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24461por Zhang, Yuezhou, Folarin, Amos A, Sun, Shaoxiong, Cummins, Nicholas, Vairavan, Srinivasan, Bendayan, Rebecca, Ranjan, Yatharth, Rashid, Zulqarnain, Conde, Pauline, Stewart, Callum, Laiou, Petroula, Sankesara, Heet, Matcham, Faith, White, Katie M, Oetzmann, Carolin, Ivan, Alina, Lamers, Femke, Siddi, Sara, Vilella, Elisabet, Simblett, Sara, Rintala, Aki, Bruce, Stuart, Mohr, David C, Myin-Germeys, Inez, Wykes, Til, Haro, Josep Maria, Penninx, Brenda WJH, Narayan, Vaibhav A, Annas, Peter, Hotopf, Matthew, Dobson, Richard JB“…METHODS: Data used in this paper came from a major EU program, called the Remote Assessment of Disease and Relapse–Major Depressive Disorder, which was conducted in 3 European countries. …”
Publicado 2022
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24462por Acquadro, Michaël, Marrel, Alexia, Manso-Silván, Maria A., Guittet, Catherine, Joukoff, Sophie, Bertholet-Thomas, Aurélia“…CONCLUSIONS: Qualitative interviews show that dRTA and its treatment have a significant impact on QoL of patients and parents and that ADV7103 helps improve daily-life and reduces treatment burden, resulting in greater overall satisfaction of the patients and their families. Trial registration EU Clinical Trials Register, EudraCT 2013-003828-36 on the 3rd of September 2013.…”
Publicado 2022
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24463por Mayer, Katharina A., Budde, Klemens, Halloran, Philip F., Doberer, Konstantin, Rostaing, Lionel, Eskandary, Farsad, Christamentl, Anna, Wahrmann, Markus, Regele, Heinz, Schranz, Sabine, Ely, Sarah, Firbas, Christa, Schörgenhofer, Christian, Kainz, Alexander, Loupy, Alexandre, Härtle, Stefan, Boxhammer, Rainer, Jilma, Bernd, Böhmig, Georg A.“…DISCUSSION: Based on the hypothesis that felzartamab is able to halt the progression of ABMR via targeting antibody-producing PC and NK cells, we believe that our trial could potentially provide the first proof of concept of a new treatment in ABMR based on a prospective randomized clinical trial. TRIAL REGISTRATION: EU Clinical Trials Register (EudraCT) 2021-000545-40. …”
Publicado 2022
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24464por Andriuta, Daniela, Si-Ahmed, Cherifa, Roussel, Martine, Constans, Jean-Marc, Makki, Malek, Aarabi, Ardalan, Basille, Damien, Andrejak, Claire, Godefroy, Olivier“…PATIENTS ET MÉTHODES: Nous avons inclus 46 patients avec une plainte cognitive post-COVID-19 adressés au centre mémoire du CHU d’Amiens, ayant bénéficié d’une évaluation neuropsychologique, 36 d’entre eux ont eu une IRM cérébrale. Le score cognitif global G3 était la somme des scores z moyens qui prenait en compte les fonctions exécutives, le langage et la vitesse d’action. …”
Publicado 2022
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24465por Tenni, Brigitte, Moir, Hazel V. J., Townsend, Belinda, Kilic, Burcu, Farrell, Anne-Maree, Keegel, Tessa, Gleeson, Deborah“…They were: trade agreements (divided into EU FTAs and those that include the USA); use of TRIPS flexibilities (divided into compulsory licencing and parallel importation); patent expiry/generic entry/generic pathway (divided into comparative studies and single country studies); patent policies (also divided into comparative studies and single country studies) and TRIPS-plus rules (divided into data exclusivity, patent term extensions and secondary patenting). …”
Publicado 2022
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24466por Valcheva, Violeta, Perea, Claudia, Savova-Lalkovska, Tanya, Dimitrova, Albena, Radulski, Lukasz, Mokrousov, Igor, Marinov, Krustyu, Najdenski, Hristo, Bonovska, Magdalena“…The isolates were subdivided into 3 major phylogenetic groups. Type Mbovis-13 (Eu2 complex [western Europe and northern Africa]) included one isolate. …”
Publicado 2022
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24467por Verdikt, Roxane, Bendoumou, Maryam, Bouchat, Sophie, Nestola, Lorena, Pasternak, Alexander O., Darcis, Gilles, Avettand-Fenoel, Véronique, Vanhulle, Caroline, Aït-Ammar, Amina, Santangelo, Marion, Plant, Estelle, Douce, Valentin Le, Delacourt, Nadège, Cicilionytė, Aurelija, Necsoi, Coca, Corazza, Francis, Passaes, Caroline Pereira Bittencourt, Schwartz, Christian, Bizet, Martin, Fuks, François, Sáez-Cirión, Asier, Rouzioux, Christine, De Wit, Stéphane, Berkhout, Ben, Gautier, Virginie, Rohr, Olivier, Van Lint, Carine“…-FNRS, Belgium), the « Fondation Roi Baudouin », the NEAT (European AIDS Treatment Network) program, the Internationale Brachet Stiftung, ViiV Healthcare, the Télévie, the Walloon Region (« Fonds de Maturation »), « Les Amis des Instituts Pasteur à Bruxelles, asbl », the University of Brussels (Action de Recherche Concertée ULB grant), the Marie Skodowska Curie COFUND action, the European Union's Horizon 2020 research and innovation program under grant agreement No 691119-EU4HIVCURE-H2020-MSCA-RISE-2015, the French Agency for Research on AIDS and Viral Hepatitis (ANRS), the Sidaction and the “Alsace contre le Cancer” Foundation. …”
Publicado 2022
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24468“…On y trouvait 60 % (3) de femmes, 40 % (2) d’atopiques, un âge moyen : 50 ± 18 ans. Tous avaient eu une réaction immédiate (< 1 h), anaphylactique (choc anaphylactique dans 40 %, 2 cas)…”
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24469“…Il faut noter que les réactions urticariennes étaient toutes retardées de plus d’1 h ce qui est peu évocateur d’anaphylaxie IgE médiée. 217/225 patients ont eu une 2ème dose (dont 75 dans le service) parmi lesquels 2 ont présenté une réaction non grave non évocatrice d’allergie. …”
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24470por Shen, Chan, Tannenbaum, Daniel, Horn, Robert, Rogers, Jane, Eng, Cathy, Zhou, Shouhao, Johnson, Benny, Kopetz, Scott, Morris, Van, Overman, Michael, Parseghian, Christine, Chang, George J., Lopez-Olivo, Maria A., Kanwal, Raghav, Ellis, Lee M., Dasari, Arvind“…EVIDENCE REVIEW: Medline, EMBASE, Cochrane, Web of Science, ClinicalTrials.gov, EU Clinical Trials Register, and the International Clinical Trials Registry Platform were searched for phase 3 trials of systemic therapy for patients with mCRC by decade (1986-1996, 1997-2006, and 2007-2016), excluding early or pilot studies, studies that did not involve an anticancer drug, studies on cancer screening and prevention, reports of pooled data from multiple trials, and studies with nonpharmaceutical approaches. …”
Publicado 2022
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24471por Salmanton-García, Jon, Stewart, Fiona A., Heringer, Sarah, Koniordou, Markela, Álvarez-Barco, Elena, Argyropoulos, Christos D., Themistocleous, Sophia C., Valle-Simón, Paula, Spivak, Orly, Součková, Lenka, Merakou, Christina, Amélia Mendonça, Maria, Joanna Davis, Ruth, Maria Azzini, Anna, Askling, Helena H., Vene, Sirkka, Van Damme, Pierre, Steinbach, Angela, Shiamakkides, George, Seidel, Danila, Olesen, Ole F., Noula, Evgenia, Macken, Alan, Luís, Catarina, Leckler, Janina, Launay, Odile, Isitt, Catherine, Hellemans, Margot, Frías-Iniesta, Jesús, Di Marzo, Romina, Carcas, Antonio J., Boustras, George, Borobia, Alberto M., Barta, Imre, Albus, Kerstin, Akova, Murat, Ochando, Jordi, Cohen-Kandli, Miriam, Jane Cox, Rebecca, Husa, Petr, Jancoriene, Ligita, Mallon, Patrick, Marques, Laura, Mellinghoff, Sibylle C., Nauclér, Pontus, Tacconelli, Evelina, Tóth, Krisztina, Zaoutis, Theoklis E., Zeitlinger, Markus, Cornely, Oliver A., Pana, Zoi-Dorothea“…METHODS: Interested volunteers who would like to register for clinical trials in the VACCELERATE Volunteer Registry can access the registration questionnaire via http://www.vaccelerate.eu/volunteer-registry. Potential volunteers are requested to provide their current country and area of residence, contact information, including first and last name and e-mail address, age, gender, comorbidities, previous SARS-CoV-2 infection and vaccination status, and maximum distance willing to travel to a clinical trial site. …”
Publicado 2022
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24472por Kitchen, Helen, Wyrwich, Kathleen W., Carmichael, Chloe, Deal, Linda S., Lukic, Tatjana, Al-Zubeidi, Tamara, Marshall, Chris, Pegram, Hannah, Hamzavi, Iltefat H., King, Brett“…Expert dermatologists (N = 14) participated from the USA (n = 8), EU (n = 4), India (n = 1), and Egypt (n = 1). All individuals with vitiligo reported experiencing skin depigmentation; an observable clinical sign of vitiligo. …”
Publicado 2022
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24473por Kitchen, Helen, Gandhi, Kavita, Carmichael, Chloe, Wyrwich, Kathleen W., Lukic, Tatjana, Al-Zubeidi, Tamara, Marshall, Chris, Pegram, Hannah, King, Sharon, King, Brett“…Expert dermatologists from the US (n = 8), EU (n = 4), India (n = 1) and Egypt (n = 1) participated. …”
Publicado 2022
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24474por Souissi, D., Skhiri, A., Dhaouadi, N., Yaacoub, S. Ben, Harizi, C., Fakhfakh, R., Boujdaria, R.“…DISCUSSION/CONCLUSION: Notre étude nous a permis de déterminer la prévalence de la COVID longue dans un hôpital Tunisien et d’énumérer les symptômes résiduels les plus fréquents qui étaient : gêne respiratoire, troubles de la mémoire et asthénie. Ces symptômes ont eu un impact majeur sur la qualité de vie des patients. …”
Publicado 2022
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24475por Taengchaiyaphum, Suparat, Wongkhaluang, Prapatsorn, Sittikankaew, Kanchana, Karoonuthaisiri, Nitsara, Flegel, Timothy W., Sritunyalucksana, Kallaya“…Both PC35 clusters contained multiple sequences with high homology (99%) to GenBank records DQ228358 and EU675312 that were both called “non-infectious IHHNV Type A” (IHHNV-A) when originally discovered. …”
Publicado 2022
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24476por Marsden, John, Kelleher, Mike, Hoare, Zoë, Hughes, Dyfrig, Bisla, Jatinder, Cape, Angela, Cowden, Fiona, Day, Edward, Dewhurst, Jonathan, Evans, Rachel, Hearn, Andrea, Kelly, Joanna, Lowry, Natalie, McCusker, Martin, Murphy, Caroline, Murray, Robert, Myton, Tracey, Quarshie, Sophie, Scott, Gemma, Turner, Sophie, Vanderwaal, Rob, Wareham, April, Gilvarry, Eilish, Mitcheson, Luke“…If there is evidence for the superiority of BUP-XR over SOC medication, study findings will have substantial implications for OUD clinical practice and treatment policy in the UK and elsewhere. TRIAL REGISTRATION: EU Clinical Trials register 2018-004460-63. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13063-022-06595-0.…”
Publicado 2022
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24477por Singh, Haramandeep, Hyman, Danielle, Parks, Gregory S., Chen, Abby, Foley, Catherine, Baldys, Beth, Ito, Diane, Thorpy, Michael J.“…INTRODUCTION: Solriamfetol (Sunosi™), a dopamine/norepinephrine reuptake inhibitor, is approved (USA and EU) to treat excessive daytime sleepiness (EDS) in adults with obstructive sleep apnea (OSA) (37.5–150 mg/day). …”
Publicado 2022
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24478por Kandouci, Chahrazed, Meçabih, Fethi, Meçabih, Imen, Kadari, Chiffa, Megharbi, Nihad, Achouri, Mohamed Yacine, Kandouci, Baderdine Abdelkrim, Benabdelaziz, Ahmed“…CONCLUSION: En Algérie, la lutte contre la pandémie de COVID-19 a eu un impact sur la santé mentale des professionnels de santé. …”
Publicado 2022
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24479por Chemingui, Siwar, Ziedi, Hiba, Youssef, Imen, Ayed, Wiem, Rjab, Jihen, Ben Said, Hanene, Brahim, Dorra, Mersni, Meriem, Mechergui, Najla, Ladhari, Nizar“…INTRODUCTION: La pandémie COVID-19 a eu d’importantes répercussions sur la santé physique et psychologique des personnes ayant contracté le virus du SARS-CoV-2. …”
Publicado 2022
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24480por Chatterjee, Ayan, Prinz, Andreas, Gerdes, Martin, Martinez, Santiago, Pahari, Nibedita, Meena, Yogesh Kumar“…Furthermore, we performed a technological readiness study of ProHealth eCoach against standard levels set by European Union (EU). SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12913-022-08441-0.…”
Publicado 2022
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