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  1. 41621
    “…We also demonstrated that posttreatment ctDNA was a sensitive indicator for detecting minimal residual disease (MRD) in patients with a high risk of recurrence (HR 6.471; p = 0.014), who were otherwise claimed to achieve radiographic CR (complete remission). CONCLUSIONS: CtDNA is a promising noninvasive tool for prognosis prediction, response assessment, and early relapse prediction of first-line treatment in DLBCL patients. …”
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    Clinical implications of circulating tumor DNA in predicting the outcome of diffuse large B cell lymphoma patients receiving first-line therapy
  2. 41622
    “…Lab evaluation showed elevated alkaline phosphatase 971, normal AST/ALT, vitamin-D 52, normal serum calcium and PTH, elevated random urine fluoride 23 mg/L (<3.2), elevated osteocalcin 292ng/ml (<32), and elevated N-telopeptide 2283 BCE/mmol cr (<64). Upper extremity x-rays showed evidence of diffuse mature periosteal reaction involving the proximal humerus, radius, ulna, and metacarpals and prominent medial and lateral epicondylar enthesopathy consistent with fluorosis. …”
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    PSAT193 Skeletal Fluorosis due to Inhalant Abuse
  3. 41623
    “…. | There were no differences on admission clinical characteristics between the non-frail/pre-frail older adults and the frail older adults except for Creatinine (BMI: 32.4 ± 9 vs. 36.83± 13, p=0.21; HbA1c%: 9.3 ± 2 vs. 8.72± 2, p=0.18; Admission BG: 227 ± 114 vs. 194. 07± 75 mg/dl, p=0.26; Cr: 1.16 ± 1 vs. 1.65± 1. 0). There were no differences in GV by coefficient of variation (CV), amplitude of glucose excursion (MAGE), and standard deviation (SD) between the two groups. …”
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    LBSUN215 Evaluation Of Glycemic Control By Continuous Glucose Monitoring Among Hospitalized Older Adults With Type-2 Diabetes And Frailty
  4. 41624
    “…In addition, irradiation-accelerated transport of Mn and Cr to the cladding surface to form a protective oxide layer as a self-repairing mechanism was discovered and is believed capable of mitigating long-term corrosion. …”
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    A novel approach on designing ultrahigh burnup metallic TWR fuels: Upsetting the current technological limits
  5. 41625
    “…The deracoxib remission rate (42% CR+PR) compared very favorably to that with single-agent cyclooxygenase inhibitors in more advanced canine InvUC (17-25%), supporting the value of early intervention. …”
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    Identification of a naturally-occurring canine model for early detection and intervention research in high grade urothelial carcinoma
  6. 41626
    “…The Consistency Ratio (CR) was well below the 0.1 cut point. The LCRI(IL) was moderate though significantly correlated with age-adjusted lung cancer incidence (r = 0.449, P < 0.05) and mortality rates (r = 0.495, P < 0.05). …”
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    Construction and case study of a novel lung cancer risk index
  7. 41627
    “…The rapid emergence of extended-spectrum beta-lactamase (ESBL), AmpC, and carbapenemase (CR) producers has made the treatment of such infections increasingly more challenging. …”
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    Trends of antimicrobial resistance in patients with complicated urinary tract infection: Suggested empirical therapy and lessons learned from a retrospective observational study in Oman
  8. 41628
    “…Multivariate analysis indicated that male sex (P < 0.001), older age (P < 0.001), high body mass index (BMI, P < 0.05), high fasting plasma glucose (FPG, P < 0.001), hypertension (P = 0.015), dyslipidaemia (P < 0.001), and low serum creatinine (sCr, P < 0.05) at presentation were risk factors for T2DM. …”
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    Establishment of dynamic nomogram and risk score models for T2DM: a retrospective cohort study in Beijing
  9. 41629
    “…The most common mechanisms of resistance to 3(rd) generation cephalosporins, quinolones and to aminoglycosides were CTX-M-15 (74.4%), qnrB (63.6%), aac(6')-Ib-cr (87.5%), respectively. Many other AMR genetic determinants were identified (Fig. 1). …”
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    151. Molecular diversity and resistance mechanisms of Klebsiella pneumoniae bloodstream infections in Peru
  10. 41630
    “…The proportion achieving HIV RNA < 50 copies/mL at week 24 was 4/12 (33%) in the curART arm vs 7/13 (54%) in the ABC/3TC/DTG arm; median Bayesian risk difference, 5% (95% CrI, −17 to 28%) higher for those randomized to ABC/3TC/DTG. …”
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    Virological Outcomes After Switching to Abacavir/Lamivudine/Dolutegravir Combined with Adherence Support in People Living with HIV with Poor Adherence: A Phase IV, Multicentre Randomized Prospective Open Label Study (TriiADD-CTN 286)
  11. 41631
    “…Moreover, ABA triggered the expression of P5CS and P5CR, but inhibited the ProDH expression, which might contribute to Pro accumulation. …”
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    Role of exogenous abscisic acid in freezing tolerance of mangrove Kandelia obovata under natural frost condition at near 32(°)N
  12. 41632
    “…According to the whole-genome sequencing analysis, many common resistance genes were identified, including bla(KPC-112), bla(OXA-1), bla(CTX-M-15), bla(TEM-1B), bla(SHV-28), aac(6′)Ib-cr, aac(3)-IId, qnrS1, catA2, catB4, and fosA6, and mutations of GyrA (GyrA-83F and GyrA-87A) and ParC (ParC-80I) were also found. …”
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    Identification of KPC-112 from an ST15 Klebsiella pneumoniae Strain Conferring Resistance to Ceftazidime-Avibactam
  13. 41633
    “…We found that MS negativity was significantly associated with improved progression-free survival (PFS) even in patients with complete response (CR) at all investigated follow-up time points. The prognostic impact was independent of established risk factors, such as the revised International Staging System. …”
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    Implications and prognostic impact of mass spectrometry in patients with newly-diagnosed multiple myeloma
  14. 41634
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    Anthracycline-Induced Cardiotoxicity in Breast Cancer Patients: A Five-Year Retrospective Study in 10 Centers
  15. 41635
    “…In total, 119 (75%) patients reached M1 evaluation; 64 (53%, 64/119) had a complete response (CR); 91% were Deauville Score (DS) 1-3. Progression-free survival (PFS) and overall survival (OS) were significantly worse in patients with DS-5 at M1, than in patients with DS 1-3 (PFS hazard ratio [HR]=6.37, 95% confidence interval [CI]: 3.5-11.5 vs. …”
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    Positron emission tomography-imaging assessment for guiding strategy in patients with relapsed/refractory large B-cell lymphoma receiving CAR T cells
  16. 41636
    “…The rates of complete remission (CR) and partial remission (PR) at 6 months and 12 months, respectively, were 65% and 20% and 78% and 8%. …”
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    Long-Term Outcomes of Children and Adolescents With Biopsy-Proven Childhood-Onset Lupus Nephritis
  17. 41637
    “…We show that sequential improvement of five components — NLS, crRNA, LbCas12a, adenine deaminase, and linker — leads to a remarkable increase in activity from almost undetectable levels to 40% on an extrachromosomal GFP reporter. …”
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    Systematic optimization of Cas12a base editors in wheat and maize using the ITER platform
  18. 41638
    “…For efficacy analysis, Overall response rate (ORR), complete response rate (CR), partial response rate (PR), rate of stable disease (SDR), rate of progressive disease (PDR), median progression-free survival (mPFS), 12-/24-month PFS, and 12-month overall survival (OS) were assessed. …”
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    Safety and efficacy of dual PI3K-δ, γ inhibitor, duvelisib in patients with relapsed or refractory lymphoid neoplasms: A systematic review and meta-analysis of prospective clinical trials
  19. 41639
    “…PATIENTS AND METHODS: Based on our customized grading standard, the VISIA CR photos of 111 young women aged from 18 to 25 in Shanghai were collected and scored by the severity of pores, acne, spots, and wrinkles. …”
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    The Characteristics of the Skin Physiological Parameters and Facial Microbiome of “Ideal Skin” in Shanghai Women
  20. 41640
    “…The cognate antigens are polymorphic structures expressed on several glycoproteins on the neutrophils, i.e., antigens HNA-1a, −1b, −1c, and −1d on Fc-γ-receptor IIIb; HNA-2 on CD177; HNA-3a and −3b on choline transporter-like protein 2; HNA-4a and −4b on CD11b/αM subunit of the αMβ2-integrin (CD11b/CD18, Mac-1, CR3); and HNA-5a and −5b on αL-subunit (CD11a) of the αLβ2 integrin (CD11a/CD18), leukocyte function associated molecule (LFA)-1. …”
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    Phenotyping and Genotyping of HNA: Prevalence, Risk of Alloimmunization, and HNA Incompatibilities in Indians
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