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29901por Kim, Won Kyu, Kwon, Yujin, Park, Minhee, Yun, Seongju, Kwon, Ja-Young, Kim, Hoguen“…In this study, we performed time-dependent DNA microarray analysis of endothelial cells (ECs) after HMGB-1 or VEGF treatment. The pathway analysis of each gene set upregulated by HMGB-1 or VEGF showed that most HMGB-1-induced angiogenic pathways were also activated by VEGF, although the activation time and gene sets belonging to the pathways differed. …”
Publicado 2017
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29902por Petropoulos, Christos, Guichet, Pierre-Olivier, Masliantsev, Konstantin, Wager, Michel, Karayan-Tapon, Lucie“…Moreover, our study demonstrates that GSCs are highly adaptable cells that are able not only to restore damaged endothelial-derived tubes but also to generate in cooperation with normal endothelial cells (ECs) intact vascular channels. Taken together, our data provide new insights in GBM microvasculature and suggest that GSCs targeting in combination with anti-VEGF therapy may block tumor progression.…”
Publicado 2018
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29903“…To induce angiogenesis, angiogenic growth factors (AGFs) must interact with pro-angiogenic receptors to induce proliferation, protease production and migration of endothelial cells (ECs). The action of AGFs is counteracted by antiangiogenic modulators whose main mechanism of action is to bind (thus sequestering or masking) AGFs or their receptors. …”
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29904“…OSS activated NOX2 and had no significant influence to NOX1 or NOX4 in endothelial cells (ECs). OSS phosphorylated caveolin-1, promoted its binding with endothelial nitric oxide synthase (eNOS), and resulted in deactivation of eNOS. …”
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29905por Flieger, Miroslav, Stodůlková, Eva, Wyka, Stephen A., Černý, Jan, Grobárová, Valéria, Píchová, Kamila, Novák, Petr, Man, Petr, Kuzma, Marek, Cvak, Ladislav, Broders, Kirk D., Kolařík, Miroslav“…While secalonic acids A–C (SAs), the main ergot ergochromes (ECs), are well known toxins, our study is the first to address the question about their contribution to overall ergot toxicity. …”
Publicado 2019
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29906por Xu, Peifang, Feng, Xue, Zheng, Honghao, Feng, Zhongwei, Fu, Zhisheng, Gao, Changyou, Ye, Juan“…The in vitro results showed that the B-PE and processed B-PE films or scaffolds did not exhibit noticeable cytotoxicity to the NIH3T3 fibroblasts and human vascular endothelial cells (ECs). The B-PE scaffolds with a pore size of 280–480 µm were prepared by using a gelatin porogen-leaching method. …”
Publicado 2020
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29907“…PAH is characterized by constant remodeling of the pulmonary artery by increased proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs), fibroblasts (FBs) and endothelial cells (ECs). This remodeling eventually leads to increased pressure in the right ventricle (RV) and subsequent right ventricle hypertrophy (RVH) which, when left untreated, progresses into right ventricle failure (RVF). …”
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29908“…Mechanisms underlying docetaxel resistance are not well elaborated. Endothelial cells (ECs) have been implicated in the progression and metastasis of prostate cancer. …”
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29909por Colón-Cruz, Luis, Rodriguez-Morales, Roberto, Santana-Cruz, Alexis, Cantres-Velez, Juan, Torrado-Tapias, Aranza, Lin, Sheng-Jia, Yudowski, Guillermo, Kensler, Robert, Marie, Bruno, Burgess, Shawn M., Renaud, Olivier, Varshney, Gaurav K., Behra, Martine“…Furthermore, vesicular trafficking in HCs was strongly perturbed suggesting a retrograde action of the endocannabinoid system (ECs) via cnr2 that was modulating HC mechanotransduction. …”
Publicado 2021
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29910por Kong, Lingmiao, Xiao, Fei, Wang, Lijun, Li, Min, Wang, Denian, Feng, Zhongxue, Huang, Luping, Wei, Yong'gang, Li, Hongyu, Liu, Fei, Kang, Yan, Liao, Xuelian, Zhang, Wei“…Herein, we report that intermedin (IMD), a calcitonin family member, promotes vessel fusion by inducing endothelial cells (ECs) to enter a “ready‐to‐anchor” state. IMD promotes vascular endothelial cadherin (VEC) accumulation at the potential fusion site to facilitate anchoring of approaching vessels to each other. …”
Publicado 2020
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29911“…The tubular composite scaffold has well-controlled biophysical and biochemical signals, providing a good matrix for the adhesion and proliferation of vascular endothelial cells (ECs), but resisting to platelets adhesion when exposed to blood. …”
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29912por Komici, Klara, Perna, Angelica, Rocca, Aldo, Bencivenga, Leonardo, Rengo, Giuseppe, Guerra, Germano“…Endothelial Progenitor Cells (EPCs) represent a heterogenous cell population, characterized by the ability to differentiate into mature endothelial cells (ECs), which contribute to vascular homeostasis, neovascularization and endothelial repair. …”
Publicado 2021
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29913“…It will be important to determine if the microorganisms present at given treatment facility are able to remove ECs present in the wastewater.…”
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29914“…It was concluded that the proposed scheme can be used as the theoretical basis to choose the best remanufacturing scheme to ensure the efficient operation of each part in an ECS.…”
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29915“…We found decreased wound healing rate in progerin-expressing ECs under higher shear stress compared with those under low shear. …”
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29916“…Pericytes, glia cells and neurons signal to endothelial cells (ECs) to form and maintain the barriers and control blood flow, helping to create the neurovascular unit. …”
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29917por de Graaf, Mees N. S., Vivas, Aisen, Kasi, Dhanesh G., van den Hil, Francijna E., van den Berg, Albert, van der Meer, Andries D., Mummery, Christine L., Orlova, Valeria V.“…Using this FCB, we found that variation of CS or WSS induce morphological changes to human induced pluripotent stem cell (hiPSC)-derived endothelial cells (ECs) and conclude that control of these parameters using a FCB is necessary to study 3D-VOCs.…”
Publicado 2022
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29918por Lou, Xi, Tang, Yawen, Ye, Lei, Pretorius, Danielle, Fast, Vladimir G, Kahn-Krell, Asher M, Zhang, Jue, Zhang, Jianhua, Qiao, Aijun, Qin, Gangjian, Kamp, Timothy, Thomson, James A, Zhang, Jianyi“…AIMS: We have shown that human cardiac muscle patches (hCMPs) containing three different types of cardiac cells—cardiomyocytes (CMs), smooth muscle cells (SMCs), and endothelial cells (ECs), all of which were differentiated from human pluripotent stem cells (hPSCs)—significantly improved cardiac function, infarct size, and hypertrophy in a pig model of myocardial infarction (MI). …”
Publicado 2023
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29919“…Finally, NP-6A4 decreased phosphorylation of Jun-N-terminal kinase, implicated in apoptosis of ECs in atherosclerotic sites. Taken together, NP-6A4, through its ability to increase AT2R expression and signaling, exerts different cell-specific protective effects in human VSMCs and ECs.…”
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29920“…It is known that Δ-9-tetrahydrocannabinol (THC), the psychoactive component of cannabis, can interact with the endocannabinoid system (ECS) via cannabinoid receptor 1. Components of the ECS are highly involved in regulating mammalian reproductive processes such as oocyte, sperm, and embryo development by modulating gene expression, apoptosis, and several intracellular pathways. …”
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