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23981por Haeseler, Gertrud, Schaefers, Dirk, Prison, Natalie, Ahrens, Jörg, Liu, Xiaofei, Karch, Annika“…TRIAL REGISTRATION: https://eudract.ema.europa.eu (EudraCT- Nr. 2011–003238-15); October 24th, 2012.…”
Publicado 2017
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23982por Winther, Stine Braendegaard, Österlund, Pia, Berglund, Åke, Glimelius, Bengt, Qvortrup, Camilla, Sorbye, Halfdan, Pfeiffer, Per“…Furthermore it may provide understanding of efficacy and tolerability of chemotherapy in older cancer patients and thus offer a better chance for tailored treatment strategies in these patients. TRIAL REGISTRATION: EU Clinical Trial Register, EudraCT no. 2014–000394-39. …”
Publicado 2017
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23983por Severson, Tesa M., Wolf, Denise M., Yau, Christina, Peeters, Justine, Wehkam, Diederik, Schouten, Philip C., Chin, Suet-Feung, Majewski, Ian J., Michaut, Magali, Bosma, Astrid, Pereira, Bernard, Bismeijer, Tycho, Wessels, Lodewyk, Caldas, Carlos, Bernards, René, Simon, Iris M., Glas, Annuska M., Linn, Sabine, van ‘t Veer, Laura“…METHODS: A diagnostic gene expression signature (BRCA1ness) was developed using a centroid model with 128 triple-negative breast cancer samples from the EU FP7 RATHER project. This BRCA1ness signature was then tested in HER2-negative patients (n = 116) from the I-SPY 2 TRIAL who received an oral PARP inhibitor veliparib in combination with carboplatin (V-C), or standard chemotherapy alone. …”
Publicado 2017
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23984por Dósa, Edit, Heltai, Krisztina, Radovits, Tamás, Molnár, Gabriella, Kapocsi, Judit, Merkely, Béla, Fu, Rongwei, Doolittle, Nancy D., Tóth, Gerda B., Urdang, Zachary, Neuwelt, Edward A.“…Clinical Trial Registration URL: https://eudract.ema.europa.eu. Unique identifier: 2011-000887-92…”
Publicado 2017
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23985por Nishikitani, Mariko, Nakao, Mutsuhiro, Tsurugano, Shinobu, Inoure, Mariko, Yano, Eiji“…This interval time was based on EU regulations and the goal set by the government of Japan. …”
Publicado 2017
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23986por Turuspekov, Yerlan, Baibulatova, Aida, Yermekbayev, Kanat, Tokhetova, Laura, Chudinov, Vladimir, Sereda, Grigoriy, Ganal, Martin, Griffiths, Simon, Abugalieva, Saule“…However, it was found that EU and CIMMYT germplasm has high breeding potential to improve yield performance in Central and Southern regions. …”
Publicado 2017
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23987por Grellier, James, White, Mathew P, Albin, Maria, Bell, Simon, Elliott, Lewis R, Gascón, Mireia, Gualdi, Silvio, Mancini, Laura, Nieuwenhuijsen, Mark J, Sarigiannis, Denis A, van den Bosch, Matilda, Wolf, Tanja, Wuijts, Susanne, Fleming, Lora E“…Other knowledge and tools developed in the project will be made available via the project website (www.bluehealth2020.eu). Project results will ultimately provide key inputs to planning and policy relating to blue space, further stimulating the integration of environmental and health considerations into decision-making, such that blue infrastructure is developed across Europe with both public health and the environment in mind.…”
Publicado 2017
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23988por Martin, Jessica E., Sandilands, Victoria, Sparrey, Julian, Baker, Laurence, McKeegan, Dorothy E. F.“…ABSTRACT: Urgent development of alternative on-farm killing methods for poultry is required following the number restrictions placed on the use of traditional manual cervical dislocation by European Legislation (EU 1099/2009). Alternatives must be proven to be humane and, crucially, practical in commercial settings with multiple users. …”
Publicado 2018
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23989“…The lipid produced by M. buryatense was estimated to have a cetane number of 75, which is 50% higher than biofuel standards requested by US and EU. CONCLUSIONS: Cell growth and lipid production were significantly influenced by culture conditions for both 5GB1 and AP18. …”
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23990por Talbot, Pauline, Radziwill-Bienkowska, Joanna M., Kamphuis, Jasper B. J., Steenkeste, Karine, Bettini, Sarah, Robert, Véronique, Noordine, Marie-Louise, Mayeur, Camille, Gaultier, Eric, Langella, Philippe, Robbe-Masselot, Catherine, Houdeau, Eric, Thomas, Muriel, Mercier-Bonin, Muriel“…BACKGROUND: Titanium dioxide (TiO(2)) particles are commonly used as a food additive (E171 in the EU) for its whitening and opacifying properties. …”
Publicado 2018
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23991por Blin, Patrick, Demoly, Pascal, Drouet, Martine, Falissard, Bruno, Lignot-Maleyran, Séverine, Maizi, Hélène, Lorrain, Simon, Lassalle, Régis, Droz-Perroteau, Cécile, Moore, Nicholas, Molimard, Mathieu“…Not prospectively registered. http://www.encepp.eu/encepp/viewResource.htm?id=16229 ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13223-018-0262-9) contains supplementary material, which is available to authorized users.…”
Publicado 2018
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23992por Li, Yawen, Hamlin, Donald K., Chyan, Ming-Kuan, Wong, Roger, Dorman, Eric F., Emery, Robert C., Woodle, Douglas R., Manger, Ronald L., Nartea, Margaret, Kenoyer, Aimee L., Orozco, Johnnie J., Green, Damian J., Press, Oliver W., Storb, Rainer, Sandmaier, Brenda M., Wilbur, D. Scott“…The preparations were found to be sterile and have a pyrogen level <0.50 EU/mL. Cell binding was retained by the (211)At-BC8-B10. (211)At-BC8-B10 in ascorbic acid solution demonstrated a radiochemical stability of >95% for up to 21 h at room temperature. …”
Publicado 2018
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23993por Schwarzfischer, Phillipp, Gruszfeld, Dariusz, Socha, Piotr, Luque, Veronica, Closa-Monasterolo, Ricardo, Rousseaux, Déborah, Moretti, Melissa, Mariani, Benedetta, Verduci, Elvira, Koletzko, Berthold, Grote, Veit“…SUBJECTS/METHODS: Data were drawn from the EU Childhood Obesity Project (CHOP). PA and SB were measured with the SenseWear Armband 2 at the ages of 6 (T1), 8 (T2) and 11 (T3) years. …”
Publicado 2018
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23994por Amaro, João, Magalhães, João, Leite, Margarida, Aguiar, Beatriz, Ponte, Paula, Barrocas, Joana, Norton, Pedro“…INTRODUCTION: Healthcare workers account for 10% of the EU’s total workforce, with a significant proportion of those employed in hospitals. …”
Publicado 2018
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23995por Buck, Christoph, Loyen, Anne, Foraita, Ronja, Van Cauwenberg, Jelle, De Craemer, Marieke, Mac Donncha, Ciaran, Oppert, Jean-Michel, Brug, Johannes, Lien, Nanna, Cardon, Greet, Pigeot, Iris, Chastin, Sebastien“…Bayesian networks were estimated for the complete (23,865 EU-citizens with complete data) sample and for sex- and four age-specific subgroups. …”
Publicado 2019
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23996por Högler, Wolfgang, Langman, Craig, Gomes da Silva, Hugo, Fang, Shona, Linglart, Agnès, Ozono, Keiichi, Petryk, Anna, Rockman-Greenberg, Cheryl, Seefried, Lothar, Kishnani, Priya S.“…TRIAL REGISTRATION: Clinicaltrials.gov: NCT02306720, December 2014; ENCePP.eu: EUPAS13526, May 2016 (retrospectively registered).…”
Publicado 2019
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23997por Stacey, Brett R., Liss, Jonathan, Behar, Regina, Sadosky, Alesia, Parsons, Bruce, Masters, Elizabeth T., Hlavacek, Patrick“…Pregabalin is endorsed as first-line therapy for these indications by several US and EU medical professional societies. However, restriction policies such as prior authorization (PA) and step therapy (ST) often favor less costly generic pain medications over pregabalin. …”
Publicado 2017
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23998Walking pathways with positive feedback loops reveal DNA methylation biomarkers of colorectal cancerpor Kel, Alexander, Boyarskikh, Ulyana, Stegmaier, Philip, Leskov, Leonid S., Sokolov, Andrey V., Yevshin, Ivan, Mandrik, Nikita, Stelmashenko, Daria, Koschmann, Jeannette, Kel-Margoulis, Olga, Krull, Mathias, Martínez-Cardús, Anna, Moran, Sebastian, Esteller, Manel, Kolpakov, Fedor, Filipenko, Maxim, Wingender, Edgar“…RESULTS: In this paper, we analysed an extensive collection of full genome gene-expression data (RNA-seq) and DNA methylation data of genomic CpG islands (using Illumina methylation arrays) generated from a sample of tumor and normal gut epithelial tissues of 300 patients with colorectal cancer (at different stages of the disease) (data generated in the EU-supported SysCol project). Identification of potential epigenetic biomarkers of DNA methylation was performed using the fully automatic multi-omics analysis web service “My Genome Enhancer” (MGE) (my-genome-enhancer.com). …”
Publicado 2019
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23999por Tuyaerts, Sandra, Van Nuffel, An M. T., Naert, Eline, Van Dam, Peter A., Vuylsteke, Peter, De Caluwé, Alex, Aspeslagh, Sandrine, Dirix, Piet, Lippens, Lien, De Jaeghere, Emiel, Amant, Frédéric, Vandecasteele, Katrien, Denys, Hannelore“…Translational research is performed to discover biomarkers related to the mode of action of the combination. TRIAL REGISTRATION: EU Clinical Trials Register: EudraCT 2016-001569-97, registered on 19-6-2017. …”
Publicado 2019
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24000por Mose, F. H., Jörgensen, A. N., Vrist, M. H., Ekelöf, N. P., Pedersen, E. B., Bech, J. N.“…The clinical importance of these findings needs further investigation. TRIAL REGISTRATION: (EU Clinical trials register number: 2015–002585-23, registered on 5th November 2015)…”
Publicado 2019
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