“…The morphological results manifested that cells grow well in the gelatin/alginate hydrogels, and ASCs were differentiated into endothelial cells (ECs) and smooth muscle cells (SMCs), respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Coupled photocatalysis and membrane filtration has made PMRs suitable for application in the removal of emerging contaminants (ECs), such as diclofenac, carbamazepine, ibuprofen, lincomycin, diphenhydramine, rhodamine, and tamoxifen, from wastewater, while reducing the likelihood of byproducts being present in the permeate stream. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this report, we demonstrate that depletion of any of the three CCM genes or treatment with mPR-specific PRG actions (PRG/mifepristone) results in the disruption of the CmP signaling network, leading to increased permeability in the nPR(−) endothelial cells (ECs) monolayer in vitro. Finally, utilizing our in vivo hemizygous Ccm mutant mice models, we demonstrate that depletion of any of the three CCM genes, in combination with mPR-specific PRG actions, is also capable of leading to defective homeostasis of PRG in vivo and subsequent BBB disruption, allowing us to identify a specific panel of etiological blood biomarkers associated with BBB disruption. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Furthermore, vascular smooth muscle cells (VSMCs) and endothelial cells (ECs) participate in the neointima of MMD, but the etiology and pathophysiological changes in MMD vessels remain largely unknown. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As a critical member in wound healing, vascular endothelial cells (ECs) impaired under high levels of reactive oxygen species (ROS) would hamper neovascularization. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: Downregulation of Hpgd can improve the proliferation activity, reduce apoptosis, and enhance adhesion and angiogenesis in endothelial cells (ECs), thus promoting the occurrence and development of HPH. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Future studies can directly assay ECS activity in cART associated metabolic syndrome.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We identified twelve subclusters of VICs, four subclusters of ECs, six subclusters of lymphocytes, six subclusters of monocytic cells and one cluster of mast cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Because cell swelling, increased extracellular glutamate levels, and reduction of the brain extracellular space (ECS) all occur during seizure generation, we set out to determine whether VRACs are dysregulated throughout mesial temporal lobe epilepsy (MTLE), the most common form of adult epilepsy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our previous studies identified the crosstalk between the endothelial cells (ECs) and vascular smooth muscle cells (VSMCs), and the paracrine effect of VSMCs, which regulate the calcification of VSMCs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: The combination of the endocannabinoid system (ECS) and the type 2 cannabinoid receptor (CB2R) can activate various signal pathways, leading to distinct pathophysiological roles. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As cannabis is used at a higher rate in PWH compared to the general population, there is interest in understanding how HIV proteins and ART drugs interact with the endocannabinoid system (ECS) and inflammation in the CNS. Therefore, we investigated the effects of the HIV envelope protein gp120 and tenofovir alafenamide (TAF) on cannabinoid receptor 1 (CB(1)R), glial fibrillary acidic protein (GFAP), and IBA1 in the brain and on locomotor activity in mice. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…ECS (Elongin BC-Cul2/Cul5-SOCS-box protein) ubiquitin ligases recruit substrates to E2 ubiquitin-conjugating enzymes through a SOCS-box protein substrate receptor, an Elongin BC adaptor and a cullin (Cul2 or Cul5) scaffold which interacts with the RING protein. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Overactivity and/or dysregulation of the endocannabinoid system (ECS) contribute to development of obesity. In vitro studies indicate a regulatory role for the cannabinoid receptor 1 (CB(1)) in adipocyte function and CB(1)-receptor deficient (CB(1)(-/-)) mice are resistant to high fat diet-induced obesity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…When HLI was induced in mice that had received Tie2/LacZ BM transplantation, Ros treatment led a significantly larger amount of endothelial cells (ECs) of BM origin incorporated at ischemic sites than saline. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…GFAP, chemokine CXCL12, and connexin 43 (Cx43) were utilized as markers of radial glia cells, CD105 (endoglin) as a marker of angiogenically activated endothelial cells (ECs), and proteoglycan NG2 as a marker of immature pericytes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Endothelial progenitor cells (EPCs) play important roles in the regeneration of the vascular endothelial cells (ECs). Platelet-derived growth factor receptor (PDGFR)-β is known to contribute to proliferation, migration, and angiogenesis of EPCs, this study aims to investigate effects of transplantation of EPCs overexpressing PDGFR-β on vascular regeneration. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…TRIAL REGISTRATION: ChiCTR-ECS-14005052 (WHO international clinical trials register platform in China). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…More than one-third of the isolates harbored the F18, F4, astA, hlyA, estI, estII, elt, stx(2e), iha, orfA, orfB, paa, terE, ecs1763, or ureD virulence markers. In conclusion, although most isolates had a unique PFGE profile, a few particular combinations of phylogenetic groups, virulence genes and mutations in the sequenced genes involved in colistin resistance were identified on a number of occasions, suggesting the persistence of certain isolates over several years.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The interaction of (h)C5a with C5aR, previously hypothesized to involve a “two-site” binding, (i) recognition of the bulk of (h)C5a by the N-terminus (NT) of C5aR (“site1”), and (ii) recognition of C-terminus (CT) of (h)C5a by the extra cellular surface (ECS) of the C5aR (“site2”). However, the pharmacological landscapes of such recognition sites are yet to be illuminated at atomistic resolution. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso