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  1. 41421
    “…The therapeutic effect of rSj-Cys on sepsis was evaluated by observing the survival rates of mice for 96 h after CLP and the pathological injury of liver, kidney and lung by measuring the levels of alanine transaminase (ALT), aspartate transaminase (AST), blood urea nitrogen (BUN) and creatinine (Cr) in sera and the tissue sections pathology, and the expression of MyD88 in liver, kidney and lung tissues. …”
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    Therapeutic effect of Schistosoma japonicum cystatin on bacterial sepsis in mice
  2. 41422
    “…We also identified contig bins containing crAssphage-like contigs with higher abundance in healthy patients and a putative Veillonella genus prophage associated with cirrhosis patients. …”
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    VirFinder: a novel k-mer based tool for identifying viral sequences from assembled metagenomic data
  3. 41423
    “…Activation of inflammatory mediators, such as high mobility group box 1 (HMGB1) and pro-inflammatory cytokines, as well as increased expression of Toll-like receptor 2 (TLR2), TLR4 and fractalkine/CX3C chemokine receptor 1 (CX3CR1) cell surface receptors were prominent in 2 DIV microglia, while elevation of matrix metalloproteinase 9 (MMP9) was marked in 16 DIV cells. …”
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    Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation
  4. 41424
    “…Out of the 410 tested lenses, 80% were polycarbonate; 2% were polymethyl methacrylate (PMMA); 5% CR-39 (with polarizing filter inside); 12.8% polyamide; 0.2% glass. …”
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    Building a resistance to ignition testing device for sunglasses and analysing data: a continuing study for sunglasses standards
  5. 41425
    “…In the cefiderocol global surveillance study that focused on carbapenem-resistant Gram-negatives (SIDERO-CR-2014/2016), the most frequent bacterial species recovered from patients with urinary tract infection (UTI) were K. pneumoniae and P. aeruginosa. …”
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    In Vivo Efficacy of Cefiderocol against Carbapenem-Resistant Gram-Negative Bacilli in Murine Urinary Tract Infection Models
  6. 41426
    “…Both 100 and 5kDa achieved a substantial antigen reduction (using CrAg LFA [initial titer]-[final titer]; [1:10(5)]–[1:10(4)] and [1:10(5)]–[1:10(2)], respectively). …”
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    In Vitro Characterization of the Neurapheresis™ System for the Treatment of Cryptococcal Meningitis
  7. 41427
    “…Additionally, oqxAB was co-located with multiple resistance genes on the same plasmid, such as aac(6′)-Ib-cr and/or qnrS, which were identified in two F-:A18:B- plasmids from pigs, and bla(CTX−M−55), rmtB, fosA3, and floR, which were detected in two N1-F33:A-:B- plasmids from patients. …”
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    Characterization of oqxAB in Escherichia coli Isolates from Animals, Retail Meat, and Human Patients in Guangzhou, China
  8. 41428
    “…The analyses indicate that spread of CTX-M-15-producing E. coli in German food samples were associated with a multireplicon IncF (FIA FIB FII) plasmid and additional antimicrobial resistance genes such as aac(6)-Ib-cr, bla(OXA−1), catB3, different tet-variants as well as a class 1 integron with an aadA5/dfrA17 gene cassette. …”
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    CTX-M-15-Producing E. coli Isolates from Food Products in Germany Are Mainly Associated with an IncF-Type Plasmid and Belong to Two Predominant Clonal E. coli Lineages
  9. 41429
    “…In immune-competent adults, the sensitivity of TST and QFT-GIT were estimated to be 84% (95% credible interval [CrI] 82–85%) and 52% (50–53%), respectively. The specificity of QFT-GIT was 97% (96–97%) in non-BCG-vaccinated and 93% (92–94%) in BCG-vaccinated immune-competent adults. …”
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    Interferon-gamma release assay for the diagnosis of latent tuberculosis infection: A latent-class analysis
  10. 41430
    “…The syntheses and properties of four magnetically-supramolecular oligomers of triangular Mn(3) units are reported: dimeric [Mn(6)O(2)(O(2)CMe)(8)(CH(3)OH)(2)(pdpd)(2)] (3) and [Mn(6)O(2)(O(2)CMe)(8)(py)(2)(pdpd)(2)](ClO(4))(2) (4), and tetrameric [Mn(12)O(4)(O(2)CR)(12)(pdpd)(6)](ClO(4))(4) (R = Me (5), (t)Bu (6)). …”
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    Supramolecular aggregates of single-molecule magnets: exchange-biased quantum tunneling of magnetization in a rectangular [Mn(3)](4) tetramer
  11. 41431
    “…Two subjects from Cohort 1 and 2 showed downstaging and finally achieved surgical complete response (CR). CONCLUSIONS: HF10 direct injection under EUS-guidance in combination with erlotinib and gemcitabine was a safe treatment for locally advanced pancreatic cancer. …”
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    A Phase I clinical trial of EUS-guided intratumoral injection of the oncolytic virus, HF10 for unresectable locally advanced pancreatic cancer
  12. 41432
    Publicado 2017
    “…Evaluation of complete response (CR) or partial response (PR) patients defined as sensitive group, progressive disease (PD) patients defined as resistant group. …”
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    应用MALDI-TOF-MS检测肺鳞癌患者血清多肽并分析其与化疗疗效相关性
  13. 41433
    “…The nature of the dose-response relationship in terms of cure rate (CR) was the primary objective. Egg reduction rate (ERR) and tolerability were secondary outcomes. …”
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    Efficacy and safety of ascending doses of praziquantel against Schistosoma haematobium infection in preschool-aged and school-aged children: a single-blind randomised controlled trial
  14. 41434
    Publicado 2014
    “…It was beneficial to survival if the effect of first-line chemotherapy was SD or PR-CR and the proper chemotherapy cycle number was 4-6 cycles. …”
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    单中心394例广泛期小细胞肺癌的一线化疗及生存分析
  15. 41435
    “…Other AMR genes detected were qnrS, qnrB, aac(6’)Ib-cr, dhfr1, aadB, aac(3)-IV, tetA, tetB, tetD, catI, blaCTX, blaSHV, and blaTEM. …”
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    A study of virulence and antimicrobial resistance pattern in diarrhoeagenic Escherichia coli isolated from diarrhoeal stool specimens from children and adults in a tertiary hospital, Puducherry, India
  16. 41436
    “…Out of 110 isolates, 25 isolates (22.7%) were positive to qnrA, 23 (20.9%) to qnrB, 7 (6.4%) to qnrS1, 7 (6.4%) to aac(6′)lb-cr, 5 (4.5%) to qnrD, and 1 (0.9%) to qnrC genes. …”
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    An evaluation of multidrug-resistant Escherichia coli isolates in urinary tract infections from Aguascalientes, Mexico: cross-sectional study
  17. 41437
    “…OprD was defective in 13% of the strains (all with CR phenotype); carbapenem resistance triggering mutations (F170 L, W277X, S403P) were present in 29% of the strains. …”
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    Multidrug resistant Pseudomonas aeruginosa in Estonian hospitals
  18. 41438
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    Clinical Profile of Patients With Chronically Occluded Coronary Arteries: A Single Center Study
  19. 41439
    “…Patients with the HER2+ and TNBC subtypes showed significantly higher pCR rates than patients with luminal types (P < .05). …”
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    Retrospective analysis of concurrent docetaxel and epirubicin neoadjuvant versus adjuvant chemotherapy: Which leads to better outcomes for different subtype breast cancer patients?
  20. 41440
    “…Although crustal elements (Al, Ca, Fe, K, and Mg) dominated the metallic content of marine PM(2.5), trace anthropogenic metals (Cd, As, Ni, and Cr) increased significantly during the northeastern monsoon periods, particularly in winter. …”
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    Chemical characteristics, source apportionment, and regional transport of marine fine particles toward offshore islands near the coastline of northwestern Taiwan Strait
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