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  1. 2201
    “…Although green tea (Camellia sinensis) (GT) contains a large number of polyphenolic compounds with anti‐oxidative and anti‐proliferative activities, little is known of the pharmacokinetics and tissue dose of tea catechins (TCs) as a chemical mixture in humans. …”
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    Physiologically based pharmacokinetic modeling of tea catechin mixture in rats and humans
  2. 2202
    “…BACKGROUND: Co-occurrence of multiple sclerosis (MS) and glial tumours (GT) is uncommon although occasionally reported in medical literature. …”
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    Anaplastic astrocytoma mimicking progressive multifocal leucoencephalopathy: a case report and review of the overlapping syndromes
  3. 2203
    “…The AG haplotype showed significantly greater expression of luciferase than the GT haplotype. We then overexpressed a blw cDNA construct driven by either the AG or GT haplotype promoter in transgenic flies and showed that the AG haplotype also results in greater blw cDNA expression and a significant decrease in lifespan relative to the GT promoter haplotype, in male flies only. …”
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    Regulation of Drosophila Lifespan by bellwether Promoter Alleles
  4. 2204
    “…Due to the lack of strand information, however, the percentage of identified GT-AG gap-sites is rather low. While gap-sites from TopHat contain ≈89% GT-AG, gap-sites from STAR only contain ≈42% GT-AG dinucleotide pairs in merged data from 54 fibroblast samples. …”
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    Validation of Splicing Events in Transcriptome Sequencing Data
  5. 2205
    “…γ-Glutamyltranspeptidases (γ-GTs), ubiquitous in glutathione metabolism for γ-glutamyl transfer/hydrolysis, are N-terminal nucleophile (Ntn)-hydrolase fold proteins that share an autoproteolytic process for self-activation. γ-GT homologues are widely present in Gram-positive actinobacteria where their Ntn-hydrolase activities, however, are not involved in glutathione metabolism. …”
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    4-alkyl-L-(Dehydro)proline biosynthesis in actinobacteria involves N-terminal nucleophile-hydrolase activity of γ-glutamyltranspeptidase homolog for C-C bond cleavage
  6. 2206
    “…Region-wide mass balances vary from -4.0 ± 1.5 Gt yr(-1) (-0.62 ± 0.23 m w.e. yr(-1)) in Nyainqentanglha to +1.4 ± 0.8 Gt yr(-1) (+0.14 ± 0.08 m w.e. yr(-1)) in Kunlun, with large intra-regional variability of individual glacier mass balances (standard deviation within a region ˜0.20 m w.e. yr(-1)). …”
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    A spatially resolved estimate of High Mountain Asia glacier mass balances, 2000-2016
  7. 2207
    “…In CDCl(3) solution, three staggered conformers, namely gt(+), gg(−) and tg, were randomized, while in more polar solvents, the gt(+) conformer with (+)-helicity was amplified at the expense of gg(−) and tg conformers. …”
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    Remarkable functions of sn-3 hydroxy and phosphocholine groups in 1,2-diacyl-sn-glycerolipids to induce clockwise (+)-helicity around the 1,2-diacyl moiety: Evidence from conformation analysis by (1)H NMR spectroscopy
  8. 2208
    “…The expression of both XT-I and GT-I was detected using immunohistochemistry. A significant decrease in GAGs was observed during the ageing process. …”
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    Ageing affects chondroitin sulfates and their synthetic enzymes in the intervertebral disc
  9. 2209
    “…Animals were subsequently challenged on a second rGT session with altered contingencies. Finally, animals were also assessed for instrumental conditioning and reversal learning. …”
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    The anterior insula bidirectionally modulates cost‐benefit decision‐making on a rodent gambling task
  10. 2210
    “…CONCLUSION: Retreatment with sofosbuvir and ledipasvir is effective for HCV GT-1b patients who discontinue the combination of daclatasvir and asunaprevir within 4 weeks. …”
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    Successful retreatment with sofosbuvir plus ledipasvir for cirrhotic patients with hepatitis C virus genotype 1b, who discontinued the prior treatment with asunaprevir plus daclatasvir: A case series and review of the literature
  11. 2211
    “…AIM: To investigate the real-world efficacy and safety of sofosbuvir/ribavirin (SOF/RBV) therapy for Japanese patients with genotype 2 hepatitis C virus (GT2-HCV). METHODS: A total of 182 patients with GT2-HCV infection who received SOF/RBV therapy for 12 wk at our hospital were enrolled. …”
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    Hepatocellular carcinoma or interferon-based therapy history attenuates sofosbuvir/ribavirin for Japanese genotype 2 hepatitis C virus
  12. 2212
    por Kim, Ju Young, Cho, Jinmin, Yang, Hye Ran
    Publicado 2018
    “…Elevated serum γGT and uric acid levels may serve as biochemical predictors in detecting NAFLD in young children with obesity before investigation with abdominal USG.…”
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    Biochemical Predictors of Early Onset Non-Alcoholic Fatty Liver Disease in Young Children with Obesity
  13. 2213
    “…The lines with almost WCF suppressed chalcone flavanone isomerase, while the lines with GCF highly expressed the glucosyl transferase (3GT) gene. Overexpression of the Gh3GT or Arabidopsis thaliana 3GT gene in BCF lines resulted in GCF. …”
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    Flavonoid biosynthesis controls fiber color in naturally colored cotton
  14. 2214
    “…We find that genomic regions enriched in high F(ST) SNPs colocalize with GT QTL peaks. Many of these high F(ST) regions also colocalize with regions enriched for SNPs significantly correlated to climate in Eurasia and evidence of recent selective sweeps in Sweden. …”
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    Combining population genomics and fitness QTLs to identify the genetics of local adaptation in Arabidopsis thaliana
  15. 2215
    “…GT/GG: adjusted OR=0.36, 95% CI=0.19-0.69, P=0.002] after adjustment for age and gender. …”
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    LMO1 super-enhancer polymorphism rs2168101 G>T correlates with decreased neuroblastoma risk in Chinese children
  16. 2216
    por Schneider, Jay S.
    Publicado 2018
    “…Reduced expression of GM1 and other major brain gangliosides GD1a, GD1b and GT1b have been reported in Parkinson’s disease (PD) brain. …”
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    Altered expression of genes involved in ganglioside biosynthesis in substantia nigra neurons in Parkinson’s disease
  17. 2217
    “…Z-VAD-FMK and GT3 also partially reversed the negative growth effects of droxinstat on HT-29 cells. …”
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    Droxinostat sensitizes human colon cancer cells to apoptotic cell death via induction of oxidative stress
  18. 2218
    “…Exposure‐response analysis supports the clinical utility of the combination regimen of 60‐mg once‐daily DCV and 100‐mg twice‐daily ASV in Japanese patients infected with HCV GT 1b.…”
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    Exposure‐Response (Efficacy) Analysis of Daclatasvir and Asunaprevir in Japanese Patients With Hepatitis C Virus Infection
  19. 2219
    por Xu, Jie, Guo, Wei, Xie, Lu
    Publicado 2018
    “…BACKGROUND: The combination of gemcitabine and docetaxel (GT) has been demonstrated to be effective against various types of solid tumors, including sarcoma. …”
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    Combination of gemcitabine and docetaxel: a regimen overestimated in refractory metastatic osteosarcoma?
  20. 2220
    “…The current study aimed to explore the effectiveness and safety of two regimens sofosbuvir (SOF) in combination with either ribavirin (RBV) or simeprevir (SMV) in chronic hepatitis C (CHC) genotype (GT) 4 patients in Egypt. METHODS: A total of 201 patients, treatment-naïve and experienced, with CHC GT4 infection were allocated into two groups based on the type of the regimen used. …”
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    Sofosbuvir in combination with ribavirin or simeprevir: real-life study of patients with hepatitis C genotype 4
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