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29981por Ramella, Martina, Bertozzi, Giulia, Fusaro, Luca, Talmon, Maria, Manfredi, Marcello, Catoria, Marta Calvo, Casella, Francesco, Porta, Carla Maria, Boldorini, Renzo, Fresu, Luigia Grazia, Marengo, Emilio, Boccafoschi, Francesca“…In this study, we developed an in vitro model to characterize the role of mechanical stress as a potential trigger of endothelial deregulation in terms of inflammatory response bridging between endothelial cells (ECs), inflammatory cells, and matrix remodeling. …”
Publicado 2019
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29982“…Numerous studies have demonstrated the ability of HDL to promote the production of nitric oxide (NO) by endothelial cells (ECs) and to exert antiapoptotic and anti-inflammatory effects. …”
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29983“…This article is part of a Special Issue entitled: ECS Meeting edited by Claus Heizmann, Joachim Krebs and Jacques Haiech.…”
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29984“…CircAP2A2 knockdown or miR‐382‐5p overexpression decreased the proliferation, colony formation, migration, and invasion of HemECs and HUVEC cells. CONCLUSION: CircAP2A2 could promote proliferation and invasion of IH by regulating miR‐382‐5p/VEGFA axis.…”
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29985“…Collectively, our findings demonstrate for the first time that compound 9 is a promising antiangiogenic agent targeting both VEGF/VEGFR2 signaling in ECs and HIF-1α/VEGF pathway in tumor cells.…”
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29986“…The paper discusses the causes of thrombosis, the mechanism of blood clot formation, and factors such as hypoxia, the involvement of endothelial cells (ECs), and the activation of platelets and neutrophils along with the effects of bacteria and reactive oxygen species (ROS). …”
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29987por Solomon, Joseph, Hinther, Ashley, Matthews, T. Wayne, Nakoneshny, Steven C., Hart, Rob, Dort, Joseph C., Chandarana, Shamir P.“…RESULTS: Tumour size [HR:1.70(0.95–3.08)], nodal status [HR:2.15(1.00–4.64)], presence of extracapsular spread (ECS) [HR:6.36(2.41–16.74)] and smoking history [HR:2.87(1.19–6.86)] were associated with worsened RFS. …”
Publicado 2021
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29988“…Endocannabinoid system (ECS) has been identified ever since cannabinoid, an active substance of Cannabis, was known to interact with endogenous cannabinoid (endocannabinoid/eCB) receptors. …”
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29989“…This web-server is freely available for non-commercial users at https://kornmann.bioch.ox.ac.uk/leri/services/ecs.html, neither login nor e-mail required.…”
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29990Von Willebrand factor: A key glycoprotein involved in thrombo-inflammatory complications of COVID-19“…One of the pathophysiological features of COVID-19 is associated with the activation of vascular endothelial cells (ECs) leading to the disruption of vascular integrity, coagulation and inflammation. …”
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29991por Van den Bergh, Geoffrey, De Moudt, Sofie, Van den Branden, Astrid, Neven, Ellen, Leysen, Hanne, Maudsley, Stuart, De Meyer, Guido R. Y., D’Haese, Patrick, Verhulst, Anja“…The current study investigates cellular functioning and molecular pathways underlying AMC, respectively by, an ex vivo isometric organ bath set-up to explore the interaction between VSMCs and ECs and quantitative proteomics followed by functional pathway interpretation. …”
Publicado 2021
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29992por Zhang, Xintong, Zheng, Yu, Geng, Canru, Guan, Juntao, Wang, Lu, Zhang, Xiu, Cheng, Yihui, Li, Jian'an, Lu, Xiao“…Our results demonstrated that the IE group achieved superior improvement compared with the MI group in terms of left ventricular ejection fraction (LVEF), myocardial infarction size (MIS), arterial density (AD), monocytes (MNCs), smooth muscle cells (SMCs), endothelial cells (ECs), relative collateral blood flow (RCBF), MCP-1, and FGF-2 at the endpoint. …”
Publicado 2021
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29993“…MAIN TEXT: We sought to analyze the special nature of disagreements, conflicts and value uncertainties in prenatal medicine as well as the ways in which an ethics consultation service (ECS) could possibly respond to them and illustrated our results with a case example. …”
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29994por Pergolizzi, Simona, Alesci, Alessio, Centofanti, Antonio, Aragona, Marialuisa, Pallio, Socrate, Magaudda, Ludovico, Cutroneo, Giuseppina, Lauriano, Eugenia Rita“…Peripheral serotonin (5-HT), a bioactive amine predominantly produced by gut enterochromaffin cells (ECs), is crucial in gastrointestinal functions, including motility, sensitivity, secretion, and the inflammatory response. …”
Publicado 2022
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29995por Grismaldo Rodríguez, Adriana, Zamudio Rodríguez, Jairo A., Mendieta, Cindy V., Quijano Gómez, Sandra, Sanabria Barrera, Sandra, Morales Álvarez, Ludis“…Platelet-derived growth factor C stimulates angiogenesis and revascularization in ischemic tissues of diabetic mice and promotes the migration of progenitors and mature ECs to injury sites; however, the molecular mechanisms of its actions are not described yet. …”
Publicado 2022
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29996“…COVID-19 is characterized by progressive respiratory failure resulting from diffuse alveolar damage, inflammatory infiltrates, endotheliitis, and pulmonary and systemic coagulopathy forming obstructive microthrombi with multi-organ dysfunction, indicating that endothelial cells (ECs) play a central role in the pathogenesis of COVID-19. …”
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29997“…Here, we investigated the angiogenesis potential of human endothelial cells (ECs) upon exposure to hydrogen peroxide (H(2)O(2)), a cellular senescent factor. …”
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29998por Zhai, Jing, Navakkode, Sheeja, Yeow, Sean Qing Zhang, Krishna-K, Kumar, Liang, Mui Cheng, Koh, Joanne Huifen, Wong, Rui Xiong, Yu, Wei Ping, Sajikumar, Sreedharan, Huang, Hua, Soong, Tuck Wah“…Here, by genetic targeting to ablate Ca(V)1.3 RNA editing, we demonstrate that unedited Ca(V)1.3(ΔECS) mice exhibited improved learning and enhanced long-term memory, supporting a functional role of RNA editing in behavior. …”
Publicado 2022
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29999“…Tamoxifen-induced labeling of blood ECs at E9.5, before initiation of lymphatic development, traced most of the dermal LECs but with lower efficiency in the lumbar compared with the cervical skin. …”
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30000por Cui, Zhuang, Wu, Hangtian, Xiao, Ye, Xu, Ting, Jia, Junjie, Lin, Hancheng, Lin, Rongmin, Chen, Kun, Lin, Yihuang, Li, Kaiqun, Wu, Xiaohu, Li, Changjun, Yu, Bin“…A mouse model of OA with deletion of PDGFR-β in endothelial cells (ECs) exhibited fewer H-type vessels, ameliorated subchondral bone deterioration and alleviated overlying cartilage degeneration. …”
Publicado 2022
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