramonte Villar, Scarlet P, Gil Vega, Carlos R, Reynoso Ortiz, Jose M, Sosa Pinedo, Lisbeth R, Vasquez Morel, Roberto A, Polanco Santos, Carmen M, San Martin, Vicente T“…Agramonte Villar: None. C.R. Gil Vega: None. J.M. Reynoso Ortiz: None. L.R. …”
Publicado 2023
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41369por Kristeleit, Rebecca, Leary, Alexandra, Delord, Jean Pierre, Moreno, Victor, Oaknin, Ana, Castellano, Daniel, Shappiro, Geoffrey I., Fernández, Cristian, Kahatt, Carmen, Alfaro, Vicente, Siguero, Mariano, Rueda, Daniel, Zeaiter, Ali, Awada, Ahmad, Santaballa, Ana, Zaman, Khalil, Sehouli, Jalid, Subbiah, Vivek“…Secondary endpoints included duration of response (DoR), progression-free survival (PFS), overall survival (OS), safety and an exploratory translational study. Confirmed complete (CR) and partial response (PR) was reported in two and six patients, respectively (ORR = 11.3%; 95%CI, 5.0–21.0%). …”
Publicado 2023
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41370por Sun, He, Chen, Tong, Li, Xin, Zhu, Yonghong, Zhang, Shuang, He, Ping, Peng, Yali, Fan, Qiuling“…Urinary microalbumin, total cholesterol (TC), creatinine (Cr), urea, and systolic blood pressure (SBP) were significantly positively correlated with serum miR-21. …”
Publicado 2023
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41371por Xu, Qianwen, Shi, Yi, Xue, Lei, An, Furun, Xu, Hui, Liu, Xin, Zhu, Xiaoyu, Sun, Zimin, Zhai, Zhimin, Wang, Xingbing“…Fourteen patients (53.8%) achieved complete remission (CR) after CART2. CART2 exhibited an inferior response rate (CART2: 53.8%, 14/26; CART1: 81.0%, 64/79; P = 0.006) and a lower incidence of severe CRS (CART2: 7.7%, 2/26; CART1: 30.4%, 24/79; P = 0.020) compared with CART1, with a median progression-free survival (PFS) and a median overall survival (OS) of 6.2 months and 11.2 months, respectively. …”
Publicado 2023
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41372por Okojie, Akhabue K., Uweru, Joseph O., Coburn, Morgan A., Li, Sihan, Cao-Dao, Vivian D., Eyo, Ukpong B.“…PLX3397 chow treatment at 660 mg/kg for 7 days significantly reduced CD45(+) macrophages, CX3CR1-GFP cells, CD11b(+)CD45(intermediate) cells, and P2RY12 expression in the brain. …”
Publicado 2023
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41373Real-world clinical outcomes of cefiderocol therapy in the Veterans Health Administration, 2019–2022“…Background: Cefiderocol is a novel siderophore cephalosporin with broad-spectrum activity. In the CREDIBLE-CR phase 3 clinical trial examining treatment of carbapenem-resistant gram-negative infections, cefiderocol had similar clinical and microbiological efficacy compared to the best available therapy, but the mortality rate was unexpectedly higher in the cefiderocol group. …”
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41374por Karbian, Netanel, Eshed-Eisenbach, Yael, Zeibak, Marian, Tabib, Adi, Sukhanov, Natasha, Vainshtein, Anya, Morgan, B. Paul, Fellig, Yakov, Peles, Elior, Mevorach, Dror“…Finally, we show that the nodes of Ranvier lack other complement-membrane regulatory proteins, including CD46, CD55, CD35, and CR1-related gene-y (Crry), rendering this area highly exposed to complement attack. …”
Publicado 2023
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41375por Gao, Jia, Tian, Meirong, Liu, Jun, Chen, Jingjing, Zhang, Lei, Wang, Xiaodong, Yan, Ling, Liu, Qiwang, Wen, Jin“…The composite reliability (CR), average variance extracted (AVE) and correlation coefficients of all factors were within the standard range, which showed that the construction validity and discrimination validity of the model were ideal. …”
Publicado 2023
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41376“…The contents of furoamic acid and 5-hydroxymethylfurfural were determined by high-performance liquid chromatography, the color difference was determined by CR-400 color difference meter, and the internal fluorescence spectrum was determined by F-320 fluorescence spectrophotometer. …”
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41377“…RESULTS: The geometric mean urinary zinc concentration (µg/g-Cr) was lower in EQP than in non-EQP (p = 0.0136 by t-test after logarithm transformation). …”
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41378por Yu, Lan, Zhang, Tao, Yang, Jiacheng, Zhang, Rongfei, Zhou, Junbo, Ding, Fan, Shao, Chaogang, Guo, Rongkai“…Heavy metal tolerance assay indicated L. aestuarii GYF-1 possessed minimal inhibition values of 2 mM, 10 mM, 6 mM, 4 mM, 6 mM, 0.8 mM, and 4 mM for CdCl(2), K(2)CrO(4), CuCl(2), NiCl(2), Pb(CH(3)COO)(2), ZnSO(4), and FeCl(2), respectively. …”
Publicado 2023
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41379por Huang, Yi, Liangpunsakul, Suthat, Rudraiah, Swetha, Ma, Jing, Keshipeddy, Santosh K., Wright, Dennis, Costa, Antonio, Burgess, Diane, Zhang, Yuxia, Huda, Nazmul, Wang, Li, Yang, Zhihong“…These included C-X3-C motif chemokine receptor 1 (Cx3cr1) associated with inflammation, cyclin B (Ccnb) associated with cell cycle, DNA topoisomerase 2-alpha (Top2a) associated with intracellular component, and fibrillin (Fbn) and fibromodulin (Fmod) associated with extracellular matrix. …”
Publicado 2023
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41380“…CONCLUSION: The study showed combination therapy had better OR and CR rates, longer survival, and more toxicity than monotherapy. …”
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