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41581por Breen, William G., Hathcock, Matthew A., Young, Jason R., Kowalchuk, Roman O., Bansal, Radhika, Khurana, Arushi, Bennani, N. Nora, Paludo, Jonas, Villasboas Bisneto, Jose C., Wang, Yucai, Ansell, Stephen M., Peterson, Jennifer L., Johnston, Patrick B., Lester, Scott C., Lin, Yi“…We sought to describe metabolic and volumetric PET prognostic factors at one month post-CAR-T and identify which patients with partial response (PR) or stable disease (SD) are most likely to subsequently achieve complete response (CR), and which will develop progressive disease (PD) and death. …”
Publicado 2022
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41582por Zheng, Limei, Yan, Xiaorong, Hu, Chengcong, Zhang, Peng, Chen, Yupeng, Zheng, Qiaoyan, Hu, Liwen, Wang, Mi, Li, Guoping, Wu, Ping, Jiang, Changzhen, Tian, Jing, Zhang, Sheng, Wang, Xingfu“…Stains of chromograninA (CgA), synaptophysin (Syn), Calretinin (CR) were positive. Axotomy-like expression was observed in neurofilament (NF) staining. …”
Publicado 2022
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41583“…CONCLUSIONS: Acute renal function deterioration was predicted by increased urinary L-FABP excretion within 6 h after receiving CIS-CT and, in those with AKI, the increase in urinary L-FABP excretion preceded the rise in sCr by over 2 days. In contrast, no appreciable changes in urinary L-FABP levels were observed in patients with stable renal function throughout the whole observation period. …”
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41584por Hao, Jingchen, Zeng, Zhangrui, Xiao, Xue, Ding, Yinhuan, Deng, Jiamin, Wei, Yueshuai, Liu, Jinbo“…WGS and conjugation revealed that LZ00114 belonged to ST410 and carried a bla(NDM-5)-harboring self-transmissible IncX3 plasmid and a multi-replicon IncFII/FIA/FIB plasmid carrying bla(OXA-1)-bla(CTX-M-55)-tet(B)-aac(6’)-Ib-cr-dfrA17-sul1-fosA3. Comparative genomics revealed genetic relatedness between LZ00114 and strains isolated from other regions. …”
Publicado 2022
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41585por Phetburom, Nattamol, Boueroy, Parichart, Chopjitt, Peechanika, Hatrongjit, Rujirat, Nuanualsuwan, Suphachai, Kerdsin, Anusak“…Seventy-two K. oxytoca isolates (18.75%) were examined for antimicrobial-resistant genes (β-lactamase [bla(TEM), bla(CTX-M), and bla(SHV)]) and fluoroquinolone-resistant genes (qnrA, qnrB, qnrC, qnrD, qnrS, oqxAB, aac(6’)-Ib-cr, and qepA). RESULTS: The most common genotype was bla(CTX-M) (58/72, 80.55%), followed by bla(TEM) with bla(CTX-M) (7/72, 9.72%) and bla(TEM) (6/72, 8.33%). …”
Publicado 2022
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41586por Wang, Chunxue, Zhao, Dongyang, Zheng, Liang, Bao, Xiaowei, Yang, Qian, Jiang, Sen, Zhou, Xiaohui, Tang, Lunxian, Liu, Zhongmin“…ETHICS AND DISSEMINATION: This study has been approved by the Research Ethics Board of East Hospital, Tongji University (Shanghai, China), which has accepted responsibility for supervising all aspects of the study (DFSC-2021(CR-04). The results of this study will be presented at both national and international conferences and be considered for publication in a peer-reviewed scientific journal. …”
Publicado 2022
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41587“…In addition, multivariate analysis identified 6 significant factors associated with PFS: cfDNA reduction of ≥20%, age <65 years, Eastern Cooperative Oncology Group (ECOG) score ≥2, driver gene mutation, chemotherapy combined regimen, and treatment response of complete response (CR) and partial response (PR). The nomogram could predict the 2-year PFS probability of advanced NSCLC patients after treatment, and the C-index was 0.817. …”
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41588por Youn, Chun Song, Park, Kyu Nam, Kim, Soo Hyun, Lee, Byung Kook, Cronberg, Tobias, Oh, Sang Hoon, Jeung, Kyung Woon, Cho, In Soo, Choi, Seung Pill“…When two prognostic factors were combined, any combination of prognostic factors had a false positive rate (FPR) of 0 (95% CI 0–5.6 for combination of no PR/CR and poor CT, 0–30.8 for combination of No SSEP N20 and NSE 60). …”
Publicado 2022
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41589por Lehtomäki, Kaisa, Stedt, Hanna P., Osterlund, Emerik, Muhonen, Timo, Soveri, Leena-Maija, Halonen, Päivi, Salminen, Tapio K., Kononen, Juha, Kallio, Raija, Ålgars, Annika, Heervä, Eetu, Lamminmäki, Annamarja, Uutela, Aki, Nordin, Arno, Lehto, Juho, Saarto, Tiina, Sintonen, Harri, Kellokumpu-Lehtinen, Pirkko-Liisa, Ristamäki, Raija, Glimelius, Bengt, Isoniemi, Helena, Osterlund, Pia“…In the RAXO-study that evaluated repeated resectability, a multi-cross-sectional HRQoL substudy with 15D, EQ-5D-3L, QLQ-C30, and QLQ-CR29 questionnaires was conducted. Mean values of patients in different treatment groups were compared with age- and gender-standardized general Finnish populations. …”
Publicado 2022
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41590por Liberini, Virginia, Pizzuto, Daniele A., Messerli, Michael, Orita, Erika, Grünig, Hannes, Maurer, Alexander, Mader, Cäcilia, Husmann, Lars, Deandreis, Désirée, Kotasidis, Fotis, Trinckauf, Josey, Curioni, Alessandra, Opitz, Isabelle, Winklhofer, Sebastian, Huellner, Martin W.“…SUVmax of metastases, brain background, target-to-background ratio (TBR), and contrast recovery (CR) ratio were recorded for each reconstruction. …”
Publicado 2022
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41591por Li, Cong, Yu, Haifeng, Chen, Xi, Han, Shuiyun, Peng, Shuailing, Lei, Tao, Yang, Haiyan“…At the time of iPET-CT scanning, 250, 45, and 12 patients exhibited complete response (CR), partial response (PR), and stable disease (SD)/progressive disease (PD), respectively. …”
Publicado 2022
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41592por Wynberg, Elke, Han, Alvin X., Boyd, Anders, van Willigen, Hugo D.G., Verveen, Anouk, Lebbink, Romy, van der Straten, Karlijn, Kootstra, Neeltje, van Gils, Marit J., Russell, Colin, Leenstra, Tjalling, de Jong, Menno D., de Bree, Godelieve J., Prins, Maria“…The median half-life of spike- and RBD-binding IgG levels were, in days (95%CrI), 233 (183–324) and 181 (147–230) among participants with PASC, and 170 (125–252) and 144 (113–196) among those without PASC, respectively. …”
Publicado 2022
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41593por Çokgezer, Simay, Elverdi, Tuğrul, Salihoğlu, Ayşe, Ar, Muhlis Cem, Öngören, Şeniz, Başlar, Zafer, Eşkazan, Ahmet Emre“…In patients receiving ABVD, 95% and 92.7% of the cases aged 50–59 and ≥60 years had CR, respectively (p=0.999). Age groups were comparable in terms of hematological and non-hematological toxicities (p=0.369, p=0.127, respectively). …”
Publicado 2022
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41594por Wang, Jianzheng, He, Yunduan, Zhang, Baiwen, Lv, Huifang, Nie, Caiyun, Chen, Beibei, Xu, Weifeng, Zhao, Jing, Cheng, Xiaojiao, Li, Qingli, Tu, Shuiping, Chen, Xiaobing“…RESULTS: Thirty-nine patients were enrolled and eligible for response assessment. Complete response (CR) was not observed, 15 patients achieved partial response (PR), 16 patients had stable disease (SD) and 9 patients had progressive disease (PD). …”
Publicado 2022
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41595“…SPP1, TREM1, GPM6A, CCL19, CR1, NCAM1, CNTN1, TLR8, SDC1, and COL6A6 were the 10 hub genes identified to be associated with CAVD. …”
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41596por Honda, Yuki, Wakabayashi, Kohei, Sato, Chisato, Ikeda, Naoko, Sato, Ken, Suzuki, Toshiaki, Shibata, Keita, Shinke, Toshiro“…The incidence of MACCE (log-rank: P = 0.009) was higher in patients with severe CKD > stage 3a in the SMI subgroup. Urinary albumin (mg/gCr) was associated with MACCE in the SMI subgroup [HR 3.37, 95%CI (1.170–9.521), P = 0.025] after adjusting for age, sex, and conventional risk factors. …”
Publicado 2022
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41597por Pennella, Carla L., Cassina, Tamara Muñoz, Rossi, Jorge G., Baialardo, Edgardo M., Rubio, Patricia, Deu, María A., Peruzzo, Luisina, Guitter, Myriam R., Sanchez de La Rosa, Cristian G., Alfaro, Elizabeth M., Felice, María S.“…Analysis of administered treatment was done on 32/33 ML-DS patients who achieved CR according to receiving or not high-dose ARA-C block (HDARA-C), and no difference in 5-year EFSp was observed (p = 0.172). …”
Publicado 2022
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41598por Ma, Vincent T., Chamila Perera, Alahendra A., Sun, Yilun, Sitto, Merna, Waninger, Jessica J., Warrier, Govind, Green, Michael D., Fecher, Leslie A., Lao, Christopher D.“…Clinical benefit response (CBR) was assessed, defined as SD (stable disease) + PR (partial response) + CR (complete response) by imaging. Among patients who achieved a CBR after 1 or 2 doses of I/N, a multivariable Cox regression of survival was used to compare 1 or 2 vs 3 or 4 doses of I/N adjusted by known prognostic variables in advanced melanoma. …”
Publicado 2022
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41599por do Canto, Luisa Matos, da Silva, Jenilson Mota, Castelo-Branco, Patrícia Valèria, da Silva, Ingrid Monteiro, Nogueira, Leudivan, Fonseca-Alves, Carlos Eduardo, Khayat, André, Birbrair, Alexander, Pereira, Silma Regina“…We also found mutations in ten novel genes (KMT2C, SMARCA4, PTPRB, AJUBA, CR1, KMT2D, NBEA, FAM135B, GTF2I, and CIC), thus increasing our understanding of the potential HPV-disrupted pathways. …”
Publicado 2022
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41600por Lima, Ricardo Franco, González Férnandez, Francisco Tomás, Silva, Ana Filipa, Laporta, Lorenzo, de Oliveira Castro, Henrique, Matos, Sérgio, Badicu, Georgian, Pereira, Gonçalo Arezes, De Conti Teixeira Costa, Gustavo, Clemente, Filipe Manuel“…The data comes from 14 players (two setters, five middle blockers, five outside hitters, and two opposites) of an elite team from the Portuguese 1st League (age: 21.7 ± 4.19 years of age; experience: 6.2 ± 3.8 years; body mass: 85.7 ± 8.69 kg; height: 192.4 ± 6.25 cm; BMI: 23.1 ± 1.40 kg/m(2)). The CR10 Borg scale was applied daily to measure the training intensity. …”
Publicado 2022
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