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28881“…Apparent regulation of ECS and TRPV1 in response to pharmacological intervention is a strong justification for novel ECS-based multi-target drug treatment in OA.…”
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28882por Shosha, Esraa, Xu, Zhimin, Narayanan, S. Priya, Lemtalsi, Tahira, Fouda, Abdelrahman Y., Rojas, Modesto, Xing, Ji, Fulton, David, Caldwell, R. William, Caldwell, Ruth B.“…A1 overexpression or high glucose treatment increased SA β-Gal activity in cultured ECs. These results demonstrate that A1 is critically involved in diabetes-induced senescence of retinal ECs. …”
Publicado 2018
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28883“…INTERVENTION(S): Expanded carrier screening (ECS) with the use of a commercially available targeted genotyping panel including >700 mutations in 180 genes. …”
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28884por Shamloul, Ahmed, Steinemann, Gustav, Roos, Kerrin, Liem, Celine Huajia, Bernd, Jonathan, Braun, Thorsten, Zakrzewicz, Andreas, Berkholz, Janine“…Recently, significant Smyd1 levels were discovered in endothelial cells (ECs) that responded to inflammatory cytokines. Based on these biochemical properties, we hypothesized that Smyd1 is involved in inflammation-triggered signaling in ECs and therefore, investigated its role within the LPS-induced signaling cascade. …”
Publicado 2021
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28885por Kiger, Laurent, Keith, Julia, Freiwan, Abdullah, Fernandez, Alfonso G., Tillman, Heather, Isakson, Brant E., Weiss, Mitchell J., Lechauve, Christophe“…Small artery endothelial cells (ECs) express free α-globin, which causes vasoconstriction by degrading NO. …”
Publicado 2022
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28886“…We present examples from the LHCb Experiment Control System (ECS), which is based on a commercial SCADA software. …”
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28887por Pi, Jingjiang, Cheng, Yu, Sun, Huimin, Chen, Xiaoli, Zhuang, Tao, Liu, Jie, Li, Yixi, Chang, Huan, Zhang, Lin, Zhang, YuZhen, Tao, Ting“…RESULTS: Apln-CreERT:mT/mG mice exhibited eGFP signal only in the sprouting angiogenesis, with less eGFP expression in the retinal “optic nerve” area than in that of Cdh5-CreERT: mT/mG mice, which might be due to relative mature vessels in the “optic nerve” area. The ECs sorted by FACS confirmed that the Apelin expression level was higher in eGFP ECs than tdTomato ECs of “optic nerve” area. …”
Publicado 2017
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28888por Canal-Sotelo, Jaume, Trujillano-Cabello, Javier, Larkin, Philip, Arraràs-Torrelles, Núria, González-Rubió, Ramona, Rocaspana-Garcia, Mariona, Barallat-Gimeno, Eva“…The Edmonton Classification System for Cancer Pain (ECS-CP) is a classification tool that evaluates different dimensions of pain. …”
Publicado 2018
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28889por Saleh-Ghadimi, Sevda, Alizadeh, Mohammad, Jafari-Vayghan, Hamed, Darabi, Masoud, Golmohammadi, Ali, Kheirouri, Sorayya“…BACKGROUND: The endocannabinoid system (ECS) overactivation, associated with increased inflammatory process, may act as a risk factor for coronary artery disease (CAD). …”
Publicado 2020
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28890“…METHODS: We selected Shenzhen, China, to collect geospatial resources of epidemic communities (ECs) and FCs to determine the ECs’ cumulative opportunities of visiting FCs, as well as evaluate the rationality of medical resources in current ECs. …”
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28891por Liu, Jiwen, Huang, Fuyan, Liu, Jiao, Liu, Xiaoyue, Lin, Ruiyun, Zhong, Xiaosong, Austin, Brian, Zhang, Xiao-Hua“…Horizontally, Nitrosopumilus-like and Nitrosopelagicus-like phylotypes dominated the surface water (3 m) of the Yellow Sea (YS) and East China Sea (ECS), respectively, along with increased abundance of total free-living Thaumarchaeota in ECS. …”
Publicado 2023
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28892por Gao, Lu, Chen, Weixian, Li, Lijun, Li, Juanjuan, Kongling, Wenyao, Zhang, Yaoyang, Yang, Xueping, Zhao, Yanrong, Bai, Jie, Wang, Fu“…Mechanistically, TPPU promoted cell proliferation and angiogenesis, reclined cell apoptosis, and significantly increased CD31(hi)EMCN(hi) endothelial cells (ECs) and SLIT3 and HIF‐1α expression levels in co‐cultured HUVECs and hDPSCs. …”
Publicado 2023
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28893por Marrero, Ana Dácil, Castilla, Laura, Bernal, Manuel, Manrique, Inmaculada, Posligua-García, Joel D., Moya-Utrera, Federico, Porras-Alcalá, Cristina, Espartero, José Luis, Sarabia, Francisco, Quesada, Ana R., Medina, Miguel Ángel, Martínez-Poveda, Beatriz“…In this work, we define a mechanism of action underlying the anti-inflammatory effect of HT-C6, which involves the abrogation of nuclear factor kappa B (NF-κB) pathway activation in ECs. These results, together with the ability of HT-C6 to reduce ROS formation in ECs, point to this compound as a promising HT-derivative to be tested in the treatment of atherosclerosis.…”
Publicado 2023
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28894por Shimizu, Shota, Iba, Tomohiro, Naito, Hisamichi, Rahmawati, Fitriana Nur, Konishi, Hirotaka, Jia, Weizhen, Muramatsu, Fumitaka, Takakura, Nobuyuki“…Here, we report that the number of liver endothelial cells (ECs) including VESCs was lower in aged (27–28 month-old) than young (2–3 month-old) mice. …”
Publicado 2023
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28895“…OBJECTIVES: The interrelationship between circulating MGP levels and renal and cardiac dysfunction, besides echocardiographic calcification score (ECS) was investigated in a sample of type 2 diabetes (T2D) patients. …”
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28896por Noort, Ae R, van Zoest, Katinka PM, Weijers, Ester M, Koolwijk, Pieter, Maracle, Chrissta X, Novack, Deborah V, Siemerink, Martin J, Schlingemann, Reinier O, Tak, Paul P, Tas, Sander W“…NIK is highly expressed in endothelial cells (ECs) in tumour tissues and inflamed rheumatoid arthritis synovial tissue. …”
Publicado 2014
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28897por Zennadi, Rahima“…I tested four different inhibitors of MEK1/2 (MEK), the kinase that activates ERK1/2, in a model of human SSRBC adhesion to TNFα-activated endothelial cells (ECs). SSRBC MEK inhibition abrogated adhesion to non-activated and TNFα-activated ECs to levels below baseline SSRBC adhesion to non-activated ECs in vitro. …”
Publicado 2014
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28898por Liao, Chun-Ta, Fan, Kang-Hsing, Kang, Chung-Jan, Lin, Chien-Yu, Chang, Joseph Tung-Chieh, Tsang, Ngan-Ming, Huang, Bing-Shen, Chao, Yin-Kai, Lee, Li-Yu, Hsueh, Chuen, Wang, Hung-Ming, Liau, Chi-Ting, Hsu, Cheng-Lung, Hsieh, Chia-Hsun, Ng, Shu-Hang, Lin, Chih-Hung, Tsao, Chung-Kan, Fang, Tuan-Jen, Huang, Shiang-Fu, Chang, Kai-Ping, Yen, Tzu-Chen“…CONCLUSION: OSCC patients with neck nodal ECS and esophageal cancer or hepatocellular carcinoma as SSPT have a dismal short-term prognosis.…”
Publicado 2015
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28899por Chen, Gin-Fu, Sudhahar, Varadarajan, Youn, Seock-Won, Das, Archita, Cho, Jaehyung, Kamiya, Tetsuro, Urao, Norifumi, McKinney, Ronald D., Surenkhuu, Bayasgalan, Hamakubo, Takao, Iwanari, Hiroko, Li, Senlin, Christman, John W., Shantikumar, Saran, Angelini, Gianni D., Emanueli, Costanza, Ushio-Fukai, Masuko, Fukai, Tohru“…Mechanistically, Atox1-depleted ECs demonstrate that Cu chaperone function of Atox1 mediated through Cu transporter ATP7A is required for VEGF-induced angiogenesis via activation of Cu enzyme lysyl oxidase. …”
Publicado 2015
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28900“…Previous research has shown that the loss of endothelial cells (ECs) is a common event in many cardiovascular diseases. p120 catenin (p120ctn) plays an important role in the regulation of inflammatory responses in ECs. …”
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