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23161Measurement properties of the EQ-5D across four major geriatric conditions: Findings from TOPICS-MDSpor Lutomski, Jennifer E., Krabbe, Paul F. M., Bleijenberg, Nienke, Blom, Jeanett, Kempen, Gertrudis I. J. M., MacNeil-Vroomen, Janet, Muntinga, Maaike E., Steyerburg, Ewout, Olde-Rikkert, Marcel G. M., Melis, René J. F.“…METHODS: The study sample comprised 25,637 community-dwelling persons aged 65 years and older residing in the Netherlands (Data source: TOPICS-MDS, www.topics-mds.eu). Floor and ceiling effects were examined. To assess convergent validity, random effects meta-correlations (Spearman’s rho) were derived between individual EQ-5D domains and related survey items. …”
Publicado 2017
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23162por Annemans, Lieven, Aymé, Ségolène, Le Cam, Yann, Facey, Karen, Gunther, Penilla, Nicod, Elena, Reni, Michele, Roux, Jean-Louis, Schlander, Michael, Taylor, David, Tomino, Carlo, Torrent-Farnell, Josep, Upadhyaya, Sheela, Hutchings, Adam, Le Dez, Lugdivine“…The introduction of the EU Regulation on orphan medicinal products (OMP) has been successful in stimulating investment in the research and development of OMPs. …”
Publicado 2017
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23163“…The study population was divided into 3 groups based on country of birth: (1) Sweden, (2) immigrants from ‘Western’ countries (EU25, Norway, Iceland, North America and Oceania) and (3) immigrants from ‘non-Western’ countries (east Europe, Africa, Asia and South America). …”
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23164“…Smoking is the leading, preventable death-cause worldwide, being responsible for almost 650,000 deaths in the E.U. annually. A combination of pharmacological interventions, including nicotine replacement therapy, bupropion and varenicline, and behavioural support is the most effective approach to smoking cessation. …”
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23165por Fridman, Moshe, Banaschewski, Tobias, Sikirica, Vanja, Quintero, Javier, Chen, Kristina S“…Caregivers reported experiences of obtaining an ADHD diagnosis, access to BT, availability of caregiver resources, and level of health care/school support. Pan-EU and country-specific descriptive statistics are reported; responses were compared across countries. …”
Publicado 2017
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23166por Laaksonen, Petteri, Sinkkonen, Aki, Zaitsev, Gennadi, Mäkinen, Esa, Grönroos, Timo, Romantschuk, Martin“…After an initial adaption time, the reductions in BOD and chemical oxygen demand were constantly between 92 and 98%, showing that the biological degradation process in the filters functioned optimally and clearly comply with the national and EU standards. The reduction in total nitrogen and total phosphorus, however, reached required levels only during the first months of testing, apparently when buildup of microbial biomass was still ongoing. …”
Publicado 2017
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23167por Farkas, Andreas M., Mariz, Segundo, Stoyanova-Beninska, Violeta, Celis, Patrick, Vamvakas, Spiros, Larsson, Kristina, Sepodes, Bruno“…We analyzed several parameters associated with active ATMP ODDs focusing on sponsor type and EU-Member State origin, therapeutic area targeted, and ATMP classification [i.e., somatic cell therapy medicinal product, tissue-engineered product (TEP), or gene therapy medicinal product (GTMP)] and the use of regulatory services linked to incentives such as the use of protocol assistance (PA) and other Committees [Committee for Advanced Therapies (CAT) and the Pediatric Committee]. …”
Publicado 2017
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23168por Thonberg, Håkan, Chiang, Huei-Hsin, Lilius, Lena, Forsell, Charlotte, Lindström, Anna-Karin, Johansson, Charlotte, Björkström, Jenny, Thordardottir, Steinunn, Sleegers, Kristel, Van Broeckhoven, Christine, Rönnbäck, Annica, Graff, Caroline“…Furthermore, a third SORL1 variant, c.5195G > C, recently identified in a Swedish case control cohort included in the European Early-Onset Dementia (EU EOD) consortium study, was detected in two affected siblings in a third family with familial EOAD. …”
Publicado 2017
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23169por Albiñana, Virginia, Escribano, Rosa María Jiménez, Soler, Isabel, Padial, Luis Rodríguez, Recio-Poveda, Lucia, Villar Gómez de las Heras, Karina, Botella, Luisa María“…TRIAL REGISTRATION: The study has a clinical trial design and was registered at EU Clinical Trials Register and Spanish Clinical Studies Registry, EudraCT Number: 2014–003671-30. …”
Publicado 2017
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23170“…TRIAL REGISTRATION: CLARINET EU Clinical Trials Register Number, 2005–004904-35.…”
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23171por Bozicevic, Ivana, Handanagic, Senad, Cakalo, Jurja Ivana, Rinder Stengaard, Annemarie, Rutherford, George“…OBJECTIVE: The study aims to describe the results of the assessment of the needs for further development of capacities in HIV strategic information systems in the non-European Union (EU) countries in the World Health Organization European Region (EUR). …”
Publicado 2017
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23172“…The Kerry spotted slug Geomalacus maculosus Allman, an EU protected species, exhibits two distinct phenotypes: brown individuals occur in forested habitats whereas black animals live in open habitats such as blanket bog. …”
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23173por Lassen, Martin L., Muzik, Otto, Beyer, Thomas, Hacker, Marcus, Ladefoged, Claes Nøhr, Cal-González, Jacobo, Wadsak, Wolfgang, Rausch, Ivo, Langer, Oliver, Bauer, Martin“…Clinical Trial Registration: www.clinicaltrialsregister.eu, identifier 2013-001724-19…”
Publicado 2017
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23174por Meyers, Kristin J., Upadhyaya, Himanshu P., Landry, John L., Chhabra-Khanna, Rashna, Falk, Deborah M., Seetharama Rao, Balasubramanya, Jones, Meghan E.“…The protocol and final study report for this European Union regulatory commitment are publicly accessible via the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP) European Union PASS Register (www.encepp.eu/encepp/viewResource.htm?id=16847). The current manuscript describes the results within the final study report. …”
Publicado 2017
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23175“…Animal welfare standards have been incorporated in EU legislation and in farm assurance schemes, based on scientific information and aiming to safeguard the welfare of the species concerned. …”
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23176“…Caution may be needed not only for drugs with novel MOAs, but also for drugs for which local dose-finding studies have been skipped, expedited review status has been given, timing of launch is close to those in the USA and the EU, and spontaneous reports rather than company-lead surveillance suggest possible safety risks.…”
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23177“…BACKGROUND: The United Nations General Assembly (UNGA), the International Labour Organization (ILO), the World Health Organization (WHO), the International Commission on Occupational Health (ICOH), and the European Union (EU) have encouraged countries to organize occupational health services (OHS) for all working people irrespective of the sector of economy, size of enterprise or mode of employment of the worker. …”
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23178Choice of implant combinations in total hip replacement: systematic review and network meta-analysispor López-López, José A, Humphriss, Rachel L, Beswick, Andrew D, Thom, Howard H Z, Hunt, Linda P, Burston, Amanda, Fawsitt, Christopher G, Hollingworth, William, Higgins, Julian P T, Welton, Nicky J, Blom, Ashley W, Marques, Elsa M R“…Data sources Medline, Embase, The Cochrane Library, ClinicalTrials.gov, WHO International Clinical Trials Registry Platform, and the EU Clinical Trials Register. Review methods Published randomised controlled trials comparing different implant combinations. …”
Publicado 2017
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23179por Grob, Jean-Jacques, Mortier, Laurent, D’Hondt, Lionel, Grange, Florent, Baurain, Jean Francois, Dréno, Brigitte, Lebbe, Céleste, Robert, Caroline, Dompmartin, Anne, Neyns, Bart, Gillet, Marc, Louahed, Jamila, Jarnjak, Silvija, Lehmann, Frédéric F“…Postdose 4, all patients were seropositive for MAGE-A3-specific antibodies, with a geometric mean titre of 2778.7 ELISA units (EU)/mL (95% CI 1638.3 to 4712.8). One complete and three partial responses were reported (only in GS+ patients). …”
Publicado 2017
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23180por Yadav, Rahul, Hama, Salam, Liu, Yifen, Siahmansur, Tarza, Schofield, Jonathan, Syed, Akheel A., France, Michael, Pemberton, Philip, Adam, Safwaan, Ho, Jan Hoong, Aghamohammadzadeh, Reza, Dhage, Shaishav, Donn, Rachelle, Malik, Rayaz A., New, John P., Jeziorska, Maria, Durrington, Paul, Ammori, Basil A., Soran, Handrean“…term=paraoxonase&cntry1=EU%3AGB&rank=1.…”
Publicado 2017
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