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  1. 29281
    “…Emerging evidence suggests that glioma stem-like cells (GSCs) transdifferentiating into vascular endothelial cells (ECs) possibly contributes to tumor resistance to antiangiogenic therapy. …”
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    A new mosaic pattern in glioma vascularization: exogenous endothelial progenitor cells integrating into the vessels containing tumor-derived endothelial cells
  2. 29282
    “…Levels of 2-AG were shown to be upregulated in a time- and region-specific manner following MPTP administration, indicating that the ECS represents a natural defence mechanism against inflammation, potentiation of which could provide therapeutic benefits. …”
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    Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
  3. 29283
    “…In multivariate logistic regression analysis, Gleason score (GS), PSA and extra-capsular tumour spread (ECS) variables were found to be statistically significant as BCR predictive factors. …”
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    Predictive factors for biochemical recurrence in radical prostatectomy patients
  4. 29284
    “…Concomitantly targeting the TGF-β type I receptor (TβRI) kinase with SB505124 and JAK1-2 with ruxolitinib suppresses JAK1 phosphorylation and blocks proliferative cross-talk between human pancreatic cancer cells (PCCs) and human endothelial cells (ECs), and these anti-proliferative effects were mimicked by JAK1 silencing in ECs. …”
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    Angiogenic gene signature in human pancreatic cancer correlates with TGF-beta and inflammatory transcriptomes
  5. 29285
    “…Administration of an NOX1-specific inhibitor suppressed radiation-induced collagen deposition and fibroblastic changes in the endothelial cells (ECs) of these mice. The results suggested that radiation-induced pulmonary fibrosis may be efficiently reduced by specific inhibition of NOX1, an effect mediated by reduction of fibrotic changes of ECs.…”
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    Effects of NOX1 on fibroblastic changes of endothelial cells in radiation-induced pulmonary fibrosis
  6. 29286
    “…Although endothelial cells (ECs) rely on multiple growth factors and cytokines to grow, antiangiogenic therapies have mainly centered on targeting vascular endothelial growth factor (VEGF). …”
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    PI3K at the crossroads of tumor angiogenesis signaling pathways
  7. 29287
    “…Therefore, the activation of Sirt1 in vascular tissue, which includes ECs, monocytes/macrophages and VSMCs, may be a new therapeutic strategy against atherosclerosis and the increasing resistance to the metabolic disorder-related causal factors of CVD. …”
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    The protective role of Sirt1 in vascular tissue: its relationship to vascular aging and atherosclerosis
  8. 29288
    “…Conditioning by extra carbon sources (ECS), normally added in a solid form, has been reported to be an efficient approach. …”
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    Characterization of biocarbon-source recovery and microbial community shifts from waste activated sludge by conditioning with cornstover: Assessment of cellulosic compositions
  9. 29289
    “…These data indicate that the interactions of the gut microbiota with fatty acid metabolism directly affect host health by modulating n-3 PUFA score and the ECS.…”
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    Bifidobacterium breve with α-linolenic acid alters the composition, distribution and transcription factor activity associated with metabolism and absorption of fat
  10. 29290
    “…Having noticed different standards across ethics committees (ECs), we propose that when multiple ethics reviews of clinical and vaccine trials are carried out during a public health emergency they should be accompanied by transparent communication between the ECs involved. …”
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    Research Ethics Governance in Times of Ebola
  11. 29291
    “…The results demonstrated that 5 µM sildenafil suppressed the proliferation of HemECs and significantly enhanced the rate of apoptosis after 24 h. …”
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    Sildenafil suppresses the proliferation and enhances the apoptosis of hemangioma endothelial cells
  12. 29292
    “…The cell migration depth had a positive correlation with LPS concentration, and thereby the TNF-α concentration. The ECs migrated easier to a deeper zone of the scaffolds prepared at − 10ºC (187 μm in pore diameter) than that at − 20ºC (108 μm in pore diameter) as well. …”
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    Induced migration of endothelial cells into 3D scaffolds by chemoattractants secreted by pro-inflammatory macrophages in situ
  13. 29293
    “…Multivariate analyses revealed that T stage, ECS and LNR are independent prognostic factors of 5-year DFS and disease-specific survival(DSS). …”
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    Lymph node ratio is associated with adverse clinicopathological features and is a crucial nodal parameter for oral and oropharyngeal cancer
  14. 29294
    “…We investigated whether vimentin regulates endothelial cells (ECs) and vascular smooth muscle cells (SMCs) and thereby influences vasomotor tone and arterial stiffness. …”
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    Vimentin knockout results in increased expression of sub-endothelial basement membrane components and carotid stiffness in mice
  15. 29295
    “…Sulforaphane suppresses ECS cell tumor formation and this is associated with reduced levels of YAP1 and ∆Np63α. …”
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    Sulforaphane reduces YAP/∆Np63α signaling to reduce cancer stem cell survival and tumor formation
  16. 29296
    “…Higher activities were observed at the East China Sea (ECS) Kuroshio and the nSCS shelf. The nSCS basin showed a low N(2) fixation activity. …”
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    Nitrogen Fixation by Trichodesmium and unicellular diazotrophs in the northern South China Sea and the Kuroshio in summer
  17. 29297
    “…Since Rudhira is also expressed in endothelial cells (ECs), we further generated Tie2Cre-mediated endothelial knockout (CKO) of rudhira. …”
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    Rudhira/BCAS3 is essential for mouse development and cardiovascular patterning
  18. 29298
    “…This was confirmed by the increase of Ecs from 54.5 ± 3.1% for the control, to an average of 84.7 ± 1.86% on the Dll4 patterned surfaces. …”
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    Spatial patterning of the Notch ligand Dll4 controls endothelial sprouting in vitro
  19. 29299
    “…In this scenario, a link between the endocannabinoid system (ECS) and redox homeostasis impairment appears to be crucial. …”
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    Modulation of the Oxidative Stress and Lipid Peroxidation by Endocannabinoids and Their Lipid Analogues
  20. 29300
    “…The physiopathology of the disease is still incompletely elucidated although the role of fibroblasts, endothelial cells (ECs), immune cells. and the environment (i.e., oxidative stress) has been demonstrated. …”
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    Mesenchymal Stem Cells in Systemic Sclerosis: Allogenic or Autologous Approaches for Therapeutic Use?
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