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  1. 24221
    “…RESULTS: Compared to European norms, Swedish children in this sample scored lower on Physical wellbeing (48.8 SE/49.94 EU) but higher on the other KIDSCREEN-27 dimensions: Psychological wellbeing (53.4/49.77), Parent relations and autonomy (55.1/49.99), Social Support and peers (54.1/49.94) and School (55.8/50.01). …”
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    Children’s Quality of Life Based on the KIDSCREEN-27: Child Self-Report, Parent Ratings and Child-Parent Agreement in a Swedish Random Population Sample
  2. 24222
    “…TRIAL REGISTRATION: This trial was approved on July 2011 by the Ethics Committee of Policlinico Umberto I, Sapienza University of Rome, Italy, and registered at www.clinicaltrialsregister.eu number 2011-003010-17. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12916-016-0638-y) contains supplementary material, which is available to authorized users.…”
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    No effects of oral vitamin D supplementation on non-alcoholic fatty liver disease in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial
  3. 24223
    por Toumi, Mondher, Rémuzat, Cécile
    Publicado 2016
    “…Following completion of the literature review, a primary research was conducted to get perspective of various stakeholders across EU member states on drug repurposing (healthcare professionals, regulatory authorities and Health Technology Assessment (HTA) bodies/payers, patients, and representatives of the pharmaceutical industry developing medicines in this field). …”
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    Value added medicines: what value repurposed medicines might bring to society?
  4. 24224
    por Bousquet, J., Onorato, G. L., Bachert, C., Barbolini, M., Bedbrook, A., Bjermer, L., de Sousa, J. Correia, Chavannes, N. H., Cruz, A. A., De Manuel Keenoy, E., Devillier, P., Fonseca, J., Hun, S., Kostka, T., Hellings, P. W., Illario, M., Ivancevich, J. C., Larenas-Linnemann, D., Millot-Keurinck, J., Ryan, D., Samolinski, B., Sheikh, A., Yorgancioglu, A., Agache, I., Arnavielhe, S., Bewick, M., Annesi-Maesano, I., Anto, J. M., Bergmann, K. C., Bindslev-Jensen, C., Bosnic-Anticevich, S., Bouchard, J., Caimmi, D. P., Camargos, P., Canonica, G. W., Cardona, V., Carriazo, A. M., Cingi, C., Colgan, E., Custovic, A., Dahl, R., Demoly, P., De Vries, G., Fokkens, W. J., Fontaine, J. F., Gemicioğlu, B., Guldemond, N., Gutter, Z., Haahtela, T., Hellqvist-Dahl, B., Jares, E., Joos, G., Just, J., Khaltaev, N., Keil, T., Klimek, L., Kowalski, M. L., Kull, I., Kuna, P., Kvedariene, V., Laune, D., Louis, R., Magnan, A., Malva, J., Mathieu-Dupas, E., Melén, E., Menditto, E., Morais-Almeida, M., Mösges, R., Mullol, J., Murray, R., Neffen, H., O’Hehir, R., Palkonen, S., Papadopoulos, N. G., Passalacqua, G., Pépin, J. L., Portejoie, F., Price, D., Pugin, B., Raciborski, F., Simons, F. E. R., Sova, M., Spranger, O., Stellato, C., Todo Bom, A., Tomazic, P. V., Triggiani, M., Valero, A., Valovirta, E., VandenPlas, O., Valiulis, A., van Eerd, M., Ventura, M. T., Wickman, M., Young, I., Zuberbier, T., Zurkuhlen, A., Senn, A.
    Publicado 2017
    “…SUNFRAIL (Reference Sites Network for Prevention and Care of Frailty and Chronic Conditions in community dwelling persons of EU Countries), a European Union project, assessed whether MASK is in line with the 28 items of JA-CHRODIS. …”
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    CHRODIS criteria applied to the MASK (MACVIA-ARIA Sentinel NetworK) Good Practice in allergic rhinitis: a SUNFRAIL report
  5. 24225
    por Schormair, Barbara, Zhao, Chen, Bell, Steven, Tilch, Erik, Salminen, Aaro V, Pütz, Benno, Dauvilliers, Yves, Stefani, Ambra, Högl, Birgit, Poewe, Werner, Kemlink, David, Sonka, Karel, Bachmann, Cornelius G, Paulus, Walter, Trenkwalder, Claudia, Oertel, Wolfgang H, Hornyak, Magdolna, Teder-Laving, Maris, Metspalu, Andres, Hadjigeorgiou, Georgios M, Polo, Olli, Fietze, Ingo, Ross, Owen A, Wszolek, Zbigniew, Butterworth, Adam S, Soranzo, Nicole, Ouwehand, Willem H, Roberts, David J, Danesh, John, Allen, Richard P, Earley, Christopher J, Ondo, William G, Xiong, Lan, Montplaisir, Jacques, Gan-Or, Ziv, Perola, Markus, Vodicka, Pavel, Dina, Christian, Franke, Andre, Tittmann, Lukas, Stewart, Alexandre F R, Shah, Svati H, Gieger, Christian, Peters, Annette, Rouleau, Guy A, Berger, Klaus, Oexle, Konrad, Di Angelantonio, Emanuele, Hinds, David A, Müller-Myhsok, Bertram, Winkelmann, Juliane
    Publicado 2017
    “…METHODS: In the discovery stage, we combined three GWAS datasets (EU-RLS GENE, INTERVAL, and 23andMe) with diagnosis data collected from 2003 to 2017, in face-to-face interviews or via questionnaires, and involving 15 126 cases and 95 725 controls of European ancestry. …”
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    Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis
  6. 24226
    “…METHODS: The data used in this work comes from work package 2 (WP2) (entitled “Functional Enviromics”) of The European Union (EU)-funded European Network Study of Gene-Environment Interactions (EUGEI). …”
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    T104. ASSESSING THE UTILITY OF COPULA FUNCTIONS FOR RISK PREDICTION OF PSYCHOSIS
  7. 24227
    “…Notable differences existed in cause-specific mortality rates between the European subregions, from a two-times difference for leukaemia to a 20-times difference for lower respiratory infections between the Commonwealth of Independent States (CIS) and EU15 (the 15 member states that had joined the European Union before May, 2004). …”
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    Causes of death among children aged 5–14 years in the WHO European Region: a systematic analysis for the Global Burden of Disease Study 2016
  8. 24228
    “…METHOD: Ten hypothyroid, untreated patients (hypoHT), 10 hypothyroid cases rendered euthyroid by l-thyroxine therapy (substHT), 11 spontaneously euthyroid HT subjects (euHT), and 10 healthy controls (ctrl) were probed for three candidate immunoregulatory miRNA (miR-9-5p, miR-29a-3p, and miR-210-3p) using quantitative real-time PCR measurements. …”
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    miR-29a-3p/T-bet Regulatory Circuit Is Altered in T Cells of Patients With Hashimoto’s Thyroiditis
  9. 24229
    “…This strain is classified as sequence type 11 (ST11), and a core genome phylogenetic analysis indicated that strain GSU10-3 is closely related to KPC-2-positive Chinese clinical isolates from 2011 to 2017 and is clearly distinct from strains isolated from the European Union (EU), United States, and other Asian countries. Strain GSU10-3 harbors four plasmids, including a bla(KPC-2)-positive plasmid, pGSU10-3-3 (66.2 kb), which is smaller than other bla(KPC-2)-positive plasmids and notably carries dual replicons (IncFII [pHN7A8] and IncN). …”
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    Complete Genome Sequence of a bla(KPC-2)-Positive Klebsiella pneumoniae Strain Isolated from the Effluent of an Urban Sewage Treatment Plant in Japan
  10. 24230
    “…This study is registered as an International Standard Randomised Controlled Trial, number ISRCTN49141214, and the EU Clinical Trials register (EudraCT) number is 2010-022463-35I. …”
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    The benefit of minocycline on negative symptoms of schizophrenia in patients with recent-onset psychosis (BeneMin): a randomised, double-blind, placebo-controlled trial
  11. 24231
    “…FINDINGS: The percentage of children living at addresses exceeding the EU limit value for annual NO(2) (40 μg/m(3)) fell from 99% (444/450) in 2009 to 34% (150/441) in 2013. …”
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    Impact of London's low emission zone on air quality and children's respiratory health: a sequential annual cross-sectional study
  12. 24232
    “…TRIAL REGISTRATION: Clinicaltrialsregister.eu 2015-000199-86 and ClinicalTrials.gov NCT02546050 FUNDING: This project was funded by Danish Diabetes Association and The Novo Nordisk Foundation ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s00125-019-4848-7) contains peer-reviewed but unedited supplementary material, which is available to authorised users.…”
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    Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study
  13. 24233
    “…Funding: Ministerio de Economia y Competitividad, Agencia Estatal de Investigación (AEI) and Fondo Europeo de Desarrollo Regional (FEDER), EU Grants SAF2014-58335-P, BFU2017-86579-R, BFU2016-77125-R and Generalitat Valenciana PROMETEO II/2015/016. …”
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    OR23-3 Differential Effects of Chronic Exposure to Bisphenol-A on Ion Channel Activity and Expression in Mouse Pancreatic Beta-Cells
  14. 24234
    “…Average blood glucose concentrations at presentation were 329 + 36 mg/dl, interestingly, 52% of the episodes were euglycemic DKA (euDKA) with blood glucose <300 mg/dl. Average anion gap values were 25+1.4 mg/dl, bicarbonate 12.6+1.3 mg/dl and pH 7.17+0.03. …”
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    OR31-1 Sodium-Glucose Co-Transporter-2 Inhibitors and the Risk of Diabetic Ketoacidosis: Clinical and Biochemical Characteristics of 21 Cases
  15. 24235
    “…The PCL NPs removed greater than 90% LPS from protein solutions suspended in water using only one milligram (mg) of NPs, which was equivalent to ~1.5 × 10(6) endotoxin units (EU) per mg of particle. The LPS removal efficacy increased to a higher level (~100%) when phosphate buffered saline (PBS containing 137 mM NaCl) was used as a protein suspending medium in place of water, reflecting positive effects of increasing ionic strength on LPS binding interactions and adsorption. …”
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    PolyBall: A new adsorbent for the efficient removal of endotoxin from biopharmaceuticals
  16. 24236
    “…TRIAL REGISTRATION: ISRCTN.org identifier: 46020948; clinicaltrialsregister.eu identifier: 2006-000811-12…”
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    Safety and Efficacy of the Addition of Lapatinib to Perioperative Chemotherapy for Resectable HER2-Positive Gastroesophageal Adenocarcinoma: A Randomized Phase 2 Clinical Trial
  17. 24237
    “…DATA SOURCES: Relevant studies published between June 1983 and April 2018 from Medline, Embase, Cochrane Library for clinical trials, PubMed, Web of Science, ClinicalTrials.gov, and Clinicaltrialsregister.eu. REVIEW METHODS: Randomised controlled trials comparing two of the three durations of DAPT (short term, standard term, and long term) after PCI with DES were included. …”
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    Duration of dual antiplatelet therapy after percutaneous coronary intervention with drug-eluting stent: systematic review and network meta-analysis
  18. 24238
    “…Further, the combined application found to enhance the activities of defense related enzymes viz. catalase (5.92 EU min(–1) g(–1) fresh wt.), ascorbate peroxidase [μmol ascorbate oxidized (mg prot)(–1) min(–1)], phenylalanine ammonia lyase (102.25 μmol cinnamic acid h(–1) mg(–1) fresh wt.) and peroxidase (6.95 Unit mg(–1) min(–1) fresh wt.) significantly in the plants under treatment which was further confirmed by assessing the transcript level of PAL and peroxidase genes using semi-quantitative PCR approach. …”
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    Trichoderma harzianum- and Methyl Jasmonate-Induced Resistance to Bipolaris sorokiniana Through Enhanced Phenylpropanoid Activities in Bread Wheat (Triticum aestivum L.)
  19. 24239
    “…MHD has been described as a challenge in Norwegian pig production over the last decade despite abundant supplies of vitamin E, and selenium (Se) close to the upper limits set by the EU. From 2015 to 2017, samples from documented MHD field cases were collected and compared with controls regarding post mortem findings and Se concentrations in numerous internal and external organs were determined in order to characterize the Se distribution, and to identify any differences between MHD cases and controls. …”
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    A descriptive report of the selenium distribution in tissues from pigs with mulberry heart disease (MHD)
  20. 24240
    “…This is in concordance with the current EU licence for liraglutide (maximum dosage 3.0 mg). …”
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    Liraglutide and the management of overweight and obesity in people with schizophrenia, schizoaffective disorder and first-episode psychosis: protocol for a pilot trial
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