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30021por Schwerdtfeger, Jessica, Sauerwein, Helga, Albrecht, Elke, Mazzuoli-Weber, Gemma, von Soosten, Dirk, Dänicke, Sven, Kuhla, Björn“…In conclusion, the present study shows a tissue-specific AEA insensitivity and may point to a leptin-controlled regulation of the ECS in early-lactation.…”
Publicado 2023
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30022“…The discovery of the cognate receptor for tetrahydrocannabinol (THC) led to the classification of the endocannabinoid system (ECS) and the conjecture that phytocannabinoids might be “working” through this system. …”
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30023“…In rodent models, Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD) from the plant Cannabis sativa L. have shown anti-obesity properties, suggesting a link between the endocannabinoid system (ECS) and obesity. However, the oral administration route has rarely been studied in this context. …”
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30024“…A minimal necessary condition for preclinical studies to contribute to risk assessments of e-cigarettes (ECs) is the ability to expose laboratory animals to an appropriate dosage of aerosols. …”
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30025por Frolov, Alexey, Lobov, Arseniy, Kabilov, Marsel, Zainullina, Bozhana, Tupikin, Alexey, Shishkova, Daria, Markova, Victoria, Sinitskaya, Anna, Grigoriev, Evgeny, Markova, Yulia, Kutikhin, Anton“…Coherence of differentially expressed molecular categories in HCAECs and HITAECs suggests synergistic interactions between these ECs in a bypass surgery scenario.…”
Publicado 2023
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30026por Yang, Tao, Li, Guangxu, Li, Xifeng, Wei, Boyang, Su, Hengxian, Liu, Wenchao, Guo, Shenquan, Yang, Nan, Xu, Tao, Duan, Chuanzhi“…Furthermore, western blot analysis confirmed that the regenerated ECs were functional and the effect of DAPT was associated with increased expression of vascular endothelial growth factor receptor 2. …”
Publicado 2023
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30027Publicado 1984“…Since NAP-taurine prevents the conformational change from EClo to ECli , it must lock the system in the outward-facing form. …”
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30028por Bertrand, Julien Y., Chi, Neil C., Santoso, Buyung, Teng, Shutian, Stainier, Didier Y. R., Traver, David“…Recent reports have suggested that murine HSCs derive from hemogenic endothelial cells (ECs) lining the aortic floor1,2. Additional in vitro studies have similarly suggested that the hematopoietic progeny of ESCs arise through intermediates with endothelial potential3,4. …”
Publicado 2010
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30029por Amatschek, S, Lucas, R, Eger, A, Pflueger, M, Hundsberger, H, Knoll, C, Grosse-Kracht, S, Schuett, W, Koszik, F, Maurer, D, Wiesner, C“…RESULTS: We observed that tumour endothelial cells (ECs) secrete high levels of CXCL9 in all, and CXCL10 in most melanoma metastases. …”
Publicado 2011
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30030por Pallotta, Maria T., Orabona, Ciriana, Volpi, Claudia, Grohmann, Ursula, Puccetti, Paolo, Fallarino, Francesca“…We have also found that Suppressor of Cytokine Signaling 3 (SOCS3)—known to interact with phosphotyrosine-containing peptides and be selectively induced by interleukin 6 (IL-6)—binds mouse IDO, recruits the ECS (Elongin-Cullin-SOCS) E3 ligase, and targets the IDO/SOCS3 complex for proteasomal degradation. …”
Publicado 2010
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30031por Nassar, Zeyad D., Moon, Hyeongsun, Duong, Tam, Neo, LiQi, Hill, Michelle M., Francois, Mathias, Parton, Robert G., Parat, Marie-Odile“…We show that the conditioned medium of PTRF-expressing prostate cancer cells decreases ECs proliferation, migration and differentiation in vitro and ex vivo. …”
Publicado 2013
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30032por Soni, Manisha, Singh, Anil Kumar, Sharma, Shashi, Agarwal, Ankita, Gopalan, Natarajan, Rao, P. V. Lakshmana, Parida, Manmohan, Dash, Paban Kumar“…The nucleotide sequences of partial E1 gene of five representative CHIK viruses were deciphered, which revealed that all the viral strains from this outbreak belong to the recently emerging ECS African genotype. Identification of Chikungunya virus ECSA African genotype as the etiology of the present outbreak confirms the continued circulation of the novel genotype, since 2006, in India. …”
Publicado 2013
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30033“…In conclusion, our results demonstrated that PPARγ transcriptionally activated the expression of LPP1 gene in ECs, suggesting a potential role of PPARγ in the metabolism of phospholipids.…”
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30034por Carnevale, R., Loffredo, L., Nocella, C., Bartimoccia, S., Bucci, T., De Falco, E., Peruzzi, M., Chimenti, I., Biondi-Zoccai, G., Pignatelli, P., Violi, F., Frati, G.“…There is uncertainty about the precise role of polyphenols in interaction between platelets and endothelial cells (ECs). We aimed to investigate whether polyphenols are able to reduce endothelial activation induced by activated platelets. …”
Publicado 2014
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30035“…BP5 also suppressed submucosal DC maturation in the LPS-stimulated intestinal epithelial cells (ECs)/DCs coculture system. Finally, we found that heme oxygenase 1 (HO-1) was remarkably upregulated by BP5 in the LPS-induced DCs, and played an important role in the suppression of oxidative stress and DC maturation. …”
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30036por Sun, Fengjun, Yin, Zhe, Feng, Jiao, Qiu, Yefeng, Zhang, Defu, Luo, Wenbo, Yang, Huiying, Yang, Wenhui, Wang, Jie, Chen, Weijun, Xia, Peiyuan, Zhou, Dongsheng“…This is the first report of bla(NDM) in L. adecarboxylata and third report of this gene in R. ornithinolytica. pYNKP001-NDM is very similar to the IncN2 NDM-1-encoding plasmids pTR3, pNDM-ECS01, and p271A, whereas pP10164-NDM is similar to the IncFII(Y) bla(NDM-1)-carrying plasmid pKOX_NDM1. …”
Publicado 2015
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30037“…L1 overexpression in cultured endothelial cells of the lung (luECs) exerted a pleiotropic effect in that it regulated proliferation, migration, tubulogenesis, vascular permeability, and endothelial-to-mesenchymal transition (EndMT). …”
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30038por Wu, Yong, Hu, Zhiqing, Li, Zhuo, Pang, Jialun, Feng, Mai, Hu, Xuyun, Wang, Xiaolin, Lin-Peng, Siyuan, Liu, Bo, Chen, Fangping, Wu, Lingqian, Liang, Desheng“…Importantly, both F8 transcription and FVIII secretion were rescued in the candidate cell types for HA gene therapy including endothelial cells (ECs) and mesenchymal stem cells (MSCs) derived from the gene-corrected iPSCs. …”
Publicado 2016
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30039por Lu, Binger, Wang, Bin, Zhong, Shuping, Zhang, Yanmei, Gao, Fenfei, Chen, Yicun, Zheng, Fuchun, Shi, Ganggang“…Pretreatment of F(2) leads to a reduction in H/R injury, as evidenced by increased cell viability, decreased lactate dehydrogenase (LDH) leakage and apoptosis, together with enhanced AMP-activated protein kinase (AMPK) and liver kinase B1 (LKB1) phosphorylation in H/R ECs. Blockade of AMPK with compound C reversed F(2)-induced inhibition of H/R injury, as evidenced by decreased cell viability, increased LDH release and apoptosis. …”
Publicado 2016
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30040por Andersson, Hannah, Tullberg, Cecilia, Ahrné, Siv, Hamberg, Kristina, Lazou Ahrén, Irini, Molin, Göran, Sonesson, Mikael, Håkansson, Åsa“…Saliva was collected for cortisol analysis by Electrochemiluminescence Immunoassay (ECLI) and salivary IgA was analysed by Enzyme-Linked Immunosorbent Assay (ELISA). …”
Publicado 2016
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