“…Although the pathological features of AD consisting of amyloid-beta (Aβ) plaques in the extracellular space (ECS) and intracellular tau tangles are well established, the developed medicines targeting these two proteins have not obtained the expected clinical effects. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: Semi-structured qualitative interviews were conducted with 25 young adults ages 18–20 (M = 19) who smoked cigarettes daily or nearly every day and had used electronic cigarettes (ECs) on ≥ 2 occasions in their lifetime. RESULTS: Our results uncovered several themes: 1) The majority of teens experienced mental health disturbances as a result of the pandemic, which manifested as depression, anxiety, and/or acute loneliness due to social isolation; 2) tobacco purchasing behaviors sometimes changed, with both greater and less access reported among participants; 3) changes in tobacco use were also reported, with some reporting increases in use, others reporting decreases, and a few reporting quitting; and 4) while some youth reported that tobacco use could increase their risk related to COVID-19, the majority reported confusion and uncertainty about how tobacco use impacted their risk. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Upregulation of transient receptor potential melastatin 4 (TRPM4) in vascular endothelial cells (ECs) results in damage to capillaries and the blood-brain barrier (BBB), which is critical for the development of CE. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…After examining the two datasets, we discovered a protein with no unique features expressed when treated with glyphosate. The Ecs2020 model looks to be the most stable in structural modeling investigations, while the catalytic residues sought in drug development are anticipated. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In many organs, small openings across capillary endothelial cells (ECs) allow the diffusion of low–molecular weight compounds and small proteins between the blood and tissue spaces. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Over the pastyears, extensive research on primates, rodents, and humans has begun to clarify the effects of electroconvulsive seizures (ECS) and ECT on neurotransmission systems such the dopaminergic system. …”
Enlace del recurso
Enlace del recurso

“…Therefore, these new lines were named DEC cultured by liquid medium (ECS) and DEC cultured by bioreactor (ECB), respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In vitro treatment of cultured human aortic endothelial cells (ECs) with the 17-βE-loaded, CREKA-peptide-modified nanoemulsion system increased cellular nitrate/nitrite, indicating improved nitric oxide formation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Endothelium formed with endothelial cells (ECs) and their progenitors. Endothelial progenitor cells (EPCs) represent minor subpopulation of mononuclear cells in the blood. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Mild oxidation induced through BSO treatment facilitated the transition from embryogenic calluses (ECs) to somatic embryos. Meanwhile, auxin homeostasis was altered through the perturbation of ROS homeostasis by chemical treatments or suppression of ROS-scavenging proteins, along with the activating/suppressing the transcription of genes related to auxin transportation and signaling. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In opposite, BCP oxidation derivative, BCPO, does not exhibit CB (1/2) binding, thus the mechanism of its action is not related to endocannabinoid system (ECS) machinery. It is known that BCPO alters several key pathways for cancer development, such as mitogen‐activated protein kinase (MAPK), PI3K/AKT/mTOR/S6K1 and STAT3 pathways. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Copper-ionophore treatments [Cu(II)(gtsm), disulfiram & clioquinol] generated toxic levels of reactive oxygen species (ROS) in TRAMP adenocarcinoma cells, but not in normal mouse prostate epithelial cells (PrECs). Our results provide a basis for the pharmacological activity of copper-ionophores and suggest they are amendable for treatment of patients with prostate cancer. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULT: The T stage (P = .008), smoking history (P = .042), alcohol history (P = .048), need for radiotherapy (P = .012) and microscopic extracapsular spread (ECS) (P = .012) were associated with the TIL level. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Abbreviations: ACC = adrenocortical carcinoma, ACTH = Adrenocorticotropic Hormone, CD = Cushing’s disease, CS = Cushing’s syndrome, ECS = Ectopic Cushing’s syndrome, LA = laparoscopic adrenalectomy, OA = open adrenalectomy, PA = partial adrenalectomy, RA = robotic adrenalectomy, SCS = subclinical Cushing’ syndrome…”
Enlace del recurso
Enlace del recurso

“…Besides, this research provides an alternative cell model for penumbra ECs study.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This article is part of a Special Issue entitled: ECS Meeting edited by Claus Heizmann, Joachim Krebs and Jacques Haiech.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The aim of the present study was to determine whether granulocyte-colony stimulating factor (G-CSF) protects endothelial cells (ECs) and enhances angiogenesis in a rat model of hemorrhagic shock (HS) combined with cutaneous injury after resuscitation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The main aim of the present review was to collect evidence of the endo-cannabinoid system (ECS), cannabinoids toxicity, and the potential biotechnological approach of cannabinoids synthesis.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: AAV5 effectively infected vascular endothelial cells (ECs) and retinal pigment epithelial (RPE) cells; the ICAM2 promoter drove expression of GFP and SpCas9 in HRECs, but not in RPE cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso