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  1. 22461
    “…Thus, Alu elements, which are characterized by euchromatic chromatin features, are repaired and replicated the earliest, followed by LINE-1 elements, including more variegated eu/heterochromatic features and, lastly, satellite tandem repeats, which are homogeneously characterized by heterochromatic features and extend over megabase-long genomic regions. …”
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    DNA replication and repair kinetics of Alu, LINE-1 and satellite III genomic repetitive elements
  2. 22462
    “…Despite these established facts and positive experiences from EU neighboring countries like the Netherlands or the United Kingdom, Germany has not yet implemented store-and-forward teledermatology in routine care. …”
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    Improving cooperation between general practitioners and dermatologists via telemedicine: study protocol of the cluster-randomized controlled TeleDerm study
  3. 22463
    “…This raises the question about the presence and relation with clinical outcome of low EpCAM expressing CTC (EpCAM(low) CTC). In the EU-FP7 CTC-Trap program, we investigated the presence of EpCAM(high) and EpCAM(low) CTC using CellSearch, followed by microfiltration of the EpCAM(high) CTC depleted blood. …”
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    EpCAM(high) and EpCAM(low) circulating tumor cells in metastatic prostate and breast cancer patients
  4. 22464
    “…Conclusions: Access to reimbursed orphan drugs varies significantly across EU countries. The highest, substantial agreement in reimbursement decisions was observed between Italy and Spain and the lowest between Germany and England. …”
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    Reimbursement of Orphan Drugs in Europe in Relation to the Type of Authorization by the European Medicines Agency and the Decision Making Based on Health Technology Assessment
  5. 22465
    “…A series of rare earth complexes of the form Ln(L(R))(3) supported by bidentate ortho-aryloxide–NHC ligands are reported (L(R) = 2-O-3,5-(t)Bu(2)-C(6)H(2)(1-C{N(CH)(2)N(R)})); R = (i)Pr, (t)Bu, Mes; Ln = Ce, Sm, Eu). The cerium complexes cleanly and quantitatively insert carbon dioxide exclusively into all three cerium carbene bonds, forming Ce(L(R)·CO(2))(3). …”
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    Selective and catalytic carbon dioxide and heteroallene activation mediated by cerium N-heterocyclic carbene complexes
  6. 22466
    por Kiely, Mairead, Cashman, Kevin D.
    Publicado 2018
    “…In a study of almost 56,000 individuals, the first internationally standardised dataset of vitamin D status showed that 13% of EU residents overall, across a latitude gradient of 35° N to 69° N, had serum 25(OH)D < 30 nmol/L and 40% were < 50 nmol/L. …”
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    Summary Outcomes of the ODIN Project on Food Fortification for Vitamin D Deficiency Prevention
  7. 22467
    “…The most immediate application is related to the scope of the research project that frames this work (http://www.mycyfapp.eu). These results have contributed to the development of a mobile app for cystic fibrosis patients, which includes an algorithm for enzyme dose prediction based on food properties. …”
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    In Vitro Digestion of Lipids in Real Foods: Influence of Lipid Organization Within the Food Matrix and Interactions with Nonlipid Components
  8. 22468
    “…As a consequence, the industrial production of chickens with a poor microbial profile leads to enteric microbial infestation and infectious disease outbreaks, which became even more prevalent after the withdrawal of antibiotic growth promoters on many world markets (e.g., the EU). This review presents the rationale, methodology and life-long effects of in ovo stimulation of chicken microflora. …”
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    Prebiotics and synbiotics – in ovo delivery for improved lifespan condition in chicken
  9. 22469
    “…For 24 h signal drift, noise and the influences of a cordless telephone (Ascom d43 DECT Handset, EU DECT 1880–1900 MHz, Ascom Wireless, Baar, Switzerland), a smartphone (Sony Xperia Go ST27i, Sony Corporation, Tokyo, Japan) and a computer (Hewlett-Packard ProBook 650 15,6″ - D9S33AV, Hewlett-Packard Inc., Palo Alto, USA) on the measuring profile were analysed. …”
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    The influence of electromagnetic radiation on the measurement behaviour of the triggerfish® contact lens sensor
  10. 22470
    “…We observed anti-measles, anti-mumps, and anti-rubella antibody GMCs of 1790.2 mIU/mL, 113.5 EU/mL, and 76.1 IU/mL, respectively, and SRRs of 98.8%, 98.4%, and 99.5%, respectively, after a dose of MMR-RIT; non-inferiority compared to MMR II was demonstrated. …”
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    Immunogenicity and safety of a second dose of a measles-mumps-rubella vaccine administered to healthy participants 7 years of age or older: A phase III, randomized study
  11. 22471
    “…Serious adverse events may be less frequent with reduced doses. TRIAL REGISTRATION: EU Clinical Trials Registry, EudraCT 2011–005871-18 and ClinicalTrials.gov, NCT01604629. …”
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    Non-inferiority of dose reduction versus standard dosing of TNF-inhibitors in axial spondyloarthritis
  12. 22472
    “…Culturally competent curricula and teachers are needed, to ensure cultural competence among medical doctors and to tackle inequalities in health between different ethnic groups. The objective of this EU financed study is therefore to provide a snapshot of the role of cultural competence in European medical educational programmes. …”
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    Need for ensuring cultural competence in medical programmes of European universities
  13. 22473
    “…This trial was registered at the EU Clinical Trials Register (EudraCT 2011-004890-10) and the ISRCTN Registry (ISRCTN35648481).…”
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    Randomized controlled trial of vitamin D supplementation in older people to optimize bone health
  14. 22474
    “…Also, the cut-off values of PT, FHA, and PRN were 11.65, 38.95, and 5.66 EU/mL, respectively. The distributions of antibody levels in paired showed that 93.15% (68/73) in anti-PT IgG, 97.26% (72/73) in anti-FHA IgG, and 100% in anti-PRN IgG were higher than a 100% increase after vaccination. …”
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    Development and implementation of standardized method for detecting immunogenicity of acellular pertussis vaccines in Korea
  15. 22475
    “…Predicted HR-QOL was combined with prevalence data from the Global Burden of Disease Study (GBD) to estimate met need and the causes of unmet need due to morbidity in the US and EU5 for five diseases: rheumatoid arthritis, breast cancer, Parkinson’s disease, hepatitis C, and chronic obstructive pulmonary disease (COPD). …”
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    An empirical tool for estimating the share of unmet need due to healthcare inefficiencies, suboptimal access, and lack of effective technologies
  16. 22476
    “…This study was registered with the EU Clinical Trials Register, EudraCT number 2011-002545-35, and with the ISRCTN registry, number 43327231.…”
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    Paclitaxel with or without trametinib or pazopanib in advanced wild-type BRAF melanoma (PACMEL): a multicentre, open-label, randomised, controlled phase II trial
  17. 22477
    “…The internal biosecurity score was lower and had greater variability among farms than other EU countries. Using multivariable linear regression, the biosecurity practices explained 8, 23, and 16% of variability in piglet mortality, finisher mortality, and average daily gain, respectively. …”
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    Using the Biocheck.UGent™ scoring tool in Irish farrow-to-finish pig farms: assessing biosecurity and its relation to productive performance
  18. 22478
    “…BACKGROUND: Mobile Therapeutic Attention for Patients with Treatment-Resistant Schizophrenia (m-RESIST) is an EU Horizon 2020-funded project aimed at designing and validating an innovative therapeutic program for treatment-resistant schizophrenia. …”
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    Mobile Phone and Wearable Sensor-Based mHealth Approaches for Psychiatric Disorders and Symptoms: Systematic Review
  19. 22479
    “…The resulting ZIKV scanning microarray chips were used to screen three pools of sera from recent Zika outbreaks in Senegal and Cape Verde, in Brazil, and from overseas travelers returning to the EU. Together with a mixed pool of well characterized, archived sera of patients suffering from infections by dengue, yellow fever, tick-borne encephalitis, and West Nile viruses, a total of 42 sera went into the study. …”
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    Diagnosing Zika virus infection against a background of other flaviviruses: Studies in high resolution serological analysis
  20. 22480
    “…All developed models were applied to predict 80,086 EU REACH substances. The rational and random final models had 63.1% and 56.9% coverage of the REACH set, respectively, and predicted 1,256 and 3,214 substances as actives. …”
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    QSAR modelling of a large imbalanced aryl hydrocarbon activation dataset by rational and random sampling and screening of 80,086 REACH pre-registered and/or registered substances
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