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5641por Chasen, Nathan M., Stasic, Andrew J., Asady, Beejan, Coppens, Isabelle, Moreno, Silvia N. J.“…We characterized a Toxoplasma gondii gene (TgGT1_251630, TgZnT), which is annotated as the only ZnT family Zn(2+) transporter in T. gondii. …”
Publicado 2019
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5642por Jiang, Yan‐Ji, Zhong, Jian‐Hong, Zhou, Zi‐Han, Qiu, Mo‐Qin, Zhou, Xian‐Guo, Liu, Ying‐Chun, Huo, Rong‐Rui, Liang, Xiu‐Mei, Chen, Zhu, Lin, Qiu‐Ling, Yu, Xiang‐Yuan, Yu, Hong‐Ping“…According to the results of further stratification analysis, GT/GG genotype of rs28363292 increased HCC risk in zhuang people (OR = 3.913, 95% CI = 1.873‐8.175) and nonhepatitis B virus (HBV) infection population (OR = 1.774, 95% CI = 1.060‐2.969), the combined 1‐2 risk genotypes increased the risk of HCC in zhuang people (OR = 2.817, 95% CI = 1.532‐5.182) and non‐HBV infected population (OR = 1.567, 95% CI = 1.042‐2.358). …”
Publicado 2019
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5643“…Proinflammatory cytokines directly repress GnRH gene expression in GT1-7 cells model, while in vivo, obese males show activation of a cytokine-induced transcription factor in GnRH neurons. …”
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5644por Theodotou, Marios, Fokianos, Konstantinos, Moniatis, Demetris, Kadlenic, Rudolf, Chrysikou, Asimina, Aristotelous, Andrea, Mouzouridou, Alexia, Diakides, John, Stavrou, Eliza“…The study results showed the effects of Trans-resveratrol micronized formulation in reducing the liver fat, as well as decreasing hepatic enzymes, serum glutamate pyruvic transaminase (SGPT) and gamma-glutamyl transpeptidase (g-GT) and insulin resistance. At the end of the study, the statistical analysis showed a statistically significant reduction on the liver fat. …”
Publicado 2019
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5645por Hsu, Wei-Hsiang, Liao, Se-Chun, Chyan, Yau-Jan, Huang, Kai-Wen, Hsu, Shih-Lan, Chen, Yi-Chen, Siu, Ma-Li, Chang, Chia-Chuan, Chung, Yuh-Shan, Huang, Chi-Ying F.“…Moreover, the HH-F3 fraction decreased hepatic collagen content and reduced plasma AST, ALT, and γ-GT activities in a DEN-induced rat liver injury model, suggesting that GP/HH-F3 has hepatoprotective effects against DEN-induced liver fibrosis. …”
Publicado 2019
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5646“…BACKGROUND: To improve the outcome of cancer treatment, the combination of multiple therapy models has proved to be effective and promising. Gas therapy (GT) and chemodynamic therapy (CDT), mainly targeting the mitochondrion and nucleus, respectively, are two emerging strategy for anti-cancer. …”
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5647por Anacleto, Roslen, Badoni, Saurabh, Parween, Sabiha, Butardo, Vito M., Misra, Gopal, Cuevas, Rosa Paula, Kuhlmann, Markus, Trinidad, Trinidad P., Mallillin, Aida C., Acuin, Cecilia, Bird, Anthony R., Morell, Matthew K., Sreenivasulu, Nese“…The low GI line with GC haplotype confirmed soft texture, while other two low GI lines with GT haplotype were characterized as hard and cohesive. …”
Publicado 2019
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5648“…Furthermore, ALT, AST, ALP, γ-GT, TBIL, and other indexes were positively correlated to the Th17/Treg ratio (P <.05). …”
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5649por Full, Kelsie M., Moran, Kevin, Carlson, Jordan, Godbole, Suneeta, Natarajan, Loki, Hipp, Aaron, Glanz, Karen, Mitchell, Jonathan, Laden, Francine, James, Peter, Kerr, Jacqueline“…Participants wore ActiGraph GT3X+ accelerometers on the hip and wrist for a week. …”
Publicado 2019
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5650por Loo, Nicole, Hanysak, Bryan, Mann, Jena, Ramirez, Ruben, Kim, Jae, Mitchell, Robert, Van Frank, Timothy, Guerrero, Richard, Hinojosa, Kim, Christensen, Kimberley, Pedicone, Lisa D., Alkhouri, Naim, Wells, Jennifer, Landaverde, Carmen, Rodas, Fabian, Lawitz, Eric, Poordad, Fred“…A total of 875 chronic, mostly GT1a (60%) HCV patients were treated with an approved DAA regimen. …”
Publicado 2019
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5651por Yamana, Masaki, Kuwahara, Motoi, Fukumoto, Yuta, Yoshikawa, Keisuke, Takada, Kazuo, Kusunoki, Susumu“…RESULTS: The anti-GQ1b seropositivity rate was significantly higher, whereas the GM1 and GD1a seropositivity rates were significantly lower in GBSRD-I compared with GBSRD-C. Anti-GQ1b and anti-GT1a were the most frequently detected antiglycolipid antibodies in GBSRD-I (both 15/63, 24%). …”
Publicado 2019
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5652por Marisi, Giorgia, Petracci, Elisabetta, Raimondi, Francesco, Faloppi, Luca, Foschi, Francesco Giuseppe, Lauletta, Gianfranco, Iavarone, Massimo, Canale, Matteo, Valgiusti, Martina, Neri, Luca Maria, Ulivi, Paola, Orsi, Giulia, Rovesti, Giulia, Vukotic, Ranka, Conti, Fabio, Cucchetti, Alessandro, Ercolani, Giorgio, Andrikou, Kalliopi, Cascinu, Stefano, Scartozzi, Mario, Casadei-Gardini, Andrea“…In particular, patients with ANGPT2rs55633437 TT/GT genotypes had significantly lower median OS (4.66 vs. 15.5 months, hazard ratio (HR) 4.86, 95% CI 2.73–8.67, p < 0.001) and PFS (1.58 vs. 6.27 months, HR 4.79, 95% CI 2.73–8.35, p < 0.001) than those homozygous for the G allele. …”
Publicado 2019
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5653por Zhang, Chen, Han, Fengjiao, Yu, Jie, Hu, Xiang, Hua, Mingqiang, Zhong, Chaoqin, Wang, Ruiqing, Zhao, Xueyun, Shi, Yufeng, Ji, Chunyan, Ma, Daoxin“…Moreover, we also found that AT and TT genotypes of CARD8 (rs2043211), GT and TT genotypes of IL-1β (rs16944), and TT genotype of IL-18 (rs1946518) were associated with higher mRNA expression of NLRP3 inflammasome related genes and secretion of downstream cytokines. …”
Publicado 2019
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5654por Yoo, Chan Yul, Mano, Noel, Finkler, Aliza, Weng, Hua, Day, Irene S., Reddy, Anireddy S. N., Poovaiah, B. W., Fromm, Hillel, Hasegawa, Paul M., Mickelbart, Michael V.“…Here we report a novel Ca(2+)/CaM signal transduction mechanism that allosterically regulates DNA-binding activity of GT2-LIKE 1 (GTL1), a transrepressor of STOMATAL DENSITY AND DISTRIBUTION 1 (SDD1), to repress stomatal development in response to water stress. …”
Publicado 2019
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5655Genetic and metabolic predictors of hepatic fat content in a cohort of Italian children with obesitypor Di Costanzo, Alessia, Pacifico, Lucia, Chiesa, Claudio, Perla, Francesco Massimo, Ceci, Fabrizio, Angeloni, Antonio, D’Erasmo, Laura, Di Martino, Michele, Arca, Marcello“…RESULTS: HFF% was positively related with BMI, HOMA(IR), metabolic syndrome, ALT, AST, γGT, and albumin. Carriers of [G] allele in PNPLA3, [T] allele in GCKR and [T] allele in TM6SF2 genes had significantly higher hepatic fat content than wild-type carriers. …”
Publicado 2019
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5656por Cho, Hyeon-Mu, Park, Sang-Je, Choe, Se-Hee, Lee, Ja-Rang, Kim, Sun-Uk, Jin, Yeung-Bae, Kim, Ji-Su, Lee, Sang-Rae, Kim, Young-Hyun, Huh, Jae-Won“…The combined MIR and AluSp sequences provide a 3′ splice site (AG) and 5′ splice site (GT), respectively, and generate the Old World monkey-specific transcripts. …”
Publicado 2019
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5657por Asadgol, Zahra, Mohammadi, Hamed, Kermani, Majid, Badirzadeh, Alireza, Gholami, Mitra“…To determine the best lag time and combination of inputs, Gamma Test (GT) was applied. General circulation model outputs were utilized to project future climate pattern under two scenarios of Representative Concentration Pathway (RCP2.6 and RCP8.5). …”
Publicado 2019
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5658“…Among patients at various disease stages, patients with immune activity showed the highest sPD‐1 levels (median 5.138 IQR 4.329‐5.406 pg/mL). sPD‐1 concentration was associated with HBV markers (HBsAg, HBV DNA and HBeAg) and biochemical parameters (serum aspartate aminotransferase [AST], alanine aminotransferase [ALT], total bilirubin [TBil] and gamma glutamyl transferase [γ‐GT] levels) (all P < 0.05). sPD‐1 levels were higher in CHB patients with moderate‐to‐severe inflammation or fibrosis than in those with mild inflammation or fibrosis, regardless of ALT levels. …”
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5659por Liu, Yinuo, Fang, Xibi, Zhao, Zhihui, Li, Junya, Albrecht, Elke, Schering, Lisa, Maak, Steffen, Yang, Runjun“…Moreover, three haplotypes (H1: AT; H2: AA; H3: GT) were identified by linkage disequilibrium analysis and formed six combined genotypes. …”
Publicado 2019
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5660“…To highlight the water potential of this region, the total ice mass loss has been estimated to be 16.0 ± 1.2 Gigatonne (Gt) from 2000–2014 from eight identified catchments namely Yamunotri, Bhagirathi, Mandakini, Alaknanda, Dhauliganga, Pindar, Goriganga and Kali/Sarda. …”
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