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22361por Arend, Daniel, Junker, Astrid, Scholz, Uwe, Schüler, Danuta, Wylie, Juliane, Lange, Matthias“…PGP is registered as research data repository at BioSharing.org, re3data.org and OpenAIRE as valid EU Horizon 2020 open data archive. Above features, the programmatic interface and the support of standard metadata formats, enable PGP to fulfil the FAIR data principles—findable, accessible, interoperable, reusable. …”
Publicado 2016
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22362por Fahlenkamp, Astrid V., Stoppe, Christian, Cremer, Jan, Biener, Ingeborg A., Peters, Dirk, Leuchter, Ricarda, Eisert, Albrecht, Apfel, Christian C., Rossaint, Rolf, Coburn, Mark“…Further trials will be needed to address prophylaxis of xenon-induced nausea. TRIAL REGISTRATION: EU Clinical Trials EudraCT-2008-004132-20 ClinicalTrials.gov NCT00793663…”
Publicado 2016
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22363“…METHODS: Clinical trials were searched in the following databases: EudraCT (EU Drug Regulating Authorities Clinical Trials), ClinicalTrials.gov, and ICTRP (International Clinical Trials Registry Platform of the World Health Organization). …”
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22364por Gago Martínez, Andrea, Escontrela Rodriguez, Blanca, Planas Roca, Antonio, Martínez Ruiz, Alberto“…Consequently we consider appropriate that protocols for management of postoperative pain include IV-Ibuprofen 800 mg every 6 hours as an option to offer patients an analgesic benefit while reducing the potentially risks associated with morphine consumption. TRIAL REGISTRATION: EU Clinical Trials Register 2011-005007-33…”
Publicado 2016
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22365por Angelis, Aris, Kanavos, Panos, López-Bastida, Julio, Linertová, Renata, Oliva-Moreno, Juan, Serrano-Aguilar, Pedro, Posada-de-la-Paz, Manuel, Taruscio, Domenica, Schieppati, Arrigo, Iskrov, Georgi, Brodszky, Valentin, von der Schulenburg, Johann Matthias Graf, Chevreul, Karine, Persson, Ulf, Fattore, Giovanni“…BACKGROUND: The aim of this study was to determine the social/economic costs and health-related quality of life (HRQOL) of patients with epidermolysis bullosa (EB) in eight EU member states. METHODS: We conducted a cross-sectional study of patients with EB from Bulgaria, France, Germany, Hungary, Italy, Spain, Sweden and the United Kingdom. …”
Publicado 2016
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22366por Zhao, Jun-Wei, Li, Hai-Lou, Ma, Xing, Xie, Zhigang, Chen, Li-Juan, Zhu, Yongsheng“…By virtue of the stereochemical effect of the lone-electron pair located on the trigonal-pyramidal-AsO(3) groups and the one-pot self-assembly strategy in the conventional aqueous solution, a series of novel lanthanide-bridging and lone-electron-pair active trigonal-pyramidal-AsO(3) inducing nanosized poly(polyoxotungstate) aggregates [H(2)N(CH(3))(2)](6) Na(24)H(16){[Ln(10)W(16)(H(2)O)(30)O(50)](B-α-AsW(9)O(33))(8)}·97H(2)O [Ln = Eu(III) (1), Sm(III) (2), Gd(III) (3), Tb(III) (4), Dy(III) (5), Ho(III) (6), Er(III) (7), Tm(III) (8)] were prepared and further characterized by elemental analyses, IR spectra, UV spectra, thermogravimetric (TG) analyses and single-crystal X-ray diffraction. …”
Publicado 2016
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22367por De Vos, Daniel, Pirnay, Jean-Paul, Bilocq, Florence, Jennes, Serge, Verbeken, Gilbert, Rose, Thomas, Keersebilck, Elkana, Bosmans, Petra, Pieters, Thierry, Hing, Mony, Heuninckx, Walter, De Pauw, Frank, Soentjens, Patrick, Merabishvili, Maia, Deschaght, Pieter, Vaneechoutte, Mario, Bogaerts, Pierre, Glupczynski, Youri, Pot, Bruno, van der Reijden, Tanny J., Dijkshoorn, Lenie“…Multilocus sequence typing allocated them to clonal complex 1 corresponding to EU (international) clone I. Both strains caused consecutive outbreaks, interspersed with periods of apparent eradication. …”
Publicado 2016
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22368“…METHODS: Using the 2012 wave of Eurostat EU-SILC data for a set of 23 European countries, we estimate multilevel mixed-effects ordered logit models for self-assessed poor health (SAH) and self-reported limiting long-standing illnesses (LLS), and multilevel mixed-effects logit models for self-reported chronic illness (SC). …”
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22369“…Statistical analyses among groups within a region (US or EU) used column proportions test with a 95% confidence interval. …”
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22370por Gianoukakis, Andrew G, Flores, Natalia M, Pelletier, Corey L, Forsythe, Anna, Wolfe, Gregory R, Taylor, Matthew H“…METHODS: Data were collected from an online retrospective chart review study in the US and five European Union (EU) countries (France, Germany, Italy, Spain, and UK) with physicians recruited from an online panel. …”
Publicado 2016
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22371por Luciani, Mirella, Di Febo, Tiziana, Zilli, Katiuscia, Di Giannatale, Elisabetta, Armillotta, Gisella, Manna, Laura, Minelli, Fabio, Tittarelli, Manuela, Caprioli, Alfredo“…MAb 1E6G6 was selected and coupled to microbeads, then used for immuno-magnetic separation (IMS); the efficiency of the IMS method for E. coli O104:H4 isolation from milk was evaluated and compared to that of the EU RL VTEC conventional culture-based isolation procedure. …”
Publicado 2016
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22372por Moorkens, Evelien, Jonker-Exler, Clara, Huys, Isabelle, Declerck, Paul, Simoens, Steven, Vulto, Arnold G.“…Based on the literature search, recommendations can be made to overcome these barriers: (i) invest initially in advanced production processes with the help of single-use technology, experience or outsourcing (ii) gain experience with the regulatory process and establish alignment between stakeholders (iii) limit patent litigation, eliminate evergreening benefits, build out further the unitary patent and unified patent litigation system within the EU (iv) create demand-side policies, disseminate objective information (v) change attitude toward biosimilar switching/substitution, starting with physician, and patient education (vi) differentiate the biosimilar by service offerings, use an appropriate comparator in cost-effectiveness analyses. …”
Publicado 2016
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22373por Szpakowski, Rafał, Zając, Patrycja W., Dykowska, Grażyna, Sienkiewicz, Zofia, Augustynowicz, Anna, Czerw, Aleksandra“…BACKGROUND: According to data from the Organisation for Economic Cooperation and Development, Poland has one of the lowest numbers of nurses (5.2) per 1000 inhabitants among 28 EU countries. The migration of nurses from Poland has particular importance in the context of scarce human resources in this professional group, especially given the increasingly ageing population in European societies, which will entail an increased demand for nursing and care services. …”
Publicado 2016
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22374“…Finally, a total of 24,044 (44.19 %) unigenes were annotated at least in one database after BLAST search to NCBI non-redundant protein sequence, NCBI non-redundant nucleotide sequences, Kyoto Encyclopedia of Genes and Genomes (KEGG) Ortholog, manually annotated and reviewed protein sequence database (Swiss-Prot), Protein family, Gene Ontology, euKaryotic Ortholog Groups databases. After searching against the KEGG-GENE protein database, a result of 6228 (11.45 %) unigenes were assigned to 245 KEGG pathways. …”
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22375por Rossi, Settimio, Testa, Francesco, Melillo, Paolo, Orrico, Ada, Della Corte, Michele, Simonelli, Francesca“…Patients were treated with a single intravitreal injection of Ocriplasmin (Jetrea, Thrombogenics Inc, USA, Alcon/Novartis EU). The following outcome measures are considered: resolution of VMT, evaluated through the use of optical coherence tomography (SD-OCT), functional recovery evidenced by multifocal-electroretinogram (mfERG) and microperimetry (MP1) after treatment with Ocriplasmin. …”
Publicado 2016
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22376“…METHODS: We searched for ATMPs trials conducted between 1999 to June 2015 using three databases, which are Clinicaltrials.gov, the International Clinical Trials Registry Platform (ICTRP), and the EU Drug Regulating Authorities Clinical Trials (EudraCT). …”
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22377por Poscia, Andrea, Moscato, Umberto, La Milia, Daniele Ignazio, Milovanovic, Sonja, Stojanovic, Jovana, Borghini, Alice, Collamati, Agnese, Ricciardi, Walter, Magnavita, Nicola“…Within the framework of the EU-CHAFEA ProHealth65+ project, this paper aims to systematically review the literature on WHP interventions specifically targeted to older workers (OWs). …”
Publicado 2016
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22378por Shepherd, Victoria“…Future developments, such as the incoming EU Regulations, may address some of these differences, however the justification and level of risk permitted requires review to ensure that requirements are appropriate and proportionate to the burdens and risks for the individual, and also to the benefits for the wider population represented.…”
Publicado 2016
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22379por Hofmann, Frieder, Kruse-Plass, Maren, Kuhn, Ulrike, Otto, Mathias, Schlechtriemen, Ulrich, Schröder, Boris, Vögel, Rudolf, Wosniok, Werner“…The recorded levels are more than a single degree of magnitude larger than actual EU expert risk assessment assumptions. Because variation and total aggregation of deposited pollen on leaves have been previously underestimated, lepidopteran larvae have actually been subjected to higher and more variable exposure. …”
Publicado 2016
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22380“…North–south research partnerships have contributed significantly to enhancing the research capacity in low- and middle-income countries (LMICs) over the past few decades; however, a lack of skilled researchers to inform health policy development persists, particularly in LMICs. The EU FP7 funded African/Asian Regional Capacity Development (ARCADE) projects were multi-partner consortia aimed to develop a new generation of highly trained researchers from universities across the globe, focusing on global health-related subjects: health systems and services research and research on social determinants of health. …”
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