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  1. 23641
    “…It is noteworthy that the Podwiśniówka acid pit lake and Wiśniówka Duża acid pit sump exhibit different element signatures and REE concentration patterns normalized to North American Composite Shale (NASC): the Podwiśniówka acid pit lake always shows a characteristic roof-shaped medium REE (MREE) profile with distinct enrichments in Gd, Eu, and Tb whereas the other one displays a step-shaped heavy REE (HREE) profile with positive Tb and Gd anomalies. …”
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    Rare earth and trace element signatures for assessing an impact of rock mining and processing on the environment: Wiśniówka case study, south-central Poland
  2. 23642
    “…Recent Control Banding (CB) tools use the classifications of the United Nations Global Harmonized System (UN GHS) or the European Union Classifications, Labelling and Packaging (EU CLP) which are grouped over 5 HBs. The use of CB is growing worldwide for the risk control of substances without an Occupational Exposure Limit Value (OELV). …”
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    On the Strength and Validity of Hazard Banding
  3. 23643
    “…METHODS: As part of the EU project ‘Suicidality: Treatment Occurring in Paediatrics’ (STOP project), we developed web-based Patient Reported Outcome Measures (PROMs) for children and adolescents and for proxy reports by parents and clinicians in order to assess suicidality. …”
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    Development and psychometric properties of the Suicidality: Treatment Occurring in Paediatrics (STOP) Suicidality Assessment Scale (STOP-SAS) in children and adolescents
  4. 23644
    “…The multivariable logistic regression model identified the following determinants with a robust, statistically significant association with publication: phase 2 (60% published; adjusted OR 2.6, 95% CI 1.1–5.9), phase 3 (73% published; adjusted OR 4.1, 95% CI 1.7–10.0), and trials not belonging to phase 1–4 (60% published; adjusted OR 3.2, 95% CI 1.5 to 6.5) compared to phase 1 trials (35% published); trials with a company or investigator as applicant (63% published) compared to trials with a Contract Research Organization (CRO) as applicant (50% published; adjusted OR 1.7; 95% CI 1.1–2.8); and multicenter trials also conducted in other EU countries (68% published; adjusted OR 2.2, 95% CI 1.1–4.4) or also outside the European Union (72% published; adjusted OR 2.0, 95% CI 1.0–4.0) compared to single-center trials (45% published). …”
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    Non-Publication Is Common among Phase 1, Single-Center, Not Prospectively Registered, or Early Terminated Clinical Drug Trials
  5. 23645
    “…SwitchFinder is freely available at https://newbioinformatics.eu/switchfinder. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12859-016-1391-0) contains supplementary material, which is available to authorized users.…”
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    SwitchFinder – a novel method and query facility for discovering dynamic gene expression patterns
  6. 23646
    “…The entire manufacturing process, as well as the subsequent quality control of the final cell product (CP), were realized on-site and in compliance with EU guidelines for Good Manufacturing Practice. The biological activity of automatically isolated CD133(+) cells was evaluated and compared to manually isolated CD133(+) cells via functional assays as well as immunofluorescence microscopy. …”
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    GMP-conformant on-site manufacturing of a CD133(+) stem cell product for cardiovascular regeneration
  7. 23647
    “…The trial coordinating centre continues to engage with physicians about their uncertainty. TRIAL REGISTRATION: EU Clinical Trials, EudraCT 2012-003190-26. Registered on 3 July 2012.…”
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    Reasons for non-recruitment of eligible patients to a randomised controlled trial of secondary prevention after intracerebral haemorrhage: observational study
  8. 23648
    “…BACKGROUND: The Eurolight project assessed the impact of headache disorders in ten EU countries, using the same structured questionnaire but varying sampling methods. …”
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    Prevalence and burden of headache disorders in Lithuania and their public-health and policy implications: a population-based study within the Eurolight Project
  9. 23649
    “…Clinical Trial Registration: EU clinical trials register EudraCT number 2013-005334-37 and ClinicalTrials.gov NCT02168491. …”
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    Switch to Combined GLP1 Receptor Agonist Lixisenatide with Basal Insulin Glargine in Poorly Controlled T2DM Patients with Premixed Insulin Therapy: A Clinical Observation and Pilot Study in Nine Patients
  10. 23650
    “…BACKGROUND: In 2006, the European Union (EU) has decided to forbid use of antibiotics as growth promoters. …”
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    Effect of Dietary sugar beet pulp supplementation on growth performance, nutrient digestibility, fecal Microflora, blood profiles and Diarrhea incidence in weaning pigs
  11. 23651
    Publicado 2017
    “…FUNDING: UK Medical Research Council, UK Department for International Development, EU EDCTP2 programme.…”
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    Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies
  12. 23652
    “…The SAP for the PEDOCELL trial was developed a priori in order to minimise analysis bias. TRIAL REGISTRATION: EU Clinical Trials Register (EudraCT number: 2016-001528-69). …”
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    The Penicillin for the Emergency Department Outpatient treatment of CELLulitis (PEDOCELL) trial: update to the study protocol and detailed statistical analysis plan (SAP)
  13. 23653
    “…BACKGROUND: Surgical castration is still practiced in many EU countries to avoid undesirable aggressive behavior and boar taint in male pigs. …”
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    Surgical castration with pain relief affects the health and productive performance of pigs in the suckling period
  14. 23654
    “…However, two factors suggest that a different approach to written consent should be investigated for low-risk pRCTs: a) a substantial minority of respondents supported general notification, b) data from the US have shown that most patients who prefer written consent are willing to forego it if obtaining written consent makes the trial too difficult to be conducted; and c) 2016 CIOMS guidelines endorse waivers of consent when the trial fulfills specific conditions. Surveys in other EU countries are needed to assess what patients believe towards pRCTs. …”
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    Patients’ beliefs regarding informed consent for low-risk pragmatic trials
  15. 23655
    “…ABSTRACT: It is our concern that European Union Directive 2010/63/EU with its current project evaluation of animal research in the form of a harm–benefit analysis may lead to an erosion of the credibility of research. …”
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    The Road to Hell Is Paved with Good Intentions: Why Harm–Benefit Analysis and Its Emphasis on Practical Benefit Jeopardizes the Credibility of Research
  16. 23656
    “…DISCUSSION: The TAILOR trial will contribute knowledge about the effect of tapering/discontinuation of antipsychotic medication in the early phases of schizophrenia and related disorders and the results may guide future clinical treatment regimens of antipsychotic treatment. TRIAL REGISTRATION: EU Clinical Trials Register – EudraCT number: 2016-000565-23. …”
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    TAILOR – tapered discontinuation versus maintenance therapy of antipsychotic medication in patients with newly diagnosed schizophrenia or persistent delusional disorder in remission of psychotic symptoms: study protocol for a randomized clinical trial
  17. 23657
    “…IMS Health’s MIDAS database has been used for sales data (converted to Defined Daily Doses/1000 inhabitants/day) for the case study medications from the market authorization date in 2004 until December 2009 for 23 EU member states. RESULTS: Consumption of the case study medications was seen in all countries. …”
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    Variability in market uptake of psychotropic medications in Europe reflects cultural diversity
  18. 23658
    “…In collaboration with the European Cancer Patient Coalition (ECPC), the trial results will be disseminated through publications in scientific journals, presentations at international conferences, and postings on the eSMART website and other relevant clinician and consumer websites; establishment of an eSMART website (www.esmartproject.eu) with publicly accessible general information; creation of an eSMART Twitter Handle, and production of a toolkit for implementing/utilising the ASyMS technology in a variety of clinical practices and other transferable health care contexts. …”
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    The eSMART study protocol: a randomised controlled trial to evaluate electronic symptom management using the advanced symptom management system (ASyMS) remote technology for patients with cancer
  19. 23659
    “…According to average annual levels of fine particulate matter (PM2.5, ambient particles with aerodynamic diameter of 2.5 μm or less) presented in the urban air quality database issued by WHO in 2016, as many as 33 Polish cities are among the 50 most polluted cities in the European Union (EU), with Silesian cities topping the list. The aim of this study was to characterize the indoor air quality in Silesian kindergartens based on the concentrations of gaseous compounds (SO(2), NO(2)), PM2.5, and the sum of 15 PM2.5-bound polycyclic aromatic hydrocarbons (PAHs), including PM2.5-bound benzo(a)pyrene (BaP), as well as the mutagenic activity of PM2.5 organic extracts in Salmonella assay (strains: TA98, YG1024). …”
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    Indoor air quality in urban and rural kindergartens: short-term studies in Silesia, Poland
  20. 23660
    “…EudraCT: EudraCT: 2009-011602-42 (https://www.clinicaltrialsregister.eu/).…”
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    Effect of MRI on preterm infants and their families: a randomised trial with nested diagnostic and economic evaluation
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