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  1. 24261
    “…En comparaison avec les formes non sévères, les formes sévères ont eu plus de fièvre (93 % vs 56 %, p < 0,01), de toux (71 % vs 38 %, p = 0,02), et de dyspnée (43 % vs 6 %, p < 0,01). …”
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    Le rapport polynucléaire neutrophile/lymphocyte comme marqueur prédictif précoce de COVID-19 sévère
  2. 24262
    “…FUNDING: German Research Foundation, Federal State of Hamburg, EU (eRARE), German Center for Infection Research (DZIF).…”
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    Neuropathology of patients with COVID-19 in Germany: a post-mortem case series
  3. 24263
    “…Predictor variables in both data sets: age, sex, morbidity-related variables (disease count), medication-related variables (European Union-Potentially Inappropriate Medication list (EU-PIM list)) and health service utilisation. Predictor variables exclusively in trial data: additional socio-demographics, morbidity-related variables (Cumulative Illness Rating Scale, depression), Medication Appropriateness Index (MAI), lifestyle, functional status and HRQoL (EuroQol EQ-5D-3L). …”
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    Development and internal validation of prognostic models to predict negative health outcomes in older patients with multimorbidity and polypharmacy in general practice
  4. 24264
    Publicado 2020
    “…FUNDING: Wellcome Trust, AstraZeneca Young Health Programme, EU.…”
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    Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants
  5. 24265
    “…We also show that antibody-positive participants with symptoms compatible with a respiratory tract infection had significantly higher antibody levels then asymptomatic participants (EU-assay: median 2.9 versus 7.2 IgG-index, p 0.002; DS-assay: median 45.2 versus 143 AU/mL, p 0.002). …”
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    Antibody response using six different serological assays in a completely PCR-tested community after a coronavirus disease 2019 outbreak—the CoNAN study
  6. 24266
    “…TRIAL REGISTRATION: The EU Clinical Trials Register 2020-001739-28. Registered on April 10, 2020. …”
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    A randomized, open-label, adaptive, proof-of-concept clinical trial of modulation of host thromboinflammatory response in patients with COVID-19: the DAWn-Antico study
  7. 24267
    “…METHODS: As a part of the international multidisciplinary SILICOFCM project (www.silicofcm.eu) the present study evaluated the association between underlying genetic mutations and clinical phenotype in patients with HCM. …”
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    Genetic determinants of clinical phenotype in hypertrophic cardiomyopathy
  8. 24268
    “…BACKGROUND: Cefiderocol (CFDC) is the first siderophore cephalosporin approved (US and EU) for a broad range of infections caused by Gram-negative (GN) bacteria, including carbapenem-resistant Enterobacterales (ENT) and non-fermenters (NFs). …”
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    1285. Outcomes in Patients with Gram-Negative Bacteremia from Phase 2 and Phase 3 Clinical Trials of Cefiderocol, a Novel Siderophore Cephalosporin
  9. 24269
    “…The MEDEA clinical intervention study in children with asthma is funded by EU LIFE+ program to evaluate the efficacy of recommendations aiming to reduce exposure to desert dust and related health effects. …”
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    The MEDEA childhood asthma study design for mitigation of desert dust health effects: implementation of novel methods for assessment of air pollution exposure and lessons learned
  10. 24270
    “…FUNDING: National Institute for Health Research (NIHR), UK Medical Research Council, Wellcome Trust, Department for International Development, Bill & Melinda Gates Foundation, EU Platform for European Preparedness Against (Re-)emerging Epidemics, NIHR Health Protection Research Unit (HPRU) in Emerging and Zoonotic Infections at University of Liverpool, NIHR HPRU in Respiratory Infections at Imperial College London.…”
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    Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study
  11. 24271
    “…An antibody against cTnC in the cTnI-C complex labeled with Eu(3+) was used to detect the cTnI-C complex, and an antibody labeled with Sm(3+) near the C-terminal 190–203 amino acids of cTnI was used to detect full-size-cTnI. …”
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    Establishment and Application of a Dual-Labeling Time-Resolved Fluorescence Immunoassay Method for Simultaneous Detection of the Troponin I-C Complex and Full-Size-Troponin I
  12. 24272
    “…The analogous design of other parallel trials of the DAWN consortium will amplify the chance of identifying successful treatment strategies and allow comparison of treatment effects within an identical clinical context. TRIAL REGISTRATION: EU Clinical trials register EudraCT Nb 2020-001614-38. …”
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    Direct antivirals working against the novel coronavirus: azithromycin (DAWn-AZITHRO), a randomized, multicenter, open-label, adaptive, proof-of-concept clinical trial of new antivirals working against SARS-CoV-2—azithromycin trial
  13. 24273
    “…The short version of the European Health Literacy Questionnaire (HLS-EU-Q16, ranging 0 to 16 points) was applied to assess the individual self-reported HL. …”
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    Low health literacy is associated with higher risk of type 2 diabetes: a cross-sectional study in Germany
  14. 24274
    “…We examined the antimicrobial susceptibility/resistance of gonococcal isolates (n = 15,803) collected across 27 European Union/European Economic Area (EU/EEA) countries in 2009–2016, in conjunction to epidemiological and clinical data of the corresponding patients, to elucidate associations between antimicrobial susceptibility/resistance and patients’ gender, sexual orientation and anatomical site of infection. …”
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    Associations between antimicrobial susceptibility/resistance of Neisseria gonorrhoeae isolates in European Union/European Economic Area and patients’ gender, sexual orientation and anatomical site of infection, 2009–2016
  15. 24275
    “…INTRODUCTION: La crise sanitaire liée au SARS-CoV-2 a eu des répercussions importantes sur la prise en charge des accidents vasculaires cérébraux (AVC) dans les hôpitaux, notamment dans les unités neurovasculaires (UNV). …”
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    Prise en charge des AVC en période d’épidémie COVID-19 dans 15 UNV d’Île-de-France : étude rétrospective sur 3 mois de mars à mai en comparant 2020 à 2019
  16. 24276
    “…DISCUSSION: Le confinement n’a pas eu de retentissement sur le nombre global d’AVC au CHUM mais a diminué le nombre de patients en alerte thrombolyse et majoré les délais de prise en charge. …”
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    Impact de l’épidémie de COVID-19 sur la prise en charge en phase aiguë de l’accident vasculaire cérébral au CHU de la Martinique
  17. 24277
    “…Parmi les patients, 38 % n’ont pas eu accès aux PDS principalement les kinésithérapeutes, médecins traitants et spécialistes. …”
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    CONFISEP : impact du confinement sur la prise en charge des patients atteints de sclérose en plaques
  18. 24278
    “…CONCLUSION: Il n’y a pas eu d’augmentation des effets indésirables au cours d’ITO pendant la période du confinement. …”
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    Impact du confinement sur le suivi des immunothérapies orales alimentaires : étude multi-centrique dans 3 centres d’Île de France
  19. 24279
    “…Moreover, HDB1258 treatment shifted gut microbiota composition in mice with and without LPS-induced systemic inflammation: it increased the Cyanobacteria and PAC000664_g (belonging to Bacteroidetes) populations and reduced Deferribacteres and EU622763_s group (belonging to Bacteroidetes) populations. …”
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    Lactobacillus rhamnosus HDB1258 modulates gut microbiota-mediated immune response in mice with or without lipopolysaccharide-induced systemic inflammation
  20. 24280
    “…Registered September 302,019, https://www.clinicaltrialsregister.eu/ctr-search/search?query=2019-001828-36…”
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    Brigatinib versus other second-generation ALK inhibitors as initial treatment of anaplastic lymphoma kinase positive non-small cell lung cancer with deep phenotyping: study protocol of the ABP trial
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