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24421por Popovic, David, Ruef, Anne, Dwyer, Dominic B, Hedderich, Dennis, Antonucci, Linda A, Kambeitz-Ilankovic, Lana, Öztürk, Ömer F, Dong, Mark S, Paul, Riya, Kambeitz, Joseph, Ruhrmann, Stephan, Chisholm, Katharine, Schultze-Lutter, Frauke, Falkai, Peter, Bertolino, Alessandro, Lencer, Rebekka, Dannlowski, Udo, Upthegrove, Rachel, Salokangas, Raimo K R, Pantelis, Christos, Meisenzahl, Eva, Wood, Stephen, Brambilla, Paolo, Borgwardt, Stefan, Koutsouleris, Nikolaos“…METHODS: We acquired our dataset from the multi-center European PRONIA cohort (www.pronia.eu). Specifically, we selected 649 male and female individuals, comprising young, minimally medicated patients with clinical high-risk states for psychosis as well as recent-onset of depression or psychosis and healthy volunteers. …”
Publicado 2020
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24422por Hauke, Daniel, Schmidt, André, Studerus, Erich, Andreou, Christina, Riecher-Rössler, Anita, Radua, Joaquim, Kambeitz, Joseph, Ruef, Anne, Dwyer, Dominic, Sanfelici, Rachele, Penzel, Nora, Haas, Shalaila, Antonucci, Linda, Schultze-Lutter, Frauke, Ruhrmann, Stephan, Hietala, Jarmo, Brambilla, Paolo, Koutsouleris, Nikolaos, Meisenzahl, Eva, Pantelis, Christos, Rosen, Marlene, Salokangas, Raimo K R, Upthegrove, Rachel, Wood, Stephen, Borgwardt, Stefan“…METHODS: We analyzed data from the ‘Personalized Prognostic Tools for Early Psychosis Management’ (PRONIA; www.pronia.eu) study, which consisted of 94 individuals at clinical high-risk of developing psychosis (CHR). …”
Publicado 2020
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24423por Maier, Franziska, Spottke, Annika, Bach, Jan-Philipp, Bartels, Claudia, Buerger, Katharina, Dodel, Richard, Fellgiebel, Andreas, Fliessbach, Klaus, Frölich, Lutz, Hausner, Lucrezia, Hellmich, Martin, Klöppel, Stefan, Klostermann, Arne, Kornhuber, Johannes, Laske, Christoph, Peters, Oliver, Priller, Josef, Richter-Schmidinger, Tanja, Schneider, Anja, Shah-Hosseini, Kija, Teipel, Stefan, von Arnim, Christine A. F., Wiltfang, Jens, Jessen, Frank“…CONCLUSIONS AND RELEVANCE: Although it is safe, bupropion was not superior to placebo for the treatment of apathy in patients with dementia of Alzheimer type in the absence of clinically relevant depressed mood. TRIAL REGISTRATION: EU Clinical Trials Register Identifier: 2007-005352-17…”
Publicado 2020
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24424por Jung-Schroers, Verena, Hildebrandt, Uta, Retter, Karina, Esser, Karl-Heinz, Hellmann, John, Kleingeld, Dirk Willem, Rohn, Karl, Steinhagen, Dieter“…A large percentage of rainbow trout produced by these small enterprises is marketed directly and killed on demand and not processed in commercial processing plants. EU and national regulations stipulate that fish shall be stunned prior to killing and slaughter. …”
Publicado 2020
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24425por Garcia-Suarez, Jessica, Garcia Fernandez, Javier, Sanz, Sergio, Martinez Lopez, Daniel, Reques, Leticia, Forteza Gil, Alberto“…TRIAL REGISTRATION: European Union Drug Regulating Authorities Clinical Trials Database (EudraCT) 2017-005144-14; https://www.clinicaltrialsregister.eu/ctr-search/search?query=2017-005144-14+; ClinicalTrials.gov NCT04094168; https://clinicaltrials.gov/ct2/show/NCT04094168 INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/17826…”
Publicado 2020
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24426por Karray, R., Jamoussi, A., Ayed, S., Lakhdhar, D., Rachdi, E., Ben Khelil, J., Besbes, M.“…Le recours à la ventilation invasive était significativement plus fréquent chez les patients du G1 avec un p = 0,005. Trois patients ont eu une séance d’épuration extrarénale : intermittente (n = 2) et continue (n = 1). …”
Publicado 2020
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24427por Pullano, Giulia, Valdano, Eugenio, Scarpa, Nicola, Rubrichi, Stefania, Colizza, Vittoria“…FUNDING: Agence Nationale de la Recherche, EU, REACTing.…”
Publicado 2020
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24428“…BACKGROUND: Bicyclists are the road user group with the highest number of severe injuries in the EU, yet little is known about sickness absence (SA) and disability pension (DP) following such injuries. …”
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24429por Reinders, Ilse, Wijnhoven, Hanneke A H, Jyväkorpi, Satu K, Suominen, Merja H, Niskanen, Riikka, Bosmans, Judith E, Brouwer, Ingeborg A, Fluitman, Kristien S, Klein, Michel C A, Kuijper, Lothar D, van der Lubbe, Laura M, Olthof, Margreet R, Pitkälä, Kaisu H, Vijlbrief, Rachel, Visser, Marjolein“…METHODS AND ANALYSIS: The PRevention Of Malnutrition In Senior Subjects in the EU (PROMISS) trial examines the effect of personalised dietary advice aiming at increasing protein intake with or without advice regarding timing of protein intake to close proximity of usual physical activity, on change in physical functioning after 6 months among community-dwelling older adults (≥65 years) with a habitual protein intake of <1.0 g/kg adjusted (a)BW/day. …”
Publicado 2020
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24430por Ruiz-Antorán, Belén, Sancho-López, Aránzazu, Torres, Ferrán, Moreno-Torres, Víctor, de Pablo-López, Itziar, García-López, Paulina, Abad-Santos, Francisco, Rosso-Fernández, Clara M., Aldea-Perona, Ana, Montané, Eva, Aparicio-Hernández, Ruth M., Llop-Rius, Roser, Pedrós, Consuelo, Gijón, Paloma, Hernández-Carballo, Carolina, Pedrosa-Martínez, María J., Rodríguez-Jiménez, Consuelo, Prada-Ramallal, Guillermo, Cabrera-García, Lourdes, Aguilar-García, Josefa A., Sanjuan-Jimenez, Rocío, Ortiz-Barraza, Evelyn I., Sánchez-Chica, Enrique, Fernández-Cruz, Ana“…TRIAL REGISTRATION: European Union electronic Register of Post-Authorization Studies (EU PAS Register) identifier, EUPAS34415 ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s40121-020-00373-8) contains supplementary material, which is available to authorized users.…”
Publicado 2020
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24431por Ramos, Rosa, Chazot, Charles, Ferreira, Anibal, Di Benedetto, Attilio, Gurevich, Konstantin, Feuersenger, Astrid, Wolf, Melanie, Arens, Hans-Jürgen, Walpen, Sebastian, Stuard, Stefano“…METHODS: De-identified patient data were extracted from a clinical database (EuCliD®) for adult hemodialysis patients from France, Italy, Portugal, Russia and Spain who were newly prescribed SFOH for up to 1 year as part of routine clinical care. …”
Publicado 2020
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24432por Camp Montoro, Jordi, Boyle, Laura Ann, Solà-Oriol, David, Muns, Ramon, Gasa, Josep, Garcia Manzanilla, Edgar“…Although space allowance had no effect on growth performance, high number of body lesions in the lower space allowance indicates that space allowances equal or below 0.78 m(2)/pig are detrimental to the welfare of pigs despite following the EU legislation.…”
Publicado 2021
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24433por Monk, Phillip D, Marsden, Richard J, Tear, Victoria J, Brookes, Jody, Batten, Toby N, Mankowski, Marcin, Gabbay, Felicity J, Davies, Donna E, Holgate, Stephen T, Ho, Ling-Pei, Clark, Tristan, Djukanovic, Ratko, Wilkinson, Tom M A“…This trial is registered with Clinicaltrialsregister.eu (2020-001023-14) and ClinicalTrials.gov (NCT04385095); the pilot trial of inpatients with COVID-19 is now completed. …”
Publicado 2021
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24434por Pla, Indira, Sanchez, Aniel, Pors, Susanne Elisabeth, Pawlowski, Krzysztof, Appelqvist, Roger, Sahlin, K Barbara, Poulsen, Liv La Cour, Marko-Varga, György, Andersen, Claus Yding, Malm, Johan“…STUDY FUNDING/COMPETING INTEREST(S): The authors thank the financial support from ReproUnion, which is funded by the Interreg V EU programme. No conflict of interest was reported by the authors. …”
Publicado 2020
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24435“…CONCLUSIONS: The investigated compounds could not compete with the in vivo characteristics of the EuE-based PSMA inhibitor [(177)Lu]Lu-PSMA-10. Although two derivatives (3 and 11) were found to exhibit high affinities towards LNCaP cells, tumor uptake at 24 h p.i. was considerably low, while uptake in salivary glands remained unaffected. …”
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24436por Pöttgen, C., Gkika, E., Stahl, M., Abu Jawad, J., Gauler, T., Kasper, S., Trarbach, T., Herrmann, K., Lehmann, N., Jöckel, K.-H., Lax, H., Stuschke, M.“…Trial registration The present trial was registered as a phase I/II trial at the EudraCT database: Nr. 2005-006097-10 (https://www.clinicaltrialsregister.eu/ctr-search/trial/2005-006097-10/DE) and authorized to proceed on 2006-09-25.…”
Publicado 2021
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24437por Welzel, Tatjana, Winskill, Carolyn, Zhang, Nancy, Woerner, Andreas, Pfister, Marc“…METHODS: A systematic literature search for randomized clinical trials (RCTs) in PiRD treated with bDMARDs/JAK inhibitors was conducted on Medline, clinicaltrials.gov, clinicaltrialsregister.eu and conference abstracts as of July 2020. RCTs were included if (i) patients were aged ≤20 years, (ii) patients had a predefined rheumatic diagnosis and (iii) RCT reported predefined outcomes. …”
Publicado 2021
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24438por Corman, Victor M, Haage, Verena Claudia, Bleicker, Tobias, Schmidt, Marie Luisa, Mühlemann, Barbara, Zuchowski, Marta, Jo, Wendy K, Tscheak, Patricia, Möncke-Buchner, Elisabeth, Müller, Marcel A, Krumbholz, Andi, Drexler, Jan Felix, Drosten, Christian“…The AgPOCTs with limit of detections that approximate virus concentrations at which patients are infectious might enable shortcuts in decision making in various areas of health care and public health. FUNDING: EU's Horizon 2020 research and innovation programme, German Ministry of Research, German Federal Ministry for Economic Affairs and Energy, German Ministry of Health, and Bill & Melinda Gates Foundation.…”
Publicado 2021
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24439por Hozé, Nathanaël, Paireau, Juliette, Lapidus, Nathanaël, Tran Kiem, Cécile, Salje, Henrik, Severi, Gianluca, Touvier, Mathilde, Zins, Marie, de Lamballerie, Xavier, Lévy-Bruhl, Daniel, Carrat, Fabrice, Cauchemez, Simon“…INTERPRETATION: Our simple approach to estimate the proportion of adults that have been infected with SARS-CoV-2 can help to characterise the burden of SARS-CoV-2 infection, epidemic dynamics, and the performance of surveillance in different regions. FUNDING: EU RECOVER, Agence Nationale de la Recherche, Fondation pour la Recherche Médicale, Institut National de la Santé et de la Recherche Médicale (Inserm).…”
Publicado 2021
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24440por Hughes, Richard, Whitley, Louise, Schneble, Hans-Martin, Muros-Le-Rouzic, Erwan, Sauter, Annette, Pedotti, Rosetta, Köndgen, Harold“…La sévérité du COVID-19 était asymptomatique à modérée chez 143 pts (46,6 %), sévère chez 52 pts (16,9 %) et critique chez 15 pts (4,9 %). Il y a eu 17 cas mortels (5,5 %). DISCUSSION: À partir des données de Pharmacovigilance, la COVID-19 chez des pts SEP traités par OCR était généralement légère/modérée, ne nécessitant pas d’hospitalisation. …”
Publicado 2021
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